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1. 发明授权

US08213007B2 Spectrally sensing chemical and biological substances 有权
标题翻译：光谱传感化学和生物物质
公开(公告)号：US08213007B2
公开(公告)日：2012-07-03
申请号：US12625970
申请日：2009-11-25
申请人： Hong Wang , Xun Guo , Chunwei Liu
发明人： Hong Wang , Xun Guo , Chunwei Liu
IPC分类号： G01J3/28
CPC分类号： G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0264 , G01J3/44 , G01N21/65 , G01N21/658 , G01N21/7703 , G01N2021/7773 , G01N2201/084 , G01N2201/129
摘要： A sensor-network system for spectrally sensing a chemical or biological substance includes a plurality of probe assemblies that each includes a sensor comprising a nano structured surface, wherein the nano structured surface can adsorb molecules of a sample material captured adjacent to the sensor; a laser configured to emit a laser beam to illuminate the molecules adsorbed to the nano structured surface, and a spectrometer that can obtain spectral data from light scattered by the molecules adsorbed to the nano structured surface. A control center includes a computer storage configured to store spectral signatures each associated with a chemical or biological substance and a spectral analyzer that can determine a spectral signature matching at least one of the spectral signatures stored in the computer storage thereby to identify, in the sample material, the chemical or biological substance associated with the one of the spectral signatures.
摘要翻译：用于光谱感测化学或生物物质的传感器网络系统包括多个探针组件，每个探针组件包括包含纳米结构化表面的传感器，其中所述纳米结构化表面可以吸附邻近所述传感器捕获的样品材料的分子; 配置为发射激光束以照射吸附到纳米结构化表面的分子的激光器，以及可以由吸附到纳米结构化表面的分子散射的光获得光谱数据的光谱仪。控制中心包括被配置为存储每个与化学或生物物质相关联的光谱特征的计算机存储器，以及光谱分析器，其可以确定与存储在计算机存储器中的至少一个光谱特征匹配的光谱特征，从而在样本中识别材料，与光谱特征之一相关联的化学或生物物质。

2. 发明授权

US08699019B2 Assuring food safety using nano-structure based spectral sensing 失效
标题翻译：使用基于纳米结构的光谱感测来确保食品安全
公开(公告)号：US08699019B2
公开(公告)日：2014-04-15
申请号：US13442835
申请日：2012-04-09
申请人： Hong Wang , Xun Guo , Chunwei Liu , Hao Zhou , Ning Ma , Xue Zhong
发明人： Hong Wang , Xun Guo , Chunwei Liu , Hao Zhou , Ning Ma , Xue Zhong
IPC分类号： G01J3/44
CPC分类号： G01N33/03 , B82Y30/00 , G01N21/64 , G01N21/65 , G01N33/497
摘要： A method for inspecting an edible oil includes obtaining a first Raman spectrum from an edible oil sample, discovering an unhealthy, unsanitary, unsafe, or adulterated content in the edible oil sample in part by the intensity level of the fluorescence background in the first Raman spectrum, introducing the edible oil sample to nano-scale surface structures to allow molecules of the edible oil sample to be adsorbed to the nano-scale surface structures, illuminating the edible oil sample and the nano-scale surface structures by a laser beam, obtaining a second Raman spectrum from light scattered by molecules of the edible oil sample adsorbed to the nano-scale surface structures, and identifying the unhealthy, unsanitary, or unsafe content in the edible oil sample using one or more first spectral signatures in the second Raman spectrum.
摘要翻译：用于检查食用油的方法包括从食用油样品获得第一拉曼光谱，部分地发现食用油样品中不健康，不卫生，不安全或掺假的含量，部分由第一拉曼光谱中的荧光背景的强度水平将食用油样品引入纳米级表面结构，使食用油样品的分子吸附到纳米级表面结构上，用激光束照射食用油样品和纳米级表面结构，得到第二拉曼光谱从被吸收到纳米级表面结构的食用油样品的分子散射的光中，以及使用第二拉曼光谱中的一个或多个第一光谱特征识别食用油样品中的不健康，不卫生或不安全的含量。

