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1. 发明授权

US11187360B2 Fluidic connector assembly for quick connect/disconnect 有权
公开(公告)号：US11187360B2
公开(公告)日：2021-11-30
申请号：US15617792
申请日：2017-06-08
申请人： IDEX Health & Science LLC
发明人： Eric Beemer , Scott Ellis , Craig Graham , Nathaniel Nienhuis , Troy Sanders
IPC分类号： F16L33/22 , G01N30/60 , F16L19/02 , F16L37/098 , B01L3/00 , F16L33/32
摘要： A fluidic connection assembly and methods for quickly connecting or disconnecting a tube to a port by hand and without the use of tools. A body is adapted to receive a tube therethrough, and may have at least two sides which are hinged. Each of the hinged sides has corresponding latching portions or projections located near a lower end of the body. These projections are adapted to fit into a port or other fitting and be securely held in place. The assembly may include a tube extending through a body and through a spring located between the end of the body and the end of the tube, whereby the spring exerts a force directly or indirectly against the end of the tube and against the body, thus holding the tubing securely and sealingly engaged in the port when the assembly is connected. The body may further comprise an additional body or an adapter, and/or a cap and latch. A second spring may be used to push a projecting member into a groove or notch of an adapter when an end of the adapter is inserted into one end of the latch or the body. The fluidic connection assembly is useful in analytical instrument systems, such as for in vitro applications and/or in high pressure applications, among other things, and may be used in methods for connecting, or disconnecting, tubing or a fluidic connection assembly from a port or other fitting or connection.

2. 发明授权

US09671048B2 Manifold connection assembly 有权
公开(公告)号：US09671048B2
公开(公告)日：2017-06-06
申请号：US15194289
申请日：2016-06-27
申请人： IDEX Health & Science LLC
发明人： Craig Graham , Eric Beemer , Scott Ellis , Troy Sanders , Carl Sims , Quan Liu , Nathaniel Nienhuis
IPC分类号： A61B10/00 , F16L15/08 , F16L19/02 , B01L3/00 , B01D15/14 , B01D15/16 , G01N30/60
CPC分类号： F16L15/08 , B01D15/14 , B01D15/163 , B01L3/563 , B01L2300/0838 , F16L19/0206 , F16L19/0212 , G01N30/32 , G01N30/6026 , G01N2030/328
摘要： A manifold assembly has a manifold and can be located between a block and a plate, and serve as a stator for a valve or other component. The manifold, block or plate can have a plurality of ports either integral thereto or removably connected thereto, with the ports adapted to receive and sealingly engage with a tube having an inner tube layer, an outer tube layer, a sleeve, a tip portion, and a nut. Each of the nut, sleeve, inner and outer tubing layers, and tip portion have a passageway therethrough, with at least the passageways in the sleeve, tip portion, outer tube layer, and nut adapted to allow the inner tube layer to pass therethrough or extend over the inner layer. The ends of the tip portion and inner layer together can define a substantially flat surface which can form a seal in a flat-bottomed port of the manifold, block, or plate, which can be used in a component in an analytical instrument system, including for example a liquid chromatography system. The nut, tube, ferrule, and transfer tube or liner tube may comprise biocompatible materials. In addition, the nut may have a slot, such as a slot adapted to allow the tube and the nut to be easily and quickly separated or to allow a portion of the tube to be easily and quickly inserted in the nut.

3. 发明授权

US09546985B2 Connection assembly for ultra high pressure liquid chromatography 有权
标题翻译：超高压液相色谱连接装置
公开(公告)号：US09546985B2
公开(公告)日：2017-01-17
申请号：US14038115
申请日：2013-09-26
申请人： IDEX Health & Science LLC
发明人： Scott J. Ellis , Eric Beemer , Nathaniel Nienhuis , Craig W. Graham , Troy N. Sanders
IPC分类号： G01N30/22 , G01N30/60 , F16L21/00
CPC分类号： G01N30/22 , F16L21/007 , G01N30/6026 , G01N30/6039 , Y10T29/49826
摘要： A fitting assembly having a nut, a ferrule, and a ferrule tip that may be assembled by an operator. The fitting assembly includes a nut with first and second ends, with the second end adapted to receive the first end of a ferrule, and a ferrule tip with a first end having an externally tapered portion adapted to abut the second end of the ferrule and a second end adapted to be received in a component or fitting of a liquid chromatography system. The nut, ferrule and ferrule tip of the fitting assembly have passageways therethrough for receiving and removably holding tubing.
摘要翻译：具有可由操作者组装的螺母，套圈和套圈末端的装配组件。配件组件包括具有第一和第二端的螺母，其第二端适于容纳套圈的第一端，以及具有第一端的套圈末端，该第一端具有适于邻接套圈的第二端的外锥形部分，第二端适于接收在液相色谱系统的组件或配件中。配件组件的螺母，套圈和套圈尖端具有穿过其的通道，用于接收和可移除地保持管道。

