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1. 发明授权

US07799965B2 Wound dressings with anti-microbial and zinc-containing agents 有权
标题翻译：伤口敷料用抗微生物剂和含锌剂
公开(公告)号：US07799965B2
公开(公告)日：2010-09-21
申请号：US11783668
申请日：2007-04-11
申请人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemontagne , E. David Fink , Ronald F. Vitaris , Chirag B. Shah , Sharon A. Mulligan , Brian Dowd , Scott Orr
发明人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemontagne , E. David Fink , Ronald F. Vitaris , Chirag B. Shah , Sharon A. Mulligan , Brian Dowd , Scott Orr
IPC分类号： A61F13/00 , A61L15/16
CPC分类号： A61L15/44 , A61F13/00029 , A61F13/00063 , A61F2013/00463 , A61F2013/00727 , A61F2013/0091 , A61L15/18 , A61L15/46 , A61L2300/102 , A61L2300/104 , A61L2300/206 , A61L2300/404 , A61L2300/61
摘要： A wound dressing includes one or more layers containing a first anti-microbial agent and/or at least one zinc-containing agent.
摘要翻译：伤口敷料包括含有第一抗微生物剂和/或至少一种含锌剂的一层或多层。

2. 发明授权

US07750201B2 Wound dressings with anti-microbial and chelating agents 有权
标题翻译：伤口敷料用抗微生物剂和螯合剂
公开(公告)号：US07750201B2
公开(公告)日：2010-07-06
申请号：US11783667
申请日：2007-04-11
申请人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemontagne , E. David Fink , Ronald F. Vitaris , Chirag B. Shah , Sharon A. Mulligan , Brian Dowd , Scott Orr
发明人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemontagne , E. David Fink , Ronald F. Vitaris , Chirag B. Shah , Sharon A. Mulligan , Brian Dowd , Scott Orr
IPC分类号： A61F13/00 , A61L15/16
CPC分类号： A61L15/46 , A61F13/00029 , A61F13/00063 , A61F2013/00463 , A61F2013/00472 , A61F2013/00608 , A61F2013/0091 , A61F2013/00927 , A61F2013/00936 , A61L15/18 , A61L15/20 , A61L2300/102 , A61L2300/206 , A61L2300/404 , A61L2300/61
摘要： A wound dressing includes one or more layers containing a first anti-microbial agent and at least one of: a chelating agent, and a second anti-microbial agent.
摘要翻译：伤口敷料包括含有第一抗微生物剂和至少一种螯合剂和第二抗微生物剂的一层或多层。

3. 发明申请

US20100260824A1 Antimicrobial Foam Compositions, Articles and Methods 审中-公开
标题翻译：抗菌泡沫组合物，文章和方法
公开(公告)号：US20100260824A1
公开(公告)日：2010-10-14
申请号：US12548532
申请日：2009-08-27
申请人： Chirag B. Shah , Ronald F. Vitaris , E. David Fink , Scott Orr , Brian Dowd , Alain Tranchemontagne , Kate Ward , Hansen Swaniker , Harish A. Patel
发明人： Chirag B. Shah , Ronald F. Vitaris , E. David Fink , Scott Orr , Brian Dowd , Alain Tranchemontagne , Kate Ward , Hansen Swaniker , Harish A. Patel
IPC分类号： A61L15/16 , A61K31/785 , A61K38/02 , A61P17/02
CPC分类号： A01N25/00 , A01N25/34 , A61F13/0203 , A61F2013/0091 , A61L15/425 , A61L15/46 , A61L2300/206 , A61L2300/208 , A61L2300/404 , A61L2300/608 , A01N33/12 , A01N47/44
摘要： Articles may be formed including: at least one layer of foam, the foam layer and at least one antimicrobial agent associated with foam layer, the antimicrobial agent including PHMB, PEHMB, or derivatives thereof; at least one non-adherent layer disposed on at least a portion of the foam layer, the non-adherent layer being permeable to moisture; and a film disposed on at least another portion of the foam layer, the film being breathable to allow escape of moisture, but substantially impermeable to bacteria. Another article may include at least one layer of foam, the foam having pores of different sizes, at least some of the pores at least partially filled with at least one elutable antimicrobial agent, the pores of different sizes forming a gradient with the foam layer. Yet another article may include a foam matrix and a plurality of dissolvable members disposed with the foam matrix, at least one antimicrobial agents associated with the dissolvable members such that upon dissolution thereof the antimicrobial agent is eluted and pores or voids are created in the foam matrix. Wound dressings formed from the above articles are also described.
摘要翻译：可以形成制品，包括：至少一层泡沫，泡沫层和与泡沫层相关的至少一种抗微生物剂，抗微生物剂包括PHMB，PEHMB或其衍生物; 至少一个非粘附层设置在泡沫层的至少一部分上，非粘附层可渗透水分; 以及设置在泡沫层的至少另一部分上的膜，所述膜是透气的，以允许水分逸出，但是对细菌基本上不可渗透。另一制品可以包括至少一层泡沫，泡沫具有不同尺寸的孔，至少部分至少部分填充有至少一种可消除的抗微生物剂的孔，不同尺寸的孔与泡沫层形成梯度。另一种制品可以包括泡沫基质和与泡沫基体一起设置的多个可溶解构件，至少一种与可溶解构件相关联的抗微生物剂，使得在溶解时，抗微生物剂被洗脱，并且在泡沫基质中产生孔或空隙。还描述了由上述制品形成的伤口敷料。

