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1. 发明授权

US6166215A Process for producing guanidine derivatives, intermediates therefor and their production 有权
标题翻译：制备胍衍生物的方法，其中间体及其制备方法
公开(公告)号：US6166215A
公开(公告)日：2000-12-26
申请号：US391463
申请日：1999-09-08
申请人： Hideki Uneme , Hitoshi Ishizuka
发明人： Hideki Uneme , Hitoshi Ishizuka
IPC分类号： C07D209/48 , C07D213/61 , C07D277/28 , C07D277/32 , C07D277/04
CPC分类号： C07D209/48 , C07D213/61 , C07D277/32
摘要： A process for producing the compound [I] or a salt thereof having excellent pesticidal activity as shown in the following schema. ##STR1##
摘要翻译：具有如下模式所示的具有优良杀虫活性的化合物[I]或其盐的方法。

2. 发明授权

US6008363A Process for producing guanidine derivatives, intermediates therefor and their production 失效
标题翻译：制备胍衍生物的方法，其中间体及其制备方法
公开(公告)号：US6008363A
公开(公告)日：1999-12-28
申请号：US793097
申请日：1997-02-21
申请人： Hideki Uneme , Masato Konobe , Hitoshi Ishizuka , Yasuo Kamiya
发明人： Hideki Uneme , Masato Konobe , Hitoshi Ishizuka , Yasuo Kamiya
IPC分类号： C07D209/48 , C07D213/61 , C07D277/28 , C07D277/32 , C07C277/08 , C07C273/18 , C07C279/36 , C07D213/38
CPC分类号： C07D209/48 , C07D213/61 , C07D277/32
摘要： A process for producing the compound [I] or a salt thereof having excellent pesticidal activity as shown in the following schema. ##STR1##
摘要翻译： PCT No.PCT / JP96 / 01694 Sec。 371日期1997年2月21日 102（e）1997年2月21日PCT PCT 1996年6月19日PCT公布。公开号WO97 / 00867 日本1997年1月9日制备具有优异杀虫活性的化合物[I]或其盐的方法，如下列模式所示。

3. 发明授权

US5256679A Substituted guanidine derivatives, their preparation and use 失效
标题翻译：取代的胍衍生物，其制备和用途
公开(公告)号：US5256679A
公开(公告)日：1993-10-26
申请号：US745245
申请日：1991-08-14
申请人： Isao Minamida , Yasuyuki Kando , Hitoshi Ishizuka , Tetsuo Okauchi , Hideki Uneme
发明人： Isao Minamida , Yasuyuki Kando , Hitoshi Ishizuka , Tetsuo Okauchi , Hideki Uneme
IPC分类号： A01N51/00 , A01N43/40 , A01N43/78 , A01N43/84 , A01N47/44 , C07C255/58 , C07C277/08 , C07C279/34 , C07C335/40 , C07D205/10 , C07D207/40 , C07D207/404 , C07D207/44 , C07D207/448 , C07D209/48 , C07D211/88 , C07D213/16 , C07D213/36 , C07D213/61 , C07D213/69 , C07D213/75 , C07D241/12 , C07D277/12 , C07D277/20 , C07D277/28 , C07D277/32 , C07D277/34 , C07D277/38 , C07D277/48 , C07D417/12 , C07D213/26 , C07D277/30
CPC分类号： C07D207/404 , A01N51/00 , C07C255/58 , C07C335/40 , C07D205/10 , C07D207/448 , C07D209/48 , C07D211/88 , C07D213/61 , C07D213/69 , C07D241/12 , C07D277/32 , C07D277/34 , C07D417/12
摘要： Novel substituted nitroguanidine derivatives and salts thereof having the following formula: ##STR1## wherein R.sup.1 is a substituted or unsubstituted heterocyclic group; R.sup.2 is a group attached through a sulfur atom, a group attached through a phosphorus atom, cyano, --CO--OR.sup.6 wherein R.sup.6 is a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or --CO--NR.sup.7 R.sup.8 wherein R.sup.7 and R.sup.8, which are the same or different, are each independently hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or R.sup.7 and R.sup.8, taken together with the nitrogen atom to which they are attached are a cyclic amino group; R.sup.3 is hydrogen, a substituted or unsubstituted hydrocarbon group (except for one substituted with an oxo group at the binding site), a group attached through a sulfur atom, a group attached through a phosphorus atom, cyano, --CO--R.sup.9 wherein R.sup.9 is hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, --CO--OR.sup.10 wherein R.sup.10 is a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or --CO--NR.sup.11 R.sup.12 wherein R.sup.11 and R.sup.12, which are the same or different, are each independently hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or R.sup.11 and R.sup.12, taken together with the nitrogen atom to which they are attached are a cyclic amino group; and R.sup.4 is hydrogen or a lower alkyl group; which have unexpectedly potent pesticidal activity and very low toxicity.

