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    • 1. 发明授权
    • Derivatives of macrolide antibiotics
    • 大环内酯类抗生素衍生物
    • US4463171A
    • 1984-07-31
    • US502480
    • 1983-06-09
    • Hamao UmezawaTomio TakeuchiKuniaki TatsutaTomoyuki IshikuraRokuro OkamotoMasao YamamotoKohki Kiyoshima
    • Hamao UmezawaTomio TakeuchiKuniaki TatsutaTomoyuki IshikuraRokuro OkamotoMasao YamamotoKohki Kiyoshima
    • A61K31/70A61K31/7042A61K31/7048A61P31/04C07H17/08
    • C07H17/08
    • Compounds of the following general formula ##STR1## wherein R.sup.1 and R.sup.2 represent a hydrogen atom or a lower alkanoyl group;R.sup.3 represents a hydrogen atom or the group --COCH.sub.2 R.sup.5 in which R.sup.5 represents a lower alkyl group or an aryl or pyridyl group bonded through a sulfur atom;R.sup.4 represents a methyl group which may be substituted by aryl, pyridyl, pyridylthio, hydroxyl or arylthioamino, an aryl group, a nitrile group, a 5- or 6-membered heterocyclic group having 1 to 4 hetero atoms selected from nitrogen and sulfur atoms, or a tetrahydropyranyl group which may be substituted by methoxy;A represents the group --OCO--, --OSO.sub.2 --, --O-- or --S--, or A and R.sup.4, taken together, represent a halogen atom, a nitrile group or a group of the formula ##STR2## in which R.sup.6 represents two lower alkyl groups, the group ##STR3## or an alkylene group having 4 to 6 carbon atoms which may have in the chain an oxygen atom or a lower alkyl-substituted nitrogen atom; and said aryl group and heterocyclic group may optionally be substituted by a methyl, methoxy or nitro group, and when R.sup.1 represents a lower alkyl group,R.sup.3 does not represent a lower alkyl group,or their salts.These novel derivatives of macrolide antibiotics have excellent antibacterial activity.
    • 下列通式的化合物:其中R 1和R 2表示氢原子或低级烷酰基; R3表示氢原子或基团-COCH2R5,其中R5表示低级烷基或通过硫原子键合的芳基或吡啶基; R 4表示可以被芳基,吡啶基,吡啶硫基,羟基或芳硫基氨基,芳基,腈基,具有1-4个选自氮和硫原子的杂原子的5或6元杂环基取代的甲基, 或可被甲氧基取代的四氢吡喃基; A代表基团-OCO-,-OSO 2 - , - O-或-S-,或A和R 4一起代表卤素原子,腈基或式(IMAGE)基团,其中R6代表二 低级烷基,基团或具有4-6个碳原子的亚烷基,其可以在链中具有氧原子或低级烷基取代的氮原子; 并且所述芳基和杂环基可任选被甲基,甲氧基或硝基取代,并且当R 1表示低级烷基时,R 3不表示低级烷基或其盐。 这些大环内酯类抗生素的新型衍生物具有优良的抗菌活性。
    • 7. 发明申请
    • Image Display Device
    • 图像显示设备
    • US20080186586A1
    • 2008-08-07
    • US11658749
    • 2005-08-09
    • Masao Yamamoto
    • Masao Yamamoto
    • G02B27/14
    • G02B27/0176
    • To improve a small image display device of the type to be attached to glasses for use, so that it can be attached to glassed of any structure.An image display device 3 has a liquid crystal display and a magnifying lens 114 contained therein. A user gets an imaging light from that display through the magnifying lens 114 to see an image. The image display device 3 includes a suction cup 160 on the back surface thereof. The suction cup 160 serves to attach it onto a smooth front surface of the glass lens included in the glasses.
    • 为了改进要附接到眼镜使用的类型的小图像显示装置,使得其可以附接到任何结构的玻璃。 图像显示装置3具有液晶显示器和放大透镜114。 用户从该显示器通过放大透镜114获得成像光以观看图像。 图像显示装置3在其背面具有吸盘160。 吸盘160用于将其附接到包括在眼镜中的玻璃透镜的光滑前表面上。
    • 8. 发明申请
    • Image Display Apparatus
    • 图像显示装置
    • US20070279318A1
    • 2007-12-06
    • US10589813
    • 2005-02-21
    • Masao Yamamoto
    • Masao Yamamoto
    • G09G5/00
    • G02B27/0172G02B27/0176G02B2027/0123G02B2027/0129G02B2027/0132G02B2027/0178H04N5/7491
    • To make images of an image display apparatus that is mounted on the head easily viewable, an image display apparatus 1 includes a main body 10 that is formed in the shape of eyeglasses. The main body 10 can be fixed onto the head of a user. The main body 10 is provided with a display device 20 that is positioned in front of a user's left eye and a shielding plate 30 that is positioned in front of the user's right eye when the main body 10 is fixed to the user's head. The display device 20 causes an image from an in-built liquid crystal display to be formed in the user's left eye to show the image to the left eye. A position in the horizontal direction and an angle in the vertical direction of the display device 20 are adjustable.
    • 为了容易地观看安装在头上的图像显示装置的图像,图像显示装置1包括形成为眼镜形状的主体10。 主体10可以固定在用户的头部上。 主体10具有位于使用者左眼前方的显示装置20和当主体10固定在使用者头部时位于使用者右眼前方的遮蔽板30。 显示装置20使来自内置液晶显示器的图像形成在用户的左眼中以向左眼显示图像。 显示装置20的水平方向的位置和垂直方向的角度是可调的。
    • 9. 发明申请
    • Camera, image processing apparatus, image data processing method, and program
    • 相机,图像处理装置,图像数据处理方法和程序
    • US20060257141A1
    • 2006-11-16
    • US10567847
    • 2004-08-13
    • Masao Yamamoto
    • Masao Yamamoto
    • G03B21/00
    • H04N9/045H04N5/23212
    • To provide a camera that is able to capture images of moving subjects as video images, that has a large depth of field and is thus able to capture images of thick objects, and that is able to capture images of living cells and tissues as well as tissues in water. An camera includes an image pickup element 134 and an objective lens 133 disposed between the image pickup element 134 and a subject. A photosensitive surface 134A of the image pickup element 134 has elements sensitive to the lights in the red, green, and blue spectral regions, respectively. In this camera, using chromatic aberration of the objective lens 133, the element that is sensitive to the light in the red spectral region receives the light in a red spectral region LR from a subject surface segment XR, the element that is sensitive to the light in the green spectral region receives the light in a green spectral region LG from a subject surface segment XG, and the element that is sensitive to the light in the blue spectral region receives the light in a blue spectral region LB from a subject surface segment XB, to form an image. The images taken by the respective elements are imaged individually and produced on a monitor.
    • 为了提供能够捕获移动被摄体的图像作为视频图像的相机,其具有大的景深,因此能够捕获厚对象的图像,并且能够捕获活细胞和组织的图像,以及 水中的组织。 相机包括图像拾取元件134和设置在图像拾取元件134和被摄体之间的物镜133。 图像拾取元件134的感光表面134A具有分别对红色,绿色和蓝色光谱区域中的光敏感的元件。 在该相机中,使用物镜133的色差,对红色光谱区域中的光敏感的元件接收来自对象表面片段XR的红色光谱区域LR中的光,对光敏感的元件 在绿色光谱区域中接收来自对象表面片段XG的绿色光谱区域LG中的光,并且对蓝色光谱区域中的光敏感的元件从受测表面片段XB接收蓝色光谱区域LB中的光 ,形成图像。 由各个元件拍摄的图像被单独成像并在监视器上产生。