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    • 6. 发明申请
    • Resistance-switching oxide thin film devices
    • 电阻切换氧化物薄膜器件
    • US20070120124A1
    • 2007-05-31
    • US11291945
    • 2005-11-30
    • I-Wei ChenYudi WangSoo Gil Kim
    • I-Wei ChenYudi WangSoo Gil Kim
    • H01L29/10
    • H01L29/0895H01L45/10H01L45/1233H01L45/1253H01L45/147H01L45/1625
    • Resistance-switching oxide films, and devices therewith, are disclosed. Resistance-switching oxide films, according to certain preferred aspects of the present invention, include at least about 75 atomic percent of an insulator oxide matrix having a conducting material dopant in an amount up to about 25 atomic percent. The matrix and dopant are preferably in solid solution. The insulator oxide matrix may also preferably include about 6 to about 12 atomic percent of a conducting material dopant. According to certain aspects of the present invention, the insulator oxide matrix, the conducting material dopant, or both, may have a perovskite crystal structure. The insulator oxide matrix may preferably include at least one of LaAlO3 and CaZrO3. Preferred conducting material dopants include SrRuO3, CaRuO3, or combinations thereof.
    • 公开了电阻切换氧化物膜及其装置。 根据本发明的某些优选方面的电阻切换氧化物膜包括至少约75原子%的具有高达约25原子百分比的导电材料掺杂剂的绝缘体氧化物基质。 基质和掺杂剂优选为固溶体。 绝缘体氧化物基质还可优选包括约6至约12原子%的导电材料掺杂剂。 根据本发明的某些方面,绝缘体氧化物基质,导电材料掺杂剂或两者可以具有钙钛矿晶体结构。 绝缘体氧化物基质可优选包括LaAlO 3和CaZ 3 O 3中的至少一种。 优选的导电材料掺杂剂包括SrR 3 O 3,Ca 3 O 3 3或其组合。
    • 7. 发明授权
    • Encapsulation of biomaterials in porous glass-like matrices prepared via an aqueous colloidal sol-gel process
    • 通过水性胶体溶胶 - 凝胶法制备的多孔玻璃样基质中生物材料的封装
    • US06303290B1
    • 2001-10-16
    • US09661122
    • 2000-09-13
    • Dean-Mo LiuI-Wei Chen
    • Dean-Mo LiuI-Wei Chen
    • C12Q100
    • C12N1/04C12N11/14G01N33/552
    • The present invention provides a process for the encapsulation of biologically important proteins into transparent, porous silica matrices by an alcohol-free, aqueous, colloidal sol-gel process, and to the biological materials encapsulated thereby. The process is exemplified by studies involving encapsulated cytochrome c, catalase, myoglobin, and hemoglobin, although non-proteinaceous biomaterials, such as active DNA or RNA fragments, cells or even tissues, may also be encapsulated in accordance with the present methods. Conformation, and hence activity of the biomaterial, is successfully retained after encapsulation as demonstrated by optical characterization of the molecules, even after long-term storage. The retained conformation of the biomaterial is strongly correlated to both the rate of gelation and the subsequent drying speed of the encapsulatng matrix. Moreover, in accordance with this process, gelation is accelerated by the use of a higher colloidal solid concentration and a lower synthesis pH than conventional methods, thereby enhancing structural stability and retained conformation of the biomaterials. Thus, the invention also provides a remarkable improvement in retaining the biological activity of the encapsulated biomaterial, as compared with those involved in conventional alkoxide-based processes. It further provides new methods for the quantitative and qualitative detection of test substances that are reactive to, or catalyzed by, the active, encapsulated biological materials.
    • 本发明提供了一种通过无醇,水性,胶体溶胶 - 凝胶方法将生物重要蛋白质包封到透明多孔二氧化硅基质中的方法,以及由其包封的生物材料。 尽管非蛋白质生物材料(例如活性DNA或RNA片段,细胞或甚至组织)也可以根据本发明的方法被包封,但该过程的例子涉及包封的细胞色素c,过氧化氢酶,肌红蛋白和血红蛋白。 构象,因此生物材料的活性,在封装后成功地保留,即使在长期储存后也通过分子的光学表征证实。 生物材料的保留构象与胶囊化的速率和随后的包封基质的干燥速度密切相关。 此外,根据该方法,通过使用比常规方法更高的胶体固体浓度和较低的合成pH来加速凝胶化,从而增强生物材料的结构稳定性和保留的构象。 因此,与常规的基于醇盐的方法相比,本发明还提供了保持包封的生物材料的生物活性的显着改进。 它进一步提供了用于定量和定性检测活性包封的生物材料反应或催化的测试物质的新方法。
    • 10. 发明授权
    • Resistance-switching memory based on semiconductor composition of perovskite conductor doped perovskite insulator
    • 基于钙钛矿导体掺杂钙钛矿绝缘体的半导体组成的电阻切换存储器
    • US08106375B2
    • 2012-01-31
    • US11291945
    • 2005-11-30
    • I-Wei ChenYudi WangSoo Gil Kim
    • I-Wei ChenYudi WangSoo Gil Kim
    • H01L45/00H01L27/24
    • H01L29/0895H01L45/10H01L45/1233H01L45/1253H01L45/147H01L45/1625
    • Resistance-switching oxide films, and devices therewith, are disclosed. Resistance-switching oxide films, according to certain preferred aspects of the present invention, include at least about 75 atomic percent of an insulator oxide matrix having a conducting material dopant in an amount up to about 25 atomic percent. The matrix and dopant are preferably in solid solution. The insulator oxide matrix may also preferably include about 6 to about 12 atomic percent of a conducting material dopant. According to certain aspects of the present invention, the insulator oxide matrix, the conducting material dopant, or both, may have a perovskite crystal structure. The insulator oxide matrix may preferably include at least one of LaAlO3 and CaZrO3. Preferred conducting material dopants include SrRuO3, CaRuO3, or combinations thereof.
    • 公开了电阻切换氧化物膜及其装置。 根据本发明的某些优选方面的电阻切换氧化物膜包括至少约75原子%的具有高达约25原子百分比的导电材料掺杂剂的绝缘体氧化物基质。 基质和掺杂剂优选为固溶体。 绝缘体氧化物基质还可优选包括约6至约12原子%的导电材料掺杂剂。 根据本发明的某些方面,绝缘体氧化物基质,导电材料掺杂剂或两者可以具有钙钛矿晶体结构。 绝缘体氧化物基质可以优选包括LaAlO 3和CaZrO 3中的至少一种。 优选的导电材料掺杂剂包括SrRuO 3,CaRuO 3或其组合。