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1. 发明授权

US4992451A 1,4-dihydropyridine derivatives 失效
标题翻译： 1,4-二氢吡啶衍生物
公开(公告)号：US4992451A
公开(公告)日：1991-02-12
申请号：US324981
申请日：1989-03-14
申请人： Hiroyuki Koike , Hiroshi Nishino , Masafumi Yoshimoto
发明人： Hiroyuki Koike , Hiroshi Nishino , Masafumi Yoshimoto
IPC分类号： A61K31/455 , A61K31/495 , A61P3/00 , A61P9/00 , A61P9/10 , A61P9/12 , C07D211/90
CPC分类号： C07D211/90
摘要： 1,4-Dihydro-6-methyl-4-(substituted phenyl)pyridine-3,5-dicarboxylic acid esters have an amino group at the 2-position and at least one nitrooxy group in at least one of the ester groups. These compounds have a variety of valuable activities, including antihypertensive and Ca.sup.++ -blocking activities, leading to their use for the treatment of circulatory and coronary disorders. They may be prepared by condensation of appropriate substituted acetic acid esters.
摘要翻译： 1,4-二氢-6-甲基-4-（取代苯基）吡啶-3,5-二羧酸酯在至少一个酯基中具有2-位的氨基和至少一个硝基氧基。这些化合物具有多种有价值的活性，包括抗高血压和Ca ++阻断活性，导致其用于治疗循环和冠状动脉疾病。它们可以通过合适的取代的乙酸酯的缩合来制备。

2. 发明授权

US4772596A Dihydropyridine derivatives, their preparation and their use 失效
标题翻译：二氢吡啶衍生物，其制备及其应用
公开(公告)号：US4772596A
公开(公告)日：1988-09-20
申请号：US105388
申请日：1987-10-05
申请人： Hiroyuki Koike , Hiroshi Nishino , Masafumi Yoshimoto
发明人： Hiroyuki Koike , Hiroshi Nishino , Masafumi Yoshimoto
IPC分类号： A61K31/455 , A61K31/4427 , A61P3/00 , A61P3/14 , A61P7/02 , A61P9/00 , A61P9/08 , A61P9/12 , C07D205/04 , C07D211/80 , C07D211/90 , C07D401/12 , C07D413/14 , A61K31/445
CPC分类号： C07D211/90 , C07D401/12
摘要： 2-(Amino or methyl)-6-(methyl or amino)-4-(substituted phenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid esters have a specific class of heterocyclic groups as thealcohol moiety. These compounds have a variety of valuable activities, including antihypertensive and Ca.sup.++ -blocking activities, leading to their use for the treatment of circulatory and coronary disorders. They may be prepared by condensation of appropriate substituted benzylideneacetoacetic acid esters with appropriate amidinoacetic acid esters.

3. 发明授权

US4426382A 4-Amino-6,7-dimethoxy-2-piperazinylquinazoline derivatives, their preparation and use 失效
标题翻译： 4-氨基-6,7-二甲氧基-2-哌嗪基喹唑啉衍生物，其制备和用途
公开(公告)号：US4426382A
公开(公告)日：1984-01-17
申请号：US233679
申请日：1981-02-11
申请人： Yasunobu Sato , Hiroshi Fukumi , Hiroyuki Koike , Hiroshi Nishino
发明人： Yasunobu Sato , Hiroshi Fukumi , Hiroyuki Koike , Hiroshi Nishino
IPC分类号： C07D239/95 , A61K31/505 , C07D403/04
CPC分类号： C07D239/95
摘要： Novel piperazinylquinazoline and homopiperazinylquinazoline compounds which have useful antihypertensive activity and their use including pharmaceutical compositions containing said derivatives as the active antihypertensive component thereof. Said compounds have the following formula. ##STR1## wherein m is 2 or 3 and R is as defined in the specification.
摘要翻译：具有有用的抗高血压活性的新型哌嗪基喹唑啉和高哌嗪基喹唑啉化合物及其用途，包括含有所述衍生物作为其主要抗高血压成分的药物组合物。所述化合物具有下式。其中m为2或3，R如说明书中所定义。

