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    • 2. 发明专利
    • DE60124653D1
    • 2007-01-04
    • DE60124653
    • 2001-09-28
    • INNOVADYNE TECHNOLOGIES INCUT BATTELLE LLC
    • JOHNSON JAMES EDIKTYCZ MITCHEL JPICHA NEIL R
    • F16K13/00B01J19/00B67D7/02C12M1/00C40B60/14G01N1/00G01N1/14G01N35/10G01N37/00
    • A manifold device for use with a valve assembly, an aspiration source and a dispensing source is described. The manifold body defines a plurality of fluid aspiration conduits each having an aspiration port in communication with an aspiration source, and a second aspiration port in selective fluid communication with a corresponding communication channel of the valve assembly to aspirate a respective liquid sample slug from a corresponding reservoir of sample fluid into discrete sample paths when the valve assembly is in the aspiration condition. The manifold body further defines a plurality of fluid dispensing conduits each having a first dispensing port in communication with the dispensing source, and a second dispensing port in selective fluid communication with a corresponding communication channel of the valve assembly to selectively dispense at least one droplet of the corresponding liquid sample slug from the corresponding sample path when the valve assembly is in the dispensing condition. In the aspiration condition, the sample paths are out of fluid communication with the dispensing source and in the dispensing condition the sample paths are out of fluid communication with the aspiration source.
    • 3. 发明专利
    • AT346256T
    • 2006-12-15
    • AT01308303
    • 2001-09-28
    • INNOVADYNE TECHNOLOGIES INCUT BATTELLE LLC
    • JOHNSON JAMES EDIKTYCZ MITCHEL JPICHA NEIL R
    • B01J19/00B67D7/02C12M1/00C40B60/14G01N1/00G01N1/14G01N35/10G01N37/00F16K13/00
    • A manifold device for use with a valve assembly, an aspiration source and a dispensing source is described. The manifold body defines a plurality of fluid aspiration conduits each having an aspiration port in communication with an aspiration source, and a second aspiration port in selective fluid communication with a corresponding communication channel of the valve assembly to aspirate a respective liquid sample slug from a corresponding reservoir of sample fluid into discrete sample paths when the valve assembly is in the aspiration condition. The manifold body further defines a plurality of fluid dispensing conduits each having a first dispensing port in communication with the dispensing source, and a second dispensing port in selective fluid communication with a corresponding communication channel of the valve assembly to selectively dispense at least one droplet of the corresponding liquid sample slug from the corresponding sample path when the valve assembly is in the dispensing condition. In the aspiration condition, the sample paths are out of fluid communication with the dispensing source and in the dispensing condition the sample paths are out of fluid communication with the aspiration source.
    • 4. 发明专利
    • HYBRID VALVE APPARATUS, SYSTEM AND METHOD FOR FLUID HANDLING
    • CA2358622C
    • 2011-02-08
    • CA2358622
    • 2001-10-09
    • INNOVADYNE TECHNOLOGIES INCUT BATTELLE LLC
    • JOHNSON JAMES EPICHA NEIL RDOKTYCZ MITCHEL J
    • G01N35/10B01J19/00B67D7/02C12M1/00C40B60/14G01N1/00G01N1/14G01N1/18G01N37/00
    • A hybrid valve apparatus for use with an aspiration actuator and a dispensing actuator to transfer fluid from a reservoir to a test site on a substrate surface. The hybrid valve includes a valve assembly movable between an aspiration condition and a dispensing condition, and a manifold device coupled to the valve assembly. The manifold device includes a fluid aspiration conduit having a first aspiration port in fluid communication with the aspiration actuator. On an opposite end of the aspiration conduit is a second aspiration port in selective fluid communication with the valve assembly to selectively aspirate a liquid sample slug from the reservoir into a discrete sample path when the valve assembly is in the aspiration condition. The manifold device further includes a fluid dispensing conduit having a first dispensing port in fluid communication with the dispensing actuator, and a second dispensing port in selective fluid communication with the valve assembly. When the valve assembly is in the dispensing condition, the sample path is fluidly coupled to the dispensing actuator to selectively dispense at least one droplet of the liquid sample slug therefrom, while simultaneously being out of fluid communication with the aspiration actuator. In contrast, in the aspiration condition, the sample path is in fluid communication with the aspiration actuator, while being out of fluid communication with the dispensing actuator.
