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1. 发明授权

US09566323B2 Vaccine for cervical cancer 有权
标题翻译：子宫颈癌疫苗
公开(公告)号：US09566323B2
公开(公告)日：2017-02-14
申请号：US13379212
申请日：2009-10-20
申请人： Hong-Jin Kim , Na Gyong Lee , Yang-Je Cho , Jin-Wook Jang , Hyoung Jin Kim , Kwang Sung Kim
发明人： Hong-Jin Kim , Na Gyong Lee , Yang-Je Cho , Jin-Wook Jang , Hyoung Jin Kim , Kwang Sung Kim
IPC分类号： A61K39/12 , A61K39/39 , A61K39/00
CPC分类号： A61K39/12 , A61K39/39 , A61K2039/5258 , A61K2039/55505 , A61K2039/55572 , A61K2039/70 , C12N2710/20023 , C12N2710/20034
摘要： The present invention relates to a pharmaceutical vaccine composition for a human cervical cancer, comprising: (a) (i) a L1 virus-like particle (VLP) of human papillomavirus (HPV) type 16, a L1 VLP of HPV type 18, or a combination thereof; and (ii) a deacylated non-toxic lipooligosaccharide (LOS); and (b) a pharmaceutically acceptable carrier; and a method for preparing a human papillomavirus (HPV) L1 virus-like particle (VLP). The pharmaceutical vaccine composition of the present invention is in both Th1-type immune response (cellular immunity) and Th2-type immune response (humoral immunity) against HPV more excellent than Cervrix™ and Gardasil™, exhibiting a superior efficacy as a vaccine for a human cervical cancer.
摘要翻译：本发明涉及用于人宫颈癌的药物疫苗组合物，其包括：（i）（i）16型人乳头状瘤病毒（HPV）的L1病毒样颗粒（VLP），HPV 18型的L1 VLP或其组合; 和（ii）脱酰无毒低密度寡糖（LOS）; 和（b）药学上可接受的载体; 以及制备人乳头状瘤病毒（HPV）L1病毒样颗粒（VLP）的方法。本发明的药物疫苗组合物具有比Cervrix TM和Gardasil TM更优异的Th1型免疫应答（细胞免疫）和对HPV的Th2型免疫应答（体液免疫），表现出作为疫苗的优异功效人宫颈癌。

2. 发明申请

US20120100169A1 Vaccine for Cervical Cancer 有权
标题翻译：疫苗用于宫颈癌
公开(公告)号：US20120100169A1
公开(公告)日：2012-04-26
申请号：US13379212
申请日：2009-10-20
申请人： Hong-Jin Kim , Na Gyong Lee , Yang-Je Cho , Jin-Wook Jang , Hyoung Jin Kim , Kwang Sung Kim
发明人： Hong-Jin Kim , Na Gyong Lee , Yang-Je Cho , Jin-Wook Jang , Hyoung Jin Kim , Kwang Sung Kim
IPC分类号： A61K39/12 , A61P35/00 , C12N1/19 , A61P37/04 , C12P21/02 , C12N15/37
CPC分类号： A61K39/12 , A61K39/39 , A61K2039/5258 , A61K2039/55505 , A61K2039/55572 , A61K2039/70 , C12N2710/20023 , C12N2710/20034
摘要： The present invention relates to a pharmaceutical vaccine composition for a human cervical cancer, comprising: (a) (i) a L1 virus-like particle (VLP) of human papillomavirus (HPV) type 16, a L1 VLP of HPV type 18, or a combination thereof; and (ii) a deacylated non-toxic lipooligosaccharide (LOS); and (b) a pharmaceutically acceptable carrier; and a method for preparing a human papillomavirus (HPV) L1 virus-like particle (VLP). The pharmaceutical vaccine composition of the present invention is in both Th1-type immune response (cellular immunity) and Th2-type immune response (humoral immunity) against HPV more excellent than Cervrix™ and Gardasil™, exhibiting a superior efficacy as a vaccine for a human cervical cancer.
摘要翻译：本发明涉及用于人宫颈癌的药物疫苗组合物，其包括：（i）（i）16型人乳头状瘤病毒（HPV）的L1病毒样颗粒（VLP），HPV 18型的L1 VLP或其组合; 和（ii）脱酰无毒低密度寡糖（LOS）; 和（b）药学上可接受的载体; 以及制备人乳头状瘤病毒（HPV）L1病毒样颗粒（VLP）的方法。本发明的药物疫苗组合物具有比Cervrix TM和Gardasil TM更优异的Th1型免疫应答（细胞免疫）和对HPV的Th2型免疫应答（体液免疫），表现出作为疫苗的优异功效人宫颈癌。

