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2. 发明申请

US20100138952A1 GENE PROMOTER REGULATORY ELEMENT ANALYSIS COMPUTATIONAL METHODS AND THEIR USE IN TRANSGENIC APPLICATIONS 审中-公开
标题翻译：基因推广法规元素分析计算方法及其在转基因应用中的应用
公开(公告)号：US20100138952A1
公开(公告)日：2010-06-03
申请号：US12534471
申请日：2009-08-03
申请人： CARL R. SIMMONS , PEDRO A. NAVARRO ACEVEDO
发明人： CARL R. SIMMONS , PEDRO A. NAVARRO ACEVEDO
IPC分类号： C12N15/82 , G06N5/02
CPC分类号： C12N15/8216 , G16B20/00 , G16B30/00
摘要： A computer-assisted method of identifying regulatory elements includes receiving a first orthologous species sequence, receiving a word length, receiving a relative offset, and receiving at least one additional orthologous species sequences, wherein each of the orthologous species sequences is associated with a species, and each of the species is an orthologous species. The method further includes performing a pairwise comparison between each pair of orthologous species sequences, computing using a computing device, overlapping portions of the sequence overlapping the sequences of all of the orthologous species sequences within the relative offset and greater than or equal to the word length.The method further includes providing an output to a user identifying the overlapping portions of the sequence for all of the orthologous species sequences to identify candidate regulatory elements.
摘要翻译：识别调节元件的计算机辅助方法包括接收第一直系同源物种序列，接收字长度，接收相对偏移量，以及接收至少一个额外的直系同源物种序列，其中每个直系同源物种序列与物种相关联，并且每个物种是直系同源物种。所述方法还包括在每对直系同源物种序列之间进行成对比较，使用计算装置进行计算，所述序列的重叠部分与相对偏移量内的所有直系同源物种序列的序列重叠并且大于或等于所述字长。所述方法还包括向用户提供输出，以识别所有直系同源物种序列的序列的重叠部分以识别候选调节元件。

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