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1. 发明授权

US09603919B2 Method for prophylaxis of influenza using vaccine for intranasal administration 有权
公开(公告)号：US09603919B2
公开(公告)日：2017-03-28
申请号：US13262515
申请日：2010-03-31
申请人： Hideki Hasegawa , Sadao Manabe , Takeshi Tanimoto , Takashi Miyazaki , Taizou Kamishita
发明人： Hideki Hasegawa , Sadao Manabe , Takeshi Tanimoto , Takashi Miyazaki , Taizou Kamishita
IPC分类号： A61K39/145 , A61K39/12 , A61K39/39 , A61K39/00 , A61K38/00 , C07K14/005 , C12N7/00
CPC分类号： A61K39/145 , A61K39/12 , A61K39/39 , A61K2039/525 , A61K2039/5254 , A61K2039/543 , A61K2039/55555 , A61K2039/55561 , A61K2039/58 , A61K2039/6093 , C12N2760/16134
摘要： The present invention provides a vaccine composition for transnasal mucous membrane administration, which contains an influenza virus antigen, polyriboinosinic polyribocytidylic acid (poly (I:C)) or a derivative thereof and a carboxyvinyl polymer. The present invention also provides a prophylactic method of influenza, including a step of administering the vaccine composition at least once to the nasal mucosa of a subject in need thereof.

2. 发明申请

US20120082697A1 METHOD FOR PROPHYLAXIS OF INFLUENZA USING VACCINE FOR INTRANASAL ADMINISTRATION 有权
标题翻译：使用疫苗预防流感病毒进行肠内营养的方法
公开(公告)号：US20120082697A1
公开(公告)日：2012-04-05
申请号：US13262515
申请日：2010-03-31
申请人： Hideki Hasegawa , Sadao Manabe , Takeshi Tanimoto , Takashi Miyazaki , Taizou Kamishita
发明人： Hideki Hasegawa , Sadao Manabe , Takeshi Tanimoto , Takashi Miyazaki , Taizou Kamishita
IPC分类号： A61K39/145 , A61P31/16 , A61P37/04
CPC分类号： A61K39/145 , A61K39/12 , A61K39/39 , A61K2039/525 , A61K2039/5254 , A61K2039/543 , A61K2039/55555 , A61K2039/55561 , A61K2039/58 , A61K2039/6093 , C12N2760/16134
摘要： The present invention provides a vaccine composition for transnasal mucous membrane administration, which contains an influenza virus antigen, polyriboinosinic polyribocytidylic acid (poly (I:C)) or a derivative thereof and a carboxyvinyl polymer. The present invention also provides a prophylactic method of influenza, including a step of administering the vaccine composition at least once to the nasal mucosa of a subject in need thereof.
摘要翻译：本发明提供一种用于经鼻粘膜给药的疫苗组合物，其包含流感病毒抗原，多核糖肌苷酸多核糖胞苷酸（聚（I：C））或其衍生物和羧乙烯基聚合物。本发明还提供了一种流感的预防方法，包括将疫苗组合物至少一次施用于有需要的受试者的鼻粘膜的步骤。

3. 发明申请

US20070219149A1 Novel Vaccine Containing Adjuvant Capable Of Inducing Mucosal Immunity 审中-公开
标题翻译：含有能够诱导黏膜免疫的佐剂的新型疫苗
公开(公告)号：US20070219149A1
公开(公告)日：2007-09-20
申请号：US10567766
申请日：2004-08-10
申请人： Hideki Hasegawa , Takeshi Kurata , Tetsutarou Sata , Masami Moriyama , Shin-ichi Tamura , Takeshi Tanimoto
发明人： Hideki Hasegawa , Takeshi Kurata , Tetsutarou Sata , Masami Moriyama , Shin-ichi Tamura , Takeshi Tanimoto
IPC分类号： A61K48/00 , A61K39/295 , A61K39/12 , A61K39/21 , A61K39/145 , A61K39/165 , A61K39/13 , A61K39/215 , A61K39/02
CPC分类号： A61K39/145 , A61K39/099 , A61K39/12 , A61K39/25 , A61K39/39 , A61K2039/5252 , A61K2039/541 , A61K2039/543 , A61K2039/545 , A61K2039/55544 , A61K2039/55561 , A61K2039/58 , C12N2710/16734 , C12N2760/16134 , C12N2760/16234 , Y02A50/466
摘要： The present invention provides an adjuvant that possesses a greater adjuvant potential than that of a conventional adjuvant, and that is capable of producing a protective reaction across different strains. This problem has been solved by the finding that a double-stranded RNA (for example, Poly(I:C)) unexpectedly exhibits the above capability when used in combination with a subunit antigen. Accordingly, the present invention provides a vaccine for mucosal administration containing A) a double-stranded RNA and B) a subunit antigen or inactivated antigen of a pathogen.
摘要翻译：本发明提供了具有比常规佐剂更大的佐剂潜力的佐剂，并且能够产生不同菌株的保护性反应。当与亚单位抗原组合使用时，双链RNA（例如，Poly（I：C））意外地表现出上述能力，已经解决了这个问题。因此，本发明提供了一种用于粘膜给药的疫苗，其包含A）双链RNA和B）亚单位抗原或病原体的灭活抗原。

