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1. 发明申请

US20110166420A1 IMAGING METHOD AND APPARATUS 审中-公开
标题翻译：成像方法和装置
公开(公告)号：US20110166420A1
公开(公告)日：2011-07-07
申请号：US12756692
申请日：2010-04-08
申请人： Hans-Joachim Miesner , Christoph Hauger , Werner Nahm , Frank Rudolph , Guido Hattendorf , Peter Maxwell Delaney , John D. Allen
发明人： Hans-Joachim Miesner , Christoph Hauger , Werner Nahm , Frank Rudolph , Guido Hattendorf , Peter Maxwell Delaney , John D. Allen
IPC分类号： A61B1/06
CPC分类号： A61B1/00078 , A61B1/00009 , A61B1/00041 , A61B1/00045 , A61B1/0005 , A61B1/0008 , A61B1/00172 , A61B1/042 , A61B1/06 , A61B1/227 , A61B1/233 , A61B1/267 , A61B1/313 , A61B5/0066 , A61B5/0068 , A61B5/0075 , A61B5/0084 , A61B5/064 , A61B5/065 , A61B5/6835 , A61B5/6852 , A61B5/6855 , A61B7/02 , A61B8/12 , A61B90/90 , A61B90/92 , A61B90/94 , G02B21/0028 , G02B23/2476
摘要： An imaging apparatus and method are provided. The probe for an imaging apparatus includes a manually manipulable proximal portion; a straight distal portion with a distal tip for locating at a site to define an observational field; and a curved portion between the proximal portion and the distal portion. The imaging method includes the steps of locating a distal tip of an imaging probe at a site to define an observational field; irradiating the observational field from the distal tip; and collecting a return signal at the distal tip; wherein the probe comprises a manually manipulable proximal portion. The apparatus and method provided herein are useful for various applications including but not limited to endomicroscopy and other microsurgical procedures performed under optical stereoscopic magnified visualization, such as neurosurgery, ENT/facial surgery and spinal surgery.
摘要翻译：提供了一种成像装置和方法。用于成像装置的探针包括手动可操纵的近端部分; 具有远端的直的远端部分，用于定位在现场以限定观察场; 以及在近端部分和远端部分之间的弯曲部分。该成像方法包括以下步骤：将成像探针的远侧末端定位在位置以限定观察场; 从远端照射观察场; 并在远端收集返回信号; 其中所述探针包括可手动操作的近端部分。本文提供的装置和方法可用于各种应用，包括但不限于在光学立体放大显微镜（例如神经外科手术，ENT /面部手术和脊柱手术）下执行的内窥镜和其他显微外科手术。

2. 发明申请

US20110178395A1 IMAGING METHOD AND SYSTEM 审中-公开
标题翻译：成像方法与系统
公开(公告)号：US20110178395A1
公开(公告)日：2011-07-21
申请号：US12756765
申请日：2010-04-08
申请人： Hans-Joachim Miesner , Christoph Hauger , Werner Nahm , Frank Rudolph , Guido Hattendorf , Peter M. Delaney , John D. Allen
发明人： Hans-Joachim Miesner , Christoph Hauger , Werner Nahm , Frank Rudolph , Guido Hattendorf , Peter M. Delaney , John D. Allen
IPC分类号： A61B6/00
CPC分类号： A61B5/064 , A61B1/00041 , A61B1/0005 , A61B1/0008 , A61B1/00096 , A61B1/00149 , A61B1/00172 , A61B1/042 , A61B1/313 , A61B5/0066 , A61B5/0068 , A61B5/0084 , A61B5/065 , A61B5/445 , A61B5/6835 , A61B5/6852 , A61B5/6855 , A61B8/12 , A61B8/4245 , A61B8/5238 , A61B34/20 , A61B90/20 , A61B90/36 , A61B2090/364 , A61B2562/0242 , G02B21/0012 , G02B21/0024
摘要： Imaging systems and methods are provided herein. An imaging system for imaging a surgical site, may include a macroscopic visualization system; and an imaging apparatus with a probe, the imaging apparatus being adapted to image the observational field and generate second image data; wherein the system is operable to control the macroscopic visualization system and the imaging apparatus to image the site and the observational field respectively at substantially the same time, and to associate the first image data and the second image data. Imaging methods provided herein may include the steps of: imaging the site with a macroscopic visualization system and generating first image data; imaging at substantially the same time an observational field with an imaging apparatus and generating second image data; and associating the first image data and the second image data.
摘要翻译：本文提供成像系统和方法。用于成像外科手术部位的成像系统可以包括宏观可视化系统; 以及具有探针的成像装置，所述成像装置适于对所述观察场进行成像并生成第二图像数据; 其中所述系统可操作以控制所述宏观可视化系统和所述成像装置，以在基本相同的时间分别对所述场地和所述观测场进行成像，并且将所述第一图像数据和所述第二图像数据相关联。本文提供的成像方法可以包括以下步骤：用宏观可视化系统对站点进行成像并产生第一图像数据; 在大体上相同的时间成像具有成像装置的观察场并产生第二图像数据; 以及将所述第一图像数据和所述第二图像数据相关联。

