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    • 5. 发明申请
    • Process for the production of diglycerides
    • 生产甘油二酯的方法
    • US20050214914A1
    • 2005-09-29
    • US10499819
    • 2002-12-27
    • Manabu SatoMasami ShimizuJun KohoriMinoru KaseTakaaki WatanabeKazuhiro Onozuka
    • Manabu SatoMasami ShimizuJun KohoriMinoru KaseTakaaki WatanabeKazuhiro Onozuka
    • C12P7/62C12P7/64
    • C12P7/6454C12P7/62
    • Provided is a preparation process of diglycerides which comprises reacting a fatty acid or lower alkyl ester thereof with glycerin in the presence of an immobilized partial glyceride lipase while removing water, which is generated upon reaction, out of the system. The reaction is preferably terminated when the acid value (AV) of the reaction mixture satisfies the following range: 50R-60>AV>70R-150 (with the proviso that AV>0). The present process makes it possible to efficiently prepare a high purity of diglycerides without impairing lipase activity even under reduced pressure. The present process is effective without being influenced by variations in reaction conditions such as fatty acid/glycerin ratio, reaction temperature or enzyme concentration. Particularly, even when the fatty acid/glycerin ratio is high, a high purity of diglycerides can be produced at a high reaction yield.
    • 提供了一种甘油二酯的制备方法,其包括在固定化的部分甘油酯脂肪酶的存在下使脂肪酸或其低级烷基酯与甘油反应,同时将反应后产生的水除去系统。 当反应混合物的酸值(AV)满足以下范围:50R-60> AV> 70R-150(条件是AV> 0)时,反应优选终止。 本方法使得即使在减压下也能有效地制备高纯度甘油二酯而不损害脂肪酶活性。 本方法不受脂肪酸/甘油比,反应温度或酶浓度等反应条件的变化的影响而有效。 特别是,即使脂肪酸/甘油的比例高,也能够以高的反应收率生产高纯度的甘油二酯。
    • 7. 发明授权
    • Process for the production of diglycerides
    • 生产甘油二酯的方法
    • US07141399B2
    • 2006-11-28
    • US10499819
    • 2002-12-27
    • Manabu SatoMasami ShimizuJun KohoriMinoru KaseTakaaki WatanabeKazuhiro Onozuka
    • Manabu SatoMasami ShimizuJun KohoriMinoru KaseTakaaki WatanabeKazuhiro Onozuka
    • C12P7/64
    • C12P7/6454C12P7/62
    • Provided is a preparation process of diglycerides which comprises reacting a fatty acid or lower alkyl ester thereof with glycerin in the presence of an immobilized partial glyceride lipase while removing water, which is generated upon reaction, out of the system. The reaction is preferably terminated when the acid value (AV) of the reaction mixture satisfies the following range: 50R-60>AV>70R-150 (with the proviso that AV>0). The present process makes it possible to efficiently prepare a high purity of diglycerides without impairing lipase activity even under reduced pressure. The present process is effective without being influenced by variations in reaction conditions such as fatty acid/glycerin ratio, reaction temperature or enzyme concentration. Particularly, even when the fatty acid/glycerin ratio is high, a high purity of diglycerides can be produced at a high reaction yield.
    • 提供了一种甘油二酯的制备方法,其包括在固定化的部分甘油酯脂肪酶的存在下使脂肪酸或其低级烷基酯与甘油反应,同时将反应后产生的水除去系统。 当反应混合物的酸值(AV)满足以下范围:50R-60> AV> 70R-150(条件是AV> 0)时,反应优选终止。 本方法使得即使在减压下也能有效地制备高纯度甘油二酯而不损害脂肪酶活性。 本方法不受脂肪酸/甘油比,反应温度或酶浓度等反应条件的变化的影响而有效。 特别是,即使脂肪酸/甘油的比例高,也能够以高的反应收率生产高纯度的甘油二酯。