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    • 3. 发明申请
    • Method and apparatus for classifying nucleic acid responses to infectious agents
    • 用于分类核酸对感染因子的反应的方法和装置
    • US20060183143A1
    • 2006-08-17
    • US11335982
    • 2006-01-20
    • Patrick LincolnSteven Eker
    • Patrick LincolnSteven Eker
    • C12Q1/68G06F19/00
    • G16B25/00G16B40/00
    • In one embodiment, the present invention is a method and apparatus for classifying nucleic acid responses to infectious agents. In one embodiment, a method for selecting genes to be analyzed to determine exposure to a condition (from among a plurality of potential conditions) includes determining, for each gene in a set of test data that includes genes and corresponding expression patterns for exposure to given conditions, a distance between each pair of conditions. A subset of genes from within the set of test data is then identified for which the distance between each pair of conditions is maximized. In this way, the number of genes whose expression patterns must be analyzed in order to reliably diagnose a condition is minimized.
    • 在一个实施方案中,本发明是用于分类核酸对感染因子的反应的方法和装置。 在一个实施方案中,用于选择要分析的基因以确定暴露于条件(从多个潜在条件中)的方法包括确定包含基因的一组测试数据中的每个基因和用于暴露于给定的相应表达模式 条件,每对条件之间的距离。 然后鉴定来自测试数据集合内的基因的子集,其中每对条件之间的距离最大化。 以这种方式,为了可靠地诊断病症而必须分析其表达模式的基因的数量被最小化。