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1. 发明申请

US20100256228A1 External Composition For Skin Containing Manassantin B as Active Ingredient and the Use Thereof For Skin Whitening 审中-公开
标题翻译：含有Manassantin B作为活性成分的皮肤外用组合物及其用于皮肤美白的用途
公开(公告)号：US20100256228A1
公开(公告)日：2010-10-07
申请号：US12515151
申请日：2007-11-02
申请人： Hui Kyoung Chang , Dae Gun Kim , Myeong Hoon Yeom , Hyun Jung Choi , Kyung Mi Joo , Jae Sung Hwang , Soo Mi Ahn
发明人： Hui Kyoung Chang , Dae Gun Kim , Myeong Hoon Yeom , Hyun Jung Choi , Kyung Mi Joo , Jae Sung Hwang , Soo Mi Ahn
IPC分类号： A61K8/49 , C07D407/12 , A61Q19/02
CPC分类号： A61K8/4973 , A61K31/343 , A61Q19/02
摘要： Disclosed herein are an external composition for skin, which contains, as an active ingredient, manassantin B extracted from Saururus chinensis Baill, and the use thereof for skin whitening. More particularly, disclosed are an external composition for skin, which contains, as an active ingredient, manassantin B, which inhibits the transfer of melanosomes, thus providing a skin-whitening effect without influencing the melanin synthesis function of the melanocytes, ad well as the use thereof for skin whitening.
摘要翻译：本发明公开了一种皮肤外用组合物，其含有作为活性成分的从中华黄ensis提取的马桑丁B及其用于皮肤美白的用途。更具体地，公开了一种皮肤外用组合物，其包含作为活性成分的抑制黑素体转移的马桑丁汀B，从而提供皮肤美白效果而不影响黑素细胞的黑色素合成功能，以及作为其用于皮肤美白。

2. 发明授权

US08258272B2 Agent for controlling Bcl-2 expression comprising ginsenoside F1 as an active component 有权
标题翻译：用于控制包含人参皂苷F1作为活性成分的Bcl-2表达的药剂
公开(公告)号：US08258272B2
公开(公告)日：2012-09-04
申请号：US12135663
申请日：2008-06-09
申请人： Si-Young Cho , Eun-Hee Lee , Su-Jung Kim , Eui-Seok Shin , Hui-Kyoung Chang , Duck-Hee Kim , Myeong Hoon Yeom , Kwang-Sik Woe , Tae-Ryong Lee , Young-Chul Sim
发明人： Si-Young Cho , Eun-Hee Lee , Su-Jung Kim , Eui-Seok Shin , Hui-Kyoung Chang , Duck-Hee Kim , Myeong Hoon Yeom , Kwang-Sik Woe , Tae-Ryong Lee , Young-Chul Sim
IPC分类号： A61K31/704 , A61P17/00 , C07J17/00
CPC分类号： A61K31/70
摘要： The present invention relates to an agent for controlling Bcl-2 expression comprising ginsenoside F1 (20-O-β-D-glucopyranosyl-20(S)-protopanaxatriol) represented by the following formula 1 as an active component.
摘要翻译：本发明涉及用于控制Bcl-2表达的试剂，其包含由下式1表示的活性成分的人参皂甙F1（20-O-＆bgr-D-吡喃葡萄糖基-20（S） - 原人参三醇）。