4. 发明授权

US08568490B2 Liquid detergent composition 有权
标题翻译：液体洗涤剂组合物
公开(公告)号：US08568490B2
公开(公告)日：2013-10-29
申请号：US13129590
申请日：2009-11-19
申请人： Toshio Miyake , Hitoshi Ishizuka , Kohei Nishida , Ayako Kita
发明人： Toshio Miyake , Hitoshi Ishizuka , Kohei Nishida , Ayako Kita
IPC分类号： C11D1/722 , C11D1/02 , C11D3/30 , C11D3/43 , B08B3/04
CPC分类号： C11D1/83 , C11D1/722 , C11D3/43
摘要： The invention provides a liquid detergent composition containing (a) a nonionic surfactant obtained by adding ethylene oxide and an alkylene oxide with from 3 to 5 carbon atoms to a compound represented by R—OH (wherein R represents an alkyl group or an alkenyl group with from 8 to 18 carbon atoms) under a specified condition, (b) an anionic surfactant and (c) a water-miscible organic solvent in specified ratios, respectively.
摘要翻译：本发明提供了一种液体洗涤剂组合物，其含有（a）通过将环氧乙烷和具有3至5个碳原子的环氧烷加成到由R-OH表示的化合物（其中R表示烷基或烯基与 8至18个碳原子），（b）阴离子表面活性剂和（c）分别具有特定比例的水混溶性有机溶剂。

5. 发明授权

US07863234B2 Liquid detergent composition 有权
标题翻译：液体洗涤剂组合物
公开(公告)号：US07863234B2
公开(公告)日：2011-01-04
申请号：US12084264
申请日：2006-12-26
申请人： Masataka Maki , Yuichiro Tase , Hitoshi Ishizuka , Nobuyoshi Yamaguchi
发明人： Masataka Maki , Yuichiro Tase , Hitoshi Ishizuka , Nobuyoshi Yamaguchi
IPC分类号： C11D1/72 , C11D1/722 , C11D3/04 , C11D3/20 , C11D3/39
CPC分类号： C11D3/3947 , C11D1/72 , C11D3/0047 , C11D3/042 , C11D3/046 , C11D3/2065 , C11D3/221 , C11D3/3907 , C11D17/0017 , D06L4/12
摘要： The present invention relates to a liquid detergent composition containing (a) hydrogen peroxide or a compound forming hydrogen peroxide in water, 0.1 to 10 mass % of (b) a bleaching activator, 45 to 80 mass % of (c) a nonionic surfactant, (d) water, (e) at least one or more compounds selected from boric acid, borax and borate, and (f) a polyol compound, said liquid detergent composition having a pH value of 4 to 7 at 20° C.
摘要翻译：本发明涉及一种液体洗涤剂组合物，其含有（a）过氧化氢或在水中形成过氧化氢的化合物，（b）漂白活化剂为0.1〜10质量％，（c）非离子表面活性剂为45〜80质量％（d）水，（e）至少一种或多种选自硼酸，硼砂和硼酸盐的化合物和（f）多元醇化合物，所述液体洗涤剂组合物在20℃下的pH值为4-7。