4. 发明授权

US5907344A Image forming apparatus with image tone adjusting function 失效
标题翻译：具有图像色调调节功能的图像形成装置
公开(公告)号：US5907344A
公开(公告)日：1999-05-25
申请号：US76705
申请日：1998-05-13
申请人： Takeshi Tanimoto , Youji Houki , Tsutomu Nagatomi , Hirofumi Nakayasu , Masakazu Kinoshita
发明人： Takeshi Tanimoto , Youji Houki , Tsutomu Nagatomi , Hirofumi Nakayasu , Masakazu Kinoshita
IPC分类号： G03G15/00 , G03G15/04 , G03G15/043 , H04N1/407 , G03G15/01
CPC分类号： H04N1/4078 , G03G15/5058 , G03G2215/00046 , G03G2215/00063
摘要： An image forming apparatus includes an exposure unit forming a latent image using a light from a light source, a developing unit forming a toner image by visualizing the latent image using a toner, a detector outputting a detection signal by optically detecting an amount of toner of the toner image, a memory storing an optimum value of the detection signal output from the detector with respect to a light emission time of the light source, with respect to a plurality of light emission times of the light source to thereby store a plurality optimum values, and a control unit controlling the light emission time of the light source by calculating a light emission time corresponding to a value of the detection signal output from the detector based on the plurality of light emission times stored in the memory.
摘要翻译：图像形成装置包括使用来自光源的光形成潜像的曝光单元，通过使用调色剂使潜像可视化而形成调色剂图像的显影单元，通过光学检测调色剂的量的光学检测器输出检测信号的检测器调色剂图像，相对于光源的多个发光时间存储从检测器输出的检测信号相对于光源的发光时间的最佳值的存储器，从而存储多个最佳值以及控制单元，通过基于存储在存储器中的多个发光次数计算与从检测器输出的检测信号的值对应的发光时间来控制光源的发光时间。

5. 发明授权

US07626900B2 Optical pickup and disk drive apparatus 失效
标题翻译：光学拾取和磁盘驱动装置
公开(公告)号：US07626900B2
公开(公告)日：2009-12-01
申请号：US10943858
申请日：2004-09-20
申请人： Takeshi Tanimoto
发明人： Takeshi Tanimoto
IPC分类号： G11B7/00
CPC分类号： G11B7/1353 , G11B7/0903 , G11B7/0953 , G11B2007/0006
摘要： In an optical pickup for irradiating a laser beam emitted from a photoemission element on a disk-like recording medium through an objective lens, there is provided a diffraction element including a first region for splitting the laser beam emitted from the photoemission element into a main beam and a pair of first sub-beams and a second region for splitting the laser into a main beam and a pair of second sub-beams, wherein a following relation hold or approximately hold: (2n−1)×P/2, where D is a distance between a spot center of the first sub-beam and a spot center of the second sub-beam, the spots being formed on a recording surface of the disk-like recording medium spaced in a substantially radial direction of the disk-like recording medium, n is a natural number, and P is a track pitch of the disk-like recording medium.
摘要翻译：在通过物镜将从光电子发射元件发射的激光束照射在盘状记录介质上的光学拾取器中，提供了一种衍射元件，其包括：第一区域，用于将从光电子发射元件发射的激光束分裂成主光束以及一对第一子光束和第二区域，用于将激光分割为主光束和一对第二子光束，其中以下关系成立或保持：（2n-1）×P / 2，其中D为所述第一子光束的光斑中心与所述第二子光束的光点中心之间的距离，所述光斑形成在所述盘状记录介质的记录表面上，所述记录表面沿盘状记录的大致径向方向间隔开介质，n是自然数，P是盘状记录介质的轨道间距。