4. 发明申请

US20160116088A1 Face-Sealing Fluidic Connection System 审中-公开
标题翻译：面密封流体连接系统
公开(公告)号：US20160116088A1
公开(公告)日：2016-04-28
申请号：US14922041
申请日：2015-10-23
申请人： IDEX Health & Science LLC
发明人： Craig Graham , Eric Beemer , Scott Ellis , Troy Sanders , Nathaniel Nienhuis
IPC分类号： F16L15/08 , B01D15/10 , B01L3/00
CPC分类号： F16L15/08 , B01D15/10 , B01L3/563 , B01L2300/0838 , F16L19/0206 , F16L19/0212 , G01N30/6026
摘要： A tubing or fitting assembly has an inner tube layer, an outer tube layer, a sleeve, a tip portion, and can have a nut. Each of the nut, sleeve, inner and outer tubing layers, and tip portion have a passageway therethrough, with at least the passageways in the sleeve, tip portion, outer tube layer, and nut adapted to allow the inner tube layer to pass therethrough or extend over the inner layer. The tip portion can be molded over an end portion of the inner tube layer and also over a portion of the sleeve. The sleeve may include a retention feature in the form of a lip which extends into the tip portion, and also a narrower portion so that the tip portion and sleeve remain coupled together. The inner and outer tubing layers can also be retained by an interference fit. The ends of the tip portion and inner layer together define a substantially flat surface which can form a seal in a flat-bottomed port of a component such as may be found in any one of a number of components in an analytical instrument system, including for example a liquid chromatography system. The nut, tube, ferrule, and transfer tube or liner tube may comprise biocompatible materials. In addition, the nut may have a slot, such as a slot adapted to allow the tube and the nut to be easily and quickly separated or to allow a portion of the tube to be easily and quickly inserted in the nut.
摘要翻译：管或配件组件具有内管层，外管层，套管，末端部分，并且可以具有螺母。螺母，套筒，内管和外管层中的每个以及末端部分都具有通过其的通道，至少至少通过套管，顶端部分，外管层和适于允许内管层通过的通道，延伸到内层。尖端部分可以模制在内管层的端部上并且也可以在套筒的一部分上方模制。套筒可以包括延伸到尖端部分中的唇缘形式的保持部件，并且还包括较窄部分，使得尖端部分和套筒保持联接在一起。内外管层也可以通过过盈配合保持。尖端部分和内层的端部一起限定了基本上平坦的表面，该表面可以在诸如可以在分析仪器系统中的多个部件中的任何一个中找到的部件的平底端口中形成密封，包括用于例如液相色谱系统。螺母，管，套管和传送管或衬管可以包括生物相容性材料。此外，螺母可以具有狭槽，例如适于允许管和螺母容易且快速地分离的狭槽，或允许管的一部分容易且快速地插入螺母中。