4. 发明授权

US5002942A 1,5-benzothiazepine derivatives, their preparation and their use in the treatment of cardiovascular disorders 失效
标题翻译： 1,5-苯并硫氮因衍生物，其制备及其在治疗心血管疾病中的应用
公开(公告)号：US5002942A
公开(公告)日：1991-03-26
申请号：US384261
申请日：1989-07-21
申请人： Hiroaki Yanagisawa , Koichi Fujimoto , Yasuo Shimoji , Takuro Kanazaki , Hiroyuki Koike , Hiroshi Nishino
发明人： Hiroaki Yanagisawa , Koichi Fujimoto , Yasuo Shimoji , Takuro Kanazaki , Hiroyuki Koike , Hiroshi Nishino
IPC分类号： C07D281/10 , C07D417/04 , C07D417/06
CPC分类号： C07D417/04 , C07D281/10 , C07D417/06
摘要： Compounds of formula (I): ##STR1## in which: R.sup.1 is aryl or aromatic heterocyclic; R.sup.2 and R.sup.3 are hydrogen, alkyl, alkoxy, halogen, phenyl, phenoxy, C.sub.1 -C.sub.6 alkylthio, phenylthio, C.sub.1 -C.sub.6 haloalkyl, cyano or nitro, or together are alkylene optionally containing oxygen; R.sup.4 is hydrogen, aliphatic acyl, cycloalkylcarbonyl, cycloalkoxycarbonyl, aromatic acyl, alkoxycarbonyl or benzyloxycarbonyl; R.sup.5 and R.sup.6 are alkyl; and X is oxygen, sulfur or methylene, have calcium channel blocking activity and can serve for the treatment or prophylaxis of cardiovascular diseases and disorders. They may be prepared by reacting a corresponding compound where R.sup.4 is hydrogen and the aminoethyl group is replaced by hydrogen with a compound providing the aminoethyl group and the, if required, acylating the product.

5. 发明授权

US5614542A Thiazolidine derivatives having anti-hypertensive activity and their therapeutic use 失效
标题翻译：具有抗高血压活性的噻唑烷衍生物及其治疗用途
公开(公告)号：US5614542A
公开(公告)日：1997-03-25
申请号：US456287
申请日：1995-05-31
申请人： Hiroyoshi Horikoshi , Toshihiko Fujiwara , Shinji Yoshioka , Hiroshi Nishino , Hiroyuki Koike , Takao Yoshioka
发明人： Hiroyoshi Horikoshi , Toshihiko Fujiwara , Shinji Yoshioka , Hiroshi Nishino , Hiroyuki Koike , Takao Yoshioka
IPC分类号： C07D417/12 , A61K31/425 , A61P3/04 , A61P3/08 , A61P9/12
CPC分类号： A61K31/425 , Y10S514/929
摘要： Thiazolidine derivatives of formula (I): ##STR1## (in which: R.sup.1, R.sup.2, R.sup.4, R.sup.5 are each hydrogen or alkyl; and R.sup.3 is hydrogen, aliphatic acyl, alkoxy-carbonyl, or arylcarbonyl and pharmaceutically acceptable salts thereof are anti-hypertensive agents and are useful in the treatment of obesity-related hypertension.
摘要翻译：式（I）的噻唑烷衍生物：其中：R 1，R 2，R 4，R 5各自为氢或烷基; R 3为氢，脂族酰基，烷氧羰基或芳基羰基及其药学上可接受的盐是抗高血压剂，可用于治疗肥胖相关性高血压。

