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1. 发明授权

US4009206A N-(substituted phenyl and benzyl)abietamides 失效
标题翻译： N-（取代苯基和苯甲基）亚胺
公开(公告)号：US4009206A
公开(公告)日：1977-02-22
申请号：US604308
申请日：1975-08-13
申请人： Hiromu Murai , Katsuya Ohata , Hiroshi Enomoto , Kenji Sempuku , Koji Kitaguchi , Yukio Fujita , Yoshiaki Yoshikuni , Kohei Kura , Katsahide Saito , Tamiki Mori , Yasuo Yasutomi
发明人： Hiromu Murai , Katsuya Ohata , Hiroshi Enomoto , Kenji Sempuku , Koji Kitaguchi , Yukio Fujita , Yoshiaki Yoshikuni , Kohei Kura , Katsahide Saito , Tamiki Mori , Yasuo Yasutomi
IPC分类号： A61K31/16 , A61K31/19 , A61K31/215 , C07C20060101 , C07C101/18 , C07C101/453 , C07C103/19
CPC分类号： C07C2103/26
摘要： Substituted N-phenyl and N-benzyl abietamide derivatives, including the dehydro-, dihydro-, and tetrahydroabietamide derivatives, are cholesterol lowering agents. The abietamide derivatives, of which N-(2,6-dimethylphenyl)-.DELTA..sup.8 -dihydroabietamide is a typical example, are produced by the reaction of abietic acid, dehydroabietic acid, dihydroabietic acid, tetrahydroabietic acid and/or active derivatives thereof with a substituted aniline or benzylamine.

2. 发明授权

US4210671A Abietamide derivatives, their production and use 失效
标题翻译：安息香酰胺衍生物，其生产和使用
公开(公告)号：US4210671A
公开(公告)日：1980-07-01
申请号：US576303
申请日：1975-05-12
申请人： Hiromu Murai , Katsuya Ohata , Hiroshi Enomoto , Kenji Sempuku , Koji Kitaguchi , Yukio Fujita , Yoshiaki Yoshikuni , Kohei Kura , Katsuhide Saito , Tamiki Mori , Yasuo Yasutomi
发明人： Hiromu Murai , Katsuya Ohata , Hiroshi Enomoto , Kenji Sempuku , Koji Kitaguchi , Yukio Fujita , Yoshiaki Yoshikuni , Kohei Kura , Katsuhide Saito , Tamiki Mori , Yasuo Yasutomi
IPC分类号： A61K31/16 , A61K31/165 , C07C67/00 , C07C231/00 , C07C231/02 , C07C233/00 , C07C233/38 , C07C233/58
CPC分类号： C07C233/00 , C07C2103/26
摘要： A process for the preparation of amide derivatives of abietic acid, dehydroabietic acid, dihydroabietic acid or tetrahydroabietic acid which comprises reacting abietic acid, dehydroabietic acid, dihydroabietic acid or tetrahydroabietic acid or a reactive derivative thereof with an amine of the following formula:HNRR'wherein R and R' are each hydrogen, a straight chain or branched alkyl group having 3 to 15 carbon atoms, a lower alkenyl group, a cycloalkyl group, a phenyl group, a phenylalkyl group and a phenylalkyl group having a lower alkyl group at the .alpha.-position, with the proviso that such amines where both R and R' are hydrogen or where one of R and R' is hydrogen and the other is phenyl are excluded.The invention further comprises the resulting abietamide derivative reaction products, compositions containing effective blood serum cholesterol-reducing amounts of said abietamide derivatives and their use as anti-arteriosclerotic agents.
摘要翻译：制备松香酸，脱氢松香酸，二氢松香酸或四氢松香酸的酰胺衍生物的方法，其包括将松香酸，脱氢松香酸，二氢松香酸或四氢松香酸或其活性衍生物与下式的胺反应：HNRR'，其中 R和R'各自为氢，具有3至15个碳原子的直链或支链烷基，低级烯基，环烷基，苯基，苯基烷基和在α处具有低级烷基的苯基烷基 - 位置，条件是其中R和R'都是氢或其中R和R'之一是氢而另一个是苯基的胺被排除在外。本发明还包括所得的酰胺衍生物反应产物，含有有效血清胆固醇降低量的所述酰胺衍生物的组合物及其作为抗动脉硬化剂的用途。

