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1. 发明申请

US20070239245A1 CONDUCTIVE POLYMERIC COATING WITH OPTIONAL BIOBENEFICIAL TOPCOAT FOR A MEDICAL LEAD 失效
标题翻译：导电聚合物涂层与医疗领域的可选生物辅助
公开(公告)号：US20070239245A1
公开(公告)日：2007-10-11
申请号：US11277858
申请日：2006-03-29
申请人： Harshad Borgaonkar , Piotr Waszczuk , Daniel Cooke , Xiangchun Jiang
发明人： Harshad Borgaonkar , Piotr Waszczuk , Daniel Cooke , Xiangchun Jiang
IPC分类号： A61N1/00
CPC分类号： A61N1/0565 , A61N1/05 , A61N1/0568
摘要： A cardiac lead comprising a lead body extending from a proximal end portion to a distal end portion; a cardiac electrode disposed along the lead body; and a coating associated with at least a portion of the electrode, wherein the coating comprises a conductive polymer.
摘要翻译：一种心脏引线，包括从近端部分延伸到远端部分的引线体; 沿所述引线体设置的心电极; 以及与所述电极的至少一部分相关联的涂层，其中所述涂层包含导电聚合物。

2. 发明授权

US07881808B2 Conductive polymeric coating with optional biobeneficial topcoat for a medical lead 失效
标题翻译：导电聚合物涂层，其具有用于医疗引线的任选的生物利用面漆
公开(公告)号：US07881808B2
公开(公告)日：2011-02-01
申请号：US11277858
申请日：2006-03-29
申请人： Harshad Borgaonkar , Piotr Waszczuk , Daniel J. Cooke , Xiangchun Jiang
发明人： Harshad Borgaonkar , Piotr Waszczuk , Daniel J. Cooke , Xiangchun Jiang
IPC分类号： A61N1/00
CPC分类号： A61N1/0565 , A61N1/05 , A61N1/0568
摘要： A cardiac lead comprising a lead body extending from a proximal end portion to a distal end portion; a cardiac electrode disposed along the lead body; and a coating associated with at least a portion of the electrode, the coating comprises a conductive polymer.
摘要翻译：一种心脏引线，包括从近端部分延伸到远端部分的引线体; 沿所述引线体设置的心电极; 以及与所述电极的至少一部分相关联的涂层，所述涂层包含导电聚合物。

3. 发明申请

US20110087317A1 CONDUCTIVE POLYMERIC COATING WITH OPTIONAL BIOBENEFICIAL TOPCOAT FOR A MEDICAL LEAD 审中-公开
标题翻译：导电聚合物涂层与医疗领域的可选生物辅助
公开(公告)号：US20110087317A1
公开(公告)日：2011-04-14
申请号：US12955342
申请日：2010-11-29
申请人： Harshad Borgaonkar , Piotr Waszczuk , Daniel J. Cooke , Xiangchun Jiang
发明人： Harshad Borgaonkar , Piotr Waszczuk , Daniel J. Cooke , Xiangchun Jiang
IPC分类号： A61N1/05
CPC分类号： A61N1/0565 , A61N1/05 , A61N1/0568
摘要： A cardiac lead comprising a lead body extending from a proximal end portion to a distal end portion; a cardiac electrode disposed along the lead body; and a coating associated with at least a portion of the electrode, wherein the coating comprises a conductive polymer.
摘要翻译：一种心脏引线，包括从近端部分延伸到远端部分的引线体; 沿所述引线体设置的心电极; 以及与所述电极的至少一部分相关联的涂层，其中所述涂层包含导电聚合物。

4. 发明申请

US20070255378A1 LEAD WITH FIBROUS MATRIX COATING AND METHODS RELATED THERETO 有权
标题翻译：引导与纤维基质涂层和方法相关
公开(公告)号：US20070255378A1
公开(公告)日：2007-11-01
申请号：US11381018
申请日：2006-05-01
申请人： Jeannette Polkinghorne , Xiangchun Jiang , Daniel Cooke
发明人： Jeannette Polkinghorne , Xiangchun Jiang , Daniel Cooke
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/0568 , A61N2001/0585 , D01D5/0084 , Y10S977/904 , Y10S977/931
摘要： A lead includes a lead body extending from a lead proximal end portion to a lead distal end portion and having an intermediate portion therebetween, one or more tissue sensing/stimulation electrodes disposed along the lead body, one or more terminal connections disposed along the lead proximal end portion. The lead further includes one or more conductors contained within the lead body extending between the tissue sensing/stimulation electrodes and the terminal connections, and a fibrous matrix coating is disposed onto at least a portion of the lead body and/or sensing/stimulation electrodes.
摘要翻译：引线包括从引线近端部分延伸到引线远端部分并且在其间具有中间部分的引线体，沿着引线主体设置的一个或多个组织感测/刺激电极，沿着引线近端设置的一个或多个端子连接端部。引线还包括一个或多个导体，其包含在组织感测/刺激电极和端子连接之间延伸的引线体内，并且纤维基质涂层设置在引线体和/或感测/刺激电极的至少一部分上。

