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1. 发明授权

US5428059A Benzopyran derivatives and an anti-allergic agent possessing the same as the active ingredient 失效
标题翻译：苯并吡喃衍生物和具有与活性成分相同的抗过敏剂
公开(公告)号：US5428059A
公开(公告)日：1995-06-27
申请号：US938132
申请日：1992-11-20
申请人： Hidetsugu Takagaki , Mitsuru Sakai , Hiromu Takahashi , Kazuhiko Inazawa , Masayoshi Abe , Nobuyuki Kimura
发明人： Hidetsugu Takagaki , Mitsuru Sakai , Hiromu Takahashi , Kazuhiko Inazawa , Masayoshi Abe , Nobuyuki Kimura
IPC分类号： C07D311/56 , A61K31/35
CPC分类号： C07D311/56
摘要： The present invention relates to an extremely effective anti-allergic agent with a low toxicity, which possesses as its active ingredient a benzopyran derivative described by the general formula below (in the formula, R.sup.1 and R.sup.2 are each respectively a hydrogen atom, an acyl group, an alkyl group having 1.about.12 carbon atoms, or an alkenyl group having 2.about.10 carbon atoms; and R.sup.3 is a hydroxyl group, an acyloxy group, an alkoxy group having 1.about.10 carbon atoms, or an alkenyloxy group having 2.about.10 carbon atoms).General Formula ##STR1##
摘要翻译： PCT No.PCT / JP92 / 00095 Sec。 371日期：1992年11月20日 102（e）1992年11月20日PCT PCT 1992年1月31日PCT公布。第WO92 / 13852号公报本发明涉及一种毒性低的极有效的抗过敏剂，它具有下列通式所示的苯并吡喃衍生物作为其活性成分（式中，R1和R2各自分别为氢原子，酰基，具有1个碳原子的烷基或具有2个碳原子的烯基; R3是羟基，酰氧基，具有1-10个碳原子的烷氧基，或具有2个碳原子的烯氧基）。通用公式

2. 发明授权

US6114352A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient 有权
标题翻译：喹啉酮衍生物和抗过敏剂与所述喹啉酮衍生物作为活性成分
公开(公告)号：US6114352A
公开(公告)日：2000-09-05
申请号：US223271
申请日：1998-12-30
申请人： Hidetsugu Takagaki , Masayoshi Abe , Mitsuru Sakai , Yasuo Aoki , Shigenori Nakanishi , Nobuyuki Kimura , Akihide Koda
发明人： Hidetsugu Takagaki , Masayoshi Abe , Mitsuru Sakai , Yasuo Aoki , Shigenori Nakanishi , Nobuyuki Kimura , Akihide Koda
IPC分类号： A61K31/00 , A61K31/47 , A61K31/4704 , A61P11/00 , A61P11/06 , A61P37/00 , A61P37/08 , C07D215/22 , C07D215/38
CPC分类号： C07D215/22 , C07D215/38
摘要： The present invention offers 7-aminoquinolinone derivatives, physiologically acceptable salts thereof, anti-allergic agents having as an active ingredient a 7-aminoquinolinone derivative or physiologically acceptable salt thereof, and 7-nitroquinolinone derivatives, wherein the 7-aminoquinolinone derivative is expressed by the following general formula (I): ##STR1## wherein R.sub.1 is a hydrogen atom or an alkyl group;R.sub.2 and R.sub.3 are mutually different groups, each of which is selected from among hydrogen atoms, acyl groups, alkyl groups or alkenyl groups; andR.sub.4 and R.sub.5 are mutually different or identical groups, each of which is selected from among hydrogen atoms, acyl groups, alkyl groups, alkenyl groups or aralkyl groups;and physiologically acceptable salts thereof.
摘要翻译：本发明提供了7-氨基喹啉酮衍生物，其生理上可接受的盐，作为活性成分的7-氨基喹啉酮衍生物或其生理学上可接受的盐的抗过敏剂和7-硝基喹啉酮衍生物，其中7-氨基喹啉酮衍生物由通式（I）：其中R 1是氢原子或烷基; R2和R3是相互不同的基团，其各自选自氢原子，酰基，烷基或烯基; 并且R 4和R 5是相互不同或相同的基团，其各自选自氢原子，酰基，烷基，烯基或芳烷基; 及其生理上可接受的盐。