    • 5. 发明专利
    • DE60124653T2
    • 2007-03-08
    • DE60124653
    • 2001-09-28
    • INNOVADYNE TECHNOLOGIES INCUT BATTELLE LLC
    • JOHNSON JAMES EDIKTYCZ MITCHEL JPICHA NEIL R
    • F16K13/00B01J19/00B67D7/02C12M1/00C40B60/14G01N1/00G01N1/14G01N35/10G01N37/00
    • A manifold device for use with a valve assembly, an aspiration source and a dispensing source is described. The manifold body defines a plurality of fluid aspiration conduits each having an aspiration port in communication with an aspiration source, and a second aspiration port in selective fluid communication with a corresponding communication channel of the valve assembly to aspirate a respective liquid sample slug from a corresponding reservoir of sample fluid into discrete sample paths when the valve assembly is in the aspiration condition. The manifold body further defines a plurality of fluid dispensing conduits each having a first dispensing port in communication with the dispensing source, and a second dispensing port in selective fluid communication with a corresponding communication channel of the valve assembly to selectively dispense at least one droplet of the corresponding liquid sample slug from the corresponding sample path when the valve assembly is in the dispensing condition. In the aspiration condition, the sample paths are out of fluid communication with the dispensing source and in the dispensing condition the sample paths are out of fluid communication with the aspiration source.
    • 6. 发明专利
    • HYBRID VALVE APPARATUS, SYSTEM AND METHOD FOR FLUID HANDLING
    • CA2358622A1
    • 2002-04-11
    • CA2358622
    • 2001-10-09
    • INNOVADYNE TECHNOLOGIES INCUT BATTELLE LLC
    • JOHNSON JAMES EDOKTYCZ MITCHEL JPICHA NEIL R
    • B01J19/00B67D7/02C12M1/00C40B60/14G01N1/00G01N1/14G01N35/10G01N37/00G01N1/18
    • A hybrid valve apparatus for use with an aspiration actuator and a dispensi ng actuator to transfer fluid from a reservoir to a test site on a substrate surface. The hybrid valve includes a valve assembly movable between an aspiratio n condition and a dispensing condition, and a manifold device coupled to the valve assembly. The manifold device includes a fluid aspiration conduit havi ng a first aspiration port in fluid communication with the aspiration actuator. On an opposite end of the aspiration conduit is a second aspiration port in selective fluid communication with the valve assembly to selectively aspirate a liquid sample slug from the reservoir into a discrete sample path when the valve assembly is in the aspiration condition. The manifold device further include s a fluid dispensing conduit having a first dispensing port in fluid communicati on with the dispensing actuator, and a second dispensing port in selective flui d communication with the valve assembly. When the valve assembly is in the dispensing condition, the sample path is fluidly coupled to the dispensing actuator to selectively dispense at least one droplet of the liquid sample slug therefrom, while simultaneously being out of fluid communication with the aspiration actuator. In contrast, in the aspiration condition, the sample pa th is in fluid communication with the aspiration actuator, while being out of flui d communication with the dispensing actuator.
    • 10. 发明专利
    • LOW VOLUME, NON-CONTACT LIQUID DISPENSING METHOD
    • CA2473860A1
    • 2003-08-07
    • CA2473860
    • 2003-01-27
    • INNOVADYNE TECHNOLOGIES INC
    • PICHA NEIL RJOHNSON JAMES ESTORMS CRAIG MMARTIN DAVID A
    • G01N37/00B01L3/02G01N35/00G01N35/10
    • An method for delivering repetitive, precision, low volume liquid dispensing from a dispensing orifice of a non-contact liquid dispensing apparatus. An elongated communication passageway of the dispensing apparatus is defined by interior walls having one end in fluid communication with a system fluid reservoir and an opposite end terminating at the dispensing orifice. A system fluid is placed in the communication passageway extending substantially continuously from the system fluid reservoir to the dispensing orifice. A relatively small volume of gaseous fluid is aspirated through the dispensing orifice, and into the communication passageway in a manner such that the gaseous fluid extends substantially continuously across the transverse cross- sectional dimension of the communication passageway. Subsequently, a dispensing liquid is aspirated through the dispensing orifice and into the communication passageway in a manner such that the relatively small volume of aspirated gaseous fluid forms a minute, unitary air gap fully enclosed between the interior walls of the communication passageway and a liquid interface between the system fluid and the dispensing liquid contained in the communication passageway. This minute air gap substantially prevents dispersion and dilution therebetween at the liquid interface. To effect dispensing, a rapid pressure pulse with a predetermined pulse width is applied to the system fluid upstream from the minute air gap, causing the pressure pulse to traverse the minute air gap to the dispensing liquid without substantial fluid compression of the minute air gap. This enables substantially accurate, relatively small volume, non-contact liquid dispensing of the dispensing liquid from the dispensing orifice.