3. 发明申请

US20100085564A1 SYSTEMS AND METHODS FOR DETECTING CHEMICAL AND BIOLOGICAL SUBSTANCES 有权
标题翻译：用于检测化学和生物物质的系统和方法
公开(公告)号：US20100085564A1
公开(公告)日：2010-04-08
申请号：US12403522
申请日：2009-03-13
申请人： Xun Guo , Hong Wang , Chunwei Liu
发明人： Xun Guo , Hong Wang , Chunwei Liu
IPC分类号： G01J3/44
CPC分类号： G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/44 , G01N21/15 , G01N21/658 , G01N21/94 , G01N2021/656
摘要： A method for detecting an ingredient in a food product or detecting a disease includes allowing a food sample solution obtained from a food product or a body fluid from an individual to come to contact with a nano-scale surface structure in a sensor, wherein the nano-scale surface structure comprises a plurality of columns over a substrate or a plurality of holes in a substrate. The method includes illuminating the food sample solution or the body fluid on the nano-scale surface structure on the sensor by a laser beam; obtaining a Raman spectrum from the scattered light using a spectral analyzer; and identifying the spectral signature in the Raman spectrum to determine the existence of the chemical substance in the food product or identifying a disease in the individual.
摘要翻译：用于检测食品中的成分或检测疾病的方法包括使得从个体的食品或体液获得的食品样品溶液与传感器中的纳米级表面结构接触，其中所述纳米尺寸表面结构包括在衬底上的多个柱或衬底中的多个孔。该方法包括通过激光束照射传感器上的纳米级表面结构上的食物样品溶液或体液; 使用光谱分析仪从散射光获得拉曼光谱; 并确定拉曼光谱中的光谱特征，以确定食品中化学物质的存在或识别个体中的疾病。

4. 发明授权

US08582099B2 Monitoring network based on nano-structured sensing devices 失效
标题翻译：基于纳米结构感测器件的监控网络
公开(公告)号：US08582099B2
公开(公告)日：2013-11-12
申请号：US13080142
申请日：2011-04-05
申请人： Xun Guo , Hong Wang , Chunwei Liu
发明人： Xun Guo , Hong Wang , Chunwei Liu
IPC分类号： G01J3/28
CPC分类号： G01N21/658 , B82Y20/00 , B82Y40/00 , G01N33/54346
摘要： A monitoring network system for inspecting and controlling harmful substances includes probe assemblies that each includes a sensor comprising nano structured surfaces or nano particles in a solution, configured to adsorb molecules of a sample material captured adjacent to the sensor, a laser that can emit a laser beam to illuminate the molecules adsorbed to the nano structured surfaces, a spectrometer that can produce spectral data from light scattered by the molecules adsorbed to the nano structured surfaces, and a ID reader that can retrieve identification information about the sample material. A central office can determine a spectral signature matching spectral signatures stored in a database and to identify a harmful substance in the sample material. An alert and response system can send out an alert signal about the sample material when the harmful substance is identified in the sample material.
摘要翻译：用于检查和控制有害物质的监测网络系统包括探针组件，每个探针组件包括在溶液中包含纳米结构化表面或纳米颗粒的传感器，其被配置为吸附邻近传感器捕获的样品材料的分子，可以发射激光光束照射吸附到纳米结构化表面的分子，可以由吸附到纳米结构化表面的分子散射的光产生光谱数据的光谱仪，以及可以检索关于样品材料的识别信息的ID读取器。中心局可以确定与数据库中存储的光谱签名相匹配的光谱签名，并识别样品中的有害物质。当在样品材料中识别有害物质时，警报和响应系统可以发出关于样品材料的警报信号。

5. 发明申请

US20100070197A1 SPECTRALLY SENSING CHEMICAL AND BIOLOGICAL SUBSTANCES 有权
标题翻译：光谱传感化学和生物物质
公开(公告)号：US20100070197A1
公开(公告)日：2010-03-18
申请号：US12625970
申请日：2009-11-25
申请人： Hong Wang , Xun Guo , Chunwei Liu
发明人： Hong Wang , Xun Guo , Chunwei Liu
IPC分类号： G01J3/44 , G06F19/00 , G01J3/30
CPC分类号： G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0264 , G01J3/44 , G01N21/65 , G01N21/658 , G01N21/7703 , G01N2021/7773 , G01N2201/084 , G01N2201/129
摘要： A sensor-network system for spectrally sensing a chemical or biological substance includes a plurality of probe assemblies that each includes a sensor comprising a nano structured surface, wherein the nano structured surface can adsorb molecules of a sample material captured adjacent to the sensor; a laser configured to emit a laser beam to illuminate the molecules adsorbed to the nano structured surface, and a spectrometer that can obtain spectral data from light scattered by the molecules adsorbed to the nano structured surface. A control center includes a computer storage configured to store spectral signatures each associated with a chemical or biological substance and a spectral analyzer that can determine a spectral signature matching at least one of the spectral signatures stored in the computer storage thereby to identify, in the sample material, the chemical or biological substance associated with the one of the spectral signatures.
摘要翻译：用于光谱感测化学或生物物质的传感器网络系统包括多个探针组件，每个探针组件包括包含纳米结构化表面的传感器，其中所述纳米结构化表面可以吸附邻近所述传感器捕获的样品材料的分子; 配置为发射激光束以照射吸附到纳米结构化表面的分子的激光器，以及可以由吸附到纳米结构化表面的分子散射的光获得光谱数据的光谱仪。控制中心包括被配置为存储每个与化学或生物物质相关联的光谱特征的计算机存储器，以及光谱分析器，其可以确定与存储在计算机存储器中的至少一个光谱特征匹配的光谱签名，从而在样本中识别材料，与光谱特征之一相关联的化学或生物物质。

