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1. 发明专利

JP2005089301A Therapeutic agent for bovine digestive system disease 有权
标题翻译：牛病毒系统疾病治疗药物
公开(公告)号：JP2005089301A
公开(公告)日：2005-04-07
申请号：JP2003320517
申请日：2003-09-12
申请人： Bio Vet Inc , Hayashibara Biochem Lab Inc , バイオベット株式会社 , 株式会社林原生物化学研究所
发明人： TAMURA TAKETOSHI , TAKAHASHI KATSUNARI , MIWA NAOKATSU
IPC分类号： A61K38/21 , A61P1/00 , A61P1/12 , A61P31/14 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To obtain a therapeutic agent for bovine digestive system diseases and to provide a method for treating bovine digestive diseases by using the therapeutic agent. SOLUTION: This therapeutic agent for digestive system diseases comprises an interferon as an active ingredient. The method for treating the bovine digestive diseases comprises using the bovine digestive system diseases. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：获得牛消化系统疾病的治疗剂，并提供通过使用治疗剂治疗牛消化疾病的方法。解决方案：用于消化系统疾病的治疗剂包括干扰素作为活性成分。用于治疗牛消化系统疾病的方法包括使用牛消化系统疾病。版权所有（C）2005，JPO＆NCIPI

2. 发明专利

JP2013090574A Peptide vaccine 审中-公开
标题翻译： PEPTIDE VACCINE
公开(公告)号：JP2013090574A
公开(公告)日：2013-05-16
申请号：JP2010010953
申请日：2010-01-21
申请人： Daiichi Sankyo Co Ltd , 第一三共株式会社 , Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所
发明人： KANAZAWA YOSHIHITO , MIWA NAOKATSU , YANO AKIRA
IPC分类号： C12N15/09 , A61K39/00 , A61P25/28 , C07K14/00
CPC分类号： C07K14/4711 , A61K39/00 , A61K39/0007 , A61K2039/55566 , A61K2039/6037 , C07K2319/55
摘要： PROBLEM TO BE SOLVED: To provide a peptide which is excellent in immunogenicity, has higher antibody production-inducing ability, and can reinforce production of an objective antibody, even when additionally administered.SOLUTION: The peptide comprises an amino acid sequence of cell-binding motif of a cell adhesion molecule, an amino acid sequence (T) containing an amino acid sequence of a cell T epitope in which immunological memory is established, an amino acid sequence (B) containing an amino acid sequences of one or more specific cell B epitopes of an antigen, and amino acid sequences of linker peptides arranged to link the T and the B between the T and the B, wherein the amino acid sequences of the linker peptides are GKK or VVKK. A composition containing the peptide as an active ingredient is disclosed.
摘要翻译：要解决的问题：为了提供免疫原性优异的肽，具有更高的抗体产生诱导能力，并且即使当另外施用时也可以加强目标抗体的产生。解决方案：肽包含细胞粘附分子的细胞结合基序的氨基酸序列，含有其中建立免疫记忆的细胞T表位的氨基酸序列的氨基酸序列（T），氨基酸包含抗原的一个或多个特异性细胞B表位的氨基酸序列的序列（B）和连接T和B之间的T和B之间的连接肽的氨基酸序列，其中，接头肽是GKK或VVKK。公开了含有肽作为活性成分的组合物。版权所有（C）2013，JPO＆INPIT

3. 发明专利

JP2005281253A Skin cosmetic 有权
标题翻译：皮肤化妆品
公开(公告)号：JP2005281253A
公开(公告)日：2005-10-13
申请号：JP2004101061
申请日：2004-03-30
申请人： Hayashibara Biochem Lab Inc , Nof Corp , 日本油脂株式会社 , 株式会社林原生物化学研究所
发明人： ISHIDA MISAKI , MIWA NAOKATSU
IPC分类号： A61K8/72 , A61K8/00 , A61K8/96 , A61K8/97 , A61Q19/00 , A61K7/00 , A61K7/48
摘要： PROBLEM TO BE SOLVED: To provide a skin cosmetic which feels light in use to quickly agree with the skin, is not sticky even after use, excels in persistence of humectant effects, ameliorating effects on skin roughening, suppressing effects on wrinkles, furthermore imparts firmness to the skin, and also excels in stability with time.
SOLUTION: The skin cosmetic comprises (a) 0.005-10 mass% polymer containing a 2-(meth)acryloyloxyethylphosphorylcholine represented by formula (I)(wherein R
1 is hydrogen or a methyl group; R
2 , R
3 , and R
4 are each a 1-8C alkyl group; and n is an integer of 2-4) and an alkyl (meth)acrylate at a constituting ratio of 100/0 to 10/90 in an amount of 60-100 mass% and (b) 0.0001-5 mass% extract in terms of a dry residue obtained by extracting Polygonum tinctorium Lour.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：为了提供使用感觉快速与皮肤相符的皮肤化妆品，即使使用后也不粘，优异的保湿效果的持久性，改善对皮肤粗糙化的作用，抑制对皱纹的影响，进一步赋予皮肤坚实性，并且随着时间的推移稳定。皮肤化妆品包含（a）含有式（I）所示的2-（甲基）丙烯酰氧基乙基磷酰胆碱（其中R 1 为氢或甲基）的0.005-10质量％聚合物; R 2 ，R 3 和R 4 各自为1-8C烷基; n为2-4的整数）和（甲基）丙烯酸烷基酯，其组成比为100/0至10/90，其量为60-100质量％，和（b）0.0001-5质量％的提取物，以通过提取枸橼酸钾获得的干燥残余物。版权所有（C）2006，JPO＆NCIPI