3. 发明授权

US5580552A 7-glycosyloxybenzopyran derivative and antiallergic agent containing the derivative as active ingredient 失效
标题翻译： 7-糖氧基苯并吡喃衍生物和含有该衍生物作为活性成分的抗过敏剂
公开(公告)号：US5580552A
公开(公告)日：1996-12-03
申请号：US446115
申请日：1995-05-19
申请人： Hidetsugu Takagaki , Masayoshi Abe , Yasuo Aoki , Mitsuru Sakai , Nobuyuki Kimura
发明人： Hidetsugu Takagaki , Masayoshi Abe , Yasuo Aoki , Mitsuru Sakai , Nobuyuki Kimura
IPC分类号： A61K31/70 , A61K31/7042 , A61K31/7048 , A61P37/08 , C07H17/075 , A01N43/04
CPC分类号： C07H17/075 , Y02P20/55
摘要： A 7-glycosyloxybenzopyran derivative represented by the following formula (I) ##STR1## wherein, R is a hydrogen atom, an acyl group, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group, R.sub.2 is a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group or an aralkyl group and R.sub.3 is a glycosyl group whose hydroxyl group is protected or not protected, selected from the group consisting of glucosyl, mannosyl and galactosyl groups, and physiologically acceptable salts thereof.
摘要翻译：由下式（I）表示的7-糖氧基苯并吡喃衍生物其中，R为氢原子，酰基，烷基，环烷基，链烯基或芳烷基，R2为氢原子，烷基，环烷基，烯基或芳烷基，R3是羟基被保护或未被保护的糖基，选自葡糖基，甘露糖基和半乳糖基，以及生理上可接受的盐其中。

4. 发明授权

US5942521A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient 失效
公开(公告)号：US5942521A
公开(公告)日：1999-08-24
申请号：US784915
申请日：1997-01-16
申请人： Hidetsugu Takagaki , Masayoshi Abe , Mitsuru Sakai , Yasuo Aoki , Shigenori Nakanishi , Nobuyuki Kimura , Akihide Koda
发明人： Hidetsugu Takagaki , Masayoshi Abe , Mitsuru Sakai , Yasuo Aoki , Shigenori Nakanishi , Nobuyuki Kimura , Akihide Koda
IPC分类号： A61K31/00 , A61K31/47 , A61K31/4704 , A61P11/00 , A61P11/06 , A61P37/00 , A61P37/08 , C07D215/22 , C07D215/38
CPC分类号： C07D215/22 , C07D215/38
摘要： The present invention offers 7-aminoquinolinone derivatives, physiologically acceptable salts thereof, anti-allergic agents having as an active ingredient a 7-aminoquinolinone derivative or physiologically acceptable salt thereof, and 7-nitroquinolinone derivatives, wherein the 7-aminoquinolinone derivative is expressed by the following general formula (I): ##STR1## wherein R.sub.1 is a hydrogen atom or an alkyl group;R.sub.2 and R.sub.3 are mutually different groups, each of which is selected from among hydrogen atoms, acyl groups, alkyl groups or alkenyl groups; andR.sub.4 and R.sub.5 are mutually different or identical groups, each of which is selected from among hydrogen atoms, acyl groups, alkyl groups, alkenyl groups or aralkyl groups; and physiologically acceptable salts thereof.

5. 发明授权

US5525595A 3- or 4-glycosyloxybenzopyran derivative and antiallergic agent containing the derivative as active ingredient 失效
标题翻译： 3-或4-糖氧基苯并吡喃衍生物和含有该衍生物作为活性成分的抗过敏剂
公开(公告)号：US5525595A
公开(公告)日：1996-06-11
申请号：US312192
申请日：1994-09-26
申请人： Hidetsugu Takagaki , Masayoshi Abe , Yasuo Aoki , Yoshiyuki Sano , Mitsuru Sakai , Nobuyuki Kimura
发明人： Hidetsugu Takagaki , Masayoshi Abe , Yasuo Aoki , Yoshiyuki Sano , Mitsuru Sakai , Nobuyuki Kimura
IPC分类号： C07H17/075 , A61K31/70
CPC分类号： C07H17/075 , Y10S514/826 , Y10S514/829 , Y10S514/885
摘要： There are provided novel compounds of the formulae I and II: ##STR1## and their physiologically acceptable salts. The compounds according to the present invention and their physiologically acceptable salts exhibit an antiallergic activity and are useful for treating allergic diseases.
摘要翻译：提供式I和II的新化合物：其中（I）和（II）化合物及其生理上可接受的盐。根据本发明的化合物及其生理上可接受的盐表现出抗过敏活性，并且可用于治疗过敏性疾病。

