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1. 发明专利

JP2004161684A Bioactive substance-containing film preparation for curing wound 审中-公开
标题翻译：用于固化的生物物质包装膜的制备
公开(公告)号：JP2004161684A
公开(公告)日：2004-06-10
申请号：JP2002330078
申请日：2002-11-13
申请人： Higeta Shoyu Co Ltd , Nitto Denko Corp , Noveltec:Kk , Protein Express:Kk , ヒゲタ醤油株式会社 , 日東電工株式会社 , 有限会社ノベルテック , 株式会社プロテイン・エクスプレス
发明人： OKADA KATSUHIRO , MURAKAMI YOSHIHIDE , HAMADA MASASHI , MATSUDA HIROYOSHI
IPC分类号： A61K9/70 , A61K38/00 , A61K45/00 , A61K47/10 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/42 , A61P17/02
摘要： PROBLEM TO BE SOLVED: To provide a preparation for curing wound, containing a bioactive substance having activities for promoting the cure of the wound in a substrate of a water-soluble polymer, and topically releasing the bioactive substance in an effective amount for promoting the cure of the wound by being pasted or applied on the wound.
SOLUTION: The film preparation for curing the wound is obtained by formulating the bioactive substance having the activities for promoting the curing of the wound with the substrate of the water-soluble polymer. The film preparation for curing the wound provides little physicochemical irritation because of flexibility against the skin, can adhere to an uneven lip of the wound because of traceability, and enables a minute amount of the active substance to be administered accurately and effectively.
COPYRIGHT: (C)2004,JPO
摘要翻译：要解决的问题：提供一种用于治疗伤口的制剂，其含有具有促进伤口在水溶性聚合物的基质中固化的活性的生物活性物质，并且有效量地将生物活性物质局部释放通过粘贴或施加在伤口上来促进伤口的治愈。解决方案：用于固化伤口的膜制剂通过配制具有促进伤口固化的活性的生物活性物质与水溶性聚合物的底物而获得。用于固化伤口的膜制剂由于对皮肤的柔韧性而提供很少的物理化学刺激性，因为可追溯性而可以附着在伤口的不均匀的唇缘上，并且能够精确有效地施用微量的活性物质。版权所有（C）2004，JPO

2. 发明专利

JP2008188414A Poultice package structure 有权
标题翻译： POULATCE包装结构
公开(公告)号：JP2008188414A
公开(公告)日：2008-08-21
申请号：JP2007334141
申请日：2007-12-26
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： OKADA KATSUHIRO , IWAO YOSHIHIRO , MATSUOKA KENSUKE
IPC分类号： A61F13/02
CPC分类号： A61F13/0203 , A61F13/551 , A61F15/001
摘要： PROBLEM TO BE SOLVED: To provide a poultice package structure which allows a poultice easily to be taking out of a package. SOLUTION: The poultice package structure houses a poultice in a package which is formed by sealing the periphery of a flat first sheet and the periphery of a molded second sheet, wherein the poultice includes a support, an adhesive layer piled on at least one side of the support, and a release liner for protecting the adhesive surface of the adhesive layer; and the second sheet has a convex which has a larger flat outer shape than that of the release liner at least approximately in the center, and the concave is shaped to have at least one concave. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种允许轻易将包装袋从包装中取出的泥敷包装结构。解决方案：泥敷包装结构在通过密封平坦的第一片材的周边和模制的第二片材的周边形成的包装中容纳泥泞剂，其中，所述泥敷剂包括支撑体，至少堆积的粘合剂层支撑体的一侧，以及用于保护粘合剂层的粘合剂表面的剥离衬垫; 并且所述第二片具有至少大致在中心具有比所述剥离衬垫更大的平坦外形的凸部，并且所述凹部成形为具有至少一个凹部。版权所有（C）2008，JPO＆INPIT

