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1. 发明授权

US08217670B2 Label-free sensor 有权
标题翻译：无标签传感器
公开(公告)号：US08217670B2
公开(公告)日：2012-07-10
申请号：US12500689
申请日：2009-07-10
申请人： Hsin-Fei Meng , Sheng-Fu Hong , Yu-Chiang Chao , Chien-Cheng Liu , Wen-Hsing Liu , Cheng-Chung Chang , Jan-Hao Li , Ming-Zhi Dai
发明人： Hsin-Fei Meng , Sheng-Fu Hong , Yu-Chiang Chao , Chien-Cheng Liu , Wen-Hsing Liu , Cheng-Chung Chang , Jan-Hao Li , Ming-Zhi Dai
IPC分类号： G01R27/08
CPC分类号： G01N33/5438 , G01N27/4145
摘要： The invention provides a label-free sensor that includes a substrate, a first electrode formed on the substrate, a second electrode formed on the substrate and spaced away from the first electrode, and a semiconductor layer formed on the substrate and being in contact with the first electrode and the second electrode. The semiconductor layer has a plurality of probe groups bonded to the semiconductor layer by functionalization, for sensing a coupling-specific substance having bonding specificity with the probe groups. The semiconductor layer is bonded with the probe groups, and the detection of detected object is performed in an instant, quick, rapid, and sensitive manner by measuring variation in electric current, avoiding the use of fluorescent reading equipment for reading fluorescent signals.
摘要翻译：本发明提供了一种无标签传感器，其包括基板，形成在基板上的第一电极，形成在基板上并与第一电极间隔开的第二电极，以及形成在基板上并与基板接触的半导体层第一电极和第二电极。半导体层具有多个通过官能化键合到半导体层的探针组，用于感测与探针组具有键合特异性的偶联特异性物质。半导体层与探针组结合，通过测量电流的变化，以瞬时，快速，快速和敏感的方式进行检测对象的检测，避免使用荧光读取设备读取荧光信号。

2. 发明申请

US20100237885A1 LABEL-FREE SENSOR 有权
标题翻译：无标签传感器
公开(公告)号：US20100237885A1
公开(公告)日：2010-09-23
申请号：US12500689
申请日：2009-07-10
申请人： Hsin- Fei Meng , Sheng-Fu Hong , Yu-Chiang Chao , Chien-Cheng Liu , Wen-Hsing Liu , Cheng-Chung Chang , Jan-Hao Li , Ming-Zhi Dai
发明人： Hsin- Fei Meng , Sheng-Fu Hong , Yu-Chiang Chao , Chien-Cheng Liu , Wen-Hsing Liu , Cheng-Chung Chang , Jan-Hao Li , Ming-Zhi Dai
IPC分类号： G01R19/00 , H01L29/12 , H01L51/30
CPC分类号： G01N33/5438 , G01N27/4145
摘要： A label-free sensor is disclosed. The label-free sensor comprises a substrate, a first electrode formed on the substrate, a second electrode formed on the substrate and spaced away from the first electrode, and a semiconductor layer formed on the substrate and is in contact with the first electrode and the second electrode, wherein the semiconductor layer has a plurality of probe groups, which are bonded to the semiconductor layer by functionalization, for sensing a coupling-specific substance, which has bonding specificity with the probe groups. The semiconductor layer of the label-free sensor of the present invention is bonded with probe groups, and the detection of detected object is performed in instant, quick, rapid, and sensitive manner by measuring variation in electric current, thereby avoiding the use of the fluorescent reading equipment for reading fluorescent signals.
摘要翻译：公开了一种无标签传感器。无标记传感器包括基板，形成在基板上的第一电极，形成在基板上并与第一电极隔开的第二电极，以及形成在基板上并与第一电极和第二电极接触的半导体层第二电极，其中半导体层具有多个探针组，其通过官能化键合到半导体层，用于感测与探针组具有键合特异性的偶联特异性物质。本发明的无标签传感器的半导体层与探针组接合，通过测量电流的变化，以即时，快速，快速，敏感的方式进行检测对象的检测，从而避免使用用于读取荧光信号的荧光阅读设备。

3. 外观设计

USD681111S1 Note sheets and related pads of note sheets 有权
公开(公告)号：USD681111S1
公开(公告)日：2013-04-30
申请号：US29418050
申请日：2012-04-11
申请人： Jay K. Sato , Eric Kim , Susan L. Broyles , Darren S. Ferris , Cheng-Chung Chang , Tsun-Rung Hsu
设计人： Jay K. Sato , Eric Kim , Susan L. Broyles , Darren S. Ferris , Cheng-Chung Chang , Tsun-Rung Hsu

4. 外观设计

USD681110S1 Note sheets and related pads of note sheets 有权
标题翻译：笔记本和笔记本的相关垫
公开(公告)号：USD681110S1
公开(公告)日：2013-04-30
申请号：US29412793
申请日：2012-02-07
申请人： Jay K. Sato , Eric Kim , Susan L. Broyles , Darren S. Ferris , Cheng-Chung Chang , Tsun-Rung Hsu
设计人： Jay K. Sato , Eric Kim , Susan L. Broyles , Darren S. Ferris , Cheng-Chung Chang , Tsun-Rung Hsu

