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1. 发明申请

US20140121347A1 HIGH MOLECULAR WEIGHT POLYLACTIC ACID SYNTHESIZED VIA POLYCONDENSATION CATALYZED BY BIONIC CREATININE GUANIDININIUM CHLORIDE 有权
标题翻译：高分子量聚乳酸通过生物金刚烷胺氯化物催化的多元醇合成
公开(公告)号：US20140121347A1
公开(公告)日：2014-05-01
申请号：US14129323
申请日：2011-11-02
申请人： Hong Li , Quanxing Zhang , Wei Huang , Wei Jiang , Xupeng Zong , Bingcai Pan
发明人： Hong Li , Quanxing Zhang , Wei Huang , Wei Jiang , Xupeng Zong , Bingcai Pan
IPC分类号： C08G63/87 , C07D233/50
CPC分类号： C07D233/50 , A61K47/34 , A61L17/12 , A61L27/18 , A61L31/06 , C07D233/32 , C07D233/46 , C07D233/88 , C08G63/06 , C08G63/87
摘要： Disclosed is a high molecular weight polylactic acid synthesized by using a method for synthesizing and catalytically-polycondensing bionic creatinine-guanidinium chloride. Creatinine is used as the material in a reaction with aqueous hydrochloric acid to synthesize a bionic creatinine-guanidinium salt catalyst, creatinine-guanidinium chloride (CR.Cl). The creatinine-guanidinium chloride synthesized is used as a catalyst, an industrial grade lactic acid (LA, 85% to 90%, aqueous solution) is used as a monomer, a solvent-free two-step polycondensation method is used to synthesize and afford metal-free and toxic residue-free polylactic acid featuring high biological safety and high molecular weight.
摘要翻译：本发明公开了一种通过使用合成和催化缩聚仿生肌酐 - 氯化胍的方法合成的高分子量聚乳酸。使用肌酸酐作为与盐酸水溶液反应的材料，以合成肌酸酐 - 胍盐催化剂，肌酸酐 - 氯化胍（CR.Cl）。使用合成的肌酸胍 - 氯化胍作为催化剂，使用工业级乳酸（LA，85％〜90％，水溶液）作为单体，使用无溶剂的两步缩聚法合成并提供无金属和无毒无残留的聚乳酸，具有高生物安全性和高分子量。

2. 发明授权

US09062006B2 High molecular weight polylactic acid synthesized via polycondensation catalyzed by bionic creatinine guanidinium chloride 有权
标题翻译：通过由仿生肌酐氯化胍催化的缩聚合成的高分子量聚乳酸
公开(公告)号：US09062006B2
公开(公告)日：2015-06-23
申请号：US14129323
申请日：2011-11-02
申请人： Hong Li , Quanxing Zhang , Wei Huang , Wei Jiang , Xupeng Zong , Bingcai Pan
发明人： Hong Li , Quanxing Zhang , Wei Huang , Wei Jiang , Xupeng Zong , Bingcai Pan
IPC分类号： C08G63/87 , C07D233/50 , A61L27/18 , A61L31/06 , A61K47/34 , A61L17/12 , C07D233/32 , C08G63/06
CPC分类号： C07D233/50 , A61K47/34 , A61L17/12 , A61L27/18 , A61L31/06 , C07D233/32 , C07D233/46 , C07D233/88 , C08G63/06 , C08G63/87
摘要： Disclosed is a high molecular weight polylactic acid synthesized by using a method for synthesizing and catalytically-polycondensing bionic creatinine-guanidinium chloride. Creatinine is used as the material in a reaction with aqueous hydrochloric acid to synthesize a bionic creatinine-guanidinium salt catalyst, creatinine-guanidinium chloride (CR.Cl). The creatinine-guanidinium chloride synthesized is used as a catalyst, an industrial grade lactic acid (LA, 85% to 90%, aqueous solution) is used as a monomer, a solvent-free two-step polycondensation method is used to synthesize and afford metal-free and toxic residue-free polylactic acid featuring high biological safety and high molecular weight.
摘要翻译：本发明公开了一种通过使用合成和催化缩聚仿生肌酐 - 氯化胍的方法合成的高分子量聚乳酸。使用肌酸酐作为与盐酸水溶液反应的材料，以合成肌酸酐 - 胍盐催化剂，肌酸酐 - 氯化胍（CR.Cl）。使用合成的肌酸胍 - 氯化胍作为催化剂，使用工业级乳酸（LA，85％〜90％，水溶液）作为单体，使用无溶剂的两步缩聚法合成并提供无金属和无毒无残留的聚乳酸，具有高生物安全性和高分子量。

