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1. 发明申请

US20050025043A1 System and method for providing alternate routing in a network 有权
标题翻译：在网络中提供备用路由的系统和方法
公开(公告)号：US20050025043A1
公开(公告)日：2005-02-03
申请号：US10629517
申请日：2003-07-29
申请人： Harry Mussman , James O'Brien , Eric Sporel , Robert Israel , Michael Baj
发明人： Harry Mussman , James O'Brien , Eric Sporel , Robert Israel , Michael Baj
IPC分类号： H04L1/22 , H04L12/28 , H04L29/06 , H04M7/00 , H04Q3/66 , H04L12/26
CPC分类号： H04L65/1043 , H04L1/22 , H04L12/5692 , H04L29/06027 , H04L65/103 , H04L65/104 , H04L65/1069 , H04L65/80 , H04M7/0057 , H04Q3/66 , H04Q2213/13034 , H04Q2213/13138 , H04Q2213/13141 , H04Q2213/13167 , H04Q2213/13389
摘要： Methods and systems are described for performing alternate routing of communications in a network. The system initiates a communication from an origination endpoint in a packet-switched network, such as a VoIP network, to a destination endpoint, and determining, according to selection criteria, whether to route the communication to the destination endpoint using at least a second circuit-switched network, such as the PSTN.
摘要翻译：描述了用于在网络中执行通信的替代路由的方法和系统。该系统从诸如VoIP网络的分组交换网络中的发起端点发起到目的地端点的通信，以及根据选择标准确定是否使用至少第二电路将通信路由到目的地端点切换网络，如PSTN。

2. 发明申请

US20070165607A1 SYSTEM AND METHOD FOR PROVIDING ALTERNATE ROUTING IN A NETWORK 有权
标题翻译：在网络中提供替代路由的系统和方法
公开(公告)号：US20070165607A1
公开(公告)日：2007-07-19
申请号：US11693598
申请日：2007-03-29
申请人： Harry Mussman , James O'Brien , Eric Sporel , Robert Israel , Michael Baj
发明人： Harry Mussman , James O'Brien , Eric Sporel , Robert Israel , Michael Baj
IPC分类号： H04L12/66 , H04L12/56
CPC分类号： H04L65/1043 , H04L1/22 , H04L12/5692 , H04L29/06027 , H04L65/103 , H04L65/104 , H04L65/1069 , H04L65/80 , H04M7/0057 , H04Q3/66 , H04Q2213/13034 , H04Q2213/13138 , H04Q2213/13141 , H04Q2213/13167 , H04Q2213/13389
摘要： Methods and systems are described for performing alternate routing of communications in a network. The system initiates a communication from an origination endpoint in a packet-switched network, such as a VOIP network, to a destination endpoint, and determining, according to selection criteria, whether to route the communication to the destination endpoint using at least a second circuit-switched network, such as the PSTN.
摘要翻译：描述了用于在网络中执行通信的替代路由的方法和系统。系统发起从诸如VOIP网络的分组交换网络中的始发端点到目的地端点的通信，以及根据选择标准确定是否使用至少第二电路将通信路由到目的地端点切换网络，如PSTN。

3. 发明申请

US20080112327A1 ALTERNATE ROUTING OF VOICE COMMUNICATION IN A PACKET-BASED NETWORK 有权
标题翻译：基于分组网络的语音通信的替代路由
公开(公告)号：US20080112327A1
公开(公告)日：2008-05-15
申请号：US12017321
申请日：2008-01-21
申请人： Harry Mussman , John McCabe , David McGuigan , Robert Israel , Eric Sporel
发明人： Harry Mussman , John McCabe , David McGuigan , Robert Israel , Eric Sporel
IPC分类号： H04L12/56
CPC分类号： H04M7/006 , H04L29/06027 , H04L65/1009 , H04L65/103 , H04L65/104 , H04L65/1069 , H04M15/00
摘要： A method for performing alternate and therefore least cost routing in distributed H.323 Voice over IP (VoIP) networks is provided. With this method, the VoIP network consists of a hierarchy of gatekeeper (GK) functions to provide alternate routing, network element redundancy, and scalability. The alternate routing function is performed by a directory gatekeeper with route selection advancing from a first route to a second route by either of two conditions: (1) there are no resources available to terminate the call in the first zone; and (2) a lack of response to the directory GK request for such resources.
摘要翻译：提供了一种在分布式H.323 IP语音（VoIP）网络中执行交替且因此最低成本路由的方法。通过这种方法，VoIP网络由网守（GK）功能的层次结构组成，提供备用路由，网元冗余和可扩展性。替代路由功能由具有从第一路由前进到第二路由的路由选择的目录网守执行两个条件之一：（1）没有资源可用于终止第一区域中的呼叫; 和（2）对这种资源的目录GK请求的缺乏响应。