6. 发明授权

US6136822A Quinolinone derivative, method for preparing the same, and anti-allergic agent 有权
标题翻译：喹啉酮衍生物，其制备方法和抗过敏剂
公开(公告)号：US6136822A
公开(公告)日：2000-10-24
申请号：US201662
申请日：1998-12-01
申请人： Hidetsugu Takagaki , Shinobu Yamaguchi , Masayoshi Abe , Mitsuru Sakai , Osamu Misumi
发明人： Hidetsugu Takagaki , Shinobu Yamaguchi , Masayoshi Abe , Mitsuru Sakai , Osamu Misumi
IPC分类号： C07D215/22 , A61K31/00 , A61K31/47 , A61K31/4704 , A61P37/00 , A61P37/08 , C07C235/16 , C07D215/38 , C07D215/40 , C07D215/48 , C07D401/12 , C07D405/04 , C07D405/06 , C07D215/16 , C07D215/20 , C07D215/36
CPC分类号： C07D215/22 , C07C235/16 , C07D215/38 , C07D215/40 , C07D215/48 , C07D401/12 , C07D405/04 , C07D405/06
摘要： The present invention relates to a simple method for preparing a quinolinone derivative, which is effective as a medicine, e.g., as an agent for treating allergic diseases and the like; novel amide derivatives effective as an intermediate in the method; novel quinolinone derivatives obtained according to the method; and an anti-allergic agent containing a quinolinone derivative and/or physiological salt of the same as the active ingredients. The quinolinone derivative is expressed by the following general formula (II); and the method is characterized in that an amide derivative, expressed by the following formula (I), is reacted with a basic agent, followed by intramolecular ring formation: ##STR1## wherein R.sub.1 represents a hydrogen atom, an alkyl group, an alkyl group containing a hydroxyl group an alkenyl group, or an aryl group; R.sub.2 represents an alkyl group, an alkenyl group, an aryl group, or an aralkyl group; R.sub.3 represents a reactive carboxyl group; and R.sub.4 to R.sub.7 represent, respectively and independently, a hydrogen atom; a hydroxyl group; an alkyl group; an alkoxy group; an alkenyl group; an alkenyloxy group; an aryl group; an aryloxy group; an aralkyloxy group; a R.sub.8 R.sub.9 N group wherein R.sub.8 and R.sub.9 represent, respectively and independently, a hydrogen atom, an alkyl group, an alkenyl group an aralkyl group, or an acyl group; a nitro group; or a R.sub.10 OOC group wherein R.sub.10 represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group; ##STR2## wherein R.sub.1, R.sub.2 and R.sub.4 to R.sub.7 represent, respectively, the same constituents as described in formula (I).
摘要翻译：本发明涉及一种制备喹啉酮衍生物的简单方法，其作为药物是有效的，例如用作治疗过敏性疾病等的药剂; 在该方法中作为中间体有效的新型酰胺衍生物; 按照该方法得到的新型喹啉酮衍生物; 以及含有与活性成分相同的喹啉酮衍生物和/或其生理盐的抗过敏剂。喹啉酮衍生物由以下通式（II）表示; 该方法的特征在于将由下式（I）表示的酰胺衍生物与碱性试剂反应，然后分子内环形成：其中R 1表示氢原子，烷基，含有羟基的烷基烯基或芳基; R2表示烷基，烯基，芳基或芳烷基; R3代表活性羧基; 和R 4至R 7分别独立地表示氢原子; 羟基; 烷基; 烷氧基烯基; 烯氧基; 芳基; 芳氧基; 芳烷氧基; R8R9N基，其中R8和R9分别独立地表示氢原子，烷基，烯基，芳烷基或酰基; 硝基; 或R10OOC基，其中R10表示氢原子，烷基，烯基，芳基或芳烷基; 其中R1，R2和R4至R7分别表示与式（I）中所述相同的组分。