3. 发明授权

US08846853B2 Polycondensation of lactic acid for medical biodegradable polylactic acid catalyzed by creatinine 有权
标题翻译：乳酸对肌酸酐催化的医用可生物降解聚乳酸的缩聚
公开(公告)号：US08846853B2
公开(公告)日：2014-09-30
申请号：US13511311
申请日：2011-11-03
申请人： Hong Li , Quanxing Zhang , Wei Jiang , Wei Huang , Bingcai Pan
发明人： Hong Li , Quanxing Zhang , Wei Jiang , Wei Huang , Bingcai Pan
IPC分类号： C08G63/08 , A61K47/32 , C08G63/82
CPC分类号： C08G63/823 , A61K47/32 , C08G63/08
摘要： A direct polycondensation method for medical biodegradable polylactic acid (PLA). The invention uses commercialized creatinine (a type of biomaterial organic guanidine compounds—the arginine metabolite creatinine in human body) as the catalyst and industrial lactic acid (mass content 85-90%, aqueous solution) as the monomer to synthesize the PLA in terms of second polycondensation without solvent. Instead of tin catalysts having cytotoxicity, the catalyst used in the invention has high biocompatibility and biosafety. The synthesized PLA does not contain any metal and other toxic components; therefore, it can be used as the carrier for targeting drugs and controlled release drugs. The green catalyst and green processing method (no solvent applied and no toxic products produced) are used to synthesize the green biodegradable PLA with high biosafety. The molecular weight distribution for all synthesized products is narrow and the molecular weight is controllable within 1.5-3.0×104.
摘要翻译：医用可生物降解聚乳酸（PLA）的直接缩聚方法。本发明使用商业化肌酐（一种生物材料有机胍化合物 - 人体中的精氨酸代谢物肌酸酐）作为催化剂，工业乳酸（质量含量85-90％，水溶液）作为单体合成PLA 第二次缩聚无溶剂。代替具有细胞毒性的锡催化剂，本发明中使用的催化剂具有高生物相容性和生物安全性。合成的PLA不含任何金属和其他有毒成分; 因此，它可以用作靶向药物和控释药物的载体。使用绿色催化剂和绿色加工方法（无溶剂应用，无有毒产物生产）合成具有高生物安全性的绿色生物降解PLA。所有合成产物的分子量分布窄，分子量可控1.5-3.0×104。

4. 发明申请

US20130116400A1 POLYCONDENSATION OF LACTIC ACID FOR MEDICAL BIODEGRADABLE POLYLACTIC ACID CATALYZED BY CREATININE 有权
标题翻译：用于通过CREATININE催化的医用生物可降解聚乳酸的乳酸的聚合
公开(公告)号：US20130116400A1
公开(公告)日：2013-05-09
申请号：US13511311
申请日：2011-11-03
申请人： Hong Li , Quanxing Zhang , Wei Jiang , Wei Huang , Bingcai Pan
发明人： Hong Li , Quanxing Zhang , Wei Jiang , Wei Huang , Bingcai Pan
IPC分类号： C08G63/06
CPC分类号： C08G63/823 , A61K47/32 , C08G63/08
摘要： The present invention provides a direct polycondensation method for medical biodegradable polylactic acid (PLA) using creatinine catalyzed lactic acid. The invention uses commercialized creatinine (a type of biomaterial organic guanidine compounds—the arginine metabolite creatinine (CR) in human body) as the catalyst and industrial lactic acid (LA, mass content 85-90%, aqueous solution) as the monomer to synthesize the high biosafety of medical PLA in terms of second polycondensation without solvent (identity). Instead of tin catalysts having cytotoxicity, the catalyst used in the invention has high biocompatibility and biosafety. The synthesized PLA does not contain any metal and other toxic components; therefore, it can be used as the carrier for targeting drugs and controlled release drugs. In addition, the green catalyst and green processing method (no solvent applied and no toxic products produced) are used in the invention to synthesize the green biodegradable PLA with high biosafety. The polymerization reaction is simple and the raw materials required are low in costs, thus it is easy for industrialization. Further, the molecular weight distribution for all synthesized products is narrow and the molecular weight is controllable within 1.5-3.0×104.
摘要翻译：本发明提供使用肌酸酐催化乳酸的医用可生物降解聚乳酸（PLA）的直接缩聚方法。本发明使用商业化肌酐（一种生物材料有机胍化合物 - 人体中的精氨酸代谢物肌酸酐（CR））作为催化剂，工业乳酸（LA，质量含量85-90％，水溶液）作为单体合成医用PLA的高生物安全性在无溶剂（身份）的第二缩聚方面。代替具有细胞毒性的锡催化剂，本发明中使用的催化剂具有高生物相容性和生物安全性。合成的PLA不含任何金属和其他有毒成分; 因此，它可以用作靶向药物和控释药物的载体。此外，本发明中使用绿色催化剂和绿色加工方法（无溶剂施用，无有毒产物）合成具有高生物安全性的绿色可生物降解PLA。聚合反应简单，所需原料成本低，易于工业化。此外，所有合成产物的分子量分布窄，分子量可控制在1.5-3.0×104内。

