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1. 发明申请

US20060257903A1 Compositions and methods for diagnosing and treating neuropsychiatric disorders 有权
标题翻译：用于诊断和治疗神经精神障碍的组合物和方法
公开(公告)号：US20060257903A1
公开(公告)日：2006-11-16
申请号：US11396050
申请日：2006-03-31
申请人： Huda Akil , Mary Atz , William Bunney , William Byerley , Kathleen Casey , Prabhakara Choudary , Simon Evans , Edward Jones , Jun Li , Juan Lopez , Richard Myers , Brandi Rollins , Robert Thompson , Hiroaki Tomita , Marquis Vawter , Stanley Watson
发明人： Huda Akil , Mary Atz , William Bunney , William Byerley , Kathleen Casey , Prabhakara Choudary , Simon Evans , Edward Jones , Jun Li , Juan Lopez , Richard Myers , Brandi Rollins , Robert Thompson , Hiroaki Tomita , Marquis Vawter , Stanley Watson
IPC分类号： C12Q1/68 , G01N33/567
CPC分类号： G01N33/6893 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/573 , G01N33/6896 , G01N2500/00 , G01N2500/04 , G01N2800/28 , G01N2800/30 , G01N2800/302 , G01N2800/304
摘要： The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia and mood disorders such as major depression disorder and bipolar disorder). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
摘要翻译：本发明提供了用于诊断精神障碍（例如精神病性障碍如精神分裂症和情绪障碍如重性抑郁障碍和双相情感障碍）的方法。本发明还提供鉴定这种精神障碍的调节剂的方法以及使用这些调节剂来治疗患有这种精神障碍的患者的方法。

2. 发明申请

US20050209181A1 Compositions and methods for diagnosing and treating mental disorders 审中-公开
标题翻译：精神障碍诊断和治疗的组成和方法
公开(公告)号：US20050209181A1
公开(公告)日：2005-09-22
申请号：US10982556
申请日：2004-11-04
申请人： Huda Akil , Mary Atz , William Bunney , Prabhakara Choudary , Simon Evans , Edward Jones , Jun Li , Juan Lopez , Richard Myers , Robert Thompson , Hiroaki Tomita , Marquis Vawter , Stanley Watson
发明人： Huda Akil , Mary Atz , William Bunney , Prabhakara Choudary , Simon Evans , Edward Jones , Jun Li , Juan Lopez , Richard Myers , Robert Thompson , Hiroaki Tomita , Marquis Vawter , Stanley Watson
IPC分类号： A61B20060101 , A61K31/519 , A61K48/00 , C12Q1/68
CPC分类号： A61K31/519 , A61K31/7088 , G01N33/6893 , G01N2800/30 , G01N2800/302
摘要： The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.
摘要翻译：本发明提供了用于诊断精神障碍（例如精神病性精神障碍如精神分裂症）的方法。本发明还提供鉴定这种精神障碍的调节剂的方法以及使用这些调节剂来治疗患有这种精神障碍的患者的方法。

3. 发明申请

US20060051786A1 Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder 有权
标题翻译：在双相障碍和/或重度抑郁障碍中差异表达的基因和途径
公开(公告)号：US20060051786A1
公开(公告)日：2006-03-09
申请号：US11158530
申请日：2005-06-21
申请人： Huda Akil , William Bunney , Prabhakara Choudary , Simon Evans , Edward Jones , Jun Li , Juan Lopez , David Lyons , Margherita Molnar , Richard Myers , Alan Schatzberg , Richard Stein , Robert Thompson , Hiroaki Tomita , Marquis Vawter , Stanley Watson
发明人： Huda Akil , William Bunney , Prabhakara Choudary , Simon Evans , Edward Jones , Jun Li , Juan Lopez , David Lyons , Margherita Molnar , Richard Myers , Alan Schatzberg , Richard Stein , Robert Thompson , Hiroaki Tomita , Marquis Vawter , Stanley Watson
IPC分类号： C12Q1/68 , G01N33/53
CPC分类号： C12Q1/6883 , A61K31/713 , A61K38/1825 , C07K16/22 , C12N15/1136 , C12N2310/14 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172 , G01N33/6896 , G01N33/74 , G01N2333/726 , G01N2800/304
摘要： The present invention provides methods for diagnosing mental disorders. The invention also provides methods of identifying modulators of mental disorders as well as methods of using these modulators to treat patients suffering from mental disorders.
摘要翻译：本发明提供了诊断精神障碍的方法。本发明还提供识别精神障碍调节剂的方法以及使用这些调节剂治疗患有精神障碍的患者的方法。

4. 发明申请

US20090019557A1 FGF2-RELATED METHODS FOR DIAGNOSING AND TREATING DEPRESSION 审中-公开
公开(公告)号：US20090019557A1
公开(公告)日：2009-01-15
申请号：US11559398
申请日：2006-11-13
申请人： Huda Akil , Stanley Watson , Simon Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
发明人： Huda Akil , Stanley Watson , Simon Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
IPC分类号： A01K67/00 , C12Q1/68 , C12Q1/02 , G01N33/68 , A61K38/17
CPC分类号： C12Q1/6883 , A61K38/03 , A61K38/10 , A61K38/1774 , A61K38/1825 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , G01N33/5023 , G01N2800/304
摘要： The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.