4. 发明申请

US20100055158A1 Environmentally Activated Compositions, Articles and Methods 审中-公开
标题翻译：环保活性成分，文章和方法
公开(公告)号：US20100055158A1
公开(公告)日：2010-03-04
申请号：US12550045
申请日：2009-08-28
申请人： Ronald F. Vitaris , Harish A. Patel , E. David Fink , Sharon A. Mulligan , Brian Dowd , Scott Orr , Chirag B. Shah
发明人： Ronald F. Vitaris , Harish A. Patel , E. David Fink , Sharon A. Mulligan , Brian Dowd , Scott Orr , Chirag B. Shah
IPC分类号： A61K9/70 , A01N33/12 , A61K31/155 , A61K38/02 , A61P17/02 , A61P31/04 , A61P31/02
CPC分类号： A61L15/46 , A61F13/00012 , A61F13/00063 , A61F13/0213 , A61F13/0226 , A61F13/0253 , A61F2013/00412 , A61F2013/00846 , A61F2013/0091 , A61L15/325 , A61L15/58 , A61L2300/114 , A61L2300/206 , A61L2300/404 , A61L2300/608 , A61M35/00
摘要： An article includes a film layer; at least one layer of adhesive on at least one side of the film layer; a patch or strip comprising at least one antimicrobial agent, the patch or strip disposed on the same side of the film layer as the at least one layer of adhesive; and a relatively non-flexible sheet releasably attached to the side of the film layer opposite to the patch or strip. Alternatively, an article includes a film layer; a collagen layer; and a biodegradable hydrogel layer comprising PHMB; wherein the biodegradable hydrogel layer comprising PHMB is disposed between the film layer and the collagen layer
摘要翻译：一篇文章包括一个薄膜层; 在所述膜层的至少一侧上的至少一层粘合剂; 包括至少一种抗微生物剂的贴片或条带，所述贴片或条带设置在与所述至少一层粘合剂的膜层相同的一侧上; 以及可释放地附接到膜片与贴片或条带相对的一侧的相对非柔性片。或者，制品包括膜层; 胶原层; 和包含PHMB的可生物降解的水凝胶层; 其中包含PHMB的生物降解性水凝胶层设置在所述膜层和所述胶原层之间

5. 发明申请

US20120177720A1 MULTI-LAYER WOUND DRESSINGS 审中-公开
标题翻译：多层连衣裙
公开(公告)号：US20120177720A1
公开(公告)日：2012-07-12
申请号：US13426134
申请日：2012-03-21
申请人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemotagne
发明人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemotagne
IPC分类号： A61K9/70 , A61K38/39 , A61K33/30 , A61K31/155 , A61K31/734 , A61K38/12 , A61K33/42 , A61K31/315 , A61P29/00 , A61P7/04 , A61P7/02 , A61P23/00 , A61P35/00 , A61P9/08 , A61P17/02 , A61P9/00 , A61P37/04 , A61P31/04 , A61P31/00 , A61K38/43
CPC分类号： A61L15/46 , A61L2300/102 , A61L2300/206 , A61L2300/404 , A61L2300/45 , A61L2300/608
摘要： A wound dressing includes one or more layers containing a first anti-microbial agent and optionally at least one of: a chelating agent, a second anti-microbial agent, a zinc-containing agent, a cell-signaling agent, and an additional active ingredient or agent.
摘要翻译：伤口敷料包括含有第一抗微生物剂和任选的至少一种螯合剂，第二抗微生物剂，含锌剂，细胞信号传导剂和另外的活性成分的一层或多层或代理。

