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1. 发明专利

JP2008224270A Element for enzyme immunoassay and antigen-antibody reactor 审中-公开
标题翻译：酶免疫和抗原反应物的元素
公开(公告)号：JP2008224270A
公开(公告)日：2008-09-25
申请号：JP2007059624
申请日：2007-03-09
申请人： Hyogo Prefecture , 兵庫県
发明人： UCHIUMI YUICHI , NEGORO SEIJI , TAKEO MASAHIRO
IPC分类号： G01N33/543 , G01N33/553 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide an element for enzyme immunoassay capable of performing enzyme immunoassay more enhanced in sensitivity than before, and to provide an antigen-antibody reactor equipped with it. SOLUTION: The element for enzyme immunoassay has a large number of holes, which has flow channels therein, provided thereto by drilling and the flow channels are crossed to each other in the element. The element for enzyme immunoassay is constituted, by fixing a predetermined antibody or antigen to the surfaces of the inner walls of the flow channels. Furthermore, the antigen-antibody reactor is constituted by arranging a plurality of the elements for enzyme immunoassay on a plane. In this antigen-antibody reactor, the antibody or antigen fixed at each element for enzyme immunoassay may be different. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供能够进行酶免疫测定的酶免疫测定的元素比以前更灵敏地提高，并提供配备有抗原抗体的抗体反应器。解决方案：用于酶免疫测定的元件具有大量孔，其中具有流动通道，通过钻孔提供给它，并且流动通道在元件中彼此交叉。通过将预定的抗体或抗原固定在流动通道的内壁的表面上来构成酶免疫测定的要素。此外，抗原 - 抗体反应器通过在平面上排列多个用于酶免疫测定的元件来构成。在该抗原抗体反应器中，固定在每个元件上用于酶免疫测定的抗体或抗原可以不同。版权所有（C）2008，JPO＆INPIT

2. 发明专利

JP2008061501A Method for designing enzyme for catalyzing direct condensation reaction of free carboxylic acid amine, and method for enzymatically producing nylon oligomer 审中-公开
标题翻译：用于设计用于催化直接冷凝反应的游离羧酸胺的酶的方法和用于生产尼龙低聚物的方法
公开(公告)号：JP2008061501A
公开(公告)日：2008-03-21
申请号：JP2006239119
申请日：2006-09-04
申请人： Hyogo Prefecture , 兵庫県
发明人： NEGORO SEIJI , TAKEO MASAHIRO , KATO TAICHIRO , HIGUCHI YOSHIKI , SHIBATA NAOKI
IPC分类号： C12P13/00 , C12N9/00 , C12N9/86
CPC分类号： Y02P20/52
摘要： PROBLEM TO BE SOLVED: To provide an enzyme for catalyzing a direct condensation between a free carboxyl group and a free amino group, and to provide a method for enzymatically synthesizing a non-natural amide that uses such an enzyme. SOLUTION: A nylon oligomer is synthesized from 6-aminocaproic acid as the substrate, in the presence of a nylon oligomer-synthesizing enzyme having a specific sequence. This enzyme can catalyze direct condensation between a free carboxyl group and a free amino group under a mild condition of about 30°C, in a very short time and can synthesize nylon oligomer. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：待解决的问题：提供一种用于催化游离羧基和游离氨基之间的直接缩合的酶，并提供一种酶法合成使用这种酶的非天然酰胺的方法。解决方案：在具有特定序列的尼龙低聚物合成酶的存在下，由6-氨基己酸作为底物合成尼龙低聚物。该酶可以在非常短的时间内在约30℃的温和条件下催化游离羧基和游离氨基之间的直接缩合，并且可以合成尼龙低聚物。版权所有（C）2008，JPO＆INPIT

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