5. 发明申请

US20200292108A1 Face-Sealing Fluidic Connection System 审中-公开
公开(公告)号：US20200292108A1
公开(公告)日：2020-09-17
申请号：US16856751
申请日：2020-04-23
申请人： IDEX Health & Science LLC
发明人： Craig Graham , Eric Beemer , Scott Ellis , Troy Sanders , Nathaniel Nienhuis
IPC分类号： F16L15/08 , F16L19/02 , G01N30/60 , B01D15/10 , B01L3/00
摘要： A tubing or fitting assembly has an inner tube layer, an outer tube layer, a sleeve, a tip portion, and can have a nut. Each of the nut, sleeve, inner and outer tubing layers, and tip portion have a passageway therethrough, with at least the passageways in the sleeve, tip portion, outer tube layer, and nut adapted to allow the inner tube layer to pass therethrough or extend over the inner layer. The tip portion can be molded over an end portion of the inner tube layer and also over a portion of the sleeve. The sleeve may include a retention feature in the form of a lip which extends into the tip portion, and also a narrower portion so that the tip portion and sleeve remain coupled together. The inner and outer tubing layers can also be retained by an interference fit. The ends of the tip portion and inner layer together define a substantially flat surface which can form a seal in a flat-bottomed port of a component such as may be found in any one of a number of components in an analytical instrument system, including for example a liquid chromatography system. The nut, tube, ferrule, and transfer tube or liner tube may comprise biocompatible materials. In addition, the nut may have a slot, such as a slot adapted to allow the tube and the nut to be easily and quickly separated or to allow a portion of the tube to be easily and quickly inserted in the nut.

6. 发明授权

US10655761B2 Face-sealing fluidic connection system 有权
公开(公告)号：US10655761B2
公开(公告)日：2020-05-19
申请号：US14922041
申请日：2015-10-23
申请人： IDEX Health & Science LLC
发明人： Craig Graham , Eric Beemer , Scott Ellis , Troy Sanders , Nathaniel Nienhuis
IPC分类号： F16L15/08 , F16L19/02 , G01N30/60 , B01D15/10 , B01L3/00
摘要： A tubing or fitting assembly has an inner tube layer, an outer tube layer, a sleeve, a tip portion, and can have a nut. Each of the nut, sleeve, inner and outer tubing layers, and tip portion have a passageway therethrough, with at least the passageways in the sleeve, tip portion, outer tube layer, and nut adapted to allow the inner tube layer to pass therethrough or extend over the inner layer. The tip portion can be molded over an end portion of the inner tube layer and also over a portion of the sleeve. The sleeve may include a retention feature in the form of a lip which extends into the tip portion, and also a narrower portion so that the tip portion and sleeve remain coupled together. The inner and outer tubing layers can also be retained by an interference fit. The ends of the tip portion and inner layer together define a substantially flat surface which can form a seal in a flat-bottomed port of a component such as may be found in any one of a number of components in an analytical instrument system, including for example a liquid chromatography system. The nut, tube, ferrule, and transfer tube or liner tube may comprise biocompatible materials. In addition, the nut may have a slot, such as a slot adapted to allow the tube and the nut to be easily and quickly separated or to allow a portion of the tube to be easily and quickly inserted in the nut.

7. 发明申请

US20170276275A1 Fluidic Connector Assembly for Quick Connect/Disconnect 审中-公开
公开(公告)号：US20170276275A1
公开(公告)日：2017-09-28
申请号：US15617792
申请日：2017-06-08
申请人： IDEX Health & Science LLC
发明人： Eric Beemer , Scott Ellis , Craig Graham , Nathaniel Nienhuis , Troy Sanders
IPC分类号： F16L33/22 , G01N30/60
CPC分类号： F16L33/227 , B01L3/563 , B01L2300/0838 , F16L19/0206 , F16L19/0212 , F16L33/32 , F16L37/0985 , G01N30/60
摘要： A fluidic connection assembly and methods for quickly connecting or disconnecting a tube to a port by hand and without the use of tools. A body is adapted to receive a tube therethrough, and may have at least two sides which are hinged. Each of the hinged sides has corresponding latching portions or projections located near a lower end of the body. These projections are adapted to fit into a port or other fitting and be securely held in place. The assembly may include a tube extending through a body and through a spring located between the end of the body and the end of the tube, whereby the spring exerts a force directly or indirectly against the end of the tube and against the body, thus holding the tubing securely and sealingly engaged in the port when the assembly is connected. The body may further comprise an additional body or an adapter, and/or a cap and latch. A second spring may be used to push a projecting member into a groove or notch of an adapter when an end of the adapter is inserted into one end of the latch or the body. The fluidic connection assembly is useful in analytical instrument systems, such as for in vitro applications and/or in high pressure applications, among other things, and may be used in methods for connecting, or disconnecting, tubing or a fluidic connection assembly from a port or other fitting or connection.