7. 发明授权

US06271416B1 Quinolinone derivative, method for preparing the same, and anti-allergic agent 有权
标题翻译：喹啉酮衍生物，其制备方法和抗过敏剂
公开(公告)号：US06271416B1
公开(公告)日：2001-08-07
申请号：US09595909
申请日：2000-06-20
申请人： Hidetsugu Takagaki , Shinobu Yamaguchi , Masayoshi Abe , Mitsuru Sakai , Osamu Misumi
发明人： Hidetsugu Takagaki , Shinobu Yamaguchi , Masayoshi Abe , Mitsuru Sakai , Osamu Misumi
IPC分类号： C07C22900
CPC分类号： C07D215/22 , C07C235/16 , C07D215/38 , C07D215/40 , C07D215/48 , C07D401/12 , C07D405/04 , C07D405/06
摘要： The present invention relates to a simple method for preparing a quinolinone derivative, which is effective as a medicine, e.g., as an agent for treating allergic diseases and the like; novel amide derivatives effective as an intermediate in the method, novel quinolinone derivatives obtained according to the method; and an anti-allergic agent containing a quinolinone derivative and/or physiological salt of the same as the active ingredients. The quinolinone derivative is expressed by the following general formula (II); and the method is characterized in that an amide derivative, expressed by the following general formula (I), is reacted with a basic agent, followed by intramolecular ring formation: General Formula (I) [wherein, R1 represents a hydrogen atom, an alkyl group, an alkyl group containing a hydroxyl group, an alkenyl group, or an aryl group; R2 represents an alkyl group, an alkenyl group, an aryl group, or an aralkyl group; R3 represents a reactive carboxyl group; and R4 to R7 represent, respectively and independently, a hydrogen atom, a hydroxyl group, an alkyl group, an alkoxy group, an alkenyl group, an alkenyloxy group, an aryl group, an aryloxy group, an aralkyloxy group, a R8R9N group (wherein, R8 and R9 represent, respectively and independently, a hydrogen atom, an alkyl group, an alkenyl group, an aralkyl group, or an acyl group), a nitro group, or a R10OOC group (wherein, R10 represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group)]. General Formula (II) [wherein, R1, R2 and R4 to R7 represent, respectively, the same constituents as described in general formula (I)].
摘要翻译：本发明涉及一种制备喹啉酮衍生物的简单方法，其作为药物是有效的，例如用作治疗过敏性疾病等的药剂; 该方法中作为中间体有效的新型酰胺衍生物，按照该方法得到的新型喹啉酮衍生物; 以及含有与活性成分相同的喹啉酮衍生物和/或其生理盐的抗过敏剂。喹啉酮衍生物由以下通式（II）表示; 该方法的特征在于将由以下通式（I）表示的酰胺衍生物与碱性试剂反应，然后分子内环形成：通式（I）[其中，R 1表示氢原子，烷基基团，含有羟基，烯基或芳基的烷基; R2表示烷基，烯基，芳基或芳烷基; R3代表活性羧基; R 4〜R 7分别独立地表示氢原子，羟基，烷基，烷氧基，烯基，烯氧基，芳基，芳氧基，芳烷氧基，R8R9N基（其中，R8和R9分别独立地表示氢原子，烷基，烯基，芳烷基或酰基），硝基或R10OOC基（其中，R10表示氢原子，烷基，烯基，芳基或芳烷基）]通式（II）[其中，R1，R2和R4至R7分别表示与通式（I）中所述相同的组分] 。

8. 发明授权

US09086531B2 Plastic polarized lens, method for producing the same, and polarized film 有权
标题翻译：塑料偏光镜片，其制造方法和偏光膜
公开(公告)号：US09086531B2
公开(公告)日：2015-07-21
申请号：US13813312
申请日：2011-08-10
申请人： Akinori Ryu , Seiichi Kobayashi , Hiroyuki Kamio , Yoshiharu Kobayashi , Mitsuru Sakai , Yoshimitsu Aiiso
发明人： Akinori Ryu , Seiichi Kobayashi , Hiroyuki Kamio , Yoshiharu Kobayashi , Mitsuru Sakai , Yoshimitsu Aiiso
IPC分类号： G02B1/08 , B29D11/00 , C09B47/00 , G02B1/04 , G02B5/30 , B29C39/10 , B29C39/12 , B29C33/10 , B29K75/00
CPC分类号： G02B1/08 , B29C33/10 , B29C39/10 , B29C39/12 , B29K2075/00 , B29K2995/0034 , C09B47/00 , G02B1/041 , G02B5/3033 , G02B2207/113 , C08L81/00 , C08L75/04
摘要： The plastic polarized lens (10) of the present invention contains a polarized film (12) and layers (resin layers) (14a and 14b) comprising a thiourethane-based resin stacked over both surfaces of the polarized film (12), and the polarized film contains an organic coloring compound represented by the following general formula (1).
摘要翻译：本发明的塑料偏光透镜（10）包含偏振膜（12）和层叠在偏振膜（12）的两个表面上的硫代氨基甲酸酯类树脂的层（树脂层）（14a和14b），并且偏振膜包含由以下通式（1）表示的有机着色化合物。

