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1. 发明授权

US07951825B2 Hetero compound 有权
标题翻译：杂环化合物
公开(公告)号：US07951825B2
公开(公告)日：2011-05-31
申请号：US12696327
申请日：2010-01-29
申请人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Masataka Morita , Sunao Imada , Yoshito Abe , Hiromichi Itani , Tatsuaki Morokata , Hideo Tsutsumi
发明人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Masataka Morita , Sunao Imada , Yoshito Abe , Hiromichi Itani , Tatsuaki Morokata , Hideo Tsutsumi
IPC分类号： C07D413/02 , C07D413/14 , C07D401/02 , C07D401/14 , A61K31/443
CPC分类号： C07D413/04 , C07D417/04 , C07D471/04
摘要： To provide a useful compound as an active ingredient for a preventing and/or treating agent for rejection in the transplantation of an organ, bone marrow, or a tissue, an autoimmune disease, or the like, which has an excellent S1P1 agonist activity.Since the compound of the invention has an S1P1 agonist activity, it is useful as an active ingredient for a treating or preventing agent for a disease caused by unfavorable lymphocytic infiltration, for example, an autoimmune disease such as graft rejection in the transplantation of an organ, bone marrow, or a tissue, a graft-versus-host disease, rheumatic arthritis, multiple sclerosis, systemic lupus erythematosus, a nephrotic syndrome, encephalomeningitis, myasthenia gravis, pancreatitis, hepatitis, nephritis, diabetes, pulmonary disorder, asthma, atopic dermatitis, inflammatory bowel disease, atherosclerosis, ischemia-reperfusion injury, or an inflammatory disease, and further, a disease caused by the abnormal growth or accumulation of cells such as cancer and leukemia.
摘要翻译：为了提供具有优异的S1P1激动剂活性的器官，骨髓或组织，自身免疫疾病等的移植中的预防和/或治疗剂的有效成分的有用化合物。由于本发明的化合物具有S1P1激动剂活性，因此可用作治疗或预防由不利淋巴细胞浸润引起的疾病的活性成分，例如自体免疫疾病例如器官移植中的移植排斥反应骨髓或组织，移植物抗宿主病，风湿性关节炎，多发性硬化症，系统性红斑狼疮，肾病综合征，脑炎，重症肌无力，胰腺炎，肝炎，肾炎，糖尿病，肺病，哮喘，特应性皮炎炎症性肠病，动脉粥样硬化，缺血再灌注损伤或炎性疾病，以及由细胞如癌症和白血病的异常生长或积累引起的疾病。

2. 发明授权

US07678820B2 Hetero compound 有权
标题翻译：杂环化合物
公开(公告)号：US07678820B2
公开(公告)日：2010-03-16
申请号：US12244102
申请日：2008-10-02
申请人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Masataka Morita , Sunao Imada , Yoshito Abe , Hiromichi Itani , Tatsuaki Morokata , Hideo Tsutsumi
发明人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Masataka Morita , Sunao Imada , Yoshito Abe , Hiromichi Itani , Tatsuaki Morokata , Hideo Tsutsumi
IPC分类号： A61K31/4245 , C07D271/06
CPC分类号： C07D413/04 , C07D417/04 , C07D471/04
摘要： To provide a useful compound as an active ingredient for a preventing and/or treating agent for rejection in the transplantation of an organ, bone marrow, or a tissue, an autoimmune disease, or the like, which has an excellent S1P1 agonist activity. Since the compound of the invention has an S1P1 agonist activity, it is useful as an active ingredient for a treating or preventing agent for a disease caused by unfavorable lymphocytic infiltration, for example, an autoimmune disease such as graft rejection in the transplantation of an organ, bone marrow, or a tissue, a graft-versus-host disease, rheumatic arthritis, multiple sclerosis, systemic lupus erythematosus, a nephrotic syndrome, encephalomeningitis, myasthenia gravis, pancreatitis, hepatitis, nephritis, diabetes, pulmonary disorder, asthma, atopic dermatitis, inflammatory bowel disease, atherosclerosis, ischemia-reperfusion injury, or an inflammatory disease, and further, a disease caused by the abnormal growth or accumulation of cells such as cancer and leukemia.
摘要翻译：为了提供具有优异的S1P1激动剂活性的器官，骨髓或组织，自身免疫疾病等的移植中的预防和/或治疗剂的有效成分的有用化合物。由于本发明的化合物具有S1P1激动剂活性，因此可用作治疗或预防由不利淋巴细胞浸润引起的疾病的活性成分，例如自体免疫疾病例如器官移植中的移植排斥反应骨髓或组织，移植物抗宿主病，风湿性关节炎，多发性硬化症，系统性红斑狼疮，肾病综合征，脑炎，重症肌无力，胰腺炎，肝炎，肾炎，糖尿病，肺病，哮喘，特应性皮炎炎症性肠病，动脉粥样硬化，缺血再灌注损伤或炎性疾病，以及由细胞如癌症和白血病的异常生长或积累引起的疾病。

