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    • 4. 发明授权
    • Atmospheric pressure ionization mass spectrometer
    • 大气压电离质谱仪
    • US5485016A
    • 1996-01-16
    • US231847
    • 1994-04-25
    • Takashi IrieYasuhiro MitsuiKazuaki MizokamiKatsumi Kuriyama
    • Takashi IrieYasuhiro MitsuiKazuaki MizokamiKatsumi Kuriyama
    • G01N27/62H01J49/04H01J49/10H01J49/26
    • H01J49/168H01J49/0422H01J49/145
    • A mass spectrometer for analyzing trace impurities on a level between ppt and ppb contained in silicon material gas such as monosilane gas. The mass spectrometer includes an ion formation region, reaction region, and mass analysis region. Ion formation gas is introduced into the ion formation region and sample gas (silicon material gas) is introduced into the reaction region. The ion formation region ionizes ion formation gas by an ionizer and forms primary ions. When the pressure of ion formation gas is made higher than the pressure of sample gas, the ion formation gas flows into the reaction region from the ion formation region together with primary ions and is mixed with the sample gas. In the reaction region, an ion-molecule reaction is produced between the primary ions and trace impurities contained in the sample gas and the trace impurities contained in the sample gas are ionized. The ion intensity of trace impunities, the concentration of trace impurities in the sample gas is determined using a calibration curve. When the gas pressure in the reaction region is kept at almost 1 atmosphere, the reaction is promoted and when the ion-molecule reaction time is optimized according to the size of the reaction region and the voltage condition, impurities on a level between ppt and ppb can be detected and determined.
    • 用于分析硅材料气体(如硅烷气体)中含有的ppt和ppb之间的痕量杂质的质谱仪。 质谱仪包括离子形成区域,反应区域和质量分析区域。 将离子形成气体引入离子形成区域,并将样品气体(硅材料气体)引入反应区域。 离子形成区域通过离子发生器离子化形成气体并形成初级离子。 当离子形成气体的压力高于样品气体的压力时,离子形成气体与一次离子一起从离子形成区域流入反应区域,并与样品气体混合。 在反应区域中,在原料离子和样品气体中含有的微量杂质之间产生离子分子反应,并将样品气体中所含的痕量杂质离子化。 使用校准曲线确定痕量缺陷的离子强度,样品气体中微量杂质的浓度。 当反应区域的气体压力保持在大致1气道时,促进反应,当根据反应区域的大小和电压条件优化离子分子反应时间时,ppt与ppb之间的杂质 可以被检测和确定。
    • 5. 发明授权
    • Navigation system
    • 导航系统
    • US08825372B2
    • 2014-09-02
    • US13131134
    • 2009-10-29
    • Kumi NishibashiTakashi Irie
    • Kumi NishibashiTakashi Irie
    • G01C21/26G01C21/32G01C21/34
    • G01C21/34G01C21/3629G01C21/3658G09B29/007G09B29/10
    • A navigation system includes: a map information acquiring unit 31 for acquiring map information; an HOV lane decision unit 38 for deciding whether an HOV lane is included in a road represented by the map information acquired by the map information acquiring unit 31 or not; a road number processing unit 43 for performing, when the HOV lane decision unit 38 decides that the HOV lane is included, processing of adding information representing the HOV lane to a road number of the road including the HOV lane; and a display processing unit 44 or a voice information unit 46 for causing the road number passing through the processing by the road number processing unit 43 to be displayed on the guide map or output in voice.
    • 导航系统包括:地图信息获取单元31,用于获取地图信息; HOV车道判定单元38,用于判定由地图信息获取单元31获取的地图信息表示的道路中是否包括HOV车道; 道路号处理单元43,用于当HOV车道判定单元38判定包括HOV车道时,执行表示HOV车道的信息到包括HOV车道的道路的道路号码的处理; 以及用于使通过道路号码处理单元43的处理的道路号码显示在引导地图上或以语音输出的显示处理单元44或语音信息单元46。
    • 9. 发明申请
    • Fluorescence analyzing method, fluorescence analyzing apparatus and image detecting method
    • 荧光分析方法,荧光分析装置和图像检测方法
    • US20070281315A1
    • 2007-12-06
    • US11806318
    • 2007-05-31
    • Satoshi TakahashiTakashi Irie
    • Satoshi TakahashiTakashi Irie
    • C12Q1/68G06F19/00C12M3/00
    • G01N21/6452
    • A fluorescence analyzing method includes the steps of irradiating a board, to which oligonucleotide is fixed, with light for fluorescence measurement; focusing produced fluorescence to form an image; and detecting the fluorescence with a two-dimensional sensor. Here, the board is provided with plural regions to which the oligonucleotide is fixed, and the plural regions are spaced apart from one another on the board substantially equidistantly in the vertical and horizontal directions. A fluorescent image is detected in a condition where the following equation is satisfied: dd=ds×M/n where ds denotes the interval between the regions, M denotes the imaging magnification of an optical focusing/imaging system, dd denotes the pixel pitch of the two-dimensional sensor, and n denotes an integer (n=1, 2, 3, 4, 5).
    • 荧光分析方法包括以下步骤:将固定有寡核苷酸的板与用于荧光测量的光照射; 聚焦产生荧光以形成图像; 并用二维传感器检测荧光。 这里,板上设置有寡核苷酸固定的多个区域,并且多个区域在基板上基本等距离地在垂直和水平方向上彼此间隔开。 在满足以下等式的条件下检测荧光图像:<?in-line-formula description =“In-line formula”end =“lead”?> dd = dsxM / n <?in-line-formula description =“在线公式”end =“tail”?>其中ds表示区域之间的间隔,M表示光学聚焦/成像系统的成像倍率,dd表示二维传感器的像素间距,n表示 表示整数(n = 1,2,3,4,5)。
    • 10. 发明授权
    • PCR primers and a method for deciding a base sequence thereof regarding adenylation
    • PCR引物和用于确定其关于腺苷酸化的碱基序列的方法
    • US06773901B2
    • 2004-08-10
    • US10083616
    • 2002-02-27
    • Chihiro UematsuKazunori OkanoTakashi Irie
    • Chihiro UematsuKazunori OkanoTakashi Irie
    • C12P1934
    • C12Q1/6853C12Q2525/161
    • Adenylation of a DNA fragment with a DNA polymerase occurs in the course of PCR, and thus two peaks are detected. To prevent the peak splitting, it is necessary to raise efficiency of adenylation a single peak to occur without changing reaction conditions. To this end, four types of PCR primers which, respectively, have an anchor sequence at 5′ terminus so that any of A, C, G or T is attached to at the 5′ terminus of the anchor sequence, and PCR is carried out by use of the respective primers to determine efficiencies of adenylation. Subsequently, an anchor sequence that is more likely to undergo adenylation is screened to decide an anchor sequence more likely undergo adenylation, followed by PCR by use of a primer having the decided anchor sequence.
    • 在PCR过程中DNA聚合酶的DNA片段的腺苷酸化发生,因此检测到两个峰。 为了防止峰分裂,需要提高腺苷酸化的效率,单峰发生而不改变反应条件。 为此,分别在5'末端具有锚定序列以使A,C,G或T中的任一个连接到锚定序列的5'末端的4种PCR引物,并进行PCR 通过使用各自的引物来确定腺苷酸化的效率。 随后,筛选更可能进行腺苷酸化的锚定序列以确定锚定序列更可能进行腺苷酸化,随后通过使用具有决定的锚定序列的引物进行PCR。