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    • 6. 发明申请
    • Compositions for Improving Skin Conditions Comprising Matrine or Its Oxidized Derivatives
    • 用于改善包括苦参碱或其氧化衍生物的皮肤病症的组合物
    • US20100099698A1
    • 2010-04-22
    • US12527237
    • 2008-02-21
    • Deok Hoon ParkEun Sun JungJong Sung Lee
    • Deok Hoon ParkEun Sun JungJong Sung Lee
    • A61K8/49A61Q19/00
    • A61K8/4926A61K2800/522A61K2800/782A61Q7/00A61Q17/04A61Q19/02A61Q19/08
    • The present invention relates to a composition for improving skin conditions comprising matrine and oxymatrine as an active ingredient. Matrine and oxymatrine have lower cytotoxicity than retinol used as anti-wrinkle agents and exhibit the inhibition effect on collagenase activity and promotion effect on collagen biosynthesis at a molecular level, contributing to excellent efficacy in improvement of skin wrinkles. In addition, both matrine and oxymatrine exhibit the inhibition effect on melanin production by inhibiting intracellular tyrosinase activity, the improving effects of UV-induced skin damage and the skin growth promotion or hair loss prevention. Therefore, matrine and oxymatrine have the excellent improvement effects on skin conditions. Furthermore, matrine and oxymatrine have the excellent anti-obesity and anti-oxidation effects. The composition of this invention can be applied to cosmetic, pharmaceutical and food composition having no cytotoxicities and side effects.
    • 本发明涉及一种用于改善皮肤病症的组合物,其包含苦参碱和氧化苦参碱作为活性成分。 苦参碱和氧化苦参碱比用作抗皱剂的视黄醇具有更低的细胞毒性,并且在分子水平上表现出对胶原酶活性的抑制作用和对胶原生物合成的促进作用,有助于提高皮肤皱纹的优异疗效。 此外,苦参碱和氧化苦参碱都通过抑制细胞内酪氨酸酶活性,改善UV诱导的皮肤损伤和皮肤生长促进或减少脱发的效果来显示对黑色素产生的抑制作用。 因此,苦参碱和氧化苦参碱对皮肤状况有极好的改善作用。 此外,苦参碱和氧化苦参碱具有优异的抗肥胖和抗氧化作用。 本发明的组合物可以应用于没有细胞毒性和副作用的化妆品,药​​物和食品组合物。
    • 9. 发明申请
    • JAVA BYTECODE TRANSLATING METHOD
    • JAVA BYTECODE TRANSLATING方法
    • US20100064276A1
    • 2010-03-11
    • US12514430
    • 2008-08-19
    • Jong Sung LeeHyeong Cheol OhHyun Gyu KimKwan Young Kim
    • Jong Sung LeeHyeong Cheol OhHyun Gyu KimKwan Young Kim
    • G06F9/44
    • G06F9/30174G06F9/44521G06F9/45508
    • Provided is a Java bytecode translating method which includes: a bytecode fetch step (S1 10) that fetches a Java bytecode from a Java class file; a static field address detection and data processing step (S140) which gains access to a field (130) according to a first field address (FA1) and processes data; a static field address storage step (S 150) that stores a first upper field address (FAU1) including upper bits among bits of the first field address (FA1) in a first storage portion (110), and which stores a first lower field address (FAD1) including remainder lower bits excluding the first upper field address (FAU1) among the bits of the first field address (FA1) in an operand field (120b); a static operation code translating step (S 160) that translates an operation code stored in an operation code field (120a) into a new static field accessing operation code (NOPA); a first field address creation step (S240) that creates a second field address (FA2); and a first data processing step (S250) that gains access to the field (130) according to a second field address (F A2) and processes data.
    • 提供了一种Java字节码翻译方法,其包括:从Java类文件获取Java字节码的字节码获取步骤(S110); 静态场地址检测和数据处理步骤(S140),其根据第一字段地址(FA1)访问字段(130)并处理数据; 静态场地址存储步骤(S150),其在第一存储部分(110)中存储包括第一字段地址(FA1)的比特之中的高位的第一上场地址(FAU1),并且存储第一下场地址 (FAD1),包括除了操作数字段(120b)中的第一字段地址(FA1)的位之外的除了第一上场地址(FAU1)之外的其余较低位; 将存储在操作码字段(120a)中的操作代码转换为新的静态字段访问操作码(NOPA)的静态操作码转换步骤(S160); 创建第二字段地址(FA2)的第一字段地址创建步骤(S240); 以及根据第二字段地址(F A2)获得对字段(130)的访问并处理数据的第一数据处理步骤(S250)。