3. 发明专利

JP2008127351A Skin adhesive patch preparation 有权
标题翻译：皮肤粘合剂配方
公开(公告)号：JP2008127351A
公开(公告)日：2008-06-05
申请号：JP2006315751
申请日：2006-11-22
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： IWAO YOSHIHIRO , OKUBO KATSUYUKI , OKADA KATSUHIRO , MATSUOKA KENSUKE
IPC分类号： A61K9/70
CPC分类号： A61K9/7053 , A61K9/7061 , A61K9/7069 , A61L15/26 , A61L15/58 , B32B7/12 , B32B27/12 , C09J7/29 , C09J2400/263 , C09J2467/006 , Y10T156/10 , Y10T428/24959 , C08L67/00
摘要： PROBLEM TO BE SOLVED: To provide a highly stable skin adhesive patch preparation with little irritation to skin, flexible and highly follow-up to skin. SOLUTION: The skin adhesive patch preparation is provided with a support body and an adhesive layer containing an effective ingredient at least on one side of the support body made of a polyester film with 0.5-6.0 μm thickness directly bound with a polyester non-woven fabric. The adhesive layer is preferably directly or indirectly laminated on the non-woven fabric of the support body. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供高度稳定的皮肤贴剂制剂，对皮肤刺激性很小，柔软且高度跟踪皮肤。皮肤贴剂制剂具有支撑体和粘合剂层，所述粘合剂层至少在由聚酯薄膜制成的支撑体的至少一侧上，所述聚酯薄膜的直径为0.5-6.0μm，直接与聚酯非结合编织物。粘合剂层优选直接或间接地层压在支撑体的无纺织物上。版权所有（C）2008，JPO＆INPIT

4. 发明专利

JP2007186500A Adhesive preparation 有权
标题翻译：胶粘制品
公开(公告)号：JP2007186500A
公开(公告)日：2007-07-26
申请号：JP2006328952
申请日：2006-12-06
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： IWAO YOSHIHIRO , OKUBO KATSUYUKI , OKADA KATSUHIRO
IPC分类号： A61K9/70 , A61K47/10 , A61K47/32
CPC分类号： A61K9/7053 , A61K47/10 , A61K47/32
摘要： PROBLEM TO BE SOLVED: To provide an adhesive preparation for percutaneously administering a medicine liquid at room temperature or at temperatures near to the room temperature, which uses a polyisobutylene-based adhesive as an adhesive, inhibits the bleeding of the medicine, and has sufficient adhesive characteristics.
SOLUTION: This adhesive preparation 10 is characterized by laminating an adhesive layer 2 to one side of a support 1. This adhesive layer 2 comprises a 12 to 28C branched monohydric alcohol, the medicine (excluding the free base of bisoprolol) liquid at room temperature or near to the room temperature, and a polyisobutylene-based adhesive. Thereby, the compatibility of the polyisobutylene-based adhesive with the medicine can specifically be enhanced. Consequently, the amount of the medicine can be increased, and the bleeding of the free base of the bisoprolol from the adhesive layer can be prevented. Sufficiently adhesive characteristics on practical aspects can be obtained.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：待解决的问题：提供一种用于在室温或接近室温的温度下经皮施用药液的粘合剂制剂，其使用聚异丁烯基粘合剂作为粘合剂，抑制药物的渗色，并且具有足够的粘合特性。解决方案：该粘合剂10的特征在于将粘合剂层2层压到载体1的一侧。该粘合剂层2包含12至28℃的支化一元醇，药物（不包括比索洛尔的游离碱）液体室温或接近室温，以及聚异丁烯类粘合剂。由此，能够提高聚异丁烯类粘合剂与药物的相容性。因此，可以增加药物的量，并且可以防止比索洛尔的游离碱从粘合剂层渗出。可以获得实用方面的足够的粘合特性。版权所有（C）2007，JPO＆INPIT