4. 发明申请

US20060144872A1 Device for the portioned dispensing of contained product, and method of use thereof 审中-公开
标题翻译：用于分批包装的产品的装置及其使用方法
公开(公告)号：US20060144872A1
公开(公告)日：2006-07-06
申请号：US11029057
申请日：2005-01-03
申请人： Robert Israel , Shyrah Maurer
发明人： Robert Israel , Shyrah Maurer
IPC分类号： G01F11/26
CPC分类号： G01F11/261
摘要： A consumer inserts a consumable product into a main storage area of the present device. A lid is secured to the top of the container. By tipping the container to the proper angle, product from main storage area is forced into holding barrier volume at the top of the container resulting in a specific amount of product to be held by the barrier. The container is then tipped upright and the measured product amount drops into the bottom of a measure compartment. The container is then inverted once more with the top of measure compartment now open, thereby allowing the measured product to be dispensed from the container, whereby the product from the main storage area is again forced into the holding barrier and process may be repeated.
摘要翻译：消费者将消耗品插入到本装置的主存储区域中。盖子固定在容器的顶部。通过将容器倾翻到适当的角度，从主存储区域的产品被迫保持在容器顶部的阻挡体积，导致特定量的产品被屏障保持。然后将容器倾斜直立，并且测量的产品量落入测量隔室的底部。然后将容器倒置一次，测量隔间的顶部现在打开，从而允许从容器中分配测量的产品，由此来自主存储区域的产品再次被迫进入保持屏障并且可以重复处理过程。

5. 发明申请

US20060205753A1 Use of methylnaltrexone and related compounds to treat post-operative gastrointestinal dysfunction 审中-公开
标题翻译：使用甲基纳曲酮和相关化合物治疗术后胃肠功能障碍
公开(公告)号：US20060205753A1
公开(公告)日：2006-09-14
申请号：US11336418
申请日：2006-01-20
申请人： Robert Israel
发明人： Robert Israel
IPC分类号： A61K31/485
CPC分类号： A61K31/485
摘要： Methods and compositions for treating post-surgical gastrointestinal dysfunction are provided. Methods include administering a quaternary derivative of noroxymorphone (e.g., methylnaltrexone) to a patient after a segmental colectomy is performed on the patient.
摘要翻译：提供了治疗手术后胃肠功能障碍的方法和组合物。方法包括在对患者进行节段性结肠切除术后向患者施用去甲吗啡酮（例如甲基纳曲酮）的季衍生物。

6. 发明申请

US20050004155A1 Use of methylnaltrexone to treat irritable bowel syndrome 审中-公开
标题翻译：使用甲基纳曲酮治疗肠易激综合征
公开(公告)号：US20050004155A1
公开(公告)日：2005-01-06
申请号：US10821813
申请日：2004-04-08
申请人： Thomas Boyd , Robert Israel , Suketu Sanghvi
发明人： Thomas Boyd , Robert Israel , Suketu Sanghvi
IPC分类号： A61K9/00 , A61K9/02 , A61K9/20 , A61K9/28 , A61K31/00 , A61K31/485 , A61K31/765 , A61K45/06 , A61P1/00
CPC分类号： A61K45/06 , A61K9/0031 , A61K9/02 , A61K9/2009 , A61K9/2013 , A61K9/2054 , A61K9/2846 , A61K9/2866 , A61K31/00 , A61K31/485 , A61K31/765 , A61K2300/00
摘要： Methods of treating irritable bowel syndrome with peripheral opioid antagonists, such as methylnaltrexone, are provided. Formulations comprising peripheral opioid antagonists, such as methylnaltrexone, and irritable bowel syndrome therapeutic agents are also provided.
摘要翻译：提供了与周围阿片样物质拮抗剂如甲基纳曲酮治疗肠易激综合征的方法。还提供了包含周围阿片样物质拮抗剂如甲基纳曲酮和肠易激综合征治疗剂的制剂。