6. 发明申请

US20130017298A1 ASSURING FOOD SAFETY USING NANO-STRUCTURE BASED SPECTRAL SENSING 失效
标题翻译：使用基于纳米结构的光谱感测来保证食品安全
公开(公告)号：US20130017298A1
公开(公告)日：2013-01-17
申请号：US13442835
申请日：2012-04-09
申请人： Hong Wang , Xun Guo , Chunwei Liu , Hao Zhou , Ning Ma , Xue Zhong
发明人： Hong Wang , Xun Guo , Chunwei Liu , Hao Zhou , Ning Ma , Xue Zhong
IPC分类号： G01N33/03 , B82Y99/00
CPC分类号： G01N33/03 , B82Y30/00 , G01N21/64 , G01N21/65 , G01N33/497
摘要： A method for inspecting an edible oil includes obtaining a first Raman spectrum from an edible oil sample, discovering an unhealthy, unsanitary, unsafe, or adulterated content in the edible oil sample in part by the intensity level of the fluorescence background in the first Raman spectrum, introducing the edible oil sample to nano-scale surface structures to allow molecules of the edible oil sample to be adsorbed to the nano-scale surface structures, illuminating the edible oil sample and the nano-scale surface structures by a laser beam, obtaining a second Raman spectrum from light scattered by molecules of the edible oil sample adsorbed to the nano-scale surface structures, and identifying the unhealthy, unsanitary, or unsafe content in the edible oil sample using one or more first spectral signatures in the second Raman spectrum.
摘要翻译：用于检查食用油的方法包括从食用油样品获得第一拉曼光谱，部分地发现食用油样品中不健康，不卫生，不安全或掺假的含量，部分由第一拉曼光谱中的荧光背景的强度水平将食用油样品引入纳米级表面结构，使食用油样品的分子吸附到纳米级表面结构上，用激光束照射食用油样品和纳米级表面结构，得到第二拉曼光谱从被吸收到纳米级表面结构的食用油样品的分子散射的光中，以及使用第二拉曼光谱中的一个或多个第一光谱特征识别食用油样品中的不健康，不卫生或不安全的含量。

7. 发明授权

US08102525B2 Systems and methods for detecting chemical and biological substances 有权
标题翻译：用于检测化学和生物物质的系统和方法
公开(公告)号：US08102525B2
公开(公告)日：2012-01-24
申请号：US12403522
申请日：2009-03-13
申请人： Xun Guo , Hong Wang , Chunwei Liu
发明人： Xun Guo , Hong Wang , Chunwei Liu
IPC分类号： G01J3/44
CPC分类号： G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/44 , G01N21/15 , G01N21/658 , G01N21/94 , G01N2021/656
摘要： A method for detecting an ingredient in a food product or detecting a disease includes allowing a food sample solution obtained from a food product or a body fluid from an individual to come to contact with a nano-scale surface structure in a sensor, wherein the nano-scale surface structure comprises a plurality of columns over a substrate or a plurality of holes in a substrate. The method includes illuminating the food sample solution or the body fluid on the nano-scale surface structure on the sensor by a laser beam; obtaining a Raman spectrum from the scattered light using a spectral analyzer; and identifying the spectral signature in the Raman spectrum to determine the existence of the chemical substance in the food product or identifying a disease in the individual.
摘要翻译：用于检测食品中的成分或检测疾病的方法包括使得从个体的食品或体液获得的食品样品溶液与传感器中的纳米级表面结构接触，其中所述纳米尺寸表面结构包括在衬底上的多个柱或衬底中的多个孔。该方法包括通过激光束照射传感器上的纳米级表面结构上的食物样品溶液或体液; 使用光谱分析仪从散射光获得拉曼光谱; 并确定拉曼光谱中的光谱特征，以确定食品中化学物质的存在或识别个体中的疾病。

