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    • 1. 发明授权
    • Circumferential pressure probe
    • 圆周压力探头
    • US4873990A
    • 1989-10-17
    • US248020
    • 1988-09-23
    • Harlan K. HolmesThomas C. Moore, Jr.Andrew J. Fantl
    • Harlan K. HolmesThomas C. Moore, Jr.Andrew J. Fantl
    • A61B5/03A61B5/22G01L9/00
    • G01L9/0002A61B5/036A61B5/227
    • A probe for measuring circumferential pressures inside a body cavity. In the preferred embodiment, a urodynamic pressure measurement probe for evaluating human urinary sphincter function is disclosed. Along the length of the probe are disposed a multiplicity of deformable wall sensors (15) which typically comprise support tube sections (55) with flexible side wall areas (57, 16). These are arranged along the length of the probe in two areas, one just proximal to the tip (13) for the sensing of fluid pressure inside the bladder, and five in a sensing section (14) which is positioned within the urethra at the point at which the urinary sphincter constricts to control the flow of urine. The remainder of the length of the probe comprises multiple rigid support tube sections (10) interspersed with flexible support tube sections in the form of bellows (58) to provide flexibility.
    • 用于测量体腔内周向压力的探头。 在优选实施例中,公开了一种用于评估人类尿路括约肌功能的尿动力学压力测量探针。 沿着探头的长度布置有多个可变形壁传感器(15),其通常包括具有柔性侧壁区域(57,16)的支撑管段(55)。 这些沿着探针的长度布置在两个区域中,一个刚好在尖端(13)附近,用于感测膀胱内的流体压力,并且在感测部分(14)中五个位于尿道内的位置处 其中尿括约肌收缩以控制尿液的流动。 探针的长度的其余部分包括多个刚性支撑管部分(10),其以波纹管(58)的形式散布有柔性支撑管部分以提供柔性。
    • 2. 发明授权
    • Motility analysis, display, and interpretation system
    • 运动分析,显示和口译系统
    • US06740047B2
    • 2004-05-25
    • US10054791
    • 2002-01-25
    • Harlan K. HolmesRay E. ClouseDomenic A. Bellino
    • Harlan K. HolmesRay E. ClouseDomenic A. Bellino
    • A61B500
    • A61B5/036A61B2562/0247A61B2562/043
    • The system includes an array of transducers that simultaneously senses multiple intralumenal pressures, a data acquisition module that acquires and stores samples of the measured pressures, software routines for signal analysis, a software module for multi-dimensional data display presentations, and a software module to perform pattern recognition on the acquired data set to identify potential maladies that may be indicated by the analysis. The transduction elements are cylindrical segments that deform according to the circumferential pressures encountered. Distributing a quantity of these sensor segments at desired locations along a flexible support structure and providing a flexible sheath over the entire length forms the sensor array. Measuring the sensor deformation provides an electrical analog of the pressure causing the deformation. Acquiring these measurements in a suitable data acquisition and processing unit, including a display, printing, and plotting capability, completes the hardware elements. Integrated software modules complete the system.
