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    • 3. 发明申请
    • Window edge molding for motor vehicle
    • 汽车窗边成型
    • US20060125275A1
    • 2006-06-15
    • US10522384
    • 2003-07-25
    • Yasuhiro WatoHirofumi YamaneKoichi Sakamoto
    • Yasuhiro WatoHirofumi YamaneKoichi Sakamoto
    • B60J10/02
    • B60J10/27B60J10/16B60J10/17B60J10/70
    • A vehicular window molding attached along a gap between a window opening edge of a vehicle body panel and an outer peripheral edge portion of a window pane arranged at the window opening. The vehicular window molding includes a molding main body portion attached to the outer peripheral edge portion of the window pane, a sealing lip portion projected from the molding main body portion to the vehicle body panel for shielding the gap from an exterior direction in a state in which the window molding is attached to the gap of the vehicle body panel and a folded-back lip portion folded back at a free end portion of the sealing lip portion to be brought into elastic contact with an outer face of the vehicle body panel. At least one of back faces of the sealing lip portion and the folded-back lip portion, sticking prevention means for preventing the back faces from sticking to each other is formed at a portion of overlapping the sealing lip portion and the folded-back lip portion.
    • 车窗模制件沿着车身面板的窗口开口边缘和布置在窗户开口处的窗玻璃的外周缘部分之间的间隙附着。 车窗模制件包括附接到窗玻璃的外周边缘部分的成型主体部分,从模制主体部分向车身板突出的密封唇部分,用于在外部方向上屏蔽该间隙 窗口模制件附接到车体面板的间隙上,折回的唇部折回到密封唇部的自由端部,以与车体面板的外表面弹性接触。 在密封唇部和折回唇部的重叠部分形成有密封唇部和折回唇部的至少一个背面,防止背面相互粘合的防粘附装置 。
    • 5. 发明申请
    • Solid formulation with improved solubility and stability, and method for producing said formulation
    • 具有改进的溶解度和稳定性的固体制剂以及生产所述制剂的方法
    • US20060153913A1
    • 2006-07-13
    • US11256201
    • 2005-10-24
    • Shogo YamaneHirofumi YamaneMasaki Sunami
    • Shogo YamaneHirofumi YamaneMasaki Sunami
    • A61K31/47A61K31/454A61K9/20
    • A61K9/2027A61K9/0056A61K9/143A61K9/146A61K9/1635A61K9/1652A61K9/2009A61K9/2054A61K31/225A61K31/454A61K31/47
    • The present invention relates to a solid formulation with improved solubility and maintained stability including a chemical substance poorly soluble in water as a pharmaceutically active ingredient formulated in an improved manner. More specifically, the present invention relates to a solid formulation having improved water-solubility which comprises a chemical substance poorly soluble in water as a pharmaceutically active ingredient, a water-soluble polymer substance and an inorganic porous substance, characterized in that (1) the chemical substance poorly soluble in water forms a solid dispersion together with the water-soluble polymer substance, (2) the water-soluble polymer substance forming the solid dispersion is in the form of fine pieces, and (3) the water-soluble polymer substance is in the form of fine pieces is maintained to be adsorbed on and/or adhered to the surface of the inorganic porous substance. The solid formulation can be produced by stirring and mixing a solution obtained by dissolving a chemical substance poorly soluble in water as a pharmaceutically active ingredient and a water-soluble polymer substance in an organic solvent with an inorganic porous substance and then granulating and drying the mixture.
    • 本发明涉及具有改善的溶解性和保持稳定性的固体制剂,包括以改进的方式配制的药物活性成分不溶于水的化学物质。 更具体地说,本发明涉及具有改善的水溶性的固体制剂,其包含难溶于水作为药物活性成分的化学物质,水溶性聚合物物质和无机多孔物质,其特征在于(1) 难溶于水的化学物质与水溶性聚合物物质一起形成固体分散体,(2)形成固体分散体的水溶性聚合物物质为细片,(3)水溶性聚合物物质 以细片的形式被保持吸附在无机多孔物质表面上和/或附着于无机多孔物质的表面上。 固体制剂可以通过将通过将难溶于水的化学物质作为药物活性成分和水溶性聚合物物质溶解在有机溶剂中而获得的溶液与无机多孔物质混合,然后将混合物制粒和干燥来制备 。
    • 6. 发明授权
    • Window edge molding for motor vehicle
    • 汽车窗边成型
    • US07354093B2
    • 2008-04-08
    • US10522384
    • 2003-07-25
    • Yasuhiro WatoHirofumi YamaneKoichi Sakamoto
    • Yasuhiro WatoHirofumi YamaneKoichi Sakamoto
    • B60J10/02
    • B60J10/27B60J10/16B60J10/17B60J10/70
    • A vehicular window molding attached along a gap between a window opening edge of a vehicle body panel and an outer peripheral edge portion of a window pane arranged at the window opening. The vehicular window molding includes a molding main body portion attached to the outer peripheral edge portion of the window pane, a sealing lip portion projected from the molding main body portion to the vehicle body panel for shielding the gap from an exterior direction in a state in which the window molding is attached to the gap of the vehicle body panel and a folded-back lip portion folded back at a free end portion of the sealing lip portion to be brought into elastic contact with an outer face of the vehicle body panel. At least one of back faces of the sealing lip portion and the folded-back lip portion, sticking prevention means for preventing the back faces from sticking to each other is formed at a portion of overlapping the sealing lip portion and the folded-back lip portion.