3. 发明授权

US4024280A Abietanilides, their production and use 失效
标题翻译：丁苯替尼，其生产和使用
公开(公告)号：US4024280A
公开(公告)日：1977-05-17
申请号：US576360
申请日：1975-05-12
申请人： Hiromu Murai , Katsuya Ohata , Hiroshi Enomoto , Kenji Sempuku , Koji Kitaguchi , Yukio Fujita , Yoshiaki Yoshikuni , Kohei Kura , Katsuhide Saito , Tamiki Mori , Yasuo Yasutomi
发明人： Hiromu Murai , Katsuya Ohata , Hiroshi Enomoto , Kenji Sempuku , Koji Kitaguchi , Yukio Fujita , Yoshiaki Yoshikuni , Kohei Kura , Katsuhide Saito , Tamiki Mori , Yasuo Yasutomi
IPC分类号： A61K31/16 , A61K31/165 , A61P3/06 , C07C67/00 , C07C231/00 , C07C231/02 , C07C233/00 , C07C233/58 , C07C233/59 , C07C233/60 , C07C102/00 , C07C103/37
CPC分类号： A61K31/165 , C07C233/00 , C07C2103/26
摘要： Process for the preparation of abietanilides which comprises reacting abietic acid, dihydroabietic acid, tetrahydroabietic acid or a reactive derivative thereof with aniline and the products thereby produced, compositions containing the same for reducing blood serum cholesterol and method of use of such compositions.
摘要翻译：制备抗坏血酸二酰苯酯的方法，其包括将松香酸，二氢松香酸，四氢松香酸或其活性衍生物与苯胺和由此产生的产物反应，含有其的含有降低血清胆固醇的组合物和使用该组合物的方法。

4. 发明授权

US4117159A Pharmaceutically active deltab-dihydropimaramide derivatives 失效
标题翻译：药物活性的DELTAB-二氢嘧啶衍生物
公开(公告)号：US4117159A
公开(公告)日：1978-09-26
申请号：US768052
申请日：1977-02-14
申请人： Hiromu Murai , Yukio Fujita , Tamiki Mori , Hiroshi Enomoto , Yoshiaki Yoshikuni
发明人： Hiromu Murai , Yukio Fujita , Tamiki Mori , Hiroshi Enomoto , Yoshiaki Yoshikuni
IPC分类号： C07C233/59 , A61K31/16 , A61K31/165 , A61K31/195 , A61K31/24 , A61P3/06 , A61P29/00 , C07C67/00 , C07C231/00 , C07C233/60 , C07C233/63 , C07C103/37
CPC分类号： C07C2102/10 , C07C2103/26
摘要： N-Phenyl and N-benzyl .DELTA..sup.8 -dihydropimaramides are antiphlogistic and serum cholesterol lowering agents. The compounds, of which N-(2-ethylphenyl)-.DELTA..sup.8 -dihydropimaramide is a representative embodiment, are prepared from reactive derivatives of .DELTA..sup.8 -dihydropimaric acid and the appropriate amine.

5. 发明授权

US4755523A Abietamide derivatives 失效
标题翻译：悬浮酰胺衍生物
公开(公告)号：US4755523A
公开(公告)日：1988-07-05
申请号：US15287
申请日：1987-02-17
申请人： Yoshiaki Yoshikuni , Shoichi Chokai , Yukio Fujita , Takayuki Ozaki
发明人： Yoshiaki Yoshikuni , Shoichi Chokai , Yukio Fujita , Takayuki Ozaki
IPC分类号： C07D231/40 , C07D275/02 , C07D277/44 , C07D277/46 , A61K31/415 , A61K31/425
CPC分类号： C07D231/40 , C07D275/02 , C07D277/46
摘要： Abietamide derivatives of the formula I ##STR1## wherein X is NZ wherein Z is hydrogen, alkyl, unsubstituted or substituted phenyl or X is a sulphur atom; when X is NZ, V is nitrogen, W is , and R is hydrogen or alkyl and when X is a sulphur atom, V is , W is nitrogen, and R is hydrogen, alkyl, phenyl or --CH.sub.2 COOR'; wherein R' is hydrogen or alkyl and is a single or double bond, are useful for treating hyperlipemia and particularly for the prevention and therapy of arteriosclerosis.
摘要翻译：式I的酰胺衍生物其中X为NZ，其中Z为氢，烷基，未取代或取代的苯基或X为硫原子; 当X为NZ时，V为氮，W为，R为氢或烷基，当X为硫原子时，V为，W为氮，R为氢，烷基，苯基或-CH2COOR'; 其中R'是氢或烷基并且是单键或双键，可用于治疗高脂血症，特别是用于预防和治疗动脉硬化。

