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1. 发明公开

EP2670485A1 AN APPARATUS FOR PARTICLE THERAPY VERIFICATION 有权
标题翻译：设备技术粒子治疗回顾
公开(公告)号：EP2670485A1
公开(公告)日：2013-12-11
申请号：EP12702533.6
申请日：2012-02-03
申请人： ION BEAM APPLICATIONS S.A. , Université Libre de Bruxelles
发明人： PRIEELS, Damien , STICHELBAUT, Frédéric , SMEETS, Julien , DUBUS, Alain , DEHAES, Jean-Claude
IPC分类号： A61N5/10 , G01T1/164 , A61N5/00
CPC分类号： A61N5/1071 , A61N5/1048 , A61N5/1075 , A61N2005/1052 , A61N2005/1087 , F04C2270/041 , G01T1/2914
摘要： The invention is related to an apparatus and method for charged hadron therapy verification by detecting and/or quantifying prompt gammas produced when irradiating a target (6) with a charged hadron beam. The apparatus comprises a collimator (1) provided with a slit-shaped portion (2) configured to be arranged perpendicularly to the beam line and facing the target, a detection means (3,4) suitable for detecting said prompt gammas and a calculation and representation means. In the apparatus and method of the invention, the slit is configured to allow the passage of prompt gammas emitted from a range of depths in said target (6), said depths being measured in the direction of the charged hadron beam. Furthermore, said detection means is configured to detect prompt gammas emitted from each location within said range, and said calculation and representation means is configured to derive from a detected prompt gamma a value representative of the dose at the location from where said prompt gamma is emitted, and to represent a dose-related distribution for a plurality of locations within said range.

2. 发明授权

EP2977083B1 AN APPARATUS FOR PARTICLE THERAPY VERIFICATION 有权
标题翻译：一种用于颗粒治疗验证的装置
公开(公告)号：EP2977083B1
公开(公告)日：2017-12-27
申请号：EP15181468.8
申请日：2012-02-03
申请人： ION BEAM APPLICATIONS S.A. , Université Libre de Bruxelles
发明人： PRIEELS, Damien , STICHELBAUT, Frédéric , SMEETS, Julien , DUBUS, Alain , DEHAES, Jean-Claude
IPC分类号： A61N5/10 , G01T1/164 , A61N5/00
CPC分类号： A61N5/1071 , A61N5/1048 , A61N5/1075 , A61N2005/1052 , A61N2005/1087 , F04C2270/041 , G01T1/2914
摘要： The invention is related to an apparatus and method for charged hadron therapy verification by detecting and/or quantifying prompt gammas produced when irradiating a target (6) with a charged hadron beam. The apparatus comprises a collimator (1) provided with a slit-shaped portion (2) configured to be arranged perpendicularly to the beam line and facing the target, a detection means (3,4) suitable for detecting said prompt gammas and a calculation and representation means. In the apparatus and method of the invention, the slit is configured to allow the passage of prompt gammas emitted from a range of depths in said target (6), said depths being measured in the direction of the charged hadron beam. Furthermore, said detection means is configured to detect prompt gammas emitted from each location within said range, and said calculation and representation means is configured to derive from a detected prompt gamma a value representative of the dose at the location from where said prompt gamma is emitted, and to represent a dose-related distribution for a plurality of locations within said range.

3. 发明授权

EP2670485B1 AN APPARATUS FOR PARTICLE THERAPY VERIFICATION 有权
标题翻译：设备技术粒子治疗回顾
公开(公告)号：EP2670485B1
公开(公告)日：2015-09-02
申请号：EP12702533.6
申请日：2012-02-03
申请人： ION BEAM APPLICATIONS S.A. , Université Libre de Bruxelles
发明人： PRIEELS, Damien , STICHELBAUT, Frédéric , SMEETS, Julien , DUBUS, Alain , DEHAES, Jean-Claude
IPC分类号： A61N5/10 , G01T1/164 , A61N5/00
CPC分类号： A61N5/1071 , A61N5/1048 , A61N5/1075 , A61N2005/1052 , A61N2005/1087 , F04C2270/041 , G01T1/2914

