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    • 3. 发明申请
    • PARTICLE MANIPULATION AND TRAPPING IN MICROFLUIDIC DEVICES USING TWO-DIMENSIONAL MATERIAL
    • 用二维材料微流控装置中的粒子操纵和捕捉
    • WO2017175083A1
    • 2017-10-12
    • PCT/IB2017/051555
    • 2017-03-17
    • INTERNATIONAL BUSINESS MACHINES CORPORATIONIBM UNITED KINGDOM LIMITEDIBM (CHINA) INVESTMENT COMPANY LIMITED
    • AZPIROZ, Jaione, TirapuSTEINER, Mathias, BernhardENGEL, Michael
    • B01D57/02
    • Method, apparatus, and computer program product for a microfluidic channel having a cover opposite its bottom and having electrodes with patterned two-dimensional conducting materials, such as graphene sheets integrated into the top of its bottom. Using the two- dimensional conducting materials, once a fluid sample is applied into the channel, highly localized modulated electric field distributions are generated inside the channel and the fluid sample. This generated field causes the inducing of dielectrophoretic (DEP) forces. These DEP forces are the same or greater than DEP forces that would result using metallic electrodes because of the sharp edges enabled by the two-dimension geometry of the two- dimensional conducting materials. Because of the induced forces,micro/nano-particles in the fluid sample are separated into particles that respond to a negative DEP force and particles that respond to a positive DEP. Microfluidic chips with microfluidic channels can be made using standard semiconductor manufacturing technology.
    • 用于微流体通道的方法,装置和计算机程序产品具有与其底部相反的盖,并且具有带有图案化的二维导电材料的电极,例如集成在其底部顶部的石墨烯片。 使用二维导电材料,一旦将流体样品施加到通道中,就会在通道和流体样品内部产生高度局部化的调制电场分布。 这个产生的场导致介电泳(DEP)力的诱导。 这些DEP力与使用金属电极产生的DEP力相同或更大,这是因为二维导电材料的二维几何形状使得锐利的边缘成为可能。 由于诱导力,流体样品中的微/纳米颗粒被分离成响应负DEP力的颗粒和响应正DEP的颗粒。 具有微流体通道的微流控芯片可以使用标准的半导体制造技术制造。