5. 发明申请

US20080199866A1 SNP DETECTION AND OTHER METHODS FOR CHARACTERIZING AND TREATING BIPOLAR DISORDER AND OTHER AILMENTS 审中-公开
标题翻译：表征和处理双极性疾病及其他物质的SNP检测及其他方法
公开(公告)号：US20080199866A1
公开(公告)日：2008-08-21
申请号：US11868456
申请日：2007-10-05
申请人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara V. Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher
发明人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William Bunney , Marquis Vawter , Edward Jones , Prabhakara V. Choudary , Richard Myers , Alan Schatzberg , Jun Li , Devin Absher
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： The present application relates to the use of SNPs and differential exon expression to characterize, diagnose or treat bipolar disorder and other mental illnesses, such as major depressive disorder and schizophrenia.
摘要翻译：本申请涉及使用SNP和差异外显子表达来表征，诊断或治疗双相情感障碍和其他精神疾病，如重度抑郁障碍和精神分裂症。

6. 发明申请

US20120277159A1 METHODS FOR TREATING DEPRESSION USING NCAM PEPTIDE MIMETICS 有权
标题翻译：使用NCAM肽模拟物治疗呕吐的方法
公开(公告)号：US20120277159A1
公开(公告)日：2012-11-01
申请号：US13431893
申请日：2012-03-27
申请人： Huda Akil , Stanley Watson , Cortney Turner , William Bunney , Edward Jones , Richard Myers , Alan Schatzberg
发明人： Huda Akil , Stanley Watson , Cortney Turner , William Bunney , Edward Jones , Richard Myers , Alan Schatzberg
IPC分类号： A61K38/10 , A61P25/24
CPC分类号： C12Q1/6883 , A61K38/03 , A61K38/10 , A61K38/1774 , A61K38/1825 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , G01N33/5023 , G01N2800/304
摘要： The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.
摘要翻译：本申请涉及心理障碍的治疗和诊断，包括双相情感障碍，重症抑郁障碍和精神分裂症。本发明提供了新的诊断标记和测定，以及用于开发和发现可用于治疗患有精神疾病的患者的药剂和化合物的研究工具。

7. 发明授权

US06697792B2 Method for distributing information 有权
标题翻译：分发信息的方法
公开(公告)号：US06697792B2
公开(公告)日：2004-02-24
申请号：US09557171
申请日：2000-04-21
申请人： William Bunney , Tetsuya Kozo
发明人： William Bunney , Tetsuya Kozo
IPC分类号： G06F700
CPC分类号： G06F17/30867 , Y10S707/99931 , Y10S707/99945 , Y10S707/99952
摘要： A system for distributing information comprises at least one content source (2, 3), at least one client (4, 5), a communication network (6), a distribution server (1), a profile data base (10) associated with the distribution server (1) in which client profile information is stored, and a target count unit (9) in the distribution server (10) for effecting a target count by comparing the client profile information of the profile data base (10) with target client information of a target count request sent from one of the content sources (2, 3). Information from one of the content sources (2, 3) is distributed to at least one client (4, 5) by means of the distribution server (1) corresponding to the result of the target count effected by the target count unit (9).
摘要翻译：用于分发信息的系统包括至少一个内容源（2,3），至少一个客户端（4,5），通信网络（6），分发服务器（1），与...相关联的简档数据库（10）其中存储有客户端简档信息的分发服务器（1）和分发服务器（10）中的目标计数单元（9），用于通过将简档数据库（10）的客户机简档信息与目标从一个内容源（2,3）发送的目标计数请求的客户端信息。来自一个内容源（2,3）的信息通过与由目标计数单元（9）进行的目标计数的结果对应的分发服务器（1）分发给至少一个客户端（4,5）。