6. 发明申请

US20070237812A1 Multi-layer wound dressings 审中-公开
标题翻译：多层伤口敷料
公开(公告)号：US20070237812A1
公开(公告)日：2007-10-11
申请号：US11716008
申请日：2007-03-09
申请人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemotagne
发明人： Harish A. Patel , Hansen P. Swaniker , David G. Heagle , Kate Ward , Alain Tranchemotagne
IPC分类号： A61L15/16
CPC分类号： A61L15/46 , A61L2300/102 , A61L2300/206 , A61L2300/404 , A61L2300/45 , A61L2300/608
摘要： A wound dressing includes one or more layers containing a first anti-microbial agent and optionally at least one of: a chelating agent, a second anti-microbial agent, a zinc-containing agent, a cell-signaling agent, and an additional active ingredient or agent.
摘要翻译：伤口敷料包括含有第一抗微生物剂和任选的至少一种螯合剂，第二抗微生物剂，含锌剂，细胞信号传导剂和另外的活性成分的一层或多层或代理。

7. 发明授权

US08672906B2 Medical dressing containing antimicrobial agent and related methods therefor 有权
标题翻译：含抗微生物剂的医用敷料及其相关方法
公开(公告)号：US08672906B2
公开(公告)日：2014-03-18
申请号：US13330092
申请日：2011-12-19
申请人： Harish A. Patel
发明人： Harish A. Patel
IPC分类号： A61F13/00
CPC分类号： A61L15/225 , A61F13/00008 , A61F13/00029 , A61F13/00063 , A61F2013/00604 , A61F2013/0091 , A61L15/44 , A61L15/46
摘要： A medical dressing containing an antimicrobial agent is disclosed. The medical dressing comprises a layered fabric comprising an inner layer of substantially hydrophilic material, an outer layer of substantially hydrophobic material on both sides of the inner layer; and an antimicrobial agent. The antimicrobial agent may be releasably impregnated into the fabric, coated on said fabric or a combination thereof. The antimicrobial agent may be a biguanide, such as polyhexamethylene biguanide (PHMB). The fabric inner layer material may be substantially a cellulose fiber, preferably substantially rayon, and the fabric outer layer material may be substantially polyester, e.g., a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber. The fabric is preferably treated with an aqueous solution of surfactant and PHMB to have about 1500-3500 ppm of extractable PHMB.
摘要翻译：公开了含有抗微生物剂的医用敷料。医用敷料包括层状织物，其包含基本上亲水性材料的内层，在内层两侧的基本上疏水性材料的外层; 和抗微生物剂。抗微生物剂可以可剥离地浸渍到织物中，涂覆在所述织物上或其组合。抗微生物剂可以是双胍，如聚六亚甲基双胍（PHMB）。织物内层材料可以基本上是纤维素纤维，优选基本上是人造纤维，并且织物外层材料可以是基本上聚酯，例如织物基质级聚酯纤维和无定形粘合剂级聚酯纤维的组合。织物优选用表面活性剂和PHMB的水溶液处理以具有约1500-3500ppm的可萃取PHMB。