6. 发明授权

US07085526B2 Image forming method and image forming apparatus 失效
标题翻译：图像形成方法和图像形成装置
公开(公告)号：US07085526B2
公开(公告)日：2006-08-01
申请号：US10484964
申请日：2001-07-30
申请人： Takeshi Tanimoto
发明人： Takeshi Tanimoto
IPC分类号： G03G15/16 , G03G15/00
CPC分类号： G03G15/167 , G03G2215/00459 , G03G2215/1614
摘要： An apparatus and a method for forming an image is provided that uses a contact type transfer member and a retract mechanism so as to transfer a toner image onto a continuous medium, performs the transfer process stably onto various continuous media and reduces unnecessary transfer of toner from the contact type transfer member to the continuous medium.The unnecessary transfer of toner may be caused by a concentration of contact stress when the contact type transfer member (16), which is moved by a retract mechanism, contacts with the continuous medium (25). To dissipate the contact stress, the transfer member (16) contacts with the continuous medium (25) while the continuous medium (25) is steadily conveyed and the transfer member is steadily rotated. Accordingly, the transfer of the toner from the transfer member (16) to the continuous medium (25) may be reduced. Furthermore, the friction at the contact line may be reduced and thus staining of the continuous medium may be further reduced.
摘要翻译：提供一种用于形成图像的装置和方法，其使用接触型转印构件和缩回机构，以将调色剂图像转印到连续介质上，将转印过程稳定地进行到各种连续介质上，并且减少不必要的调色剂转印接触型转印构件连续介质。当通过缩回机构移动的接触型转印构件（16）与连续介质（25）接触时，调色剂的不必要的转印可能由接触应力的集中引起。为了消散接触应力，传递构件（16）与连续介质（25）接触，而连续介质（25）稳定地传送并且传送构件稳定地旋转。因此，可以减少调色剂从转印部件（16）到连续介质（25）的转印。此外，可以减少接触线处的摩擦，从而可以进一步降低连续介质的污染。

7. 发明授权

US07030951B2 Apparatus and method for displaying image 失效
公开(公告)号：US07030951B2
公开(公告)日：2006-04-18
申请号：US11081200
申请日：2005-03-16
申请人： Yoshio Suzuki , Sou Miyasaka , Yoshiki Shirochi , Takeshi Tanimoto
发明人： Yoshio Suzuki , Sou Miyasaka , Yoshiki Shirochi , Takeshi Tanimoto
IPC分类号： G02F1/1335
CPC分类号： H04N9/3105 , G02F1/133526 , G02F1/13363 , G02F1/133632 , G02F2001/133567
摘要： Provided is a projection type liquid crystal display apparatus, which can improve black-level display and thus can display a higher-contrast image as compared to the related art. An optical compensator is located on the light exit side with respect to the liquid crystal display device so as to compensate for the optical phase difference caused by liquid crystal molecules in a light-entry-side region of the liquid crystal layer. As the optical compensator is located on the light exit side with respect to the liquid crystal display device, birefringence, caused by the liquid crystal molecules present in the light-entry-side region, is compensated for without being influenced by a microlenses provided in the liquid crystal plane. Consequently, the apparatus can improve the black-level display and thus can display a higher-contrast image as compared to the related art. Further, a phase difference caused by the birefringence of the nematic liquid crystal molecule is compensated for by using a substance having properties optically opposite to the positive crystal, namely, a substance having birefringence equivalent to birefringence of a negative crystal.

8. 发明申请

US20050157235A1 Apparatus and method for displaying image 失效
标题翻译：用于显示图像的装置和方法
公开(公告)号：US20050157235A1
公开(公告)日：2005-07-21
申请号：US11081200
申请日：2005-03-16
申请人： Yoshio Suzuki , Sou Miyasaka , Yoshiki Shirochi , Takeshi Tanimoto
发明人： Yoshio Suzuki , Sou Miyasaka , Yoshiki Shirochi , Takeshi Tanimoto
IPC分类号： G02F1/1335 , G02F1/13363 , H04N9/31
CPC分类号： H04N9/3105 , G02F1/133526 , G02F1/13363 , G02F1/133632 , G02F2001/133567
摘要： Provided is a projection type liquid crystal display apparatus, which can improve black-level display and thus can display a higher-contrast image as compared to the related art. An optical compensator is located on the light exit side with respect to the liquid crystal display device so as to compensate for the optical phase difference caused by liquid crystal molecules in a light-entry-side region of the liquid crystal layer. As the optical compensator is located on the light exit side with respect to the liquid crystal display device, birefringence, caused by the liquid crystal molecules present in the light-entry-side region, is compensated for without being influenced by a microlenses provided in the liquid crystal plane. Consequently, the apparatus can improve the black-level display and thus can display a higher-contrast image as compared to the related art. Further, a phase difference caused by the birefringence of the nematic liquid crystal molecule is compensated for by using a substance having properties optically opposite to the positive crystal, namely, a substance having birefringence equivalent to birefringence of a negative crystal.
摘要翻译：提供一种投影型液晶显示装置，与现有技术相比，可以改善黑色级显示，因此可以显示较高对比度的图像。光补偿器相对于液晶显示装置位于光出射侧，以补偿由液晶层的光入射区域中的液晶分子引起的光学相位差。由于光学补偿器相对于液晶显示装置位于光出射侧，因此存在于入射侧区域中的液晶分子引起的双折射被补偿，而不受设置在光入射侧区域中的微透镜的影响液晶平面。因此，与现有技术相比，该装置可以改善黑电平显示，因此可以显示较高对比度的图像。此外，通过使用具有与正晶相反的光学相反特性的物质，即具有与负晶体的双折射相当的双折射的物质来补偿由向列型液晶分子的双折射引起的相位差。

