会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 8. 发明申请
    • Axially Asymmetric Phosphorus Compound and Production Method Thereof
    • 轴向不对称磷化合物及其制备方法
    • US20090227805A1
    • 2009-09-10
    • US12396751
    • 2009-03-03
    • Ken TanakaGoushi NishidaTohru YokozawaYukinori Yusa
    • Ken TanakaGoushi NishidaTohru YokozawaYukinori Yusa
    • C07F9/655
    • C07F9/5027C07F9/5059C07F9/65517
    • Problem to be Solved: To provide an axially asymmetric optically active biarylphosphorus compound that can easily produced without the step of optical resolution which was almost indispensable in conventional methods. Solution: A method for producing an axially asymmetric phosphorus compound represented by the general formula (1), comprising a cycloaddition reaction of a compound having a triple bond with the use of a catalyst containing rhodium metal and an optically active bisphosphine. (In the formula, J is an oxygen atom, a sulfur atom or BH3; R1 and R2 independently are an alkyl, cycloalkyl, aryl, alkoxy and aryloxy group; a1 and a2 independently are 0 or 1; R3 to R10 independently are an alkyl, cycloalkyl, aryl, alkoxy and aryloxy group; two among R3 to R10 may form a ring; and * is axial asymmetry.)
    • 要解决的问题:提供一种轴向不对称光学活性联芳基磷化合物,其可以容易地在没有光学拆分步骤的情况下产生,这在常规方法中几乎不可缺少。 溶液:用于制备由通式(1)表示的轴向不对称磷化合物的方法,其包括使用含铑金属和光学活性双膦的催化剂的具有三重键的化合物的环加成反应。 (式中,J为氧原子,硫原子或BH 3; R1和R2分别独立地为烷基,环烷基,芳基,烷氧基和芳氧基; a1和a2独立地为0或1; R3至R10独立地为烷基 ,环烷基,芳基,烷氧基和芳氧基; R3至R10中的两个可以形成环; *是轴不对称的)