5. 发明授权

US09062159B2 Poly(lactic-co-glycolic acid) synthesized via copolycondensation catalyzed by biomass creatinine 有权
标题翻译：通过由生物质肌酐催化的共缩聚合成的聚（乳酸 - 共 - 乙醇酸）
公开(公告)号：US09062159B2
公开(公告)日：2015-06-23
申请号：US14129111
申请日：2011-11-03
申请人： Hong Li , Quanxing Zhang , Wei Jiang , Bingcai Pan
发明人： Hong Li , Quanxing Zhang , Wei Jiang , Bingcai Pan
IPC分类号： C08G63/87 , A61L27/18 , A61K47/34 , A61L17/00 , C08G63/06 , C08G63/08 , C08G63/82 , A61L27/54 , A61L17/12
CPC分类号： C08G63/87 , A61K47/34 , A61L17/00 , A61L17/12 , A61L27/18 , A61L27/54 , A61L2300/602 , A61L2430/02 , C08G63/06 , C08G63/08 , C08G63/78 , C08G63/823 , C08L67/04
摘要： A method for synthesizing a medical grade biodegradable material, poly(lactic-co-glycolic acid), copolycondensation of lactic acid and glycolic acid catalyzed by biomass creatinine. The present invention uses commercialized creatinine (a type of biomaterial organic guanidine compounds—the arginine metabolite creatinine (CR) in human body) as the catalyst and industrial lactic acid (LA, mass content 85%, aqueous solution) and glycolic acid (GA, 95%) as the monomer to synthesize the high biosafety of medical poly(lactic-co-glycolic acid) in terms of two steps polycondensation without solvent. The method of the present invention has the following characters: green technology is used, raw materials required are low in costs, operation is simple and convenient, and it is easy for industrialization; the catalyst, creatinine, used in the invention has high biocompatibility and biosafety, and no cytotoxicity; the poly(lactic-co-glycolic acid) synthesized is free of any metal and other toxic residues; Further, the molecular weight distribution for all synthesized products is narrow and the molecular weight is controllable within 1.8-17.7×104; and the poly(lactic-co-glycolic acid) synthesized is suitable for use as implantable material for hard tissue repair, surgical sutures, and the carrier for targeting drugs and controlled release drugs.
摘要翻译：用于合成医用级生物降解材料的方法，聚（乳酸 - 共 - 乙醇酸），由生物体肌酐催化的乳酸和乙醇酸的共缩聚。本发明使用商业化肌酐（一种生物材料有机胍化合物 - 人体中的精氨酸代谢物肌酸酐（CR））作为催化剂和工业乳酸（LA，质量含量85％，水溶液）和乙醇酸（GA， 95％）作为单体，以两步缩聚无溶剂的方式合成医用聚（乳酸 - 共 - 乙醇酸）的高生物安全性。本发明的方法具有以下特征：使用绿色技术，所需原料成本低，操作简单方便，工业化容易; 本发明使用的催化剂，肌酸酐具有高生物相容性和生物安全性，无细胞毒性; 合成的聚（乳酸 - 共 - 乙醇酸）不含任何金属和其他有毒残留物; 此外，所有合成产物的分子量分布窄，分子量可控于1.8-17.7×104; 合成的聚（乳酸 - 共 - 乙醇酸）适用于硬组织修复，手术缝合线和用于靶向药物和控释药物的载体的植入材料。