9. 发明申请

US20050088950A1 Optical pickup and disk drive apparatus 失效
标题翻译：光学拾取和磁盘驱动装置
公开(公告)号：US20050088950A1
公开(公告)日：2005-04-28
申请号：US10943858
申请日：2004-09-20
申请人： Takeshi Tanimoto
发明人： Takeshi Tanimoto
IPC分类号： G11B7/00 , G11B7/09 , G11B7/095 , G11B7/135
CPC分类号： G11B7/1353 , G11B7/0903 , G11B7/0953 , G11B2007/0006
摘要： In an optical pickup for irradiating a laser beam emitted from a photoemission element on a disk-like recording medium through an objective lens, there is provided a diffraction element including a first region for splitting the laser beam emitted from the photoemission element into a main beam and a pair of first sub-beams and a second region for splitting the laser into a main beam and a pair of second sub-beams, wherein a following relation hold or approximately hold: (2n−1)×P/2, where D is a distance between a spot center of the first sub-beam and a spot center of the second sub-beam, the spots being formed on a recording surface of the disk-like recording medium spaced in a substantially radial direction of the disk-like recording medium, n is a natural number, and P is a track pitch of the disk-like recording medium.
摘要翻译：在通过物镜将从光电子发射元件发射的激光束照射在盘状记录介质上的光学拾取器中，提供了一种衍射元件，其包括：第一区域，用于将从光电子发射元件发射的激光束分裂成主光束以及一对第一子光束和第二区域，用于将激光分割为主光束和一对第二子光束，其中以下关系成立或保持：（2n-1）×P / 2，其中D为所述第一子光束的光斑中心与所述第二子光束的光点中心之间的距离，所述光斑形成在所述盘状记录介质的记录表面上，所述记录表面沿盘状记录的大致径向方向间隔开介质，n是自然数，P是盘状记录介质的轨道间距。

10. 发明授权

US07444114B2 Image forming apparatus and image forming method 失效
标题翻译：图像形成装置及图像形成方法
公开(公告)号：US07444114B2
公开(公告)日：2008-10-28
申请号：US11209855
申请日：2005-08-24
申请人： Takeshi Tanimoto
发明人： Takeshi Tanimoto
IPC分类号： G03G15/00
CPC分类号： G03G15/6567 , G03G2215/00565
摘要： An image forming apparatus that conveys a long belt-like recording sheet on a conveyance path and forms an image on the recording sheet when the recording sheet passes through an image forming section, the image forming apparatus comprising: a recording medium drive component that is disposed downstream of the image forming section in a conveyance direction on the conveyance path and conveys the recording medium; a tension imparting component that is disposed upstream of the image forming section in the conveyance direction on the conveyance path and imparts tension to the recording medium; and a control unit which, when a printing operation for forming an image is started, drives the tension imparting component to impart tension to the recording medium between the recording medium drive component and the tension imparting component, and starts the recording medium conveyance operation.
摘要翻译：一种图像形成装置，其在记录纸通过图像形成部时将长带状记录纸传送到传送路径上并在记录纸上形成图像，所述图像形成装置包括：记录介质驱动部件，其被配置在输送路径上的传送方向上的图像形成部分的下游，并传送记录介质; 张力赋予部件，其在所述输送路径的输送方向上配置在所述图像形成部的上游，并且向所述记录介质施加张力; 以及控制单元，当开始形成图像的打印操作时，驱动张力赋予分量，以在记录介质驱动部件和张力赋予部件之间向记录介质施加张力，并开始记录介质输送操作。

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