6. 发明授权

US09339487B2 Dry powder pharmaceutical composition for inhalation 有权
标题翻译：干粉药物组合物用于吸入
公开(公告)号：US09339487B2
公开(公告)日：2016-05-17
申请号：US13132599
申请日：2009-12-24
申请人： Makoto Miyajima , Shigeru Noda , Kazuhiro Inoue , Michiko Kumon , Katsuyasu Ishida , Hitoshi Ishizuka
发明人： Makoto Miyajima , Shigeru Noda , Kazuhiro Inoue , Michiko Kumon , Katsuyasu Ishida , Hitoshi Ishizuka
IPC分类号： A61K31/351 , A61K9/14 , A61P31/16 , C07D309/28 , A61K9/00
CPC分类号： A61K31/351 , A61K9/0075 , A61K9/14 , Y10T428/2982
摘要： There is provided a dry powder pharmaceutical composition for inhalation useful for preventing and/or treating influenza virus infections contains as a medicinal component a compound represented by formula (I): and optionally a compound represented by formula (II): a pharmacologically acceptable salt thereof, or a hydrate thereof.
摘要翻译：提供一种用于预防和/或治疗流感病毒感染的干粉药物组合物，含有作为药用成分的由式（I）表示的化合物：和任选的由式（II）表示的化合物：其药理学上可接受的盐，或其水合物。

7. 发明申请

US20100308260A1 LIQUID BLEACHING AGENT COMPOSITION 审中-公开
标题翻译：液体漂白剂组合物
公开(公告)号：US20100308260A1
公开(公告)日：2010-12-09
申请号：US12864627
申请日：2009-02-05
申请人： Masataka Maki , Yuichiro Tase , Hitoshi Ishizuka , Nobuyoshi Yamaguchi
发明人： Masataka Maki , Yuichiro Tase , Hitoshi Ishizuka , Nobuyoshi Yamaguchi
IPC分类号： C11D3/395
CPC分类号： C11D1/83 , C11D1/72 , C11D3/0047 , C11D3/042 , C11D3/046 , C11D3/3947
摘要： The present invention relates to a liquid bleaching agent composition containing (a) hydrogen peroxide, (b1) a nonionic surfactant, (b2) an anionic surfactant, (c) a bleaching activator, (d) at least one compound selected from boric acid, borax and a borate, and (e) a compound having one or more groups in which a hydroxyl group is present on each of the adjacent carbon atoms to each other, wherein the respective contents of component (b1), component (b2) and the mass ratio of component (b2) to component (b1) are all within a specific range and the composition has pH 2.5-4.5 at 20° C.
摘要翻译：本发明涉及含有（a）过氧化氢，（b1）非离子表面活性剂，（b2）阴离子表面活性剂，（c）漂白活化剂，（d）至少一种选自硼酸，硼酸盐和硼酸盐，和（e）具有一个或多个相邻碳原子上存在羟基的基团的化合物，其中组分（b1），组分（b2）和组分（b2）与组分（b1）的质量比全部在特定范围内，组合物在20℃下的pH为2.5-4.5。

8. 发明申请

US20090249557A1 Liquid Detergent Composition 有权
标题翻译：液体洗涤剂组合物
公开(公告)号：US20090249557A1
公开(公告)日：2009-10-08
申请号：US12084264
申请日：2006-12-26
申请人： Masataka Maki , Yuichiro Tase , Hitoshi Ishizuka , Nobuyoshi Yamaguchi
发明人： Masataka Maki , Yuichiro Tase , Hitoshi Ishizuka , Nobuyoshi Yamaguchi
IPC分类号： D06L1/00 , C11D9/42
CPC分类号： C11D3/3947 , C11D1/72 , C11D3/0047 , C11D3/042 , C11D3/046 , C11D3/2065 , C11D3/221 , C11D3/3907 , C11D17/0017 , D06L4/12
摘要： The present invention relates to a liquid detergent composition containing (a) hydrogen peroxide or a compound forming hydrogen peroxide in water, 0.1 to 10 mass % of (b) a bleaching activator, 45 to 80 mass % of (c) a nonionic surfactant, (d) water, (e) at least one or more compounds selected from boric acid, borax and borate, and (f) a polyol compound, said liquid detergent composition having a pH value of 4 to 7 at 20° C.
摘要翻译：本发明涉及一种液体洗涤剂组合物，其含有（a）过氧化氢或在水中形成过氧化氢的化合物，（b）漂白活化剂为0.1〜10质量％，（c）非离子表面活性剂为45〜80质量％（d）水，（e）至少一种或多种选自硼酸，硼砂和硼酸盐的化合物和（f）多元醇化合物，所述液体洗涤剂组合物在20℃下的pH值为4-7。

