专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20100255127A1 AROMATASE INHIBITOR 审中-公开
标题翻译：芳香酶抑制剂
公开(公告)号：US20100255127A1
公开(公告)日：2010-10-07
申请号：US12744320
申请日：2008-11-20
申请人： Hisayoshi Norimoto , Yasuo Morimoto
发明人： Hisayoshi Norimoto , Yasuo Morimoto
IPC分类号： A61K36/00 , A61K36/49 , A61K36/736 , A61K36/15 , A61K36/38 , A61K36/82 , A61P3/00 , A61P15/00
CPC分类号： A61K36/00 , A61K2300/00
摘要： Disclosed is a safe substance which can inhibit the activity of aromatase (an enzyme capable of converting androgen into estrogen) to thereby effectively treat and/or prevent a sex hormone-dependent disease such as breast cancer occurring in a female person after menopause, as well as a climacteric disorder in a male person and metabolic syndrome caused by the accumulation of a visceral fat. Specifically disclosed is a therapeutic and/or prophylactic agent for a sex hormone-dependent disease, which is characterized by comprising at least one herbal extract selected from the group consisting of “Kokeiten” (golden root), prunella spike, sweet hydrangea leaf, milk thistle, a jasmine tea, “Bokusoku” (a bark of Quercus acutissima or a closely related plant thereof), “Tencha” (sweet tea), “Karensou” (Eclipta prostrata), “Youbaihi” (a bark of Myrica rubra Sie b. et Zucc.), French maritime pine, betel palm, asparagus, “Rouro” (a root of Rhaponticum unifloru m DC. or Echinops latifolius Tausch), “Ryoukyou” (a rhizome of Alpinia officinarum Hance), rooibos tea, rhubarb, pu-erh tea, green tea, “Ougon” (a root of Scutellaria baicalensis Georgi), St. John's wort (Hypericum perforatum L.), licorice, “Senrikou” (Senecio scandens Buch.-Ham.), wintergreen, “Kashi” (a matured fruit of Terminalia chebula Retz.), “Yagotou” (a bark of Mallotus japonicus), polygnum root, barrenwort (Epimedium Herb), guarana, “Ouhi” (a bark of Prunus jamasakura Sieb. ex. Koidz. or a closely related plant thereof), Argy's wormwood, sticky rehmannia, Japanese cornel, Asiasarum root, cinnamon, peony root, pine needle and amla fruit.
摘要翻译：公开了一种可以抑制芳香酶（能够将雄激素转化成雌激素的酶）的活性的安全物质，从而有效地治疗和/或预防绝经后雌激素依赖性疾病如乳腺癌发生在女性中，以及作为男性人的更年期疾病和由内脏脂肪积累引起的代谢综合征。具体公开了一种性激素依赖性疾病的治疗剂和/或预防剂，其特征在于，含有至少一种草药提取物，其选自“Kokeiten”（金根），ella ike，甜绣球叶，牛奶蓟，一种茉莉花茶“Bokusoku”（栎栎或其密切相关的植物），“Tencha”（甜茶），“Karensou”（Eclipta prostrata），“Youbaihi”（Myrica rubra Sie b ，法国海洋松，槟榔，芦笋，“Rouro”（Rhaponticum unifloru m DC的根或Echinops latifolius Tausch），“Ryoukyou”（Alpinia officinarum Hance的根茎），rooibos茶，大黄，普洱茶，绿茶，“Ougon”（黄芩的根），圣约翰草（Hypericum perforatum L.），甘草，“Senrikou”（Senecio scandens Buch.-Ham。），冬青，“喀什 “（Terminalia chebula Retz的成熟果实），”Yagotou“（Mallotus japoni的树皮 cus），杜鹃根，bar草（Epimedium Herb），瓜拉纳，“Ouhi”（杏仁树皮Sieb的树皮）。例如 Koidz。或其密切相关的植物），Argy的蒿木，粘土地幔，日本cor木，亚洲根，肉桂，牡丹根，松针和amla水果。

IPRDB

热门服务

关于我们

友情链接

联系方式