3. 发明授权

US06549251B2 LCD having barrier layer in same plane as gate electrode and method of fabricating 有权
标题翻译： LCD具有与栅电极相同的平面中的阻挡层和制造方法
公开(公告)号：US06549251B2
公开(公告)日：2003-04-15
申请号：US09891230
申请日：2001-06-26
申请人： Hong-Jin Kim
发明人： Hong-Jin Kim
IPC分类号： G02F1136
CPC分类号： G02F1/1368 , G02F2201/123
摘要： An array substrate for a liquid crystal display device, the array substrate including a substrate, a gate line including a gate electrode disposed upon the substrate, a data line disposed upon the substrate and formed orthogonal to the gate line, a barrier disposed upon the substrate and spaced apart from the gate electrode and the data line, a gate insulating layer disposed upon the substrate to cover the gate line, the gate electrode, and the barrier, an active layer disposed upon the gate insulating layer and over the gate electrode, a source electrode disposed upon the active layer, a drain electrode having a first portion disposed upon the active layer opposite to the source electrode, and a second portion disposed upon the insulating layer to cross over the barrier, a pixel region defined by a cross of the gate line and the data line, and a pixel electrode electrically connected to the second portion of the drain electrode.
摘要翻译：一种液晶显示装置用阵列基板，具有基板的阵列基板，配置在基板上的栅电极的栅极线，配置在基板上并形成为与栅极线正交的数据线，设置在基板上的阻挡层并且与栅电极和数据线间隔开，栅极绝缘层设置在衬底上以覆盖栅极线，栅极电极和栅极，设置在栅极绝缘层上和栅极上的有源层，设置在有源层上的源电极，具有设置在与源电极相对的有源层上的第一部分的漏电极和设置在绝缘层上以越过势垒的第二部分，栅极线和数据线，以及电连接到漏电极的第二部分的像素电极。

4. 发明授权

US07136760B2 Visualization method of RNA pseudoknot structures 有权
公开(公告)号：US07136760B2
公开(公告)日：2006-11-14
申请号：US10170251
申请日：2002-06-11
申请人： Kyungsook Han , Wootaek Kim , Yujin Lee , Hong-Jin Kim
发明人： Kyungsook Han , Wootaek Kim , Yujin Lee , Hong-Jin Kim
IPC分类号： G06F7/00 , G01N33/48 , C12Q1/68 , G06G7/48
CPC分类号： G06F19/26 , G06F19/16 , Y10S707/99943
摘要： Disclosed is a visualization method of RNA pseudoknot structures. The method of the invention comprises the steps of setting criteria required for visualizing RNA pseudoknots, setting structural elements and data structures for representing a whole RNA structure containing pseudoknots, determining an input format for visualization and a drawing order of the structure, determining connectivity relations between regular loops and stems in the structure and between pseudoknot loops and stems in the structure, calculating radii of the regular loop and the PK loop, calculating coordinates of bases in the regular loops, setting internal angles of the PK loops, calculating startAngles of the regular loops and angles of the stem, determining positions of the pseudoknots in the PK loops, and drawing the pseudoknots and the whole RNA structure containing the pseudoknots.