3. 发明申请

US20100168159A1 HETERO COMPOUND 有权
标题翻译： HETERO化合物
公开(公告)号：US20100168159A1
公开(公告)日：2010-07-01
申请号：US12696327
申请日：2010-01-29
申请人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Masataka Morita , Sunao Imada , Yoshito Abe , Hiromichi Itani , Tatsuaki Morokata , Hideo Tsutsumi
发明人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Masataka Morita , Sunao Imada , Yoshito Abe , Hiromichi Itani , Tatsuaki Morokata , Hideo Tsutsumi
IPC分类号： A61K31/4439 , A61K31/4709 , C07D471/04 , C07D413/14 , A61P35/02 , A61P37/06 , A61P29/00 , A61P9/10 , A61P35/00
CPC分类号： C07D413/04 , C07D417/04 , C07D471/04
摘要： [Problems]To provide a useful compound as an active ingredient for a preventing and/or treating agent for rejection in the transplantation of an organ, bone marrow, or a tissue, an autoimmune disease, or the like, which has an excellent S1P1 agonist activity.[Means for solving]Since the compound of the invention has an S1P1 agonist activity, it is useful as an active ingredient for a treating or preventing agent for a disease caused by unfavorable lymphocytic infiltration, for example, an autoimmune disease such as graft rejection in the transplantation of an organ, bone marrow, or a tissue, a graft-versus-host disease, rheumatic arthritis, multiple sclerosis, systemic lupus erythematosus, a nephrotic syndrome, encephalomeningitis, myasthenia gravis, pancreatitis, hepatitis, nephritis, diabetes, pulmonary disorder, asthma, atopic dermatitis, inflammatory bowel disease, atherosclerosis, ischemia-reperfusion injury, or an inflammatory disease, and further, a disease caused by the abnormal growth or accumulation of cells such as cancer and leukemia.
摘要翻译： [问题]提供一种有用的化合物作为活性成分，用于预防和/或治疗移植器官，骨髓或组织，自身免疫疾病等中的排斥反应，其具有优异的S1P1激动剂活动。 [解决方法]由于本发明的化合物具有S1P1激动剂活性，因此可用作由不利的淋巴细胞浸润引起的疾病的治疗或预防剂的活性成分，例如自身免疫性疾病如移植排斥反应器官移植，骨髓或组织，移植物抗宿主病，风湿性关节炎，多发性硬化，系统性红斑狼疮，肾病综合征，脑炎，重症肌无力，胰腺炎，肝炎，肾炎，糖尿病，肺功能障碍哮喘，特应性皮炎，炎症性肠病，动脉粥样硬化，局部缺血再灌注损伤，炎症性疾病等疾病，以及癌症，白血病等细胞异常生长或积累引起的疾病。