3. 发明申请

US20110028850A1 Process for quantitative display of blood flow 审中-公开
标题翻译：定量显示血流量的过程
公开(公告)号：US20110028850A1
公开(公告)日：2011-02-03
申请号：US12462038
申请日：2009-07-28
申请人： Thomas Schuhrke , Guenter Meckes , Joachim Steffen , Hans-Joachim Miesner , Frank Rudolph , Werner Nahm
发明人： Thomas Schuhrke , Guenter Meckes , Joachim Steffen , Hans-Joachim Miesner , Frank Rudolph , Werner Nahm
IPC分类号： A61B6/00 , A61B5/02
CPC分类号： A61B5/0261 , A61B5/0059 , A61B5/0275 , G06T7/0016 , G06T11/00 , G06T2207/10016 , G06T2207/10048 , G06T2207/30104
摘要： A method for the quantitative representation of the blood flow in a tissue or vascular region is based on the signal of a contrast agent injected into the blood. In the method, several individual images of the signal emitted by the tissue or vascular region are recorded at successive points in time and are stored. Based on the respective signal, a quantity characteristic for the blood flow and a quantity characteristic for the position of the blood vessels are determined for image areas of individual images. These quantities are represented superimposed for the respective image areas such that both the blood flow quantity and the position of the fine blood vessels become clearly visible in the representation and can be differentiated from the tissue.
摘要翻译：用于定量表示组织或血管区域中的血液流动的方法基于注射到血液中的造影剂的信号。在该方法中，在连续的时间点记录由组织或血管区域发射的信号的几个单独的图像，并被存储。基于各信号，针对各图像的图像区域确定血流的量特性和血管位置的量特征。这些量对于各个图像区域被叠加，使得血液流量和细小血管的位置在表示中变得清晰可见，并且可以与组织区分开。

4. 发明申请

US20100069759A1 Method for the quantitative display of blood flow 审中-公开
标题翻译：定量显示血流量的方法
公开(公告)号：US20100069759A1
公开(公告)日：2010-03-18
申请号：US12462036
申请日：2009-07-28
申请人： Thomas Schuhrke , Guenter Meckes , Joachim Steffen , Hans-Joachim Miesner , Frank Rudolph , Werner Nahm
发明人： Thomas Schuhrke , Guenter Meckes , Joachim Steffen , Hans-Joachim Miesner , Frank Rudolph , Werner Nahm
IPC分类号： A61B6/00 , G06K9/00
CPC分类号： A61B5/0275 , A61B5/0261 , A61B5/7207 , G06T5/50 , G06T7/33 , G06T2207/10056 , G06T2207/10064 , G06T2207/30104
摘要： A method for the quantitative representation of the blood flow in a tissue or vascular region is based on the signal of a contrast agent injected into the blood. Several individual images of the signal emitted by the tissue or vascular region are recorded and stored at successive points in time. For image areas of the individual images, the respective intensities of different points in time are compared and the maximum intensities of the signals are determined for these image areas. The maximum intensities are represented for these image areas.
摘要翻译：用于定量表示组织或血管区域中的血液流动的方法基于注射到血液中的造影剂的信号。由组织或血管区域发射的信号的几个单独图像在连续的时间点被记录并存储。对于各个图像的图像区域，比较不同时间点的相应强度，并且为这些图像区域确定信号的最大强度。对于这些图像区域表示最大强度。