4. 发明专利

JP2010189448A Therapeutic agent for bovine digestive disorder 审中-公开
标题翻译：牛血清病毒治疗药物
公开(公告)号：JP2010189448A
公开(公告)日：2010-09-02
申请号：JP2010132479
申请日：2010-06-09
申请人： Bio Vet Inc , Hayashibara Biochem Lab Inc , バイオベット株式会社 , 株式会社林原生物化学研究所
发明人： TAMURA TAKETOSHI , TAKAHASHI KATSUNARI , MIWA NAOKATSU
IPC分类号： A61K38/21 , A61P31/12
摘要： PROBLEM TO BE SOLVED: To provide a therapeutic agent for bovine digestive disorder, and a method for treating bovine digestive disorder using the same. SOLUTION: There is provided a therapeutic agent for digestive disorder containing interferon as an active ingredient. The method for treating bovine digestive disorder using the therapeutic agent is also provided. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：待解决的问题：提供牛消化系统疾病的治疗剂，以及使用其治疗牛消化系统疾病的方法。解决方案：提供含有干扰素作为活性成分的消化紊乱的治疗剂。还提供了使用治疗剂治疗牛消化系统疾病的方法。版权所有（C）2010，JPO＆INPIT

5. 发明专利

JP2008056631A Sulfated cyclic tetrasaccharide or salt thereof 有权
标题翻译：硫化循环四氯化碳或其盐
公开(公告)号：JP2008056631A
公开(公告)日：2008-03-13
申请号：JP2006237849
申请日：2006-09-01
申请人： Chisso Corp , Hayashibara Biochem Lab Inc , チッソ株式会社 , 株式会社林原生物化学研究所
发明人： SATO IKUO , UCHINO MASAZUMI , MIWA NAOKATSU
IPC分类号： C07H11/00 , A23L1/09 , A23L1/30 , A61K8/60 , A61K31/7024 , A61P7/02 , A61P31/12 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide a sulfated cyclic tetrasaccharide effectively utilizable for a food, a cosmetic, a medical therapeutic agent, etc., or a salt thereof. SOLUTION: The compound is obtained by sulfating hydroxy groups of a cyclic tetrasaccharide in which 4 molecules of glucose form a cyclic structure through an α-1,3-glycosyl bond and an α-1,6-glycosyl bond. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供可有效地用于食品，化妆品，医疗治疗剂等的硫酸化环状四糖或其盐。解决方案：通过使4分子葡萄糖通过α-1,3-糖基键和α-1,6-糖基键形成环状结构的环状四糖的羟基硫酸化获得化合物。版权所有（C）2008，JPO＆INPIT

6. 发明专利

JP2012140468A Peritoneal dialysis fluid 有权
标题翻译： PERITONEAL DIALYSIS FLUID
公开(公告)号：JP2012140468A
公开(公告)日：2012-07-26
申请号：JP2012093372
申请日：2012-03-30
申请人： Hayashibara Biochem Lab Inc , 株式会社林原生物化学研究所
发明人： OTA HITOMI , HANATANI TOSHIHARU , FUKUDA SHIGEHARU , MIWA NAOKATSU , MIYAKE TOSHIO
IPC分类号： A61K31/702 , A61K31/7042 , A61P7/08
CPC分类号： A61K31/716 , A61K31/702 , A61K31/7048 , A61M1/287 , A61K2300/00
摘要： PROBLEM TO BE SOLVED: To provide a peritoneal dialysis fluid, which is excellent in a water removal performance, has high biocompatibility, and is excellent in storage stability.SOLUTION: The peritoneal dialysis fluid contains one or more substances selected from cyclonigerosyl nigerose, cyclomaltosyl maltose and L-ascorbic acid 2-glucoside.
摘要翻译：要解决的问题：提供一种除水性能优异的腹膜透析液，具有高的生物相容性，并且储存稳定性优异。解决方案：腹膜透析液含有一种或多种选自旋风黑素黑素，环麦芽糖基麦芽糖和L-抗坏血酸2-葡萄糖苷的物质。版权所有（C）2012，JPO＆INPIT