4. 发明申请

US20120178735A1 2H-CHROMENE COMPOUND AND DERIVATIVE THEREOF 审中-公开
标题翻译： 2H-氯化合物及其衍生物
公开(公告)号：US20120178735A1
公开(公告)日：2012-07-12
申请号：US13396861
申请日：2012-02-15
申请人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Sunao Imada , Tatsuaki Morokata
发明人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Sunao Imada , Tatsuaki Morokata
IPC分类号： A61K31/4025 , A61K31/397 , A61K31/427 , A61P29/00 , A61K31/444 , A61K31/5377 , A61K31/497 , A61P37/06 , A61K31/453 , A61K31/4155
CPC分类号： C07D403/12 , C07D405/06 , C07D405/14 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14
摘要： Provided is a 2H-chromene compound or a derivative thereof which has an excellent S1P1 agonist action. The 2H-chromene compound or derivative is particularly useful for preventing and/or treating a disease induced by undesirable lymphocyte infiltration or a disease induced by abnormal proliferation or accumulation of cells.
摘要翻译：提供具有优异的S1P1激动剂作用的2H-色烯化合物或其衍生物。 2H-色烯化合物或衍生物特别可用于预防和/或治疗由不希望的淋巴细胞浸润引起的疾病或由细胞的异常增殖或积聚引起的疾病。

5. 发明授权

US08193378B2 2H-chromene compound and derivative thereof 有权
标题翻译： 2H-色烯化合物及其衍生物
公开(公告)号：US08193378B2
公开(公告)日：2012-06-05
申请号：US13131343
申请日：2009-12-04
申请人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Sunao Imada , Tatsuaki Morokata
发明人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Sunao Imada , Tatsuaki Morokata
IPC分类号： C07D311/00
CPC分类号： C07D403/12 , C07D405/06 , C07D405/14 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14
摘要： Provided is a compound which has an excellent S1P1 agonist action, and is useful particularly as an active ingredient for an agent for preventing and/or treating a disease induced by undesirable lymphocyte infiltration or a disease induced by abnormal proliferation or accumulation of cells. According to the present invention, a 2H-chromene compound or a derivative thereof which has an excellent S1P1 agonist action, and is useful particularly as an active ingredient of an agent for preventing and/or treating a disease induced by undesirable lymphocyte infiltration or a disease induced by abnormal proliferation or accumulation of cells can be provided. The 2H-chromene compound and a derivative thereof which are the compounds of the present invention have an S1P1 agonist action, and can be used particularly for prevention and/or treatment of a disease induced by undesirable lymphocyte infiltration or a disease induced by abnormal proliferation or accumulation of cells.
摘要翻译：本发明提供了具有优异的S1P1激动剂作用的化合物，特别是用于预防和/或治疗由不希望的淋巴细胞浸润引起的疾病或由细胞的异常增殖或积聚引起的疾病的活性成分。根据本发明，具有优异的S1P1激动剂作用的2H-色烯化合物或其衍生物，并且特别用作预防和/或治疗由不想要的淋巴细胞浸润或疾病引起的疾病的药剂的活性成分可以提供异常增殖或细胞积聚诱导的细胞。作为本发明化合物的2H-色烯化合物及其衍生物具有S1P1激动剂作用，可以特别用于预防和/或治疗由不想要的淋巴细胞浸润引起的疾病或由异常增殖诱导的疾病或细胞积聚。