8. 发明授权

US07956997B2 Systems and methods for food safety detection 有权
标题翻译：食品安全检测系统和方法
公开(公告)号：US07956997B2
公开(公告)日：2011-06-07
申请号：US12246616
申请日：2008-10-07
申请人： Hong Wang , Xun Guo , Chunwei Liu
发明人： Hong Wang , Xun Guo , Chunwei Liu
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01N21/15 , G01N21/658 , G01N21/94 , G01N2021/656
摘要： A method for detecting an ingredient in a food product includes establishing a spectral signature in a Raman spectrum obtained from a chemical substance; allowing a food sample solution obtained from a food product to come to contact with a first nano-scale surface structure in a first sensor, wherein the first sensor comprises a substrate, wherein the nano-scale surface structure comprises a plurality of columns over the substrate or a plurality of holes in the substrate; illuminating the food sample solution and the first nano-scale surface structure on the first sensor by a laser beam; scattering the laser beam by the food sample solution and the first nano-scale surface structure to produce a scattered light; obtaining a first Raman spectrum from the scattered light using a spectral analyzer; and identifying the spectral signature in the first Raman spectrum to determine the existence of the chemical substance in the food product.
摘要翻译：检测食品中成分的方法包括：以化学物质获得的拉曼光谱建立光谱特征; 允许从食品获得的食品样品溶液与第一传感器中的第一纳米级表面结构接触，其中所述第一传感器包括基底，其中所述纳米级表面结构包括在所述基底上的多个柱或基板中的多个孔; 通过激光束照射第一传感器上的食物样品溶液和第一纳米级表面结构; 通过食品样品溶液和第一纳米级表面结构散射激光束以产生散射光; 使用光谱分析仪从散射光获得第一拉曼光谱; 并确定第一拉曼光谱中的光谱特征，以确定食品中化学物质的存在。

9. 发明申请

US20090046284A1 SYSTEMS AND METHODS FOR FOOD SAFETY DETECTION 有权
标题翻译：食品安全检测系统和方法
公开(公告)号：US20090046284A1
公开(公告)日：2009-02-19
申请号：US12246616
申请日：2008-10-07
申请人： Honh Wang , Xun Guo , Chunwei Liu
发明人： Honh Wang , Xun Guo , Chunwei Liu
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01N21/15 , G01N21/658 , G01N21/94 , G01N2021/656
摘要： A method for detecting an ingredient in a food product includes establishing a spectral signature in a Raman spectrum obtained from a chemical substance; allowing a food sample solution obtained from a food product to come to contact with a first nano-scale surface structure in a first sensor, wherein the first sensor comprises a substrate, wherein the nano-scale surface structure comprises a plurality of columns over the substrate or a plurality of holes in the substrate; illuminating the food sample solution and the first nano-scale surface structure on the first sensor by a laser beam; scattering the laser beam by the food sample solution and the first nano-scale surface structure to produce a scattered light; obtaining a first Raman spectrum from the scattered light using a spectral analyzer; and identifying the spectral signature in the first Raman spectrum to determine the existence of the chemical substance in the food product.
摘要翻译：检测食品中成分的方法包括：以化学物质获得的拉曼光谱建立光谱特征; 允许从食品获得的食品样品溶液与第一传感器中的第一纳米级表面结构接触，其中所述第一传感器包括基底，其中所述纳米级表面结构包括在所述基底上的多个柱或基板中的多个孔; 通过激光束照射第一传感器上的食物样品溶液和第一纳米级表面结构; 通过食品样品溶液和第一纳米级表面结构散射激光束以产生散射光; 使用光谱分析仪从散射光获得第一拉曼光谱; 并确定第一拉曼光谱中的光谱特征，以确定食品中化学物质的存在。

10. 发明授权

US08031335B2 Non-invasive disease diagnosis using light scattering probe 有权
标题翻译：使用光散射探针的非侵入性疾病诊断
公开(公告)号：US08031335B2
公开(公告)日：2011-10-04
申请号：US12176383
申请日：2008-07-20
申请人： Hong Wang , Xun Guo
发明人： Hong Wang , Xun Guo
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , G01J3/02 , G01J3/021 , G01N21/658 , G08B21/12
摘要： A method for non-invasive detection of a disease, a status of illicit-drug use, or smoking status includes transferring a body fluid obtained from a patient to a sensor comprising a nano-scale surface structure to allow the body fluid to come in contact with the nano-scale surface structure, illuminating the body fluid and the nano-scale surface structure by a laser beam, scattering the laser beam by the body fluid and the nano-scale surface structure to produce a scattered light, and analyzing the scattered light using a spectral analyzer to diagnose a disease, the status of illicit-drug use, or smoking status in the patient.
摘要翻译：用于非侵入性检测疾病，非法药物使用状况或吸烟状态的方法包括将从患者获得的体液转移到包括纳米级表面结构的传感器以允许体液接触通过纳米级表面结构，通过激光照射体液和纳米级表面结构，通过体液和纳米级表面结构散射激光束产生散射光，并分析散射光使用光谱分析仪诊断疾病，非法药物使用状况或患者的吸烟状况。

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