8. 发明授权

US11085904B2 Column having a compression-limited assembly 有权
公开(公告)号：US11085904B2
公开(公告)日：2021-08-10
申请号：US16146971
申请日：2018-09-28
申请人： IDEX Health & Science LLC
发明人： Daniel J. Czarnecki , Nathaniel Nienhuis , Eric Beemer , David Steckman , David Medeiros , Donald W. Pein
IPC分类号： G01N30/60 , G01N30/20 , G01N30/22 , G01N30/86 , G01N30/02
摘要： A chromatography column has a column assembly that further includes a column jacket tube and a column liner tube. The column assembly is configured with end fittings that have compression limiting features and are able to withstand very high pressure, such as used in UHPLC, in conjunction with flange portions of the column liner tube that seal the column assembly. The column liner tube may be biocompatible and may have a smooth consistent inner diameter of less than 2 mm, and an inner diameter of 1 mm in particular embodiments. The end fittings for the microtube assembly may ensure durability and reliability by preventing over- or under-tightening.

9. 发明授权

US10738918B2 Manifold connection assembly 有权
公开(公告)号：US10738918B2
公开(公告)日：2020-08-11
申请号：US15588408
申请日：2017-05-05
申请人： IDEX Health & Science LLC
发明人： Craig Graham , Eric Beemer , Scott Ellis , Troy Sanders , Carl Sims , Quan Liu , Nathaniel Nienhuis
IPC分类号： G01N1/00 , F16L15/08 , F16L19/02 , B01L3/00 , B01D15/14 , B01D15/16 , G01N30/32 , G01N30/60
摘要： A manifold assembly has a manifold and can be located between a block and a plate, and serve as a stator for a valve or other component. The manifold, block or plate can have a plurality of ports either integral thereto or removably connected thereto, with the ports adapted to receive and sealingly engage with a tube having an inner tube layer, an outer tube layer, a sleeve, a tip portion, and a nut. Each of the nut, sleeve, inner and outer tubing layers, and tip portion have a passageway therethrough, with at least the passageways in the sleeve, tip portion, outer tube layer, and nut adapted to allow the inner tube layer to pass therethrough or extend over the inner layer. The ends of the tip portion and inner layer together can define a substantially flat surface which can form a seal in a flat-bottomed port of the manifold, block, or plate, which can be used in a component in an analytical instrument system, including for example a liquid chromatography system. The nut, tube, ferrule, and transfer tube or liner tube may comprise biocompatible materials. In addition, the nut may have a slot, such as a slot adapted to allow the tube and the nut to be easily and quickly separated or to allow a portion of the tube to be easily and quickly inserted in the nut.

10. 发明申请

US20170268704A1 Manifold Connection Assembly 审中-公开
公开(公告)号：US20170268704A1
公开(公告)日：2017-09-21
申请号：US15588408
申请日：2017-05-05
申请人： IDEX Health & Science LLC
发明人： Craig Graham , Eric Beemer , Scott Ellis , Troy Sanders , Carl Sims , Quan Liu , Nathaniel Nienhuis
IPC分类号： F16L15/08 , B01L3/00 , B01D15/14 , B01D15/16 , F16L19/02 , G01N30/32
CPC分类号： F16L15/08 , B01D15/14 , B01D15/163 , B01L3/563 , B01L2300/0838 , F16L19/0206 , F16L19/0212 , G01N30/32 , G01N30/6026 , G01N2030/328
摘要： A manifold assembly has a manifold and can be located between a block and a plate, and serve as a stator for a valve or other component. The manifold, block or plate can have a plurality of ports either integral thereto or removably connected thereto, with the ports adapted to receive and sealingly engage with a tube having an inner tube layer, an outer tube layer, a sleeve, a tip portion, and a nut. Each of the nut, sleeve, inner and outer tubing layers, and tip portion have a passageway therethrough, with at least the passageways in the sleeve, tip portion, outer tube layer, and nut adapted to allow the inner tube layer to pass therethrough or extend over the inner layer. The ends of the tip portion and inner layer together can define a substantially flat surface which can form a seal in a flat-bottomed port of the manifold, block, or plate, which can be used in a component in an analytical instrument system, including for example a liquid chromatography system. The nut, tube, ferrule, and transfer tube or liner tube may comprise biocompatible materials. In addition, the nut may have a slot, such as a slot adapted to allow the tube and the nut to be easily and quickly separated or to allow a portion of the tube to be easily and quickly inserted in the nut.

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