4. 发明公开

EP2977083A1 AN APPARATUS FOR PARTICLE THERAPY VERIFICATION 有权
标题翻译： VORRICHTUNG ZURPARTIKELTHERAPIEÜBERPRÜFUNG
公开(公告)号：EP2977083A1
公开(公告)日：2016-01-27
申请号：EP15181468.8
申请日：2012-02-03
申请人： ION BEAM APPLICATIONS S.A. , Université Libre de Bruxelles
发明人： PRIEELS, Damien , STICHELBAUT, Frédéric , SMEETS, Julien , DUBUS, Alain , DEHAES, Jean-Claude
IPC分类号： A61N5/10 , G01T1/164 , A61N5/00
CPC分类号： A61N5/1071 , A61N5/1048 , A61N5/1075 , A61N2005/1052 , A61N2005/1087 , F04C2270/041 , G01T1/2914
摘要： The invention is related to an apparatus and method for charged hadron therapy verification by detecting and/or quantifying prompt gammas produced when irradiating a target (6) with a charged hadron beam. The apparatus comprises a collimator (1) provided with a slit-shaped portion (2) configured to be arranged perpendicularly to the beam line and facing the target, a detection means (3,4) suitable for detecting said prompt gammas and a calculation and representation means. In the apparatus and method of the invention, the slit is configured to allow the passage of prompt gammas emitted from a range of depths in said target (6), said depths being measured in the direction of the charged hadron beam. Furthermore, said detection means is configured to detect prompt gammas emitted from each location within said range, and said calculation and representation means is configured to derive from a detected prompt gamma a value representative of the dose at the location from where said prompt gamma is emitted, and to represent a dose-related distribution for a plurality of locations within said range.
摘要翻译：本发明涉及一种用于通过检测和/或量化用带电荷的强子束照射目标（6）时产生的提示伽马的充电强子治疗验证的装置和方法。该装置包括准直器（1），该准直器（1）具有被配置为垂直于束线并且面向靶的狭缝状部分（2），适于检测所述提示伽马的检测装置（3,4）表示手段。在本发明的装置和方法中，狭缝构造成允许从所述目标（6）中的深度范围发射的快速伽马的通过，所述深度是在带电强子束的方向上测量的。此外，所述检测装置被配置为检测从所述范围内的每个位置发出的迅速的伽马值，并且所述计算和表示装置被配置为从检测到的提示gamma中导出代表在所述快速伽马发射的位置处的剂量的值并且表示在所述范围内的多个位置的剂量相关分布。

5. 发明申请

WO2012104416A1 AN APPARATUS FOR PARTICLE THERAPY VERIFICATION 审中-公开
标题翻译：用于颗粒治疗验证的装置
公开(公告)号：WO2012104416A1
公开(公告)日：2012-08-09
申请号：PCT/EP2012/051866
申请日：2012-02-03
申请人： ION BEAM APPLICATIONS S.A. , UNIVERSITE LIBRE DE BRUXELLES , PRIEELS, Damien , STICHELBAUT, Frédéric , SMEETS, Julien , DUBUS, Alain , DEHAES, Jean-Claude
发明人： PRIEELS, Damien , STICHELBAUT, Frédéric , SMEETS, Julien , DUBUS, Alain , DEHAES, Jean-Claude
IPC分类号： A61N5/10 , G01T1/164 , A61N5/00
CPC分类号： A61N5/1071 , A61N5/1048 , A61N5/1075 , A61N2005/1052 , A61N2005/1087 , F04C2270/041 , G01T1/2914
摘要： The invention is related to an apparatus and method for charged hadron therapy verification by detecting and/or quantifying prompt gammas produced when irradiating a target (6) with a charged hadron beam. The apparatus comprises a collimator (1) provided with a slit-shaped portion (2) configured to be arranged perpendicularly to the beam line and facing the target, a detection means (3,4) suitable for detecting said prompt gammas and a calculation and representation means. In the apparatus and method of the invention, the slit is configured to allow the passage of prompt gammas emitted from a range of depths in said target (6), said depths being measured in the direction of the charged hadron beam. Furthermore, said detection means is configured to detect prompt gammas emitted from each location within said range, and said calculation and representation means is configured to derive from a detected prompt gamma a value representative of the dose at the location from where said prompt gamma is emitted, and to represent a dose-related distribution for a plurality of locations within said range.
摘要翻译：本发明涉及一种用于通过检测和/或量化利用带电荷的强子束照射目标（6）时产生的提示性伽马的充电强子治疗验证的装置和方法。该装置包括准直器（1），该准直器（1）具有被配置为垂直于射束线且面向目标的狭缝状部分（2），适于检测所述快速伽马的检测装置（3,4）表示手段。在本发明的装置和方法中，狭缝被配置为允许从所述目标（6）中的深度范围发射的提示伽马射线的通过，所述深度在被充电的强子波束的方向上被测量。此外，所述检测装置被配置为检测从所述范围内的每个位置发出的迅速伽马值，并且所述计算和表示装置被配置为从检测到的提示gamma导出表示在所述快速伽马发射的位置处的剂量的值并且表示在所述范围内的多个位置的剂量相关分布。

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