7. 发明授权

US07346043B1 Allocation of channel capacity in multiservice networks 有权
标题翻译：多业务网络中信道容量的分配
公开(公告)号：US07346043B1
公开(公告)日：2008-03-18
申请号：US10158771
申请日：2002-05-30
申请人： Robert Olshansky , James D. O'Brien , Robert Israel , Harry Edward Mussman , David F. McGuigan
发明人： Robert Olshansky , James D. O'Brien , Robert Israel , Harry Edward Mussman , David F. McGuigan
IPC分类号： H04L12/66
CPC分类号： H04Q3/0045 , H04L41/0213 , H04L41/0253 , H04L41/0803 , H04L41/22 , H04L41/508 , H04Q2213/13034 , H04Q2213/13176 , H04Q2213/13196 , H04Q2213/13389
摘要： Methods are described which enable the operator of a network such as an Internet protocol (IP) network to allocate ingress and egress channel capacity for the use by different services or for use by different service providers. The methods can prevent a service provider or a service from overusing network capacity. The methods also enable the network operator to temporarily allocate unused capacity if demand for a service exceeds previously allocated capacity. Further a method is described whereby capacity on a Voice over Internet protocol (VoIP) network is sold to service providers with guarantees for the number of available channels, where the channel capacity guarantees could be global, or by any type of subdivision. In addition to having a committed channel capacity, the service provider could be allowed to exceed the committed capacity whenever excess capacity is available on the network.
摘要翻译：描述使得诸如因特网协议（IP）网络的网络的运营商能够分配不同服务使用或不同服务提供商使用的入口和出口信道容量的方法。这些方法可以防止服务提供商或服务过度使用网络容量。如果服务需求超过预先分配的容量，这些方法还使得网络运营商能够临时分配未使用的容量。此外，还描述了一种方法，其中在因特网协议（VoIP）网络上的容量被销售给服务提供商，其中保证可用信道的数量，其中信道容量保证可以是全局的，或者通过任何类型的细分。除了具有承诺的信道容量之外，当网络上的超量容量可用时，服务提供商可以被允许超过承诺的容量。

8. 发明授权

US07239629B1 Multiservice network 失效
标题翻译：多业务网络
公开(公告)号：US07239629B1
公开(公告)日：2007-07-03
申请号：US09452915
申请日：1999-12-01
申请人： Robert Olshansky , Robert Israel , Elliot Eichen
发明人： Robert Olshansky , Robert Israel , Elliot Eichen
IPC分类号： H04L12/66 , H04L12/28 , H04L12/56
CPC分类号： H04Q3/0045 , H04L41/0213 , H04L41/0253 , H04L41/0803 , H04L41/22 , H04L41/508 , H04Q2213/13034 , H04Q2213/13176 , H04Q2213/13196 , H04Q2213/13389
摘要： A multiservice network for delivering enhanced communication services to customer devices attached to either the PSTN, such as telephones and fax machines, or devices attached to the Internet or private data networks, such as PCs or other IP devices, is presented. Enhanced services include IP-based faxing, IP-based telephony, IP-based conferencing, Internet call waiting, messaging services, such as unified messaging, and other advanced services such as find-me-follow-me, and desktop telephony. The multiservice network may be managed by a configuration manager for Internet telephony (COMIT).
摘要翻译：提供了一种用于向连接到PSTN的客户设备（例如电话和传真机）或连接到因特网或专用数据网络（例如PC或其他IP设备）的设备提供增强的通信服务的多业务网络。增强的服务包括基于IP的传真，基于IP的电话，基于IP的会议，互联网呼叫等待，消息传递服务，如统一消息传递以及其他高级服务，例如我的跟踪和桌面电话。多业务网络可以由用于因特网电话（COMIT）的配置管理器来管理。