3. 发明授权

US08173607B2 Promoter for the production of hyaluronic acid containing ginsenoside compound K 有权
标题翻译：用于生产含有人参皂苷化合物K的透明质酸的启动子
公开(公告)号：US08173607B2
公开(公告)日：2012-05-08
申请号：US12184622
申请日：2008-08-01
申请人： Su-Jong Kim , Byung-Young Kang , Si-Young Cho , Hui-Kyoung Chang , Dae-Seok Sung , Myeong Hoon Yeom , Kwang-Sik Woe , Duck-Hee Kim , Han-Kon Kim , Young-Chul Sim , Hak-Hee Kang , Yong-Sung Lee
发明人： Su-Jong Kim , Byung-Young Kang , Si-Young Cho , Hui-Kyoung Chang , Dae-Seok Sung , Myeong Hoon Yeom , Kwang-Sik Woe , Duck-Hee Kim , Han-Kon Kim , Young-Chul Sim , Hak-Hee Kang , Yong-Sung Lee
IPC分类号： A61K31/704 , A61K31/70
CPC分类号： A61K31/704 , A61K8/735 , A61Q19/08
摘要： There are provided a promoter containing ginsenoside compound K for the production of hyaluronic acid, and more particularly, a new efficacy of 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (compound K), a chief metabolite of ginseng saponin, to increase the expression of hyaluronic acid synthase gene in human cell and thereby to promote the production of hyaluronic acid, and an anti-aging agent containing the promoter for the production of hyaluronic acid as an effective ingredient.
摘要翻译：提供了含有人参皂甙化合物K用于制备透明质酸的促进剂，更具体地说，涉及20-O-和D-吡喃葡萄糖基-20（S） - 原人参二醇（化合物K）的新功效，人参皂苷，以增加人细胞中透明质酸合酶基因的表达，从而促进透明质酸的生成，以及含有用于生产透明质酸作为有效成分的促进剂的抗老化剂。

4. 发明授权

US08263565B2 Nanoemulsion comprising metabolites of ginseng saponin as an active component and a method for preparing the same, and a skin-care composition for anti-aging containing the same 有权
标题翻译：包含作为活性成分的人参皂甙代谢物的纳米乳剂及其制备方法，以及含有其的抗衰老护肤组合物
公开(公告)号：US08263565B2
公开(公告)日：2012-09-11
申请号：US11443271
申请日：2006-05-31
申请人： Byung Hee Yoo , Byung Young Kang , Myeong Hoon Yeom , Dae Seok Sung , Sang Hoon Han , Han Kon Kim , Hee Kyung Ju
发明人： Byung Hee Yoo , Byung Young Kang , Myeong Hoon Yeom , Dae Seok Sung , Sang Hoon Han , Han Kon Kim , Hee Kyung Ju
IPC分类号： A01N43/04 , A01N65/00 , A61K31/70 , A61K36/254 , A61K36/258
CPC分类号： B82Y5/00 , A61K8/06 , A61K8/068 , A61K8/63 , A61K8/97 , A61K2800/21 , A61K2800/413 , A61Q19/08
摘要： Disclosed herein is nanoemulsion prepared by emulsifying main metabolites of ginseng saponin obtained by conversion of glucose, i.e. compound K (20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol), ginsenoside F1 (20-O-β-D-glucopyranosyl-20(S)-protopanaxatriol) and compound Y (20-O-[α-L-arabinopyranosyl(1→6)-β-D-glucopyranosyl]-20(S)-protopanaxadiol); and admixture thereof, in fine emulsion or liposome with dermotropic emulsifier by nano-emulsification; and having enhanced skin penetration, so to be effective in promoting proliferation of fibroblast and biosynthesis of collagen.
摘要翻译：本文公开了通过乳化葡萄糖转化获得的人参皂苷的主要代谢物即化合物K（20-O-和b-D-吡喃葡萄糖基-20（S） - 原人参二醇），人参皂苷F1（20-O- -D-吡喃葡萄糖基-20（S） - 原人参三醇）和化合物Y（20-O- [α-L-阿拉伯吡喃糖基（1→6） - ＆amp; D-吡喃葡萄糖基] -20（S） - 原人参二醇）; 并通过纳米乳化法在细乳液或脂质体中与透皮乳化剂混合; 并具有增强的皮肤渗透性，从而有效促进成纤维细胞的增殖和胶原的生物合成。