6. 发明授权

US4855415A Glucosylmoranoline derivatives 失效
标题翻译：葡糖基吗啉衍生物
公开(公告)号：US4855415A
公开(公告)日：1989-08-08
申请号：US91822
申请日：1987-09-01
申请人： Makoto Sugiyama , Yoji Ezure , Yoshiaki Yoshikuni , Yukio Fujita
发明人： Makoto Sugiyama , Yoji Ezure , Yoshiaki Yoshikuni , Yukio Fujita
IPC分类号： A61K31/70 , A61K31/7042 , A61K31/7052 , A61P3/08 , C07H17/02
CPC分类号： C07H17/02 , Y10S514/866
摘要： A compound of formula (I) ##STR1## wherein: B is a divalent substituted or unsubstituted, cyclic or acyclic, saturated or unsaturated hydrocarbon group;A is a linking group selected from the group consisting of --O--, --S--, --N(H)--, --N(R)--, --C(O)-- and combinations of two or more thereof or A is a direct bond; andR is a monovalent substituted or unsubstituted, cyclic or acyclic, saturated or unsaturated hydrocarbon group, a monovalent substituted or unsubstituted aromatic hydrocarbon group, or a monovalent substituted or unsubstituted heterocyclyl provided that B--A--R may not represent hydrogen, lower alkyl, or a monovalent cyclic or acyclic hydrocarbon group having one or more hydroxyl groups, which is useful for inhibiting an increase in blood glucose in humans and for the treatment of diabetes mellitus.

7. 发明授权

US4711898A 4-quinolone derivatives having anti-inflammatory, anti-allergic, antitussive, expectorant and antithrombotic activity 失效
标题翻译：具有抗炎，抗过敏，止咳，祛痰和抗血栓活性的4-喹诺酮衍生物
公开(公告)号：US4711898A
公开(公告)日：1987-12-08
申请号：US781142
申请日：1985-09-27
申请人： Hiroshi Enomoto , Tadatoshi Nomura , Yoshiaki Aoyagi , Shoichi Chokai , Yukio Fujita , Tatsuhiko Kono , Masao Murase , Kichiro Inoue , Masahiro Adachi
发明人： Hiroshi Enomoto , Tadatoshi Nomura , Yoshiaki Aoyagi , Shoichi Chokai , Yukio Fujita , Tatsuhiko Kono , Masao Murase , Kichiro Inoue , Masahiro Adachi
IPC分类号： A61K31/47 , A61P7/02 , A61P11/00 , A61P11/10 , A61P11/14 , A61P37/08 , C07D215/48 , C07D401/04 , C07D405/04 , C07D409/04
CPC分类号： C07D215/48
摘要： 4-Quinolone derivatives of the present invention are useful for their anti-inflammatory, anti-allergenic, antitussive, expectorant and antithrombotic activity. Pharmaceutical compositions containing said compounds and pharmaceutically acceptable salts thereof and methods of treating humans and animals are described herein.
摘要翻译：本发明的4-喹诺酮衍生物可用于其抗炎，抗过敏，止咳，祛痰和抗血栓活性。本文描述了含有所述化合物及其药学上可接受的盐的药物组合物和治疗人和动物的方法。

8. 发明授权

US06567468B1 Motion detection circuit and a noise suppressing circuit including the same 失效
标题翻译：运动检测电路和包括该运动检测电路的噪声抑制电路
公开(公告)号：US06567468B1
公开(公告)日：2003-05-20
申请号：US09394684
申请日：1999-09-13
申请人： Noriyoshi Kato , Yukio Fujita , Misa Kasahara
发明人： Noriyoshi Kato , Yukio Fujita , Misa Kasahara
IPC分类号： H04N712
CPC分类号： G06T7/254
摘要： In a motion detection circuit, a difference signal between the video and one-frame delayed video signals is generated. An Edge signal is generated from the video and delayed video signals. Motion in a target pixel is judged from the interframe difference signal according to the edge signal. A motion judging circuit further includes an LPF and a selector for supplying an output of the LPF or the difference signal. The motion judging circuit may further includes: a peripheral pixel comparing circuit (may be bypassed) for detecting motion at the pixel by checking polarities of the difference signal at an area around the target pixel; a majority detection circuit (may be bypassed) for detecting a majority of the results of the polarity deviation detection circuit to judge the motion with deviation to a side of stopping; and a polarity deviation detecting circuit for judging the motion as moving in the presence of agreement of the polarities of all pixels at any of peripheral areas around the target pixel. The size of the peripheral areas are controlled. The polarity deviation circuit may compensate the result of the majority detection circuit. Width of the edge signal is controlled. A noise suppression apparatus including a motion detection circuit mentioned above is also disclosed.
摘要翻译：在运动检测电路中，产生视频和一帧延迟的视频信号之间的差分信号。从视频和延迟的视频信号产生边沿信号。根据边缘信号从帧间差分信号判断目标像素中的运动。运动判定电路还包括LPF和用于提供LPF的输出或差分信号的选择器。运动判断电路还可以包括：周边像素比较电路（可以旁路），用于通过检查目标像素周围的区域的差异信号的极性来检测像素上的运动; 多数检测电路（可以被旁路），用于检测极性偏差检测电路的大部分结果，以判断具有偏离停止侧的运动; 以及极性偏差检测电路，用于在存在目标像素周围的任何周边区域的所有像素的极性一致的情况下，将运动判断为移动。外围区域的大小被控制。极性偏差电路可以补偿多数检测电路的结果。边缘信号的宽度被控制。还公开了包括上述运动检测电路的噪声抑制装置。