6. 发明申请

US20110230463A1 2H-CHROMENE COMPOUND AND DERIVATIVE THEREOF 有权
标题翻译： 2H-氯化合物及其衍生物
公开(公告)号：US20110230463A1
公开(公告)日：2011-09-22
申请号：US13131343
申请日：2009-12-04
申请人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Sunao Imada , Tatsuaki Morokata
发明人： Hironori Harada , Kazuyuki Hattori , Kazuya Fujita , Sunao Imada , Tatsuaki Morokata
IPC分类号： A61K31/397 , C07D405/06 , A61K31/4025 , C07D417/14 , A61K31/428 , A61K31/453 , C07D405/14 , A61K31/404 , C07D409/14 , A61K31/427 , A61K31/4155 , A61K31/4433 , C07D311/58 , A61K31/352 , A61P29/00 , A61P37/06 , A61P25/28
CPC分类号： C07D403/12 , C07D405/06 , C07D405/14 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14
摘要： [Object] Provided is a compound which has an excellent S1P1 agonist action, and is useful particularly as an active ingredient for an agent for preventing and/or treating a disease induced by undesirable lymphocyte infiltration or a disease induced by abnormal proliferation or accumulation of cells.[Means for Solution] According to the present invention, a 2H-chromene compound or a derivative thereof which has an excellent S1P1 agonist action, and is useful particularly as an active ingredient of an agent for preventing and/or treating a disease induced by undesirable lymphocyte infiltration or a disease induced by abnormal proliferation or accumulation of cells can be provided. The 2H-chromene compound and a derivative thereof which are the compounds of the present invention have an S1P1 agonist action, and can be used particularly for prevention and/or treatment of a disease induced by undesirable lymphocyte infiltration or a disease induced by abnormal proliferation or accumulation of cells.
摘要翻译：本发明提供具有优异的S1P1激动剂作用的化合物，特别是用于预防和/或治疗由不希望的淋巴细胞浸润引起的疾病或由细胞的异常增殖或积聚引起的疾病的活性成分。 [解决方案]根据本发明，具有优异的S1P1激动剂作用的2H-色烯化合物或其衍生物，特别是作为用于预防和/或治疗由不希望的可以提供淋巴细胞浸润或由细胞的异常增殖或积聚诱导的疾病。作为本发明化合物的2H-色烯化合物及其衍生物具有S1P1激动剂作用，可以特别用于预防和/或治疗由不想要的淋巴细胞浸润引起的疾病或由异常增殖诱导的疾病或细胞积聚。

7. 发明授权

US09628644B2 Controller for imaging terminal 有权
公开(公告)号：US09628644B2
公开(公告)日：2017-04-18
申请号：US14039879
申请日：2013-09-27
申请人： Hironori Harada , Kanae Tamura , Kan Ishimoto , Yusuke Kida
发明人： Hironori Harada , Kanae Tamura , Kan Ishimoto , Yusuke Kida
IPC分类号： H04N1/00 , G06K9/00 , H04N1/32
CPC分类号： H04N1/00408 , G06F9/453 , G06F17/30247 , G06F17/30256 , G06K9/00624 , G06K9/00671 , H04N1/00037 , H04N1/00039 , H04N1/00058 , H04N1/00066 , H04N1/0035 , H04N1/00424 , H04N1/00427 , H04N1/00435 , H04N1/00464 , H04N1/00477 , H04N1/32 , H04N1/32625 , H04N1/32651
摘要： A controller for an imaging terminal having an imaging device and a first displaying device includes a processor and a memory. The memory stores instructions, when executed by the processor, causing the processor to perform: acquiring shot image data, the shot image data being obtained by shooting a second displaying device which is a part of an apparatus, the apparatus being a target device to be shot, the second displaying device being configured to display a specific state image indicative of a current state of the apparatus; acquiring, by analyzing the shot image data, specific identification information for identifying specific relevant information associated with the specific state image; acquiring the specific relevant information by using the specific identification information; and controlling the first displaying device to display the specific relevant information.