5. 发明申请

US20100297270A1 COMPOSITION FOR TREATMENT OF ISCHEMIC HEART DISEASE, FACILITATION OF BLOOD CIRCULATION AND ANGIOGENESIS, IMPROVING SKIN BEAUTY, IMPROVING MALE SEXUAL FUNCTION CONTAINING GINSENG BERRY EXTRACT 审中-公开
标题翻译：用于治疗异位心脏疾病的组合物，促进血液循环和血管生成，改善皮肤美白，改善含有金山百利提取物的男性功能
公开(公告)号：US20100297270A1
公开(公告)日：2010-11-25
申请号：US12602457
申请日：2008-05-28
申请人： Chan-Woong Park , Myeong Hoon Yeom , Nam Hoon Cho , Sang Jun Lee , Sang Min Lee , Jin Young Lee , Hee Yong Jeon , Young-Myeong Kim , Chun-Ki kim , Young Deuk Choi
发明人： Chan-Woong Park , Myeong Hoon Yeom , Nam Hoon Cho , Sang Jun Lee , Sang Min Lee , Jin Young Lee , Hee Yong Jeon , Young-Myeong Kim , Chun-Ki kim , Young Deuk Choi
IPC分类号： A61K36/258 , A61K8/97 , A61Q19/08 , A61Q19/02 , A61Q19/00 , A61P9/00 , A61P9/10 , A61P15/10 , A61P15/00
CPC分类号： A61K36/258 , A23L33/105 , A23V2002/00 , A61K9/0019 , A61K9/0095 , A61K9/1652 , A61K9/2018 , A61K9/4875 , A61K31/198 , A23V2250/2124 , A23V2200/318 , A23V2200/326 , A61K2300/00
摘要： A composition containing ginseng berry extract as active ingredient is for facilitation of blood circulation, for prevention of vascular aging, for treatment of vascular inflammation, for facilitation of angiogenesis, for treatment of ischemic heart disease, for improvement and treatment of local blood circulation insufficiency, for improvement of skin beauty and for improvement of male sexual function. More particularly, the compositions containing ginseng berry extract as active ingredient facilitate nitric oxide (NO) generation in endothelial cells, improve viability of endothelial cells, and facilitate angiogenesis through increased mobility of endothelial cells and vascular tube formation; provide antioxidative effect, facilitate biosynthesis of collagen, provide skin aging inhibiting and wrinkle improving effects through inhibition of MMP-1, provide skin whitening effect through inhibition of melanin synthesis, and provide skin moisturizing effect; and improve male sexual function through relaxation of the corpus cavernosum and enhancement of penial erection, and, as used in combination with l-arginine, which is a substrate of nitric oxide synthase, provide synergically enhanced NO generation.
摘要翻译：含有人参浆果提取物作为活性成分的组合物用于促进血液循环，用于预防血管衰老，治疗血管发炎，促进血管生成，治疗缺血性心脏病，改善和治疗局部血液循环功能不全，用于改善皮肤美容和改善男性性功能。更特别地，含有人参浆果提取物作为活性成分的组合物促进内皮细胞中的一氧化氮（NO）产生，改善内皮细胞的活力，并通过增加内皮细胞的活动性和血管形成促进血管生成; 提供抗氧化作用，促进胶原蛋白的生物合成，通过抑制MMP-1提供皮肤衰老抑制和皱纹改善作用，通过抑制黑色素合成提供皮肤美白效果，并提供皮肤保湿效果; 并通过放松海绵体和增强阴茎勃起来改善男性的性功能，并且与作为一氧化氮合成酶底物的1-精氨酸组合使用可提供协同增强的NO产生。

6. 发明申请

US20080280335A1 Manufacturing Method of Kaempferol 审中-公开
标题翻译：山奈酚的制备方法
公开(公告)号：US20080280335A1
公开(公告)日：2008-11-13
申请号：US11795343
申请日：2005-05-30
申请人： Myeong Hoon Yeom , Jun-seong Park , Won-Seok Park , Kyungmi Joo , Ho Sik Rho , Duck Hee Kim , Ih Seop Jang , Ok-Sub Lee
发明人： Myeong Hoon Yeom , Jun-seong Park , Won-Seok Park , Kyungmi Joo , Ho Sik Rho , Duck Hee Kim , Ih Seop Jang , Ok-Sub Lee
IPC分类号： C12P17/06 , C07D311/04
CPC分类号： C12P17/06
摘要： Disclosed is a kaempferol preparing method comprising isolating kaempferol from kaempferol glucosides using an acid, a base, an enzyme or a microbe producing the enzyme. More specifically, the method comprises obtaining a plant extract containing kaempferol glycosides from a plant using water or an organic solvent; and hydrolyzing the plant extract using an acid, a base, an enzyme or a microbe producing the enzyme to isolate kaempferol. The kaempferol glycosides comprise camelliaside A or camelliaside B. The plant extract is derived from a seed or leaf of green tea. When using the method of the invention, it is possible to mass-produce kaempferol, which is one of main physiological activating ingredients, from a plant, particularly a seed or leaf of green tea.
摘要翻译：公开了一种山奈酚的制备方法，其包括使用产生该酶的酸，碱，酶或微生物从山奈酚糖苷中分离山奈酚。更具体地，该方法包括使用水或有机溶剂从植物获得含有山奈酚苷的植物提取物; 并使用产生该酶的酸，碱，酶或微生物水解植物提取物以分离山奈酚。山奈酮糖苷含有山茶花A或山茶花B。植物提取物衍生自绿茶的种子或叶子。当使用本发明的方法时，可以从植物，特别是绿茶的种子或叶中大量生产作为主要生理活性成分之一的山奈酚。

