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    • 2. 发明授权
    • Placenta-derived anticoagulating substance, process for preparing same
and anticoagulant comprising same as an effective component
    • 胎盘衍生的抗凝物质,其制备方法和抗凝剂,其含有作为有效成分的抗凝血剂
    • US4732891A
    • 1988-03-22
    • US909296
    • 1986-09-19
    • Masahiro MakiHideo Tani
    • Masahiro MakiHideo Tani
    • A61K35/50A61K38/00A61K38/16A61P7/02C07K1/22C07K14/435C07K14/47C07K14/745C07K15/06A61K37/24
    • C07K14/4721A61K38/00G03C2001/0471Y10S530/842Y10S530/851
    • Novel human placenta-derived anticoagulating substances having the following properties:(1) molecular weight of 34,000.+-.2,000 determined by SDA-polyacrylamide gel electrphoresis under reduced state;(2) isoelectric point of 4.7.+-.0.1 determined by isoelectric column electrophoresis using an ampholite;(3) stabilityinactivated by heat treatment at 50.degree. C. to 30 minutes, stable at a pH of 4-10, and stable in plasma at 37.degree. C. for 30 minutes;(4) activitycapable of prolonging a recalcification time, a prothrombin time, and an activated partial thromboplastin time; and(5) the existence of several amino acids including aspartic acid, threonine, serine, and so on; are prepared by homogenizing human placenta, subjecting the resulting homogenate to centrifugal separation, extracting an anticoagulating substance from the residue or from a microsome fraction contained in the supernatant with a surface active agent and/or a chelating agent, and purifying and isolating the substance from the extract.The anticoagulating substances have a high anticoagulating activity and exhibit a higher activity in the state where the tissue thromboplastin activity is exacerbated or in the state of exacerbating the coagulation. Hence, the anticoagulant containing the substance as an effective component has reduced side effects and is thus harmless.
    • 具有以下性质的新型人胎盘抗凝物质:(1)在还原状态下通过SDA-聚丙烯酰胺凝胶电泳测定的分子量为34,000 +/- 2,000; (2)等电点为4.7 +/- 0.1,用等电点电泳法测定使用安培仑; (3)在50℃〜30分钟热处理稳定性稳定,pH值4-10时稳定,37℃下等离子体稳定30分钟; (4)能够延长再钙化时间,凝血酶原时间和活化部分凝血活酶时间的活性; 和(5)存在几种氨基酸,包括天冬氨酸,苏氨酸,丝氨酸等; 通过匀浆人胎盘,使所得匀浆离心分离,从残留物中提取抗凝物质或用表面活性剂和/或螯合剂从上清液中含有的微粒体部分提取抗体,并将其从 提取物。 抗凝物质具有高抗凝活性,在组织凝血激酶活性升高或凝血加重的状态下具有较高的活性。 因此,含有物质作为有效成分的抗凝剂具有减少的副作用,因此是无害的。
    • 5. 发明授权
    • Display device
    • 显示设备
    • US08164560B2
    • 2012-04-24
    • US12729530
    • 2010-03-23
    • Takayuki NakaoHideo SatoMasahiro MakiToshio Miyazawa
    • Takayuki NakaoHideo SatoMasahiro MakiToshio Miyazawa
    • G09G3/36
    • G09G3/3655
    • A display device is provided which includes a common electrode drive circuit having the single channel constitution which can miniaturize a circuit scale without increasing elements compared to a conventional display device. A display device includes a plurality of pixels and a common electrode drive circuit. The common electrode drive circuit includes a plurality of basic circuits, wherein the basic circuit includes a first circuit which latches a first input signal at a point of time that a clock signal is changed to a first voltage level from a second voltage level; a second circuit which latches a second input signal at the point of time that the clock signal is changed to the first voltage level from the second voltage level; a first switching circuit which is turned on based on the first circuit and a second switching circuit which is turned on based on the second circuit.
