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2. 发明申请

WO9907326A3 ANTIMICROBIAL CEMENT COMPOSITIONS 审中-公开
标题翻译：抗微生物水泥组合物
公开(公告)号：WO9907326A3
公开(公告)日：1999-05-20
申请号：PCT/CA9800754
申请日：1998-08-07
申请人： UNIV TORONTO , SANTERRE JOSEPH PAUL , FRIEDMAN SHIMON
发明人： SANTERRE JOSEPH PAUL , FRIEDMAN SHIMON
IPC分类号： A61K6/083 , A61L24/00 , A61K6/00
CPC分类号： A61K6/0023 , A61K6/0017 , A61K6/0656 , A61K6/0835 , A61L24/0015 , A61L2300/102 , A61L2300/104 , A61L2300/404 , A61L2300/802 , C08L33/00
摘要： Antimicrobial cement compositions are disclosed which contain antimicrobial zeolites. Preferred are antimicrobial cement compositions having dental applications including fillers, adhesives, sealants and restorative materials, and medical applications such as bone cements, implant components and bone substitutes. A particularly preferred cement is an antimicrobial glass ionomer cement composition for dental use comprising a polyelectrolyte, glass ionomer particles, and antimicrobial zeolite particles. When the composition is cured to form a hardened cement, the glass ionomer particles and the zeolite particles form ionic bonds with the polyelectrolyte, the zeolite particles being present in the composition in an amount sufficient to prevent growth of bacteria in the composition and over the hardened cement formed by curing the composition. Preferably, the zeolite contains an antimicrobial metal ion such as silver ion, and is present in the glass ionomer cement composition in an amount of from about 0.2 % to about 20 % by weight of the glass ionomer particles.
摘要翻译：公开了含有抗微生物沸石的抗微生物水泥组合物。优选的是具有牙科应用的抗微生物粘固剂组合物，包括填充剂，粘合剂，密封剂和修复材料，以及医疗应用，例如骨水泥，植入物组分和骨替代物。特别优选的水泥是用于牙科用途的抗微生物玻璃离聚物粘固剂组合物，其包含聚电解质，玻璃离聚物颗粒和抗微生物沸石颗粒。当组合物固化以形成硬化的水泥时，玻璃离聚物颗粒和沸石颗粒与聚电解质形成离子键，沸石颗粒以足以防止组合物中的细菌生长和在硬化层上生长的量存在于组合物中通过固化组合物而形成的水泥。优选地，沸石含有抗菌金属离子如银离子，并且以玻璃离聚物颗粒的约0.2重量％至约20重量％的量存在于玻璃离聚物接合剂组合物中。

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