7. 发明申请

US20100189821A1 COMPOSITION OF SKIN EXTERNAL APPLICATION CONTAINING GINSENG BERRY EXTRACTS 有权
标题翻译：含金山莓提取物的皮肤外用剂组合物
公开(公告)号：US20100189821A1
公开(公告)日：2010-07-29
申请号：US12602421
申请日：2008-05-30
申请人： Chan Woong Park , Myeong Hoon Yeom , Jin Young Lee , Hee Young Jeon , Sang Jun Lee , Nam Hoon Cho , Dong Sung Lee
发明人： Chan Woong Park , Myeong Hoon Yeom , Jin Young Lee , Hee Young Jeon , Sang Jun Lee , Nam Hoon Cho , Dong Sung Lee
IPC分类号： A61K8/97 , A61Q19/08 , A61K36/254 , A61P29/00 , A61P17/10
CPC分类号： A23L1/3002 , A23L33/105 , A23V2002/00 , A61K8/97 , A61K36/258 , A61K2800/522 , A61Q19/02 , A61Q19/08 , A23V2250/2124 , A23V2200/318 , A23V2200/332
摘要： Disclosed herein is a. skin external composition containing ginseng berry extract. More specifically, disclosed is a skin external composition, which contains, as an active ingredient, ginseng berry extract having the specific components and compositions, among the above-ground parts of ginseng, and thus promotes the production of collagen in the skin, shows an MMP-I inhibitory effect and, at the same time, has skin-aging inhibitory and wrinkle-reducing effects, resulting from antioxidant effects and DNA damage-protecting effects. Also disclosed is a skin external composition, which contains, as an active ingredient, ginseng berry extract, which has a skin whitening effect resulting from the effects of inhibiting melanin production and reducing pigmentation caused by UV radiation, the effects of relieving dry skin symptoms and atopic symptoms by inducing and maintaining the normal differentiation of skin keratinocytes, the effect of relieving acne and skin troubles by the regulation of sebum secretion and an anti-inflammatory effect, and makes complexion ruddy through the improvement of peripheral blood circulation to make the skin clean and clear. Also disclosed is a food composition for reducing and preventing obesity, which contains, as an active ingredient, ginseng berry extract, which increases the expression of a carnitine palmitoyl transterase-1 (CPT-I) gene, serves to transport fatty acids into mitochondria in fatty acid oxidation and promotes fat oxidation.
摘要翻译：本文公开的是皮肤外用组合物含人参浆果提取物。更具体地，公开了皮肤外用组合物，其含有人参的地上部分中具有特定成分和组成的人参浆果提取物作为活性成分，从而促进皮肤中的胶原蛋白的生成，显示出 MMP-1抑制作用，同时具有由抗氧化作用和DNA损伤保护作用产生的皮肤衰老抑制和皱纹减轻作用。还公开了一种皮肤外用组合物，其含有作为活性成分的人参浆果提取物，其具有由抑制黑色素产生和减少由紫外线辐射引起的色素沉着的作用而产生的皮肤美白效果，减轻干性皮肤症状的效果和通过诱导和维持皮肤角质形成细胞的正常分化，减轻痤疮和皮肤麻烦的作用，通过调节皮脂分泌和抗炎作用而产生特应性症状，并通过改善外周血液循环使肤色变红，使皮肤清洁并清楚还公开了用于减少和预防肥胖的食物组合物，其包含增加肉碱棕榈酰转铁蛋白-1（CPT-1）基因表达的人参浆果提取物作为活性成分，用于将脂肪酸运输到线粒体中脂肪酸氧化并促进脂肪氧化。