7. 发明专利

JP2005089356A Isomaltooligosaccharide-containing cosmetic composition 审中-公开
标题翻译：含异麦芽糖含量化妆品组合物
公开(公告)号：JP2005089356A
公开(公告)日：2005-04-07
申请号：JP2003323805
申请日：2003-09-17
申请人： Hayashibara Biochem Lab Inc , Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社 , 株式会社林原生物化学研究所
发明人： TANABE FUJIMI , MIWA NAOKATSU , YAMADA KIOMI , HASEBE KOHEI
IPC分类号： A61K8/60 , A61K8/00 , A61K8/02 , A61K8/03 , A61K8/06 , A61K8/30 , A61K8/34 , A61K8/73 , A61Q1/00 , A61Q1/12 , A61Q5/02 , A61K7/00 , A61K7/075
摘要： PROBLEM TO BE SOLVED: To obtain a polyhydric alcohol-containing cosmetic composition that is usable without sensing an unpleasant feeling of greasiness, relieves an unpleasant creaky feeling of the hair, is safe, and has excellent moisture retaining effect on the skin and the hair and a comfortable sense of use. SOLUTION: The polyhydric alcohol-containing cosmetic composition contains an isomaltooligosaccharide. Consequently, the cosmetic composition is usable without feeling the unpleasant feeling of greasiness and a creaky feeling of the hair caused by a polyhydric alcohol in spite of containing the polyhydric alcohol and yet is safe and has excellent moisture retaining effect and a comfortable sense of use. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题为了获得可以在不感觉到不愉快的油腻感的情况下使用的多元醇的化妆品组合物，缓解头发的令人不快的吱吱作响的感觉，是安全的，并且对皮肤具有优异的保湿效果，头发和舒适的使用感。解决方案：含多元醇的化妆品组合物含有异麦芽低聚糖。因此，即使含有多元醇，也可以使用化妆品组合物，而不会感觉到由多元醇引起的毛发的令人不快的感觉和头发的吱吱嘎吱的感觉，而且是安全的并且具有优异的保湿效果和舒适的使用感。版权所有（C）2005，JPO＆NCIPI

8. 发明专利

JP2005089355A Isomaltooligosaccharide-containing ameliorant for indigenous skin bacterial flora 审中-公开
标题翻译：含有土霉素的含异烟肼的土壤细菌
公开(公告)号：JP2005089355A
公开(公告)日：2005-04-07
申请号：JP2003323804
申请日：2003-09-17
申请人： Hayashibara Biochem Lab Inc , Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社 , 株式会社林原生物化学研究所
发明人： TANABE FUJIMI , MIWA NAOKATSU , YAMADA KIOMI , HASEBE KOHEI
IPC分类号： A61K8/00 , A61K8/30 , A61K8/60 , A61P17/00 , A61Q1/00 , A61Q1/12 , A61Q5/00 , A61Q5/02 , A61Q19/00 , A61K7/48 , A61K7/00
摘要： PROBLEM TO BE SOLVED: To develop an ameliorant for indigenous skin bacterial flora having adjusting action on the balance of indigenous skin bacterial flora and to obtain a cosmetic composition that prevents, alleviates or ameliorates an adverse effect on the skin and a scalp and has effect of keeping the skin and a scalp healthily. SOLUTION: The ameliorant for indigenous skin bacterial flora comprises an isomaltooligosaccharide and/or a sugar alcohol obtained by reducing an isomaltooligosaccharide. The cosmetic composition comprises them. The ameliorant for indigenous skin bacterial flora and the cosmetic composition adjust the balance of indigenous skin bacterial flora, prevent, alleviate or ameliorate the adverse effect on the skin and the scalp and improve an immune barrier function on the skin. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：开发用于土着皮肤细菌菌群的改良剂，其具有对本地皮肤细菌菌群平衡的调节作用，并获得防止，减轻或改善对皮肤和头皮的不利影响的化妆品组合物，具有保持皮肤和头皮健康的作用。解决方案：本土皮肤细菌菌群的改良剂包括通过还原异麦芽低聚糖获得的异麦芽低聚糖和/或糖醇。化妆品组合物包括它们。土着皮肤细菌菌群的改善剂和化妆品组合物调节土着皮肤细菌菌群的平衡，预防，减轻或改善对皮肤和头皮的不良影响，并改善皮肤的免疫屏障功能。版权所有（C）2005，JPO＆NCIPI

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