5. 发明申请

US20100041999A1 Process for quantitative display of blood flow 审中-公开
标题翻译：定量显示血流量的过程
公开(公告)号：US20100041999A1
公开(公告)日：2010-02-18
申请号：US12462037
申请日：2009-07-28
申请人： Thomas Schuhrke , Guenter Meckes , Joachim Steffen , Hans-Joachim Miesner , Frank Rudolph , Werner Nahm
发明人： Thomas Schuhrke , Guenter Meckes , Joachim Steffen , Hans-Joachim Miesner , Frank Rudolph , Werner Nahm
IPC分类号： A61B6/00 , G06K9/00
CPC分类号： A61B5/0261 , A61B5/0275 , G06T7/20 , G06T11/001 , G06T2207/30104
摘要： A method for the quantitative representation of the blood flow in a tissue or vascular region based on the signal of a contrast agent injected into the blood. In the process, several individual images of the signal emitted by the tissue or vascular region are recorded at successive points in time and are stored. For image areas of stored individual images the respective point in time is determined at which the signal has exceeded a certain threshold value and this point in time is represented for each of the image areas.
摘要翻译：基于注射到血液中的造影剂的信号定量表示组织或血管区域中的血流的方法。在该过程中，在连续的时间点记录由组织或血管区域发射的信号的几个单独图像并被存储。对于存储的各个图像的图像区域，确定相应的时间点，信号已经超过了某个阈值，并且针对每个图像区域表示了该时间点。

6. 发明申请

US20070165302A1 Mouth switch arrangement and microscopy system having a mouth switch 有权
标题翻译：口开关布置和显微镜系统具有开口
公开(公告)号：US20070165302A1
公开(公告)日：2007-07-19
申请号：US11588125
申请日：2006-10-26
申请人： Robert Spetzler , Hans-Joachim Miesner , Frank Rudolph
发明人： Robert Spetzler , Hans-Joachim Miesner , Frank Rudolph
IPC分类号： G02B21/00
CPC分类号： G02B21/0012
摘要： A microscopy assembly comprises a stand, a stereo microscope supported by the stand, and a mouth switch assembly mounted to a holder, the mouth switch assembly including a mouth piece grippable by a user's teeth, and with a force sensor actuatable by the exertion of pressure by a user's lip while the mouth piece is held by the user's teeth, the force sensor including an actuating element arranged at a side of the mouth piece, wherein an actuating area of the actuating element located next to a front end of the mouth piece is spaced apart from the front end of the mouth piece by a distance larger than 4 mm and smaller than 35 mm.
摘要翻译：显微镜组件包括支架，由支架支撑的立体显微镜和安装到保持器的口开关组件，嘴开关组件包括可由使用者的牙齿夹持的口部件，以及通过施加压力可致动的力传感器当使用者的嘴部被使用者的牙齿保持时，用户的唇部，力传感器包括布置在口部件侧面的致动元件，其中位于口部件前端的致动元件的致动区域是与嘴部的前端间隔开大于4mm且小于35mm的距离。