    • 该系统包括同时感测多个管腔内压力的传感器阵列,用于获取和存储测量压力样本的数据采集模块,用于信号分析的软件程序,用于多维数据显示呈现的软件模块和软件模块 对所获取的数据集执行模式识别,以识别可能由分析指示的潜在疾病。 转导元件是根据遇到的周向压力而变形的圆柱形段。 将这些传感器段的数量沿柔性支撑结构分布在期望的位置,并在整个长度上提供柔性护套形成传感器阵列。 测量传感器变形提供了导致变形的压力的电气模拟。 在合适的数据采集和处理单元(包括显示,打印和绘图功能)中获取这些测量结果,从而完成了硬件元件。 集成软件模块完成系统。
    • 3. 发明授权
    • Pressure sensor using liquid crystals
    • 使用液晶的压力传感器
    • US5309767A
    • 1994-05-10
    • US959931
    • 1992-10-09
    • Devendra S. ParmarHarlan K. Holmes
    • Devendra S. ParmarHarlan K. Holmes
    • G01L9/00
    • G01L9/0077
    • A pressure sensor includes a liquid crystal positioned between transparent, electrically conductive films (18 and 20), that are biased by a voltage (V) which induces an electric field (E) that causes the liquid crystal to assume a first state of orientation. Application of pressure (P) to a flexible, transparent film (24) causes the conductive film (20) to move closer to or farther from the conductive film (18), thereby causing a change in the electric field (E'(P)) which causes the liquid crystal to assume a second state of orientation. Polarized light (P.sub.1) is directed into the liquid crystal and transmitted or reflected to an analyzer (A or 30). Changes in the state of orientation of the liquid crystal induced by applied pressure (P) result in a different light intensity being detected at the analyzer (A or 30) as a function of the applied pressure (P). In particular embodiments, the liquid crystal is present as droplets (10) in a polymer matrix (12) or in cells (14) in a polymeric or dielectric grid (16) material in the form of a layer (13) between the electrically conductive films (18 and 20). The liquid crystal fills the open wells in the polymer matrix (12) or grid (16) only partially.
    • 压力传感器包括位于透明导电膜(18和20)之间的液晶,其由引起使液晶呈现第一取向状态的电场(E)的电压(V)偏置。 将压力(P)施加到柔性透明膜(24)使得导电膜(20)移动得更靠近导电膜(18)或离导电膜(18)更远,从而导致电场(E'(P) ),这导致液晶呈现第二取向状态。 偏振光(P1)被引导到液晶中并被传输或反射到分析器(A或30)。 通过施加的压力(P)引起的液晶的取向状态的变化导致在分析器(A或30)处作为施加的压力(P)的函数检测到不同的光强度。 在特定实施方案中,液晶以聚合物基体(12)中的液滴(10)或以导电(13)形式的聚合物或电介质栅格(16)材料中的电池(14)存在于导电 电影(18和20)。 液晶仅部分地填充聚合物基体(12)或网格(16)中的开孔。
    • 4. 发明授权
    • Crossflow vorticity sensor
    • 交叉涡度传感器
    • US4727751A
    • 1988-03-01
    • US3676
    • 1987-01-15
    • Bruce J. HolmesDebra L. CarrawayHarlan K. HolmesThomas C. Moore
    • Bruce J. HolmesDebra L. CarrawayHarlan K. HolmesThomas C. Moore
    • G01M9/06G01P5/12G01M9/00
    • G01M9/065G01P5/12
    • A crossflow vorticity sensor is provided for the detection of crossflow vorticity characteristics. The crossflow vorticity sensor is comprised of crossflow sensors (10) which are non-invasively adhered to swept wing laminar surface (12) either singularly, in multi-element strips (11), in polar patterns (40), or orthogonal patterns (41). These crossflow sensors (10) are comprised of hot-film sensor elements (18) which operate as a constant temperature anemometer circuit to detect heat transfer rate changes. Accordingly, crossflow vorticity characteristics are determined via cross-correlation. In addition, the crossflow sensors (10) have a thickness which does not exceed a maximum value h in order to avoid contamination of downstream crossflow sensors (10).
    • 提供交叉涡度涡度传感器用于检测交叉涡流涡度特性。 交叉流涡度传感器包括交叉流传感器(10),其以多重元件条(11),极坐标图案(40)或正交图案(41)中单独地非侵入性地粘附到扫掠翼片层表面(12) )。 这些横流传感器(10)由热膜传感器元件(18)组成,其作为恒温风速计电路来操作以检测传热速率变化。 因此,通过互相关确定交叉流动涡度特性。 此外,交叉流传感器(10)具有不超过最大值h的厚度,以避免污染下游横流传感器(10)。