6. 发明申请

US20140142275A1 POLY(LACTIC-CO-GLYCOLIC ACID) SYNTHESIZED VIA COPOLYCONDENSATION CATALYZED BY BIOMASS CREATININE 有权
标题翻译：通过生物质CREATININE催化的共聚合合合成的聚（丙烯酸 - 聚乙酸）
公开(公告)号：US20140142275A1
公开(公告)日：2014-05-22
申请号：US14129111
申请日：2011-11-03
申请人： Hong Li , Quanxing Zhang , Wei Jiang , Bingcai Pan
发明人： Hong Li , Quanxing Zhang , Wei Jiang , Bingcai Pan
IPC分类号： C08G63/87
CPC分类号： C08G63/87 , A61K47/34 , A61L17/00 , A61L17/12 , A61L27/18 , A61L27/54 , A61L2300/602 , A61L2430/02 , C08G63/06 , C08G63/08 , C08G63/78 , C08G63/823 , C08L67/04
摘要： A method for synthesizing a medical grade biodegradable material, poly(lactic-co-glycolic acid), copolycondensation of lactic acid and glycolic acid catalyzed by biomass creatinine. The present invention uses commercialized creatinine (a type of biomaterial organic guanidine compounds—the arginine metabolite creatinine (CR) in human body) as the catalyst and industrial lactic acid (LA, mass content 85%, aqueous solution) and glycolic acid (GA, 95%) as the monomer to synthesize the high biosafety of medical poly(lactic-co-glycolic acid) in terms of two steps polycondensation without solvent. The method of the present invention has the following characters: green technology is used, raw materials required are low in costs, operation is simple and convenient, and it is easy for industrialization; the catalyst, creatinine, used in the invention has high biocompatibility and biosafety, and no cytotoxicity; the poly(lactic-co-glycolic acid) synthesized is free of any metal and other toxic residues; Further, the molecular weight distribution for all synthesized products is narrow and the molecular weight is controllable within 1.8-17.7×104; and the poly(lactic-co-glycolic acid) synthesized is suitable for use as implantable material for hard tissue repair, surgical sutures, and the carrier for targeting drugs and controlled release drugs.
摘要翻译：用于合成医用级生物降解材料的方法，聚（乳酸 - 共 - 乙醇酸），由生物体肌酐催化的乳酸和乙醇酸的共缩聚。本发明使用商业化肌酐（一种生物材料有机胍化合物 - 人体中的精氨酸代谢物肌酸酐（CR））作为催化剂和工业乳酸（LA，质量含量85％，水溶液）和乙醇酸（GA， 95％）作为单体，以两步缩聚无溶剂的方式合成医用聚（乳酸 - 共 - 乙醇酸）的高生物安全性。本发明的方法具有以下特征：使用绿色技术，所需原料成本低，操作简单方便，工业化容易; 本发明使用的催化剂，肌酸酐具有高生物相容性和生物安全性，无细胞毒性; 合成的聚（乳酸 - 共 - 乙醇酸）不含任何金属和其他有毒残留物; 此外，所有合成产物的分子量分布窄，分子量可控于1.8-17.7×104; 合成的聚（乳酸 - 共 - 乙醇酸）适用于硬组织修复，手术缝合线和用于靶向药物和控释药物的载体的植入材料。

7. 外观设计

USD838272S1 Wireless mini keyboard 有权
公开(公告)号：USD838272S1
公开(公告)日：2019-01-15
申请号：US29618500
申请日：2017-09-21
申请人： Wei Jiang
设计人： Wei Jiang
摘要： FIG. 1 is a front, top, left-side perspective view of the wireless mini keyboard;
FIG. 2 is a front elevational view thereof;
FIG. 3 is a top plan view thereof;
FIG. 4 is a right-side elevational view thereof;
FIG. 5 is a left-side elevational view thereof;
FIG. 6 is a rear elevational view thereof; and,
FIG. 7 is a bottom plan view thereof.