8. 发明申请

US20150171409A1 SEALED BATTERY 审中-公开
标题翻译：密封电池
公开(公告)号：US20150171409A1
公开(公告)日：2015-06-18
申请号：US14405672
申请日：2013-07-16
申请人： Akira Kiyama , Toshihiro Takada , Hiroshi Inukai , Hironori Harada , Yasushi Tsuchida
发明人： Akira Kiyama , Toshihiro Takada , Hiroshi Inukai , Hironori Harada , Yasushi Tsuchida
IPC分类号： H01M2/30 , H01M2/34 , H01M2/36
CPC分类号： H01M2/30 , H01M2/34 , H01M2/345 , H01M2/365 , H01M10/0525
摘要： A sealed battery includes a battery case, an external terminal, a collector terminal, a protruding member, and a pressure type current interrupting mechanism. The pressure type current interrupting mechanism electrically disconnects the external terminal from the collector terminal by an inverted plate deforming according to an increase in pressure inside the battery case. The protruding member has a through-hole that is communicated with a hollow portion of the external terminal. When the pressure type current interrupting mechanism is activated, the protruding member pierces the inverted plate, such that the hollow portion of the external terminal is communicated with the inside of the battery case further inside the battery case than the collector terminal of the battery case, via the through-hole of the protruding member.
摘要翻译：密封电池包括电池壳体，外部端子，集电极端子，突出部件和压力型电流中断机构。压力型电流中断机构根据电池壳体内的压力增加，通过倒置板变形将外部端子与集电极端子电连接。突出部件具有与外部端子的中空部连通的通孔。当压力型电流中断机构被激活时，突出部件穿透反转板，使得外部端子的中空部分比电池壳体的集电器端子进一步与电池壳体的内部进一步连通，通过突出构件的通孔。

9. 发明授权

US08274262B2 Electric vehicle having a secondary battery and a method of charging and recharging the secondary battery 有权
标题翻译：具有二次电池的电动车辆和对二次电池进行充电和再充电的方法
公开(公告)号：US08274262B2
公开(公告)日：2012-09-25
申请号：US12451355
申请日：2008-06-30
申请人： Hironori Harada
发明人： Hironori Harada
IPC分类号： H01M10/44 , H01M10/46
CPC分类号： H01M10/44 , B60L1/02 , B60L11/1861 , H01M10/0525 , H01M10/48 , Y02E60/122 , Y02T10/7005 , Y02T10/7044 , Y02T10/705
摘要： An electric vehicle includes a secondary battery which performs charge from an external power source and travels by using power of the secondary battery. The electric vehicle further includes: a charging unit which charges the secondary battery with power supplied by connecting a charge plug to the external power source; and a control unit which performs information acquisition or control for respective constituent elements. The control unit acquires a remaining capacity value from the secondary battery upon charge. When the control unit judges that a high charge capacity state continues a predetermined number of times, the control unit performs charge up to a charge capacity lower than a full electric capacity amount. This can suppress degradation of the secondary battery by charge.
摘要翻译：电动车辆包括从外部电源进行充电并通过使用二次电池的电力行进的二次电池。电动车还包括：充电单元，其通过将充电插头连接到外部电源而供给的电力对二次电池充电; 以及对各构成要素执行信息获取或控制的控制单元。控制单元在充电时从二次电池获取剩余容量值。当控制单元判定高充电容量状态持续预定次数时，控制单元执行充电至低于全电容量的充电容量。这可以通过充电来抑制二次电池的劣化。

10. 发明授权

US07686527B2 Tape printing device and tape cassette 有权
公开(公告)号：US07686527B2
公开(公告)日：2010-03-30
申请号：US11518143
申请日：2006-09-11
申请人： Hironori Harada , Yoshihito Nonomura
发明人： Hironori Harada , Yoshihito Nonomura
IPC分类号： B41J11/00
CPC分类号： B41J11/0095 , B41J3/4075 , B41J11/009 , B41J11/46 , B41J11/703 , B41J15/044
摘要： When a label tape 36 after the printing on a label 39 has been fed to a tape cutting position, heating elements R1-Rn of a thermal head 9 is situated to face a position slightly on the upstream side of a label front end position (at the downstream end in the feeding direction) of the next label 39 which will be printed on next and to face a position on the downstream side of a print start position of the next label 39 (a

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