5. 发明申请

US20050089849A1 Expression vector containing urea cycle enzyme gene, transformant thereof, and use of transformant for protein over-expression 有权
标题翻译：含有尿素循环酶基因的表达载体，其转化体，以及转化体用于蛋白质过表达的用途
公开(公告)号：US20050089849A1
公开(公告)日：2005-04-28
申请号：US10363421
申请日：2001-08-24
申请人： Hong-Jin Kim , Myung-Il Chung , Ik-Hwan Kim , Ick-Young Kim
发明人： Hong-Jin Kim , Myung-Il Chung , Ik-Hwan Kim , Ick-Young Kim
IPC分类号： C12N9/10 , C12P21/00 , C12Q1/68 , C07H21/04 , C12N5/06 , C12N9/80 , C12P21/02
CPC分类号： C12N9/1018 , C12P21/00
摘要： The present invention relates to expression vectors containing in vivo urea cycle enzyme gene; transformants thereof; and the use of transformants for protein overexpression. During the overexpression of protein, if the animal cell transformed with expression vectors of the present invention is used, amounts of ammonia accumulation within cell culture medium will decrease and cell growth rate will increase, thus, it is advantageous to be capable of obtaining desired protein in high yields.
摘要翻译：本发明涉及含有体内尿素循环酶基因的表达载体; 转化体并使用转化体进行蛋白质过表达。在蛋白质的过表达中，如果使用本发明的表达载体转化的动物细胞，则细胞培养液中的氨积累量会降低，细胞生长速度增加，因此有利的是获得所需的蛋白质产量高。

6. 发明授权

US06645558B2 Method for forming molecular layers having high density of primary amine group on solid supports 失效
标题翻译：在固体载体上形成具有高密度伯胺基团的分子层的方法
公开(公告)号：US06645558B2
公开(公告)日：2003-11-11
申请号：US10239389
申请日：2002-11-18
申请人： Joon-Won Park , Hong-Jin Kim
发明人： Joon-Won Park , Hong-Jin Kim
IPC分类号： B05D136
CPC分类号： C08G83/005
摘要： Provided is a method for forming solid substrates having high density of primary amine group on its surface, in which the primary amine groups on the surface of an aminosilylated substrate are treated with aziridine or an aziridine derivative. The surface density of the primary amine functional groups (—NH2) on the very top surface of a substrate can be drastically increased.
摘要翻译：提供了在其表面上形成具有高密度伯胺基团的固体基质的方法，其中氨基硅烷化基底物的伯胺基被氮丙啶或氮丙啶衍生物处理。在基底的最上表面上的伯胺官能团（-NH 2）的表面密度可以大大增加。

7. 发明申请

US20120083189A1 CHEMICAL MECHANICAL POLISHING APPARATUS HAVING PAD CONDITIONING DISK AND PRE-CONDITIONER UNIT 有权
标题翻译：化学机械抛光装置，具有调色盘和预调器单元
公开(公告)号：US20120083189A1
公开(公告)日：2012-04-05
申请号：US13241421
申请日：2011-09-23
申请人： Jae-Kwang Choi , Hong-Jin Kim , Keon-Sik Seo , Sol Han , Kun-Tack Lee , Byoung-Ho Kwon
发明人： Jae-Kwang Choi , Hong-Jin Kim , Keon-Sik Seo , Sol Han , Kun-Tack Lee , Byoung-Ho Kwon
IPC分类号： B24B1/00 , B24B57/00 , B24B41/06 , B24B55/00
CPC分类号： B24B53/017
摘要： A pad conditioning disk, a pre-conditioning unit, and a CMP apparatus having the same are provided. The pad conditioning disk includes a base in which mountain-type tips and valley-type grooves are repeatedly connected to each other, and a cutting layer formed on the base layer. The cutting layer including conditioning particles deposited on surfaces of the tips and grooves. A surfaces roughness of conditioning particles deposited on the surfaces of the tips is less than a surface roughness of conditioning particles deposited on the surfaces of the grooves.
摘要翻译：提供了衬垫调节盘，预调节单元和具有该调节盘的CMP设备。垫调节盘包括其中山型尖端和谷型沟槽彼此重复连接的基底和形成在基底层上的切割层。切割层包括沉积在尖端和凹槽表面上的调节颗粒。沉积在尖端表面上的调理颗粒的表面粗糙度小于沉积在凹槽表面上的调理颗粒的表面粗糙度。