8. 发明授权

US08444612B2 Self contained wound dressing apparatus 有权
标题翻译：自包含伤口敷料器
公开(公告)号：US08444612B2
公开(公告)日：2013-05-21
申请号：US12879715
申请日：2010-09-10
申请人： Harish A. Patel , Dianne Acheson
发明人： Harish A. Patel , Dianne Acheson
IPC分类号： A61M1/00
CPC分类号： A61M27/00 , A61F13/00063 , A61F13/00068 , A61F2013/00174 , A61F2013/00412 , A61F2013/00536 , A61F2013/0054 , A61F2013/0074 , A61F2013/00748 , A61F2013/0091 , A61M1/0031 , A61M1/0066 , A61M1/0072 , A61M1/0088 , A61M1/009 , A61M1/0096 , A61M2205/15 , A61M2205/3344 , A61M2205/8206 , A61M2209/08 , A61M2209/088
摘要： The composite wound dressing apparatus promotes healing of a wound via the use of a vacuum pump. The vacuum pump applies a vacuum pressure to the wound to effectively draw wound fluid or exudate away from the wound bed. The vacuum pump is tethered to the wound dressing and is portable, preferably, carried by the patient in a support bag, which permits patient mobility. Moreover, the patient does not need to be constrained for any period of time while exudate is being removed from the wound.
摘要翻译：复合伤口敷料装置通过使用真空泵促进伤口愈合。真空泵对伤口施加真空压力，以有效地将伤口液体或渗出物从伤口床上吸出。真空泵被连接到伤口敷料上，并且是便携式的，优选地由患者携带在支撑袋中，这允许患者移动。此外，患者不需要约束任何时间段，而渗出物被从伤口移除。

9. 发明授权

US4397315A Dressing with temperature pack 失效
标题翻译：敷裹温度包
公开(公告)号：US4397315A
公开(公告)日：1983-08-09
申请号：US302917
申请日：1981-09-16
申请人： Harish A. Patel
发明人： Harish A. Patel
IPC分类号： A61F7/00 , A61F7/02 , A61F7/03 , A61M25/00
CPC分类号： A61F7/03 , A61F2007/0028 , A61F2007/0257 , A61F2007/026 , A61F2007/0276
摘要： A dressing for the body of a patient comprising, an elongated pack to produce heat or cold. The pack has a front surface and a rear surface. The dressing has an absorbent medium at least substantially covering the front and rear surface of the pack.
摘要翻译：用于患者身体的敷料，包括用于产生热或冷的细长包装。该组件具有前表面和后表面。该敷料具有至少基本上覆盖该包的前表面和后表面的吸收剂介质。

10. 发明申请

US20120089069A1 Medical Dressing Containing Antimicrobial Agent And Related Methods Therefor 有权
标题翻译：含有抗微生物剂的医用敷料及其相关方法
公开(公告)号：US20120089069A1
公开(公告)日：2012-04-12
申请号：US13330092
申请日：2011-12-19
申请人： Harish A. Patel
发明人： Harish A. Patel
IPC分类号： A61L15/44
CPC分类号： A61L15/225 , A61F13/00008 , A61F13/00029 , A61F13/00063 , A61F2013/00604 , A61F2013/0091 , A61L15/44 , A61L15/46
摘要： A medical dressing containing an antimicrobial agent is disclosed. The medical dressing comprises a layered fabric comprising an inner layer of substantially hydrophilic material, an outer layer of substantially hydrophobic material on both sides of the inner layer; and an antimicrobial agent. The antimicrobial agent may be releasably impregnated into the fabric, coated on said fabric or a combination thereof. The antimicrobial agent may be a biguanide, such as polyhexamethylene biguanide (PHMB). The fabric inner layer material may be substantially a cellulose fiber, preferably substantially rayon, and the fabric outer layer material may be substantially polyester, e.g., a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber. The fabric is preferably treated with an aqueous solution of surfactant and PHMB to have about 1500-3500 ppm of extractable PHMB.
摘要翻译：公开了含有抗微生物剂的医用敷料。医用敷料包括层状织物，其包含基本上亲水性材料的内层，在内层两侧的基本上疏水性材料的外层; 和抗微生物剂。抗微生物剂可以可剥离地浸渍到织物中，涂覆在所述织物上或其组合。抗微生物剂可以是双胍，如聚六亚甲基双胍（PHMB）。织物内层材料可以基本上是纤维素纤维，优选基本上是人造纤维，并且织物外层材料可以是基本上聚酯，例如织物基质级聚酯纤维和无定形粘合剂级聚酯纤维的组合。织物优选用表面活性剂和PHMB的水溶液处理以具有约1500-3500ppm的可萃取PHMB。

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