7. 发明授权

US07933066B2 Surgical microscope having an illuminating arrangement 有权
标题翻译：具有照明装置的手术显微镜
公开(公告)号：US07933066B2
公开(公告)日：2011-04-26
申请号：US11892443
申请日：2007-08-23
申请人： Joachim Steffen , Michael Haisch , Frank Rudolph , Martin Schneider , Hans-Joachim Miesner , Nicole Brune
发明人： Joachim Steffen , Michael Haisch , Frank Rudolph , Martin Schneider , Hans-Joachim Miesner , Nicole Brune
IPC分类号： G02B21/06
CPC分类号： G02B6/4298 , G02B21/0012 , G02B21/06
摘要： A surgical microscope (100) is especially suited for use in neurosurgery. The surgical microscope has an illuminating arrangement (101) for making available illuminating light in an operating region (117) to be examined with the surgical microscope (100). The illuminating arrangement (101) contains a high-power light source (102) which includes an intensity adjusting device (112). The intensity adjusting device (112) makes possible to adjust the intensity of the illuminating light (116), which is guided to the object region (117), between a maximum value and a minimum value. The surgical microscope (100) has a control unit (170) for the illuminating arrangement (101) which includes an operator-controlled module (172) via which the illuminating arrangement (101) can be activated and controlled. For adjusting the intensity of the illuminating light (116) guided to the operating region (117), the control unit coacts with the adjustable filter unit (112). A signal generator (175) is provided which outputs a warning signal when an intensity of the illuminating light is adjusted via the operator-controlled module (172) which exceeds the safety limit value stored in a memory (171).
摘要翻译：手术显微镜（100）特别适用于神经外科手术。手术显微镜具有用于在手术显微镜（100）检查的操作区域（117）中提供照明光的照明装置（101）。照明装置（101）包括包括强度调节装置（112）的高功率光源（102）。强度调节装置（112）能够将被引导到物体区域（117）的照明光（116）的强度调整在最大值和最小值之间。所述手术显微镜（100）具有用于所述照明装置（101）的控制单元（170），所述控制单元包括操作者控制模块，通过所述操作者控制模块可以启动和控制所述照明装置。为了调节被引导到操作区域（117）的照明光（116）的强度，控制单元与可调滤光单元（112）共同作用。提供信号发生器（175），当通过超过存储在存储器（171）中的安全极限值的操作者控制模块（172）调节照明光的强度时，输出警告信号。

8. 发明申请

US20080049314A1 Surgical microscope having an illuminating arrangement 有权
标题翻译：具有照明装置的手术显微镜
公开(公告)号：US20080049314A1
公开(公告)日：2008-02-28
申请号：US11892443
申请日：2007-08-23
申请人： Joachim Steffen , Michael Haisch , Frank Rudolph , Martin Schneider , Hans-Joachim Miesner , Nicole Brune
发明人： Joachim Steffen , Michael Haisch , Frank Rudolph , Martin Schneider , Hans-Joachim Miesner , Nicole Brune
IPC分类号： G02B21/06 , A61B19/00 , A61B3/13
CPC分类号： G02B6/4298 , G02B21/0012 , G02B21/06
摘要： A surgical microscope (100) is especially suited for use in neurosurgery. The surgical microscope has an illuminating arrangement (101) for making available illuminating light in an operating region (117) to be examined with the surgical microscope (100). The illuminating arrangement (101) contains a high-power light source (102) which includes an intensity adjusting device (112). The intensity adjusting device (112) makes possible to adjust the intensity of the illuminating light (116), which is guided to the object region (117), between a maximum value and a minimum value. The surgical microscope (100) has a control unit (170) for the illuminating arrangement (101) which includes an operator-controlled module (172) via which the illuminating arrangement (101) can be activated and controlled. For adjusting the intensity of the illuminating light (116) guided to the operating region (117), the control unit coacts with the adjustable filter unit (112). A signal generator (175) is provided which outputs a warning signal when an intensity of the illuminating light is adjusted via the operator-controlled module (172) which exceeds the safety limit value stored in a memory (171).
摘要翻译：手术显微镜（100）特别适用于神经外科手术。手术显微镜具有用于在手术显微镜（100）检查的操作区域（117）中提供照明光的照明装置（101）。照明装置（101）包括包括强度调节装置（112）的高功率光源（102）。强度调节装置（112）能够将被引导到物体区域（117）的照明光（116）的强度调整在最大值和最小值之间。所述手术显微镜（100）具有用于所述照明装置（101）的控制单元（170），所述控制单元包括操作者控制模块，通过所述操作者控制模块可以启动和控制所述照明装置。为了调节被引导到操作区域（117）的照明光（116）的强度，控制单元与可调滤光单元（112）共同作用。提供信号发生器（175），当通过超过存储在存储器（171）中的安全极限值的操作者控制模块（172）调节照明光的强度时，输出警告信号。

