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    • 3. 发明授权
    • Semiconductor light emitting device and light emitting module
    • 半导体发光器件和发光模块
    • US08648375B2
    • 2014-02-11
    • US13601336
    • 2012-08-31
    • Hideto FuruyamaAkihiro KojimaMiyoko ShimadaYosuke AkimotoHideyuki Tomizawa
    • Hideto FuruyamaAkihiro KojimaMiyoko ShimadaYosuke AkimotoHideyuki Tomizawa
    • H01L33/00
    • H01L33/505
    • According to one embodiment, a semiconductor light emitting device includes: a semiconductor layer including a first and second surfaces, and a light emitting layer; a p-side electrode provided on the second surface; an n-side electrode provided on the second surface; a first insulating film covering the p-side and the n-side electrodes; a p-side wiring section electrically connected to the p-side electrode through the first insulating film; an n-side wiring section electrically connected to the n-side electrode through the first insulating film; and a phosphor layer provided on the first surface. The phosphor layer has an upper surface and an oblique surface, the oblique surface forming an obtuse angle with the upper surface and inclined with respect to the first surface. Thickness of the phosphor layer immediately below the oblique surface is smaller than thickness of the phosphor layer immediately below the upper surface.
    • 根据一个实施例,半导体发光器件包括:包括第一和第二表面的半导体层和发光层; 设置在第二表面上的p侧电极; 设置在所述第二表面上的n侧电极; 覆盖p侧和n侧电极的第一绝缘膜; 通过第一绝缘膜电连接到p侧电极的p侧布线部分; 通过第一绝缘膜与n侧电极电连接的n侧配线部; 以及设置在第一表面上的荧光体层。 荧光体层具有上表面和倾斜表面,倾斜表面与上表面形成钝角并相对于第一表面倾斜。 斜面正下方的荧光体层的厚度小于上表面正下方的荧光体层的厚度。
    • 6. 发明申请
    • SEMICONDUCTOR LIGHT EMITTING DEVICE AND LIGHT EMITTING MODULE
    • 半导体发光器件和发光模块
    • US20130313581A1
    • 2013-11-28
    • US13601336
    • 2012-08-31
    • Hideto FuruyamaAkihiro KojimaMiyoko ShimadaYosuke AkimotoHideyuki Tomizawa
    • Hideto FuruyamaAkihiro KojimaMiyoko ShimadaYosuke AkimotoHideyuki Tomizawa
    • H01L33/50H01L33/08
    • H01L33/505
    • According to one embodiment, a semiconductor light emitting device includes: a semiconductor layer including a first and second surfaces, and a light emitting layer; a p-side electrode provided on the second surface; an n-side electrode provided on the second surface; a first insulating film covering the p-side and the n-side electrodes; a p-side wiring section electrically connected to the p-side electrode through the first insulating film; an n-side wiring section electrically connected to the n-side electrode through the first insulating film; and a phosphor layer provided on the first surface. The phosphor layer has an upper surface and an oblique surface, the oblique surface forming an obtuse angle with the upper surface and inclined with respect to the first surface. Thickness of the phosphor layer immediately below the oblique surface is smaller than thickness of the phosphor layer immediately below the upper surface.
    • 根据一个实施例,半导体发光器件包括:包括第一和第二表面的半导体层和发光层; 设置在第二表面上的p侧电极; 设置在所述第二表面上的n侧电极; 覆盖p侧和n侧电极的第一绝缘膜; 通过第一绝缘膜电连接到p侧电极的p侧布线部分; 通过第一绝缘膜与n侧电极电连接的n侧配线部; 以及设置在第一表面上的荧光体层。 荧光体层具有上表面和倾斜表面,倾斜表面与上表面形成钝角并相对于第一表面倾斜。 斜面正下方的荧光体层的厚度小于上表面正下方的荧光体层的厚度。
    • 10. 发明授权
    • Nonhuman model animal unresponsive to immunopotentiating synthetic compound
    • 非人类模型动物对免疫增强合成化合物无反应
    • US07608750B2
    • 2009-10-27
    • US10496501
    • 2002-11-22
    • Shizuo AkiraHideyuki TomizawaTakashi Yamaoka
    • Shizuo AkiraHideyuki TomizawaTakashi Yamaoka
    • A01K67/00A01K67/027C12N15/00
    • C07K14/705A01K67/0276A01K2217/075A01K2227/105A01K2267/0337C12N15/8509
    • The present invention relates to provide a non-human animal model unresponsive to a synthetic compound wherein a gene function encoding TLR7 that recognizes an immunopotentiating synthetic compound such as imidazoquinoline lacks on is genomic locus. Whole or part of a gene fragment of a gene site including an intracellular region and a transmembrane region of a TLR7 gene obtained from a mouse gene library is replaced by a plasmid including poly A signal and a marker gene to construct a targeting vector. Then, this targeting vector is linearized and transferred into embryonic stem cells. The target embryonic stem cells wherein the TLR7 gene function is deleted are microinjected into a mouse blastocyst to generate a chimeric mouse. Then, this chimeric mouse is crossed with a wild-type mouse to generate a heterozygote mouse. Next, the heterozygote mice are intercrossed to obtain a TLR7 knockout mouse.
    • 本发明涉及提供对合成化合物无反应的非人动物模型,其中编码识别免疫增强合成化合物如咪唑并喹啉的TLR7的基因功能是基因组座位。 包含从小鼠基因文库获得的TLR7基因的细胞内区域和跨膜区的基因位点的整个或部分基因片段被包含polyA信号和标记基因的质粒所取代,以构建靶向载体。 然后,将该靶向载体线性化并转移到胚胎干细胞中。 将其中缺失TLR7基因功能的靶胚胎干细胞微注射到小鼠胚泡中以产生嵌合小鼠。 然后,将该嵌合小鼠与野生型小鼠杂交以产生杂合子小鼠。 接下来,杂交小鼠被交叉以获得TLR7敲除小鼠。