9. 发明申请

US20120010118A1 LIQUID DETERGENT COMPOSITION 有权
标题翻译：液体洗涤剂组合物
公开(公告)号：US20120010118A1
公开(公告)日：2012-01-12
申请号：US13257509
申请日：2010-04-16
申请人： Hitoshi Ishizuka , Kyoko Okada , Yoshiyuki Komatsu , Toshio Miyake
发明人： Hitoshi Ishizuka , Kyoko Okada , Yoshiyuki Komatsu , Toshio Miyake
IPC分类号： C11D17/00 , C11D3/60
CPC分类号： C11D1/86 , C11D1/722 , C11D3/43
摘要： The present invention provides a liquid detergent composition containing the following components (a) to (c), wherein the total content of components (a) to (c), (a)+(b)+(c), is 40 to 90% by mass; a mass ratio of components (a) to (b), (a)/(b), is 25/75 to 90/10; and a mass ratio [(a)+(b)]/(c), is 95/5 to 70/30: component (a): 15 to 75% by mass of a nonionic surfactant produced by adding p1 mol of ethylene oxide to a compound represented by R—OH (wherein, R represents a hydrocarbon group having 8 to 18 carbon atoms), then adding q1 mol of an alkylene oxide having 3 to 5 carbon atoms, and then adding p2 mol of ethylene oxide, wherein p1 is the number of 3 to 30, q1 is the number of 1 to 5, and p1+p2 is 14 to 50, component (b): anionic surfactant, component (c): cationic surfactant, component (d): 5 to 40% by mass of water-miscible organic solvent.
摘要翻译：本发明提供含有以下成分（a）〜（c）的液体洗涤剂组合物，其中成分（a）〜（c），（a）+（b）+（c）的总含量为40〜90 质量％组分（a）至（b），（a）/（b）的质量比为25/75至90/10; 质量比[（a）+（b）] /（c）为95/5〜70 / 30:成分（a）：将15质量％与由R-OH表示的化合物（其中，R表示碳原子数为8〜18的烃基），然后加入q1摩尔碳原子数3〜5的烯化氧，然后加入p2摩尔环氧乙烷，其中p1 成分（b）：阴离子表面活性剂，成分（c）：阳离子性表面活性剂，成分（d）：5〜40，数量为3〜30，q1为1〜5，p1 + p2为14〜质量％的水混溶性有机溶剂。

10. 发明申请

US20110256188A1 DRY POWDER PHARMACEUTICAL COMPOSITION FOR INHALATION 有权
标题翻译：干粉用于吸入的药物组合物
公开(公告)号：US20110256188A1
公开(公告)日：2011-10-20
申请号：US13132599
申请日：2009-12-24
申请人： Makoto Miyajima , Shigeru Noda , Kazuhiro Inoue , Michiko Kumon , Katsuyasu Ishida , Hitoshi Ishizuka
发明人： Makoto Miyajima , Shigeru Noda , Kazuhiro Inoue , Michiko Kumon , Katsuyasu Ishida , Hitoshi Ishizuka
IPC分类号： A61K31/351 , A61K9/14 , A61P31/16 , C07D309/28
CPC分类号： A61K31/351 , A61K9/0075 , A61K9/14 , Y10T428/2982
摘要： There is provided a dry powder pharmaceutical composition for inhalation useful for preventing and/or treating influenza virus infections contains as a medicinal component a compound represented by formula (I): and optionally a compound represented by formula (II): , a pharmacologically acceptable salt thereof, or a hydrate thereof.
摘要翻译：提供了一种用于预防和/或治疗流感病毒感染的干粉药物组合物，含有作为药用成分的由式（I）表示的化合物：和任选的由式（II）表示的化合物：药理学上可接受的盐或其水合物。

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