9. 发明授权

US4349644A Melt-blended resin composition of hydrolyzed ethylene/vinyl acetate copolymers 失效
标题翻译：水解乙烯/乙酸乙烯酯共聚物的熔融共混树脂组合物
公开(公告)号：US4349644A
公开(公告)日：1982-09-14
申请号：US250411
申请日：1981-04-02
申请人： Teruo Iwanami , Hiroshi Takida , Yukio Fujita
发明人： Teruo Iwanami , Hiroshi Takida , Yukio Fujita
IPC分类号： C08L23/00 , C08L23/08 , C08L29/04 , C08L101/00 , C08L23/26 , C08L29/02
CPC分类号： C08L23/08 , C08L29/04 , C08L2205/02 , Y10T428/31855 , Y10T428/31909
摘要： A melt-blended composition containing at least two kinds of hydrolyzed ethylene-vinyl acetate copolymers having a different ethylene content from each other within the range of 20 to 55% by mole, a degree of hydrolysis in vinyl acetate component of at least 80% by mole and a specific melt tension as defined herein, the hydrolyzed copolymers included in the largest amount and the second largest amount among the hydrolyzed copolymers constituting the composition having a specific relationship with each other in weight ratio and ethylene content and the fusion curve of the composition indicating substantially single peak. The composition has an improved melt-moldability, and provides molded articles having remarkably reduced fish eyes and uniform thickness or excellent dimensional stability.
摘要翻译：一种熔融共混组合物，其含有至少两种乙烯 - 乙酸乙烯酯共聚物，其乙烯含量彼此不同，为20〜55摩尔％，乙酸乙烯酯组分的水解度为80％以上，摩尔和如本文所定义的特定熔体张力，包含在构成组合物的水解共聚物中最大量和第二大量的水解共聚物的重量比和乙烯含量彼此具有特定关系，组合物的熔融曲线表明基本上单峰。该组合物具有改进的熔体成型性，并且提供具有显着减少的鱼眼和均匀厚度或优异的尺寸稳定性的模制品。

10. 发明申请

US20070042234A1 Liquid fuel type fuel cell and fuel therefor 审中-公开
标题翻译：液体燃料型燃料电池及其燃料
公开(公告)号：US20070042234A1
公开(公告)日：2007-02-22
申请号：US10556253
申请日：2004-03-29
申请人： Ryoichi Okuyama , Masashi Motoi , Yukio Fujita , Eiichi Nomura
发明人： Ryoichi Okuyama , Masashi Motoi , Yukio Fujita , Eiichi Nomura
IPC分类号： H01M8/00 , H01M8/10 , C10L1/32 , C10L1/10
CPC分类号： H01M8/04186 , H01M8/0662 , H01M8/1009 , Y02E60/523
摘要： A dye is added into a methanol/water fuel of a direct methanol fuel cell, and the dye is adsorbed and removed by a filter cartridge provided in the upstream of a cell stack. Carbon black, etc. may be added instead of the dye. Alternatively, a scenting agent such as formic acid and methyl formate, or an antiseptic may be added.
摘要翻译：将染料加入到直接甲醇燃料电池的甲醇/水燃料中，并且通过设置在电池堆的上游的滤芯吸附和除去染料。可以加入炭黑等代替染料。或者，可以加入香味剂如甲酸和甲酸甲酯，或防腐剂。

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