8. 发明授权

US6003032A Data communication system 失效
标题翻译：数据通信系统
公开(公告)号：US6003032A
公开(公告)日：1999-12-14
申请号：US989314
申请日：1997-12-12
申请人： William Bunney , Kozo Tetsuya
发明人： William Bunney , Kozo Tetsuya
IPC分类号： G06F12/00 , G06F13/00 , G06F17/30 , H04L29/06
CPC分类号： G06F17/3089 , H04L67/42 , Y10S707/915 , Y10S707/917 , Y10S707/99945
摘要： A server computer for a data communication system and adapted to transmit a document via a network, such as the Internet or an intranet, to a client computer in response to a request. The server includes an article memory for storing a plurality of article documents and respective bibliographic data; processing circuitry for receiving from a system administrator and storing an article document selection rule, and for retrieving from the article memory a subset of the plurality of article documents and assembling a table of contents-type document from at least part of each of the subset of article documents. The subset of article documents is selected according to the respective bibliographic data using the article document selection rule. Transmission circuitry is responsive to the request for transmitting the assembled document onto the network for delivery to the client computer.
摘要翻译：一种用于数据通信系统的服务器计算机，用于响应于请求，经由诸如因特网或内联网的网络将文档传送到客户端计算机。服务器包括用于存储多个物品文件和各自的书目数据的物品存储器; 处理电路，用于从系统管理员接收并存储文章文档选择规则，并且用于从所述文章存储器检索所述多个文章文档的子集，并且从所述多个文章文档的每个子集的至少一部分组装内容类型文档表文章文件。使用文章文件选择规则，根据各自的书目数据选择文章文档的子集。传输电路响应于将组装的文档发送到网络上以将其传送到客户端计算机的请求。

9. 发明授权

US06487584B1 Multiple personality internet account 失效
标题翻译：多重个性网络账户
公开(公告)号：US06487584B1
公开(公告)日：2002-11-26
申请号：US09270600
申请日：1999-03-17
申请人： William Bunney
发明人： William Bunney
IPC分类号： G06F1516
CPC分类号： H04L51/28 , H04L29/06 , H04L29/12009 , H04L29/12047 , H04L29/12594 , H04L51/043 , H04L61/15 , H04L61/30 , H04L67/14 , H04L67/306 , H04L69/329
摘要： According to the present invention a communication method and a communication system/network is provided comprising at least one server and a plurality of user terminals. Wherein the user terminals can share information with each other and with the at least one server by means of the internet each user can be accessed by means of a unique address. Thereby a plurality of different unique addresses can be assigned to one user. A corresponding assignment information is stored in a table of the server. The assignment information enables the server to associate a plurality of different addresses for the same user. Respectively one profile can be associated to one of the plurality of addresses assigned to one user, the profiles containing characteristics of the preferences and/or interests of the associated address and being stored in a database of a profile manager. Respectively one home page can be created and associated to one of the plurality of addresses assigned to one user, the home pages being stored on the server. The server furthermore can comprise a group database containing different predefined groups, preferences and/or interests of each group as well as the user addresses which are members of the corresponding group.
摘要翻译：根据本发明，提供了包括至少一个服务器和多个用户终端的通信方法和通信系统/网络。其中用户终端可以通过互联网彼此共享信息和与至少一个服务器共享信息，每个用户可以通过唯一的地址来访问。因此，可以向一个用户分配多个不同的唯一地址。相应的分配信息存储在服务器的表中。分配信息使得服务器能够将相同用户的多个不同的地址相关联。分别可以将一个配置文件与分配给一个用户的多个地址中的一个相关联，该配置文件包含相关地址的偏好和/或兴趣的特征并存储在配置文件管理器的数据库中。可以分别创建一个主页并将其分配给分配给一个用户的多个地址之一，主页被存储在服务器上。此外，服务器还可以包括包含不同的预定义组，每个组的偏好和/或兴趣以及作为相应组的成员的用户地址的组数据库。

10. 发明授权

US06564217B2 Data communication system that transmits the selected contents and menu onto the network for delivery to the client computer 有权
标题翻译：将所选择的内容和菜单发送到网络上以传送到客户端计算机的数据通信系统
公开(公告)号：US06564217B2
公开(公告)日：2003-05-13
申请号：US09418916
申请日：1999-10-15
申请人： William Bunney , Kozo Tetsuya
发明人： William Bunney , Kozo Tetsuya
IPC分类号： G06F1730
CPC分类号： G06F17/3089 , H04L67/42 , Y10S707/915 , Y10S707/917 , Y10S707/99945
摘要： A server computer for a data communication system and adapted to transmit a document via a network, such as the Internet or an intranet, to a client computer in response to a request therefrom. The server includes an article memory for storing a plurality of article documents and respective bibliographic data; processing circuitry for receiving from a system administrator and storing an article document selection rule, and for retrieving from the article memory a subset of the plurality of article documents and assembling a table of contents-type document from at least part of each of the subset of article documents. The subset of article documents is selected according to the respective bibliographic data using the article document selection rule. Transmission circuitry is responsive to the request for transmitting the assembled document onto the network for delivery to the client computer.
摘要翻译：一种用于数据通信系统的服务器计算机，并且适于经由诸如因特网或内联网的网络将文档经由响应于该请求的请求发送到客户端计算机。服务器包括用于存储多个物品文件和各自的书目数据的物品存储器; 处理电路，用于从系统管理员接收并存储文章文档选择规则，并且用于从所述文章存储器检索所述多个文章文档的子集，并且从所述多个文章文档的每个子集的至少一部分组装内容类型文档表文章文件。使用文章文件选择规则，根据各自的书目数据选择文章文档的子集。传输电路响应于将组装的文档发送到网络上以将其传送到客户端计算机的请求。

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