    • 车窗模制件沿着车身面板的窗口开口边缘和布置在窗户开口处的窗玻璃的外周缘部分之间的间隙附着。 车窗模制件包括附接到窗玻璃的外周边缘部分的成型主体部分,从模制主体部分向车身板突出的密封唇部分,用于在外部方向上屏蔽该间隙 窗口模制件附接到车体面板的间隙上,折回的唇部折回到密封唇部的自由端部,以与车体面板的外表面弹性接触。 在密封唇部和折回唇部的重叠部分形成有密封唇部和折回唇部的至少一个背面,防止背面相互粘合的防粘附装置 。
    • 7. 发明授权
    • Weather strip for use on a sunroof
    • 天气条使用在天窗上
    • US06832451B2
    • 2004-12-21
    • US10358712
    • 2003-02-05
    • Takashi YamashitaMasayuki DaioMasaharu OhnishiHirofumi YamaneTatsuaki UeharaKoichi Hotta
    • Takashi YamashitaMasayuki DaioMasaharu OhnishiHirofumi YamaneTatsuaki UeharaKoichi Hotta
    • E06B722
    • B60J10/24B60J10/30B60J10/82
    • There is provided a weather strip for use on a sunroof which can be firmly built in a seal holder even if there occur variations in molding dimensions. The weather strip comprises a thicker base part which is engaged in a built-in recess of the seal holder fixed to a roof glass, a hollow seal part which elastically contacts a roof panel, and a thinner barrel part which is integrally formed between the thicker base part and the hollow seal part and is clamped by an upper protrusion part and a lower protrusion part which are formed in the built-in recess to protrude therein, wherein a continuous angle between an upper surface of the thinner barrel part and the hollow seal part and that between a lower surface of the thinner barrel part and the hollow seal part are set 90° respectively, and an ascent slope is formed on the upper surface of the thinner barrel part and ascends aslant from the hollow seal part toward the thicker base part, and a descent slope is formed on the lower surface of the thinner barrel part and descends aslant from the hollow seal part toward the thicker base part.
    • 提供了一种用于天窗的天气条,即使发生了成型尺寸的变化,其也可以牢固地内置在密封保持器中。 防风条包括较厚的基部,其接合在固定到屋顶玻璃上的密封保持器的内置凹部中,与顶板弹性接触的中空密封部以及较厚的筒部,该较薄的筒部一体地形成在较厚的 基部和中空密封部分,并且被形成在内置凹部中的突出部分和下突出部分夹紧,其中,较薄筒部的上表面和中空密封件之间的连续角度 部分,并且较薄的筒部的下表面和中空密封部之间分别设定为90°,并且在较薄的筒部的上表面上形成上升斜面,并且从中空密封部朝向较厚的基部上升 部分,并且在较薄筒部的下表面上形成下坡,并从中空密封部朝向较厚的基部倾斜下降。
    • 8. 发明授权
    • Weather strip for use on a sunroof
    • 天气条使用在天窗上
    • US06811213B2
    • 2004-11-02
    • US10358683
    • 2003-02-05
    • Takashi YamashitaMasayuki DaioMasaharu OhnishiHirofumi YamaneTatsuaki UeharaKoichi Hotta
    • Takashi YamashitaMasayuki DaioMasaharu OhnishiHirofumi YamaneTatsuaki UeharaKoichi Hotta
    • B60J1012
    • B60J10/246B60J10/50B60J10/82
    • There is provided a weather strip for use on a sunroof capable of preventing squeak noises being generated in advance between a hollow seal part and a roof panel during traveling of a car by allowing the hollow seal part to satisfactorily follow vibrations of the roof panel. The weather strip ensures sealing property between a roof glass mounted on the sunroof of a car and a roof panel and comprises a built-in base part attached to the roof glass, and a hollow seal part composed of continuous ends integrally formed with the built-in base part and having substantially a circular cross section, a tip end contact part elastically contacting the roof panel, wherein thicker parts protruding inward and being continuous with the built-in base part are formed on the continuous ends of the hollow seal part and protrusions protruding inward are formed on substantially middle parts between the continuous ends and the tip end contact part.
    • 提供了一种在天窗上使用的防风条,其能够通过允许中空密封部分令人满意地跟随屋顶板的振动来防止在行驶过程中预先在中空密封部分和屋顶板之间产生吱吱声。 耐候条件确保安装在汽车天窗上的屋顶玻璃与屋顶板之间的密封性,并且包括附接到屋顶玻璃的内置基座部分和由内置的基座部分组成的中空密封部分, 在基部上具有大致圆形横截面,顶端接触部分与顶板弹性接触,其中向内突出并与内置基部连续的较厚部分形成在中空密封部分的连续端部和突起部 向内突出形成在连续端部和前端接触部分之间的大致中间部分上。