9. 发明申请

US20070026441A1 Methods for reducing viral load in HIV-1-infected patients 审中-公开
标题翻译：降低HIV-1感染患者病毒载量的方法
公开(公告)号：US20070026441A1
公开(公告)日：2007-02-01
申请号：US11491330
申请日：2006-07-21
申请人： William Olson , Paul Maddon , Daniel Pevear , Robert Israel , Jose Murga
发明人： William Olson , Paul Maddon , Daniel Pevear , Robert Israel , Jose Murga
IPC分类号： C12Q1/68 , G01N33/53
CPC分类号： A61K39/39 , A61K31/351 , A61K31/4178 , A61K31/46 , A61K31/496 , A61K31/506 , A61K31/551 , A61K31/7072 , A61K38/1709 , A61K38/195 , A61K39/39541 , A61K39/3955 , A61K2039/505 , A61K2039/55511 , C07K16/2866 , C07K2317/24 , C07K2317/76 , C12Q1/701 , A61K2300/00
摘要： This method provides a method for reducing HIV-1 viral load in an HIV-1-infected human subject which comprises administering to the subject at a predefined interval effective HIV-1 viral load-reducing doses of (a) a humanized antibody designated PRO 140, or of (b) an anti-CCR5 receptor monoclonal antibody. This invention also provides a method for inhibiting in a human subject the onset or progression of an HIV-1-associated disorder, the inhibition of which is effected by inhibiting fusion of HIV-1 to CCR5+CD4+ target cells in the subject. This invention also provides a method for treating a subject infected with HIV-1 comprising administering to the subject (a) a monoclonal antibody which (i) binds to a CCR5 receptor on the surface of the subject's CD4+ cells and (ii) inhibits fusion of HIV-1 to the subject's CCR5+CD4+ cells, and (b) a non-antibody CCR5 receptor antagonist, in amounts effective to treat the subject.
摘要翻译：该方法提供了用于降低HIV-1感染的人受试者中的HIV-1病毒载量的方法，其包括以预定间隔向受试者施用有效的HIV-1病毒载量降低剂量的（a）称为PRO140的人源化抗体，或（b）抗CCR5受体单克隆抗体。本发明还提供了一种在人类受试者中抑制HIV-1相关疾病的发生或进展的方法，其抑制通过抑制HIV-1与CCR5 + SUP> + 靶细胞。本发明还提供了用于治疗感染HIV-1的受试者的方法，其包括对受试者施用（a）单克隆抗体，所述单克隆抗体（i）与受试者的CD4 + 细胞和（ii）以有效治疗受试者的量，抑制HIV-1与受试者的CCR5 + CD4 +细胞的融合，和（b）非抗体CCR5受体拮抗剂。

10. 发明授权

US06940849B2 System and method for IP telephony ping 有权
标题翻译： IP电话ping系统和方法
公开(公告)号：US06940849B2
公开(公告)日：2005-09-06
申请号：US10417415
申请日：2003-04-16
申请人： Elliot Eichen , Robert Israel , Evegeni Belin , Robert Olshansky
发明人： Elliot Eichen , Robert Israel , Evegeni Belin , Robert Olshansky
IPC分类号： H04L12/24 , H04L12/26 , H04M3/22 , H04M3/26 , H04M7/00 , H04L12/66
CPC分类号： H04L65/80 , H04L41/0681 , H04L43/0811 , H04L43/0829 , H04L43/087 , H04L43/10 , H04L65/1069 , H04M3/2227 , H04M3/26 , H04M7/006
摘要： The present invention provides a system and method for establishing the availability of a node to received a voice over internet protocol (VoIP) call. The present invention comprises attempting to establish a VoIP call to a given node that is the target of the VoIP call, determining whether the attempt to establish the VoIP call is successful; and generating an alarm in response to a call failure. According to embodiments of the invention, the method may comprise extracting call metrics from a VoIP call that provide information regarding the quality of a VoIP connection and generating an alarm in response to the call metrics falling below a threshold.
摘要翻译：本发明提供一种用于建立节点可用性以接收互联网协议语音（VoIP）呼叫的系统和方法。本发明包括尝试建立对作为VoIP呼叫的目标的给定节点的VoIP呼叫，确定建立VoIP呼叫的尝试是否成功; 并响应于呼叫失败而产生报警。根据本发明的实施例，该方法可以包括从提供关于VoIP连接的质量的信息的VoIP呼叫中提取呼叫指标，并响应于低于阈值的呼叫度量来产生警报。

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