8. 发明申请

US20080280838A1 Composition Containing Ginsenoside F1 and Egcg for Preventing Skin Damage 审中-公开
标题翻译：含有人参皂苷F1和Egcg以防止皮肤损伤的组合物
公开(公告)号：US20080280838A1
公开(公告)日：2008-11-13
申请号：US10599290
申请日：2004-06-01
申请人： Si Young Cho , Byung Young Kang , Myeong Hoon Yeom , Tae Ryong Lee , Ih Seop Chang
发明人： Si Young Cho , Byung Young Kang , Myeong Hoon Yeom , Tae Ryong Lee , Ih Seop Chang
IPC分类号： A61K31/7032 , A61Q19/00
CPC分类号： A61K8/63 , A61K8/046 , A61K8/347 , A61K2800/59 , A61Q17/04 , A61Q19/00 , A61Q19/08
摘要： The present invention relates to a skin-care composition containing ginsenoside F1 and EGCG. More particularly, the present invention relates to an inhibitor of UV-induced apoptosis in epidermal cells showing an excellent skin-care effect by the synergistic interaction of the said ginsenoside F1 and EGCG even at low concentrations, and to a method for inhibiting apoptosis in epidermal cells.
摘要翻译：本发明涉及含有人参皂苷F1和EGCG的护肤组合物。更具体地说，本发明涉及在表皮细胞中UV诱导的细胞凋亡的抑制剂，即使在低浓度下也表现出与所述人参皂甙F1和EGCG的协同相互作用的极好的护肤效果，以及抑制表皮细胞凋亡的方法细胞。

9. 发明授权

US11066814B2 Two-layer vanity or sink unit 有权
公开(公告)号：US11066814B2
公开(公告)日：2021-07-20
申请号：US16880986
申请日：2020-05-22
申请人： Myeong Hoon Yeom
发明人： Myeong Hoon Yeom
IPC分类号： E03C1/01 , E03C1/02 , E03C1/182
摘要： Disclosed herein is a two-layer vanity unit. The two-layer vanity unit includes: a cabinet; an upper vanity unit disposed on a top of the cabinet and exposed to the outside; a lower vanity unit disposed inside the cabinet so that it is selectively put into the cabinet when not in use and withdrawn from the cabinet when in use; drain pipes connected to the upper and lower vanity units; and cold and hot water pipes connected to the upper vanity unit. Control is performed to adjust one or more of water supply and water cutoff for the upper or lower vanity unit and an amount and temperature of the available water according to an operation mode of the lever of the faucet provided on the upper or lower vanity unit, thereby controlling a type of supply of available water.

10. 发明授权

US09314493B2 Method for treating vascular inflammation, improving skin beauty and improving male sexual function using ginseng berry 有权
标题翻译：使用人参浆果治疗血管炎症，改善皮肤美容和改善男性性功能的方法
公开(公告)号：US09314493B2
公开(公告)日：2016-04-19
申请号：US13565224
申请日：2012-08-02
申请人： Chan-Woong Park , Myeong Hoon Yeom , Nam Hoon Cho , Sang Jun Lee , Sang Min Lee , Jin Young Lee , HeeYong Jeon , Young-Myeong Kim , Chun-Ki Kim , Young Deuk Choi
发明人： Chan-Woong Park , Myeong Hoon Yeom , Nam Hoon Cho , Sang Jun Lee , Sang Min Lee , Jin Young Lee , HeeYong Jeon , Young-Myeong Kim , Chun-Ki Kim , Young Deuk Choi
IPC分类号： A61K36/258 , A61Q19/08 , A61K8/97 , A61K31/198 , A61Q19/02
CPC分类号： A61K36/258 , A61K8/97 , A61K31/198 , A61Q19/02 , A61Q19/08 , A61K2300/00
摘要： The present disclosure discloses a method for treating vascular inflammation, improving skin beauty and improving male sexual function of a subject by administering a ginseng berry extract to the subject.
摘要翻译：本公开公开了一种通过向受试者施用人参浆果提取物来治疗血管炎症，改善皮肤美容并改善受试者的男性性功能的方法。

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