9. 发明申请

US20110164315A1 Surgical Microscope having an Illuminating Arrangement 有权
标题翻译：具有照明装置的手术显微镜
公开(公告)号：US20110164315A1
公开(公告)日：2011-07-07
申请号：US13051545
申请日：2011-03-18
申请人： Joachim Steffen , Michael Haisch , Frank Rudolph , Martin Schneider , Hans-Joachim Miesner , Nicole Brune
发明人： Joachim Steffen , Michael Haisch , Frank Rudolph , Martin Schneider , Hans-Joachim Miesner , Nicole Brune
IPC分类号： G02B21/06
CPC分类号： G02B6/4298 , G02B21/0012 , G02B21/06
摘要： A surgical microscope (100) is especially suited for use in neurosurgery. The surgical microscope has an illuminating arrangement (101) for making available illuminating light in an operating region (117) to be examined with the surgical microscope (100). The illuminating arrangement (101) contains a high-power light source (102) which includes an intensity adjusting device (112). The intensity adjusting device (112) makes possible to adjust the intensity of the illuminating light (116), which is guided to the object region (117), between a maximum value and a minimum value. The surgical microscope (100) has a control unit (170) for the illuminating arrangement (101) which includes an operator-controlled module (172) via which the illuminating arrangement (101) can be activated and controlled. For adjusting the intensity of the illuminating light (116) guided to the operating region (117), the control unit coacts with the adjustable filter unit (112). A signal generator (175) is provided which outputs a warning signal when an intensity of the illuminating light is adjusted via the operator-controlled module (172) which exceeds the safety limit value stored in a memory (171).
摘要翻译：手术显微镜（100）特别适用于神经外科手术。手术显微镜具有用于在手术显微镜（100）检查的操作区域（117）中提供照明光的照明装置（101）。照明装置（101）包括包括强度调节装置（112）的高功率光源（102）。强度调节装置（112）能够将被引导到物体区域（117）的照明光（116）的强度调整在最大值和最小值之间。所述手术显微镜（100）具有用于所述照明装置（101）的控制单元（170），所述控制单元包括操作者控制模块，通过所述操作者控制模块可以启动和控制所述照明装置。为了调节被引导到操作区域（117）的照明光（116）的强度，控制单元与可调滤光单元（112）共同作用。提供信号发生器（175），当通过超过存储在存储器（171）中的安全极限值的操作者控制模块（172）调节照明光的强度时，输出警告信号。

10. 发明授权

US08154797B2 Surgical microscope for use in surgical procedures including neurosurgery 有权
标题翻译：手术显微镜用于外科手术，包括神经外科手术
公开(公告)号：US08154797B2
公开(公告)日：2012-04-10
申请号：US13051545
申请日：2011-03-18
申请人： Joachim Steffen , Michael Haisch , Frank Rudolph , Martin Schneider , Hans-Joachim Miesner , Nicole Brune
发明人： Joachim Steffen , Michael Haisch , Frank Rudolph , Martin Schneider , Hans-Joachim Miesner , Nicole Brune
IPC分类号： G02B21/06
CPC分类号： G02B6/4298 , G02B21/0012 , G02B21/06
摘要： A surgical microscope has an illuminating arrangement for illuminating light in an operating region to be examined with the surgical microscope. The arrangement contains a high-power light source which includes an intensity adjusting device. The device makes possible an adjustment of the intensity of the illuminating light, which is guided to the object region, between a maximum value and a minimum value. The microscope has a control unit for the illuminating arrangement which includes an operator-controlled module via which the illuminating arrangement can be activated and controlled. For adjusting the intensity of the illuminating light guided to the operating region, the control unit coacts with the adjustable filter unit. A signal generator outputs a warning signal when an intensity of the illuminating light is adjusted via the operator-controlled module which exceeds the safety limit value stored in a memory.
摘要翻译：手术显微镜具有用于在手术显微镜下照射要检查的手术区域中的光的照明装置。该装置包括高功率光源，其包括强度调节装置。该装置使得能够调整被引导到对象区域的照明光的强度在最大值和最小值之间。显微镜具有用于照明装置的控制单元，其包括操作者控制的模块，通过该模块可以启动和控制照明装置。为了调节被引导到操作区域的照明光的强度，控制单元与可调滤光单元共同作用。当通过操作者控制模块调节照明光的强度时，信号发生器输出警告信号，该操作者控制模块超过存储在存储器中的安全限制值。

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