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    • 4. 发明授权
    • Sieving apparatus for a bio-chip
    • 用于生物芯片的筛分设备
    • US06320660B1
    • 2001-11-20
    • US09545954
    • 2000-04-10
    • Jau-Jiu JuDer-Ray HuangTzu-Ping Yang
    • Jau-Jiu JuDer-Ray HuangTzu-Ping Yang
    • G01N2125
    • G01N21/6452G01N21/251G01N2021/6478
    • The invention is directed to a sieving apparatus for a bio-chip, which has a light source, a HOE unit, a splitter, an objective lens, a filter, and an optical signal sensor. The HOE unit is coupled with a light source, so as to diffract the light into a zeroth order beam and a first order beam. The zeroth order beam has no deflection but the first order beam has a deflection from the zeroth order beam. The splitter is coupled to the HOE unit, so as to lead the two beams to the objective lens, which further leads the two beams to the bio-chip, in which the first order beam is incident onto the bio-chip from an incident angle, causing a florescent light from the sample. The bio-chip also reflects the zeroth order beam. Both the reflected zeroth order beam and the fluorescent light travel through the objective lens and the splitter. The filter is coupled to the splitter, so that an undesired portion of the light beams incident on the splitter is filtered. The optical sensor receives the light beams after the filter. The zeroth order beam is used to generate a focusing signal and a tracking signal. The focussing signal and the tracking signal are used to control the servo, so as to align the optical sensor to the samples for detecting the florescent light. Alternatively, the sensor can be fixed but the bio-chip is shifted by the servo system.
    • 本发明涉及一种用于生物芯片的筛分装置,其具有光源,HOE单元,分裂器,物镜,滤光器和光信号传感器。 HOE单元与光源耦合,以将光衍射成零级光束和一级光束。 零级光束没有偏转,但是第一级光束具有来自零级光束的偏转。 分离器耦合到HOE单元,以便将两个光束引导到物镜,该物镜进一步将两个光束引导到生物芯片,其中一阶光束从入射角入射到生物芯片上 ,引起来自样品的荧光。 生物芯片还反映了零级光束。 反射的零级光束和荧光都穿过物镜和分光镜。 滤波器耦合到分路器,使得入射在分路器上的不期望的部分光束被过滤。 光学传感器接收过滤器后的光束。 零级光束用于产生聚焦信号和跟踪信号。 聚焦信号和跟踪信号用于控制伺服,以便将光学传感器对准样品以检测荧光。 或者,传感器可以被固定,但是生物芯片被伺服系统移位。
    • 7. 发明授权
    • Dual-wavelength optical pickup head
    • 双波长光学拾音头
    • US06211511B1
    • 2001-04-03
    • US09227678
    • 1999-01-08
    • Hsi-Fu ShihTzu-Ping YangMark O. FreemanJinn-Kang Wang
    • Hsi-Fu ShihTzu-Ping YangMark O. FreemanJinn-Kang Wang
    • H10J4014
    • G11B7/1353G11B7/123G11B7/127G11B7/131G11B7/1356G11B7/1372G11B7/1381G11B7/139G11B2007/0006H01S5/02216H01S5/02292H01S5/02296H01S5/0683H01S5/4087
    • A dual-wavelength holographic laser module is provided. The dual-wavelength holographic laser module includes a holographic optical element (HOE), a multiple-element photodetector, and a laser light source that can produce a laser light with a wavelength that has, for example, two desired quantities. The laser light emitted from the laser light source with a desired wavelength can travel through the HOE and an objective lens unit, which is used to focus the laser light onto an optical disk of the DVD system, the CD system, or the CD-R system, depending on which wavelength quantity is chosen. The objective lens unit includes a single lens with a changeable NA quantity or a two-lens system that can be switched to put one lens at a time in the optical path. The optical disk reflects the laser light back to the HOE along the same light path. The reflected laser light is diffracted by the HOE to reach to the multiple-element photodetector. The photodetector receives the reflected laser light to obtain a signal, which is used for focusing and tracking, and further reads the information in the DVD system, the CD system, or the CD-R system. The laser light has a single light path even though the laser light can have two different wavelength quantities.
    • 提供双波长全息激光模块。 双波长全息激光器模块包括全息光学元件(HOE),多元件光电探测器和能产生具有例如两个所需量的波长的激光的激光光源。 从激光光源发射的具有所需波长的激光可以穿过HOE和物镜单元,该物镜单元用于将激光聚焦到DVD系统,CD系统或CD-R的光盘上 系统,取决于选择的波长数量。 物镜单元包括具有可变NA量的单透镜或双透镜系统,该双透镜系统可以在光路中一次将一个透镜切换。 光盘将激光沿相同的光路反射回HOE。 反射的激光被HOE衍射以到达多元件光电探测器。 光电检测器接收反射的激光以获得用于聚焦和跟踪的信号,并进一步读取DVD系统,CD系统或CD-R系统中的信息。 即使激光可以具有两个不同的波长数量,激光也具有单个光路。