6. 发明授权

US08492467B2 Automotive lamp peripheral parts 有权
标题翻译：汽车灯周边零件
公开(公告)号：US08492467B2
公开(公告)日：2013-07-23
申请号：US13320812
申请日：2010-05-21
申请人： Toru Yamaguchi , Hiroshi Kamo , Hiroshi Nishino , Hiroyuki Shinryu
发明人： Toru Yamaguchi , Hiroshi Kamo , Hiroshi Nishino , Hiroyuki Shinryu
IPC分类号： C08L71/12 , C08K3/34
CPC分类号： C08L71/08 , C08L25/04 , C08L53/025 , C08L71/02 , C08L71/12 , C08L2666/04 , C08L53/02
摘要： There is provided automotive lamp peripheral parts excellent in heat resistance, rigidity and fogging property. The lamp peripheral part according to the invention is obtained from a resin composition containing 70% by mass or more of a polyphenylene ether (A) and a styrene-based resin (B), and has a haze value of a glass plate of 1.0% or less after the glass plate is subjected to a fogging test using an apparatus according to ISO 6452.
摘要翻译：提供耐热性，刚性和起雾性优异的汽车灯周边部件。根据本发明的灯周边部分由含有70质量％以上的聚苯醚（A）和苯乙烯类树脂（B）的树脂组合物得到，玻璃板的雾度值为1.0％在使用根据ISO 6452的装置对玻璃板进行雾化试验之后，进行雾化试验。

7. 发明申请

US20070029530A1 Conductive resin composition and molded object 有权
标题翻译：导电性树脂组合物和成型体
公开(公告)号：US20070029530A1
公开(公告)日：2007-02-08
申请号：US10570272
申请日：2004-09-10
申请人： Kazuya Noda , Hiroshi Nishino , Norio Sakata
发明人： Kazuya Noda , Hiroshi Nishino , Norio Sakata
IPC分类号： H01B1/24
CPC分类号： C08L71/12 , C08K3/04 , C08K7/06 , C08L21/00 , C08L53/02 , C08L77/00 , C08L77/02 , C08L77/06 , C08L2205/03 , C08L2666/02 , C08L2666/24 , C08L2666/22
摘要： A conductive resin composition produced by melt-kneading a mixture comprising a polyamide (A), a polyphenylene ether (B) (non-terminal-modified polyphenylene ether and/or terminal-modified polyphenylene ether), a rubbery polymer (C), a conductive carbonaceous material (D) (carbon black and/or carbon fibril), and a low molecular weight modifier compound (E) (compatibility agent), wherein the mixture has the following characteristics: (1) the amount of (D) is 0.2 to 3% by weight, based on the total weight of (A) to (E), (2) the amount of (E) is more than 0.01% by weight and less than 0.20% by weight, based on the total weight of (A) to (E), and (3) the amount (a) of a volatile substance contained in (B) satisfies the following formula: 0≦a≦−7.3×E+1.83, wherein E is the % by weight of (E), based on the total weight of (A) to (E), the amount (a) being expressed in terms of a weight decrease (% by weight) of (B) as measured by subjecting (B) to vacuum drying in vacuo at 180 ° C. for 1 hour.
摘要翻译：通过将包含聚酰胺（A），聚苯醚（B）（非末端改性聚苯醚和/或末端改性聚苯醚）的混合物，橡胶状聚合物（C），导电碳质材料（D）（炭黑和/或碳原纤维）和低分子量改性剂化合物（E）（相容剂），其中该混合物具有以下特征：（1）（D）的量为0.2 以（A）〜（E）的总重为基准，（2）（E）的量为大于0.01重量％且小于0.20重量％，以总重量计为3重量％（A）〜（E），（3）（B）中所含的挥发性物质的量（a）满足下式：0 <= a <= 7.3×E + 1.83，其中E为重量％（E）中，（A）至（E）的总重量，（a）以（B）的真空度测定的（B）的重量减少（重量％）在180℃下真空干燥1小时你好