5. 发明专利

JP2005152602A Medical pressure-sensitive adhesive sheets and method for producing the same 有权
标题翻译：医用压敏粘合片及其制造方法
公开(公告)号：JP2005152602A
公开(公告)日：2005-06-16
申请号：JP2004273219
申请日：2004-09-21
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： YAMAMOTO HIROKO , KOMORI KENJI , OKADA KATSUHIRO
IPC分类号： A61F13/02 , A61L15/58
摘要： PROBLEM TO BE SOLVED: To provide medical pressure-sensitive adhesive sheets which have appropriate tack strength and acceptable processability, so that physical stimulation given to an adherend when they are peeled from the adherend can be maintained to low levels and of which the support layer is prevented from undergoing swelling deformation, and to provide a method for producing the same.
SOLUTION: The medical pressure-sensitive adhesive sheets includes a pressure-sensitive adhesive layer on at least one side of the support layer, wherein the pressure-sensitive adhesive layer is formed with an adhesive composed mainly of an acrylic polymer in 100 wt.% and a compatible component that is compatible with the acrylic polymer, and is in liquid-state or paste-state at room temperature, in 30-100 wt.%. The support layer contains a compatible component that is compatible with the acrylic polymer and is in liquid-state or paste-state at room temperature, the amount of the compatible component contained in the support layer is 70% or less of the amount of the compatible component contained in the pressure-sensitive adhesive layer and the support layer has an elongation of 200% or more in a state where the support layer contains no compatible component.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供具有适当的粘着强度和可接受的加工性的医用压敏粘合片，使得当被粘物从被粘物剥离时对被粘物的物理刺激能够保持在低水平，其中防止支撑层发生溶胀变形，并提供其制造方法。解决方案：医用压敏粘合片包括在支撑层的至少一侧上的压敏粘合剂层，其中压敏粘合剂层由主要由丙烯酸类聚合物组成的粘合剂形成100重量份％和与丙烯酸类聚合物相容并且在室温下处于液态或糊状态的相容成分为30-100重量％。支撑层含有与丙烯酸类聚合物相容并且在室温下处于液态或糊状态的相容成分，载体层中所含相容成分的量为相容性的70％以下包含在压敏粘合剂层和支撑层中的组分在支撑层不含相容成分的状态下具有200％以上的伸长率。版权所有（C）2005，JPO＆NCIPI

6. 发明专利

JP2005066160A Adhesive sheet and its manufacture method 有权
标题翻译：胶粘剂及其制造方法
公开(公告)号：JP2005066160A
公开(公告)日：2005-03-17
申请号：JP2003302615
申请日：2003-08-27
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： OKADA KATSUHIRO , SASAKI YASUYUKI , SUZUKI KIYOSHI , KUNIYA MASAYOSHI
IPC分类号： A61F13/02 , A61F13/00
摘要： PROBLEM TO BE SOLVED: To provide an adhesive sheet for preventing adhesion onto a package material, for example. SOLUTION: The adhesive sheet includes an elastomer film on one surface of a support film. An adhesive layer is arranged on the elastomer film, and projection/recessions are formed on an outermost layer at the opposite side of the adhesive layer. The projections/recessions has a function of, for example, preventing the outermost layer from adhering onto a contact surface. The heating shrinkage ratio of the support film is not more than 3.0% in a longitudinal direction and less than 1.2% in a transverse direction. Preferably, the adhesive layer is formed of a composition which includes an acrylic polymer as a main component and contains a compatible component being compatible with the acrylic polymer and normally in liquid or paste form. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供例如用于防止粘附到包装材料上的粘合片。解决方案：粘合片在支撑膜的一个表面上包括弹性体膜。粘合层设置在弹性体膜上，并且在粘合剂层的相对侧的最外层上形成突起/凹陷。突起/凹陷具有例如防止最外层粘附到接触表面上的功能。支撑膜的加热收缩率在长度方向上不大于3.0％，在横向方向上小于1.2％。优选地，粘合剂层由包含丙烯酸类聚合物作为主要成分并且包含与丙烯酸类聚合物相容并且通常为液体或糊状形式的相容成分的组合物形成。版权所有（C）2005，JPO＆NCIPI