8. 发明授权

US07209200B2 Reflective and transflective liquid crystal display devices and a fabricating method thereof 有权
标题翻译：反射和透反液晶显示装置及其制造方法
公开(公告)号：US07209200B2
公开(公告)日：2007-04-24
申请号：US11246067
申请日：2005-10-11
申请人： Joo-Soo Lim , Hong-Jin Kim
发明人： Joo-Soo Lim , Hong-Jin Kim
IPC分类号： G02F1/1335 , G02F1/1339
CPC分类号： G02F1/136227 , G02F1/133555
摘要： An array substrate for a transflective liquid crystal display device which includes a substrate having a display region and a boundary region; a gate line disposed on the substrate; a first insulating layer disposed on the gate line; a data line disposed on the first insulating layer, the data line crossing the gate line and defining a pixel region with the gate line; a thin film transistor connected to the gate line and the data line; a second insulating layer disposed on the thin film transistor; a reflective plate disposed on the second insulating layer at the display region, the reflective plate being extended to the boundary region and having a transmission hole in the pixel region; a third insulating layer disposed on the reflective plate; and a pixel electrode disposed on the third insulating layer at the pixel region, the pixel electrode being connected to the thin film transistor.
摘要翻译：一种半透射型液晶显示装置的阵列基板，包括具有显示区域和边界区域的基板; 设置在基板上的栅极线; 设置在栅极线上的第一绝缘层; 设置在所述第一绝缘层上的数据线，所述数据线与所述栅极线交叉并且限定具有所述栅极线的像素区域; 连接到栅极线和数据线的薄膜晶体管; 设置在所述薄膜晶体管上的第二绝缘层; 在所述显示区域设置在所述第二绝缘层上的反射板，所述反射板延伸到所述边界区域并且在所述像素区域中具有透射孔; 设置在所述反射板上的第三绝缘层; 以及像素电极，设置在所述像素区域的所述第三绝缘层上，所述像素电极与所述薄膜晶体管连接。

9. 发明申请

US20060150051A1 Apparatus and method for selecting redundancy version 有权
公开(公告)号：US20060150051A1
公开(公告)日：2006-07-06
申请号：US11322272
申请日：2005-12-29
申请人： Sung-Lark Kwon , Hee-Gul Park , Hong-Jin Kim , Hoo-Young Jeong
发明人： Sung-Lark Kwon , Hee-Gul Park , Hong-Jin Kim , Hoo-Young Jeong
IPC分类号： H04L1/18
CPC分类号： H04L1/1819 , H04L1/0009
摘要： An apparatus and method for maximizing throughout for HARQ transmissions is provided. Systematic and prodeduralized RV selection is facilitated by determining the parameter “s” by using two important factors affecting the system throughout, specifically the coding gain varying according to the code rate and the balance between energy per systematic bit and energy per parity bit.

10. 发明申请

US20060033869A1 Reflective and transflective liquid crystal display devices and a fabricating method thereof 有权
公开(公告)号：US20060033869A1
公开(公告)日：2006-02-16
申请号：US11246067
申请日：2005-10-11
申请人： Joo-Soo Lim , Hong-Jin Kim
发明人： Joo-Soo Lim , Hong-Jin Kim
IPC分类号： G02F1/1335
CPC分类号： G02F1/136227 , G02F1/133555
摘要： An array substrate for a transflective liquid crystal display device which includes a substrate having a display region and a boundary region; a gate line disposed on the substrate; a first insulating layer disposed on the gate line; a data line disposed on the first insulating layer, the data line crossing the gate line and defining a pixel region with the gate line; a thin film transistor connected to the gate line and the data line; a second insulating layer disposed on the thin film transistor; a reflective plate disposed on the second insulating layer at the display region, the reflective plate being extended to the boundary region and having a transmission hole in the pixel region; a third insulating layer disposed on the reflective plate; and a pixel electrode disposed on the third insulating layer at the pixel region, the pixel electrode being connected to the thin film transistor.

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