5. 发明申请

US20080202940A1 Electrodes With Increased Surface Area And Methods of Making 审中-公开
标题翻译：电极表面积增加和制造方法
公开(公告)号：US20080202940A1
公开(公告)日：2008-08-28
申请号：US11677905
申请日：2007-02-22
申请人： Xiangchun Jiang , Ronald W. Heil , Daniel J. Cooke
发明人： Xiangchun Jiang , Ronald W. Heil , Daniel J. Cooke
IPC分类号： B23H3/06
CPC分类号： A61N1/056 , C25F3/02
摘要： Disclosed herein, among other things, are high surface area electrodes and methods of making the same. In an embodiment, the invention includes a method of increasing the surface area of an electrode of an implantable medical device including immersing the electrode in an electrolyte solution and oxidatively removing material from the surface of the electrode. In an embodiment, the invention includes a method of increasing the surface area of an electrode of an implantable medical device including immersing the electrode in an electrolyte solution and applying an oscillating electrical potential. In an embodiment, the invention includes a method of manufacturing an implantable stimulation lead including welding an electrode to a conductor and increasing the surface area of the electrode by oxidatively removing a portion of the electrode surface. Other aspects and embodiments are provided herein.
摘要翻译：这里公开的是高表面积电极及其制造方法。在一个实施方案中，本发明包括增加可植入医疗装置的电极的表面积的方法，包括将电极浸入电解质溶液中并从电极的表面氧化去除材料。在一个实施例中，本发明包括增加可植入医疗装置的电极的表面积的方法，包括将电极浸入电解质溶液中并施加振荡电位。在一个实施例中，本发明包括一种制造可植入刺激引线的方法，包括将电极焊接到导体，并通过氧化去除电极表面的一部分来增加电极的表面积。本文提供了其它方面和实施例。

6. 发明授权

US08311606B2 Conductive polymer patterned electrode for pacing 有权
标题翻译：用于起搏的导电聚合物图案电极
公开(公告)号：US08311606B2
公开(公告)日：2012-11-13
申请号：US11533644
申请日：2006-09-20
申请人： Xiangchun Jiang , Kevin J. Ely , Jeannette C. Polkinghorne
发明人： Xiangchun Jiang , Kevin J. Ely , Jeannette C. Polkinghorne
IPC分类号： A61B5/04
CPC分类号： A61N1/056 , A61N1/0568
摘要： The present invention is an apparatus and method for making a polymer patterned electrode for cardiac pacing and sensing. The electrode surface includes a polymer overlayed on an electrode. The polymer layer is patterned to form an electrode surface consisting of a polymer and a conductive metal surface. The electrode can be made of a high or low impedance electrode by changing the conductivity of the polymer. Furthermore, the electrode surface texture can be optimized with a micro pattern that may enhance the biocompatibility. The polymer may be conductive or insulative.
摘要翻译：本发明是用于制造用于心脏起搏和感测的聚合物图案化电极的装置和方法。电极表面包括覆盖在电极上的聚合物。将聚合物层图案化以形成由聚合物和导电金属表面组成的电极表面。通过改变聚合物的导电性，电极可以由高阻抗或低阻抗电极制成。此外，电极表面纹理可以用可以增强生物相容性的微观图案来优化。聚合物可以是导电的或绝缘的。

7. 发明授权

US07689291B2 Lead with fibrous matrix coating and methods related thereto 有权
标题翻译：带有纤维基质涂层及其相关方法
公开(公告)号：US07689291B2
公开(公告)日：2010-03-30
申请号：US11381018
申请日：2006-05-01
申请人： Jeannette C. Polkinghorne , Xiangchun Jiang , Daniel J. Cooke
发明人： Jeannette C. Polkinghorne , Xiangchun Jiang , Daniel J. Cooke
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/0568 , A61N2001/0585 , D01D5/0084 , Y10S977/904 , Y10S977/931
摘要： A lead includes a lead body extending from a lead proximal end portion to a lead distal end portion and having an intermediate portion therebetween, one or more tissue sensing/stimulation electrodes disposed along the lead body, one or more terminal connections disposed along the lead proximal end portion. The lead further includes one or more conductors contained within the lead body extending between the tissue sensing/stimulation electrodes and the terminal connections, and a fibrous matrix coating is disposed onto at least a portion of the lead body and/or sensing/stimulation electrodes.
摘要翻译：引线包括从引线近端部分延伸到引线远端部分并且在其间具有中间部分的引线体，沿着引线主体设置的一个或多个组织感测/刺激电极，沿着引线近端设置的一个或多个端子连接端部。引线还包括一个或多个导体，其包含在组织感测/刺激电极和端子连接之间延伸的引线体内，并且纤维基质涂层设置在引线体和/或感测/刺激电极的至少一部分上。

8. 发明申请

US20080071338A1 CONDUCTIVE POLYMER PATTERNED ELECTRODE FOR PACING 有权
标题翻译：导电聚合物图案电极
公开(公告)号：US20080071338A1
公开(公告)日：2008-03-20
申请号：US11533644
申请日：2006-09-20
申请人： Xiangchun Jiang , Kevin J. Ely , Jeannette C. Polkinghorne
发明人： Xiangchun Jiang , Kevin J. Ely , Jeannette C. Polkinghorne
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0568
摘要： The present invention is an apparatus and method for making a polymer patterned electrode for cardiac pacing and sensing. The electrode surface includes a polymer overlayed on an electrode. The polymer layer is patterned to form an electrode surface consisting of a polymer and a conductive metal surface. The electrode can be made of a high or low impedance electrode by changing the conductivity of the polymer. Furthermore, the electrode surface texture can be optimized with a micro pattern that may enhance the biocompatibility. The polymer may be conductive or insulative.
摘要翻译：本发明是用于制造用于心脏起搏和感测的聚合物图案化电极的装置和方法。电极表面包括覆盖在电极上的聚合物。将聚合物层图案化以形成由聚合物和导电金属表面组成的电极表面。通过改变聚合物的导电性，电极可以由高阻抗或低阻抗电极制成。此外，电极表面纹理可以用可以增强生物相容性的微观图案来优化。聚合物可以是导电的或绝缘的。

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