8. 发明授权

US09292600B2 Message classification and management 有权
标题翻译：消息分类和管理
公开(公告)号：US09292600B2
公开(公告)日：2016-03-22
申请号：US13250664
申请日：2011-09-30
申请人： Paul M. Midgen , Vasantha K. Vemula , Krishna Vitaldevara , Jason D. Walter , Eliot C. Gillum , Mihai Costea , Douglas J. Hines , Wei Jiang , Malcolm H. Davis , Samuel J. L. Albert , Michael James Ahiakpor
发明人： Paul M. Midgen , Vasantha K. Vemula , Krishna Vitaldevara , Jason D. Walter , Eliot C. Gillum , Mihai Costea , Douglas J. Hines , Wei Jiang , Malcolm H. Davis , Samuel J. L. Albert , Michael James Ahiakpor
IPC分类号： G06F15/16 , H04L12/58 , H04L29/06 , H04L29/08 , G06F17/30 , G06Q10/10
CPC分类号： H04L51/22 , G06F3/0482 , G06F3/04842 , G06F17/30601 , G06F17/30707 , G06Q10/107 , H04L51/14
摘要： Message management and classification techniques are described. In one or more implementations, a message received from a sender for delivery via a user account is examined to extract one or more features of the message. A determination is then made as to whether the message corresponds to one or more categories based on the extracted features, the categories usable to enable features to be applied to the message in a user interface.
摘要翻译：描述消息管理和分类技术。在一个或多个实现中，检查从发送者接收的用于经由用户帐户递送的消息以提取消息的一个或多个特征。然后，基于所提取的特征，确定消息是否对应于一个或多个类别，可用于使特征能够应用于用户界面中的消息的类别。

9. 发明授权

US09147762B2 Semiconductor device and method for manufacturing the same 有权
标题翻译：半导体装置及其制造方法
公开(公告)号：US09147762B2
公开(公告)日：2015-09-29
申请号：US14354648
申请日：2012-07-31
申请人： Haizhou Yin , Wei Jiang , Huilong Zhu
发明人： Haizhou Yin , Wei Jiang , Huilong Zhu
IPC分类号： H01L27/01 , H01L29/78 , H01L29/10 , H01L29/165 , H01L29/66
CPC分类号： H01L29/78 , H01L29/1054 , H01L29/165 , H01L29/66477 , H01L29/66545 , H01L29/6659 , H01L29/66636 , H01L29/7833 , H01L29/7848
摘要： A semiconductor device and a method for manufacturing the same are provided. In one embodiment, the method comprises: growing a first epitaxial layer on a substrate; forming a sacrificial gate stack on the first epitaxial layer; selectively etching the first epitaxial layer; growing and in-situ doping a second epitaxial layer on the substrate; forming a spacer on opposite sides of the sacrificial gate stack; and forming source/drain regions with the spacer as a mask.
摘要翻译：提供半导体器件及其制造方法。在一个实施例中，该方法包括：在衬底上生长第一外延层; 在所述第一外延层上形成牺牲栅叠层; 选择性地蚀刻第一外延层; 在衬底上生长并原位掺杂第二外延层; 在所述牺牲栅极堆叠的相对侧上形成间隔物; 以及用间隔物形成源极/漏极区域作为掩模。

10. 发明授权

US09087324B2 Message categorization 有权
标题翻译：消息分类
公开(公告)号：US09087324B2
公开(公告)日：2015-07-21
申请号：US13180838
申请日：2011-07-12
申请人： Ivan Osipkov , Wei Jiang , Malcolm Hollis Davis , Douglas Hines , Joshua Korb
发明人： Ivan Osipkov , Wei Jiang , Malcolm Hollis Davis , Douglas Hines , Joshua Korb
IPC分类号： G06F15/16 , G06Q10/10
CPC分类号： H04L51/22 , G06Q10/107 , H04L67/306
摘要： One or more techniques and/or systems are provided for defining a message behavior profile for a sender, which may be used to categorize messages from the sender. A message behavior profile may be defined based upon, for example, message distribution behavior of the sender (e.g., volume, frequency, variance in content amongst messages sent to recipients, etc.); recipient interactions with messages from the sender (e.g., message read rates, message response rates, etc.); unsubscription options comprised within messages from the sender; and/or other factors. In this way, the message behavior profile and/or features extracted from a message may be used to categorize a message from the sender (e.g., newsletter, commercial advertisements, alert, social network etc.). Categorized messages may be organized into folders, displayed or hidden within views, and/or processed based upon their respective categorizations.
摘要翻译：提供一个或多个技术和/或系统来定义用于发送者的消息行为简档，其可以用于对来自发送者的消息进行分类。可以基于例如发送者的消息分发行为（例如，音量，频率，发送给接收者的消息中的内容的差异等）来定义消息行为简档; 收件人与来自发送者的消息的交互（例如，消息读取速率，消息响应速率等）; 来自发件人的邮件中包含的取消订阅选项; 和/或其他因素。以这种方式，消息行为简档和/或从消息提取的特征可以用于对来自发送者的消息进行分类（例如，通讯，商业广告，警报，社交网络等）。分类的消息可以被组织成在视图内显示或隐藏的文件夹，和/或基于它们各自的分类进行处理。

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