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    • 6. 发明申请
    • Silica Composite Capsules Obtained By Blending Water-Soluble Silane Derivative, Composition Containg The Same, And Transparent Gel-Form Composition
    • 通过混合水溶性硅烷衍生物获得的二氧化硅复合胶囊,含有它的组合物和透明的凝胶形式组合物
    • US20100016200A1
    • 2010-01-21
    • US12440614
    • 2007-09-11
    • Yuko NagareKei WatanabeKazutami SakamotoShun TakahashiTeruhiko Hineno
    • Yuko NagareKei WatanabeKazutami SakamotoShun TakahashiTeruhiko Hineno
    • A61K8/06
    • A61Q19/10A61K8/0291A61K8/0295A61K8/042A61K8/11A61K8/25A61K8/585A61K2800/262A61K2800/412A61Q1/02
    • The present invention provides new silica composite capsules that can be easily prepared, a composition containing the silica composite capsules, and a transparent gel-form composition excellent in appearance transparency and texture in use, and in particular, a transparent gel-form composition with improved cleansing properties when used as a cleanser. Micelle/silica composite capsules can easily be obtained, in an aqueous system, by mixing a material capable of forming micelles in water and a water-soluble silane derivative having a specific structure in aqueous solution. In addition, emulsion/silica composite capsules wherein the periphery of emulsion particles in the inner phase is coated with silica, can easily be obtained by mixing a surfactant, water, an oil, and a water-soluble silane derivative having a specific structure. Moreover, a transparent gel-form composition showing excellent appearance transparency, the texture in use and cleansing properties, can be obtained by blending a water-soluble silane derivative having a specific structure into the formulation that contains a surfactant, an oil and water, and capable of taking a surfactant association structure with aqueous continuous phase or both of aqueous continuous phase and oil continuous phase in the formulation.
    • 本发明提供了可以容易地制备的新的二氧化硅复合胶囊,含有二氧化硅复合胶囊的组合物,以及外观透明性和使用质地优异的透明凝胶状组合物,特别是具有改进的透明凝胶状组合物 用作清洁剂时的清洁性能。 通过将能够在水中形成胶束的材料和在水溶液中具有特定结构的水溶性硅烷衍生物混合,可以在水性体系中容易地获得胶束/二氧化硅复合胶囊。 此外,通过混合表面活性剂,水,油和具有特定结构的水溶性硅烷衍生物,可以容易地得到内层的乳液粒子的周围用二氧化硅涂布的乳液/二氧化硅复合胶囊。 此外,通过将具有特定结构的水溶性硅烷衍生物掺入含有表面活性剂,油和水的配方中,可以获得表现出优异的外观透明度,使用质地和清洁性能的透明凝胶状组合物,以及 能够在制剂中具有含水连续相或水相连续相和油连续相的表面活性剂缔合结构。
    • 7. 发明授权
    • Silica composite capsules obtained by blending water-soluble silane derivative, composition containing the same, and transparent gel-form composition
    • 通过混合水溶性硅烷衍生物,含有它们的组合物和透明凝胶状组合物获得的二氧化硅复合胶囊
    • US08030267B2
    • 2011-10-04
    • US12440614
    • 2007-09-11
    • Yuko NagareKei WatanabeKazutami SakamotoShun TakahashiTeruhiko Hineno
    • Yuko NagareKei WatanabeKazutami SakamotoShun TakahashiTeruhiko Hineno
    • C11D9/36C11D3/44
    • A61Q19/10A61K8/0291A61K8/0295A61K8/042A61K8/11A61K8/25A61K8/585A61K2800/262A61K2800/412A61Q1/02
    • The present invention provides new silica composite capsules that can be easily prepared, a composition containing the silica composite capsules, and a transparent gel-form composition excellent in appearance transparency and texture in use, and in particular, a transparent gel-form composition with improved cleansing properties when used as a cleanser. Micelle/silica composite capsules can easily be obtained, in an aqueous system, by mixing a material capable of forming micelles in water and a water-soluble silane derivative having a specific structure in aqueous solution. In addition, emulsion/silica composite capsules wherein the periphery of emulsion particles in the inner phase is coated with silica, can easily be obtained by mixing a surfactant, water, an oil, and a water-soluble silane derivative having a specific structure. Moreover, a transparent gel-form composition showing excellent appearance transparency, the texture in use and cleansing properties, can be obtained by blending a water-soluble silane derivative having a specific structure into the formulation that contains a surfactant, an oil and water, and capable of taking a surfactant association structure with aqueous continuous phase or both of aqueous continuous phase and oil continuous phase in the formulation.