8. 发明授权

US6029501A Vibration type gas densitometer 有权
标题翻译：振动式气体密度计
公开(公告)号：US6029501A
公开(公告)日：2000-02-29
申请号：US194708
申请日：1998-12-15
申请人： Hiroshi Nishino , Junichi Suzuki , Shigeo Yasuda , Mitsuhiko Sasaki , Ryuichi Kawamura
发明人： Hiroshi Nishino , Junichi Suzuki , Shigeo Yasuda , Mitsuhiko Sasaki , Ryuichi Kawamura
IPC分类号： G01N9/00
CPC分类号： G01N9/002 , G01N2009/006
摘要： A vibration gas density meter provided with a cylindrical resonator, a cylinder block that incorporates the above cylindrical resonator concentrically and has one end of the cylindrical resonator fixed to itself, and a case which concentrically incorporates the above cylinder block and supports both ends of the cylinder block, further comprising first and second elastic elements which are provided between both end faces of the cylinder block and the case respectively, and through which the cylinder block is supported by the case in the direction of cylindrical axis, sealing the gaps between the cylinder block and the case as well, and third and fourth elastic elements which are provided between both parts of the outer cylindrical surface on both end face sides of the above cylinder block and the case respectively and through which the cylinder block is supported by the case in the radial direction, sealing the gaps between the cylinder block and the case as well.
摘要翻译： PCT No.PCT / JP98 / 01404 Sec。 371 1998年12月15日第 102（e）1998年12月15日日期PCT 1998年3月27日PCT PCT。第WO98 / 45681号公报日期：1998年10月15日具有圆柱形谐振器的振动气体密度计，包括上述圆柱形谐振器的圆柱体同心圆柱形谐振器固定在其自身上的气缸体，以及同心地并入上述气缸体和支撑件气缸体的两端还包括第一和第二弹性元件，其分别设置在气缸体的两个端面和壳体之间，并且气缸体由壳体沿着圆柱轴线的方向支撑，密封气缸体和壳体之间的间隙以及分别设置在上述气缸体的两个端面侧的外圆筒表面的两个部分和壳体之间并且气缸体被支撑的第三和第四弹性元件在径向的情况下，也密封气缸体和壳体之间的间隙。

9. 发明授权

US4976604A Pulse combustion apparatus 失效
标题翻译：脉冲燃烧装置
公开(公告)号：US4976604A
公开(公告)日：1990-12-11
申请号：US380770
申请日：1989-07-17
申请人： Hiroshi Nishino
发明人： Hiroshi Nishino
IPC分类号： F23L1/00 , F23C6/02 , F23C15/00
CPC分类号： F23C15/00 , F23C6/02
摘要： A pulse combustion apparatus comprises (i) a single air supply section with a single air blower and (ii) a plurality of combustion sections each communicating with the air supply section. The air supply section includes passages communicating with both the blower and the respective combustion sections for admitting air from the blower into the respective combustion sections. The air admitting passages are physically separated from each other for separating air from the blower into streams which are not able to join together anywhere.
摘要翻译：脉冲燃烧装置包括（i）具有单个鼓风机的单个空气供应部分和（ii）与空气供应部分连通的多个燃烧部分。空气供给部分包括与鼓风机和相应的燃烧部分相通的通道，用于将来自鼓风机的空气引入各个燃烧部分。空气进入通道在物理上彼此分离，以将空气从鼓风机分离成不能在任何地方连接在一起的流。

10. 发明授权

US4714569A Process for preparing conductive coating composition 失效
标题翻译：制备导电涂料组合物的方法
公开(公告)号：US4714569A
公开(公告)日：1987-12-22
申请号：US888196
申请日：1986-07-22
申请人： Hiroshi Nishino , Kazuo Okabe
发明人： Hiroshi Nishino , Kazuo Okabe
IPC分类号： C08F292/00 , C09D5/24 , H01B1/24 , H01B1/06
CPC分类号： H01B1/24 , C08F292/00 , C09D5/24
摘要： A process for preparing a conductive coating composition comprising the steps of forming a graft copolymer onto the surfaces of graphite and carbon black, adding an azo compound to the reaction system to complete the reaction, and curing the resulting product to form a network structure inside the product.
摘要翻译：一种制备导电涂料组合物的方法，包括以下步骤：在石墨和炭黑的表面上形成接枝共聚物，向反应体系中加入偶氮化合物以完成反应，并使所得产物固化以在其内部形成网络结构产品。

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