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1. 发明申请

WO2006013329A1 ASSAY DEVICE & METHOD 审中-公开
标题翻译：测定装置和方法
公开(公告)号：WO2006013329A1
公开(公告)日：2006-02-09
申请号：PCT/GB2005/002927
申请日：2005-07-27
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , ZAK, Krzysztof, Wojciech , WILLIAMS, David
发明人： ZAK, Krzysztof, Wojciech , WILLIAMS, David
IPC分类号： G01N33/558
CPC分类号： G01N33/558 , G01N33/56944 , G01N2400/00 , G01N2469/10
摘要： There is disclosed a lateral flow assay device and method of producing the same. The device, which is for identifying carbohydrate antigens in a biological sample comprises a substrate having, a) a sample receiving zone, b) an extraction zone for receiving the sample from said sample receiving zone and which extraction zone comprises immobilised or otherwise absorbed therein at least one or more reactants and reagents which when combined react to form an extraction reagent for a desired antigen in said sample, said sample to be added to said sample receiving zone optionally comprising the remaining reactant required to form said extraction reagent if not present in said extraction zone, c) optionally a neutralising agent capable of bringing the pH of the resulting sample to within the operational pH range of the assay and, d) a detection zone for a labelled specific binding or capture reagent for said antigen to be detected.
摘要翻译：公开了一种侧流测定装置及其制造方法。用于在生物样品中鉴定碳水化合物抗原的装置包括具有a）样品接收区的底物，b）用于从所述样品接收区接收样品的提取区，并且该提取区包含固定或以其它方式被其中吸收的提取区当组合反应以形成所述样品中所需抗原的提取试剂时，所述至少一种或多种反应物和试剂，待添加到所述样品接收区的所述样品，任选地包含形成所述提取试剂所需的剩余反应物，如果不存在于所述提取区，c）任选的能够使得到的样品的pH达到测定操作pH范围内的中和剂，和d）用于待检测的所述抗原的标记的特异性结合或捕获试剂的检测区。

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