    • 本发明提供了可以容易地制备的新的二氧化硅复合胶囊,含有二氧化硅复合胶囊的组合物,以及外观透明性和使用质地优异的透明凝胶状组合物,特别是具有改进的透明凝胶状组合物 用作清洁剂时的清洁性能。 通过将能够在水中形成胶束的材料和在水溶液中具有特定结构的水溶性硅烷衍生物混合,可以在水性体系中容易地获得胶束/二氧化硅复合胶囊。 此外,通过混合表面活性剂,水,油和具有特定结构的水溶性硅烷衍生物,可以容易地得到内层的乳液粒子的周围用二氧化硅涂布的乳液/二氧化硅复合胶囊。 此外,通过将具有特定结构的水溶性硅烷衍生物掺入含有表面活性剂,油和水的配方中,可以获得表现出优异的外观透明度,使用质地和清洁性能的透明凝胶状组合物,以及 能够在制剂中具有含水连续相或水相连续相和油连续相的表面活性剂缔合结构。
    • 8. 发明申请
    • Solubilized Composition
    • 溶解组合物
    • US20120027712A1
    • 2012-02-02
    • US13257352
    • 2010-03-09
    • Takashi TeshigawaraHidefumi ArakiKei Watanabe
    • Takashi TeshigawaraHidefumi ArakiKei Watanabe
    • A61K8/58A61Q5/00A61Q7/00A61Q19/00
    • C08L71/02A61K8/39A61K8/585A61K8/86A61K8/891A61Q19/00C08K5/5419C08K5/549C08L83/04
    • This invention provides a solubilized composition in which a cyclic or straight silicone oil is solubilized in a large amount and stably. The solubilized composition is characterized by comprising (a) a polyoxyethylene alkyl ether type nonionic surfactant represented by the following formula (I): R1—O—(CH2CH2O)a—H  (I) wherein R1 represents a branched chain alkyl group having 8 to 18 carbon atoms; a represents an integer satisfying 3≦a≦20, (b) one or more silicone(s) selected from a cyclic silicone represented by the following formula (II) and a short chain straight silicone represented by the following formula (III): [(CH3)HSi—O—]m  (II) (CH3)3Si—O—[Si(CH3)2O]nSi(CH3)3  (III) wherein m represents an integer satisfying 3≦m≦7; and n represents an integer satisfying 0≦n≦7, and (c) water.
    • 本发明提供一种溶解组合物,其中环状或直链硅油大量且稳定地溶解。 该溶解组合物的特征在于:(a)由下式(I)表示的聚氧乙烯烷基醚型非离子表面活性剂:R1-O-(CH2CH2O)a-H(Ⅰ),其中R1表示支链烷基, 18个碳原子; a表示满足3&nlE的整数; a≦̸ 20,(b)选自由下式(II)表示的环状硅氧烷中的一种或多种硅酮和由下式(III)表示的短链直链硅氧烷:[ (CH3)HSi-O-] m(II)(CH3)3Si-O- [Si(CH3)2O] nSi(CH3)3(Ⅲ)其中m表示满足3&nlE的整数; m& n表示满足0&nlE的整数; n≦̸ 7,(c)水。
    • 9. 发明申请
    • Solubilized Composition
    • 溶解组合物
    • US20120010169A1
    • 2012-01-12
    • US13257691
    • 2010-03-09
    • Takashi TeshigawaraKei WatanabeHidefumi Araki
    • Takashi TeshigawaraKei WatanabeHidefumi Araki
    • A61K8/58A61Q19/00
    • C08L71/02A61K8/04A61K8/39A61K8/86A61K8/891A61Q19/00C08G77/14C08K5/5419C08L83/06C08L83/04
    • This invention provides a solubilized composition in which a carboxy-modified silicone is solubilized in a large amount and stably. The solubilized composition is characterized by consisting of (a) one or more nonionic surfactant(s), having a weighted average of the HLB value of 10 to 15, selected from polyoxyethylene alkyl ether type nonionic surfactant represented by the following formula (I) or (II): wherein R1 represents a branched chain alkyl group having 8 to 18 carbon atoms; a represents an integer satisfying 3≦a≦40; any one or more of R2, R3 and R4 are each a branched chain alkyl group having 8 to 18 carbon atoms and the other(s) is a hydroxy group; and b, c and d each represent an integer satisfying 3≦b+c+d≦40,(b) a carboxy-modified silicone, and(c) water, andwherein the amount of (b) the carboxy-modified silicone is three times or less the weight of (a) the nonionic surfactant(s).
    • 本发明提供一种溶解组合物,其中羧基改性的硅氧烷大量且稳定地溶解。 该溶解组合物的特征在于:(a)一种或多种HLB值加权平均值为10〜15的非离子表面活性剂,其选自由下式(I)表示的聚氧乙烯烷基醚型非离子表面活性剂或 (II)表示:其中R1表示碳原子数为8〜18的支链烷基; a表示满足3&nlE的整数; a≦̸ 40; R 2,R 3和R 4中的任何一个或多个各自为具有8至18个碳原子的支链烷基,而另一个为羟基; b,c和d分别表示满足3≦̸ b + c + d≦̸ 40,(b)羧基改性硅氧烷和(c)水的整数,其中(b)羧基改性硅氧烷的量为 (a)非离子表面活性剂的重量的三倍或更少。