7. 发明专利

JP2007037900A Adhesive sheet and production method of adhesive sheet 有权
标题翻译：粘合片的粘合片和生产方法
公开(公告)号：JP2007037900A
公开(公告)日：2007-02-15
申请号：JP2005227875
申请日：2005-08-05
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： OKADA KATSUHIRO , SASAKI YASUYUKI , SUZUKI KIYOSHI , YOSHIKAWA TOSHIYUKI
IPC分类号： A61F13/02
摘要： PROBLEM TO BE SOLVED: To provide an adhesive sheet having an excellent producibility and processability and peelability that an elastomer film does not easily peeled from a support film at the time of production and the support film can be peeled and removed from the elastomer film when the adhesive sheet is used. SOLUTION: In the adhesive sheet, which has a polyurethane film on one side surface of the support film and an adhesive agent layer is provided on the polyurethane film, the support film consists of a resin containing polypropylene, polyethylene and an ethylene-vinyl acetate copolymer as main component. It is desirable that this adhesive agent layer is composed of a composition containing a compatible component having an acrylic polymer as a main component, compatible to the acrylic polymer, and having a liquid or paste state at normal temperature. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种生产性和加工性和剥离性优异的粘合片，使得弹性体膜在制造时不容易从支撑膜剥离，并且支撑膜可以从弹性体剥离和除去当使用粘合片时胶片。解决方案：在聚氨酯膜上设置在支撑膜的一个侧面上具有聚氨酯膜和粘合剂层的粘合片中，支撑膜由含有聚丙烯，聚乙烯和乙烯 - 乙酸乙烯酯共聚物为主要成分。理想的是，这种粘合剂层由含有丙烯酸类聚合物作为主要成分的相容成分的组合物构成，与丙烯酸类聚合物相容，并且在常温下具有液体或糊状。版权所有（C）2007，JPO＆INPIT

8. 发明专利

JP2005337869A Method for evaluating skin irritation of pasting material 有权
标题翻译：评估材料刺激皮肤刺激的方法
公开(公告)号：JP2005337869A
公开(公告)日：2005-12-08
申请号：JP2004156751
申请日：2004-05-26
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： HAMADA MASASHI , YAMAMOTO HIROKO , OKADA KATSUHIRO , MARUO HIROKI , HOSAKA KYOKO
IPC分类号： G01N33/50 , A61L15/58 , G01N33/48
摘要： PROBLEM TO BE SOLVED: To provide a method for evaluating the relatively weak irritation properties to the skin caused during the sticking of a pasting material and incapable of being discriminated by a conventional evaluation method.
SOLUTION: This method for evaluating the irritation properties to the skin caused during the sticking of the pasting material includes a process for sampling the skin of a part to which the pasting material is stuck in the state that the pasting material is stuck and a process for measuring the thickness of the epidermis of the sampled skin.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种用于评估在粘贴材料粘附期间引起的对皮肤的相对较弱的刺激性能并且不能被常规评估方法区分的方法。解决方案：用于评价在粘贴材料粘附期间引起的对皮肤的刺激性质的方法包括在粘贴材料被卡住的状态下对粘贴材料粘贴的部分的皮肤进行取样的方法，以及用于测量取样皮肤的表皮的厚度的方法。版权所有（C）2006，JPO＆NCIPI