5. 外观设计

USD667494S1 Note sheets and related pads of note sheets 有权
标题翻译：笔记本和笔记本的相关垫
公开(公告)号：USD667494S1
公开(公告)日：2012-09-18
申请号：US29418047
申请日：2012-04-11
申请人： Jay K. Sato , Eric Kim , Susan L. Broyles , Darren S. Ferris , Cheng-Chung Chang , Tsun-Rung Hsu
设计人： Jay K. Sato , Eric Kim , Susan L. Broyles , Darren S. Ferris , Cheng-Chung Chang , Tsun-Rung Hsu

6. 发明申请

US20110111429A1 FLUORESCENT CARBAZOLE COMPOUNDS FOR CANCER DIAGNOSIS 有权
标题翻译：用于癌症诊断的荧光卡博唑化合物
公开(公告)号：US20110111429A1
公开(公告)日：2011-05-12
申请号：US12613770
申请日：2009-11-06
申请人： Ta-Chau Chang , Chih-Chien Cho , Cheng-Chung Chang , Chi-Chih Kang , Zi-Fu Wang
发明人： Ta-Chau Chang , Chih-Chien Cho , Cheng-Chung Chang , Chi-Chih Kang , Zi-Fu Wang
IPC分类号： G01N33/53 , C07D211/68
CPC分类号： C07D401/14 , C09K11/06 , C09K2211/1029
摘要： A compound of formula (I): in which R1-R8, A, B, X, Y, m, and n are as defined herein. Also disclosed is a method for detecting a cancer cell using a compound of formula I.
摘要翻译：式（I）化合物：其中R 1 -R 8，A，B，X，Y，m和n如本文所定义。还公开了使用式I化合物检测癌细胞的方法。

7. 发明授权

US07691624B2 Cancer cell detecting devices 有权
标题翻译：癌细胞检测装置
公开(公告)号：US07691624B2
公开(公告)日：2010-04-06
申请号：US11582867
申请日：2006-10-18
申请人： Ta-Chau Chang , Cheng-Chung Chang , Chi-Chih Kang , Ji-Yen Cheng
发明人： Ta-Chau Chang , Cheng-Chung Chang , Chi-Chih Kang , Ji-Yen Cheng
IPC分类号： C12M1/34 , C12M3/00
CPC分类号： G01N21/6428
摘要： This invention relates to a device for detecting cancer cells. The device includes a light source for generating light (e.g., a light emitting diode), a first optical filter selected from the group consisting of a band pass filter and a long pass filter, a second optical filter (i.e., a band pass filter) disposed between the light source and the first optical filter, and a sample receiver for receiving a sample. The sample receiver is disposed between the first and second optical filters. The first optical filter, the sample receiver, and the second optical filter are aligned so that light emitted from the light source passes sequentially through the second optical filter, the sample receiver, and the first optical filter.
摘要翻译：本发明涉及一种用于检测癌细胞的装置。该装置包括用于产生光的光源（例如，发光二极管），从由带通滤波器和长通滤波器组成的组中选择的第一滤光器，第二滤光器（即，带通滤光器）设置在光源和第一滤光器之间，以及用于接收样品的样品接收器。样品接收器设置在第一和第二滤光器之间。对准第一滤光器，样品接收器和第二滤光器，使得从光源发射的光顺序地通过第二滤光器，样品接收器和第一滤光器。

8. 发明申请

US20060171109A1 External drive cabinet 失效
标题翻译：外部驱动器柜
公开(公告)号：US20060171109A1
公开(公告)日：2006-08-03
申请号：US11093213
申请日：2005-03-29
申请人： Cheng-Chung Chang
发明人： Cheng-Chung Chang
IPC分类号： G06F1/16
CPC分类号： G11B33/122 , G06F1/184 , G06F1/187 , G11B25/043 , G11B33/022 , G11B33/124
摘要： An external drive cabinet is provided. The present invention is unique in that and a power connector and a data interface connector installed on the back side of the cabinet frame are not on the same level but positioned in step manner, keeping a buffer space in between. Such arrangement of connectors enables one of the two connectors to make connection before the other does, thus smoothing out the plugging and unplugging processes. The tray is equipped with hinge joint at the rear end that is able to swing the front end of the tray upward when the handle bar is pulled up. The front panel of the hard disk can be completely concealed in the drive cabinet, as against the exposed the conventional drive cabinet with the front panel exposed.
摘要翻译：提供外部驱动器柜。本发明是独特的，并且安装在机柜框架背面的电源连接器和数据接口连接器不在同一水平上，而是以分步方式定位，保持缓冲空间。这种连接器的布置使得两个连接器之一能够在另一个连接器之前进行连接，从而平滑插拔和拔出过程。托盘在后端装有铰链接头，当把手拉起时，可以向上摆动托盘的前端。硬盘的前面板可以完全隐藏在驱动器柜中，防止暴露在前面板暴露的传统驱动器柜中。

9. 外观设计

USD460070S1 Portable keyboard 失效
标题翻译：便携式键盘
公开(公告)号：USD460070S1
公开(公告)日：2002-07-09
申请号：US29145063
申请日：2001-07-17
申请人： Cheng-Chung Chang
设计人： Cheng-Chung Chang

10. 外观设计

USD690351S1 Note sheets and related pads of note sheets 有权
公开(公告)号：USD690351S1
公开(公告)日：2013-09-24
申请号：US29412791
申请日：2012-02-07
申请人： Jay K. Sato , Eric Kim , Susan L. Broyles , Darren S. Ferris , Cheng-Chung Chang , Tsun-Rung Hsu
设计人： Jay K. Sato , Eric Kim , Susan L. Broyles , Darren S. Ferris , Cheng-Chung Chang , Tsun-Rung Hsu

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