    • 提供一种显示装置,其包括具有单通道结构的公共电极驱动电路,其可以与传统的显示装置相比能够使电路规模小型化而不增加元件。 显示装置包括多个像素和公共电极驱动电路。 公共电极驱动电路包括多个基本电路,其中基本电路包括第一电路,其在时钟信号从第二电压电平变为第一电压电平的时间点锁存第一输入信号; 第二电路,其在时钟信号从第二电压电平改变为第一电压电平的时间点锁存第二输入信号; 基于第一电路接通的第一开关电路和基于第二电路导通的第二开关电路。
    • 9. 发明授权
    • Display device
    • 显示设备
    • US07724231B2
    • 2010-05-25
    • US11384363
    • 2006-03-21
    • Takayuki NakaoHideo SatoMasahiro MakiToshio Miyazawa
    • Takayuki NakaoHideo SatoMasahiro MakiToshio Miyazawa
    • G09G3/36
    • G09G3/3655
    • The present invention provides a display device which includes a common electrode drive circuit having the single channel constitution which can miniaturize a circuit scale without increasing elements compared to a conventional display device. A display device includes a plurality of pixels and a common electrode drive circuit. The common electrode drive circuit includes a plurality of basic circuits, wherein the basic circuit includes a first circuit which latches a first input signal at a point of time that a clock signal is changed to a first voltage level from a second voltage level; a second circuit which latches a second input signal at the point of time that the clock signal is changed to the first voltage level from the second voltage level; a first switching circuit which is turned on based on the first circuit; and a second switching circuit which is turned on based on the the second circuit.
    • 本发明提供了一种显示装置,其包括具有单通道结构的公共电极驱动电路,其可以与常规显示装置相比能够使电路规模小型化而不增加元件。 显示装置包括多个像素和公共电极驱动电路。 公共电极驱动电路包括多个基本电路,其中基本电路包括第一电路,其在时钟信号从第二电压电平变为第一电压电平的时间点锁存第一输入信号; 第二电路,其在时钟信号从第二电压电平改变为第一电压电平的时间点锁存第二输入信号; 基于第一电路接通的第一开关电路; 以及基于第二电路接通的第二开关电路。
    • 10. 发明授权
    • Display device having an improved voltage level converter circuit
    • 显示装置具有改进的电压电平转换器电路
    • US07545357B2
    • 2009-06-09
    • US11203971
    • 2005-08-16
    • Toshio MiyazawaHideo SatouTomohiko SatouMasahiro Maki
    • Toshio MiyazawaHideo SatouTomohiko SatouMasahiro Maki
    • G09G3/36H03L5/00H03K19/0175
    • H03K5/003G09G3/3648G09G2300/0408G09G2310/0289G09G2330/02H03K19/0013H03K19/018571
    • A display device has a driver including a level converter formed of polysilicon MISTFTs. The level converter includes first, second and third N-channel MISTFTs (NMISTFTS) and first, second and third P-channel MISTFTs (PMISTFTS). Gate and first terminals of the first NMISTFT and PMISTFT, and a gate terminal of the third PMISTFT are coupled to an input terminal via a capacitance. Second terminals of the second NMISTFT and PMISTFT, and a gate terminal of third NMISTFT are coupled to the input terminal via a capacitance. A first terminal of the third PMISTFT, and second terminals of the first NMISTFT and PMISTFT are coupled to a high voltage. A second terminal of the third NMISTFT, gate and first terminals of the second NMISTFT and PMISTFT are coupled to a low voltage. A second terminal of the third PMISTFT and a first terminal of the third NMISTFT are connected to an output terminal.
    • 显示装置具有包括由多晶硅MISTFT形成的电平转换器的驱动器。 电平转换器包括第一,第二和第三N信道MISTFT(NMISTFTS)和第一,第二和第三P信道MISTFT(PMISTFTS)。 第一NMISTFT和PMISTFT的栅极和第一端子以及第三PMISTFT的栅极端子经由电容耦合到输入端子。 第二NMISTFT和PMISTFT的第二端子和第三NMISTFT的栅极端子经由电容耦合到输入端子。 第三PMISTFT的第一端子和第一NMISTFT和PMISTFT的第二端子耦合到高电压。 第三NMISTFT的第二端子,第二NMISTFT和PMISTFT的栅极和第一端子耦合到低电压。 第三PMISTFT的第二端子和第三NMISTFT的第一端子连接到输出端子。