9. 发明专利

JP2005218496A Film base material for adhesive skin patch and adhesive skin patch 审中-公开
标题翻译：胶粘剂胶粘剂胶粘剂和粘合皮肤贴
公开(公告)号：JP2005218496A
公开(公告)日：2005-08-18
申请号：JP2004026773
申请日：2004-02-03
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： OKADA KATSUHIRO , SUZUKI KIYOSHI , SASAKI YASUYUKI , YOSHIKAWA TOSHIYUKI
IPC分类号： A61K9/70 , A61F5/01 , A61F13/02 , C08J5/18
摘要： PROBLEM TO BE SOLVED: To provide a film base material for an adhesive skin patch having moisture permeability and a following performance to the skin and to provide the adhesive skin patch using the same.
SOLUTION: This film base material for the adhesive skin patch is composed of ether-based urethane resin with the thickness of 10 μm-50 μm, at least unidirectional tensile strength of 5-30 N/20 mm width, at least unidirectional elongation of 400-1,000 %, and at least unidirectional tear strength of 400-1,000 N/cm. Preferably, this film base material for the adhesive skin patch has the moisture permeability of 800-4,000 g/m
2 ×24 hrs. This adhesive skin patch can be manufactured by forming a pressure-sensitive adhesive layer on one face of the film base material for the adhesive skin patch.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种用于具有透湿性和以下性能的粘合性皮肤贴剂的胶片基材，并提供使用其的胶粘剂皮肤贴剂。解决方案：用于粘合性皮肤贴剂的该薄膜基材料由厚度为10μm-50μm的醚基聚氨酯树脂组成，至少单向拉伸强度为5-30N / 20mm宽度，至少单向伸长率为400-1,000％，至少单向撕裂强度为400-1,000N / cm。优选地，用于粘合性皮肤贴剂的该薄膜基材具有800-4,000g / m 2 / SP>×24小时的透湿性。该粘合性皮肤贴剂可以通过在粘合性皮肤贴剂的薄膜基材的一个面上形成压敏粘合剂层来制造。版权所有（C）2005，JPO＆NCIPI

10. 发明专利

JP2005120008A Adhesive antimicrobial sheet and antimicrobial method using the same 有权
标题翻译：粘合抗菌片和使用其的抗微生物方法
公开(公告)号：JP2005120008A
公开(公告)日：2005-05-12
申请号：JP2003355892
申请日：2003-10-16
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： HAMADA MASASHI , OKADA KATSUHIRO , KINOSHITA TAKASHI , NAKANISHI TOKUJI , SAWADA YUKIMASA
IPC分类号： A61K9/70 , A61F13/02 , A61K31/122 , A61L15/14 , A61L15/44 , A61L15/46 , A61L15/58 , A61P31/04
CPC分类号： A61L15/46 , A61L15/58 , A61L2300/404
摘要： PROBLEM TO BE SOLVED: To obtain an adhesive antimicrobial sheet that contains a volatile antimicrobial agent in an adhesive layer and exhibits antimicrobial action not only on the surface of an attached part but also on a space in the vicinity of the attached part and to provide an antimicrobial method using the sheet.
SOLUTION: The adhesive antimicrobial sheet comprises the nonaqueous adhesive layer containing the volatile antimicrobial agent formed on one side of a substrate and has at least 1,000 g/m
2 ×24 hrs permeability of the whole sheet. A nonwoven fabric or a porous plastic sheet is preferable as the substrate. In the case of a non-porous plastic sheet, a polyurethane-based resin or a polyamide-based resin is preferably used. Hinokitiol is preferable as the volatile antimicrobial agent. Its inclusion compound is also used. An acrylic adhesive obtained by polymerizing a (meth)acrylic acid alkyl ester as a main component is preferably used as the adhesive.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：为了获得在粘合剂层中含有挥发性抗微生物剂的粘合性抗菌片材，并且不仅在附着部件的表面上，而且在附着部件附近的空间上表现出抗微生物作用，以提供使用该片材的抗微生物方法。解决方案：粘合抗菌片材包含含有形成在基材一侧上的挥发性抗微生物剂的非水性粘合剂层，并且其整个片材具有至少1,000g / m 2 SPF×24小时的渗透性。作为基材，优选无纺布或多孔塑料片。在无孔塑料片的情况下，优选使用聚氨酯类树脂或聚酰胺类树脂。作为挥发性抗微生物剂，优选桧醇。也使用其包合物。优选使用通过聚合（甲基）丙烯酸烷基酯作为主要成分获得的丙烯酸类粘合剂作为粘合剂。版权所有（C）2005，JPO＆NCIPI

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