9. 发明授权

US08476740B2 Sheet for protecting surface of semiconductor wafer, semiconductor device manufacturing method and semiconductor wafer protection method using sheet 有权
标题翻译：用于保护半导体晶片表面的片，半导体器件制造方法和使用片的半导体晶片保护方法
公开(公告)号：US08476740B2
公开(公告)日：2013-07-02
申请号：US13520110
申请日：2011-05-31
申请人： Eiji Hayashishita , Yoshihisa Saimoto , Makoto Kataoka , Katsutoshi Ozaki , Mitsuru Sakai
发明人： Eiji Hayashishita , Yoshihisa Saimoto , Makoto Kataoka , Katsutoshi Ozaki , Mitsuru Sakai
IPC分类号： H01L23/58 , H01L21/30 , H01L21/46 , H01L21/00 , B32B9/00 , B32B33/00
CPC分类号： H01L21/67132 , Y10T428/1471
摘要： To provide a semiconductor wafer surface protection sheet having good adhesion to irregularities on a patterned surface of a semiconductor wafer and having good peelability after wafer grinding. Specifically, a semiconductor wafer surface protection sheet is provided that includes a base layer having a tensile elasticity at 25° C., E(25), of 1 GPa or more; a resin layer A that satisfies the condition EA(60)/EA(25)
摘要翻译：提供对半导体晶片的图案化表面上的凹凸具有良好粘附性并且在晶片研磨之后具有良好剥离性的半导体晶片表面保护片。具体地说，提供一种半导体晶片表面保护片，其包括在25℃，E（25），1GPa以上的拉伸弹性的基层; 满足条件EA（60）/ EA（25）<0.1的树脂层A，其中EA（25）为25℃时的拉伸弹性，EA（60）为60℃时的拉伸弹性， EA（60）为0.005MPa〜1MPa; 和EB（60）大于EA（60）的树脂层B，EB（60）为1MPa以上，厚度为0.1μm以上且小于100μm的EB（60））树脂层A.

10. 发明授权

US08000213B2 Optical disc recording/reproducing apparatus 有权
标题翻译：光盘记录/重放装置
公开(公告)号：US08000213B2
公开(公告)日：2011-08-16
申请号：US12667092
申请日：2008-06-27
申请人： Dai Ichiryu , Mitsuru Sakai
发明人： Dai Ichiryu , Mitsuru Sakai
IPC分类号： G11B7/00
CPC分类号： G11B7/00745 , G11B7/0053 , G11B7/00718
摘要： There is provided an optical disc recording/reproducing apparatus which can reduce the chip size using the high-miniaturization process and can enhance the detection accuracy. A signal which is obtained by amplitude-adjusting a header region in a reproduced signal detected by an optical pickup (1) is digitized, and peak detection or bottom detection from the reproduced signal in each of a first section and a second section in the header region is performed by detection circuits (9) to (12), respectively. Then, amplitude data in the first section and the second section are obtained by subtracters (13) and (14) from the detected values in the respective detection circuits. A difference in amplitude between the first section and the second section in the header region is obtained by a subtracter (15) based on the amplitude data, and the amplitude difference is outputted as an off-track error signal. The respective detection circuits (9) to (12) perform detection operations in the first and second sections, and hold the detection operations in the sections other than the first and second sections.
摘要翻译：提供了一种光盘记录/再现装置，其可以使用高度小型化处理来减小芯片尺寸，并且可以提高检测精度。通过对由光学拾取器（1）检测到的再现信号中的标题区进行幅度调整而获得的信号被数字化，并且在标题中的第一部分和第二部分中的每一个中的再现信号中进行峰值检测或底部检测区域由检测电路（9）〜（12）分别进行。然后，通过减法器（13）和（14）从各个检测电路中的检测值获得第一部分和第二部分中的幅度数据。通过基于幅度数据的减法器（15）获得标题区域中的第一部分和第二部分之间的幅度差异，并且将幅度差作为偏离磁道误差信号输出。各检测电路（9）至（12）执行第一和第二部分的检测操作，并且将检测操作保持在除第一和第二部分之外的部分中。

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