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    • 10. 发明申请
    • PROCESS FOR PRODUCING OIL-IN-WATER EMULSIONS
    • 用于生产油包水乳液
    • WO1995011660A1
    • 1995-05-04
    • PCT/EP1994003457
    • 1994-10-20
    • HENKEL KOMMANDITGESELLSCHAFT AUF AKTIENFÖRSTER, ThomasCLAAS, MarcusKÜHN, AxelWACHTER, RolfWADLE, Armin
    • HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
    • A61K07/00
    • A61K8/062A61K8/375A61K8/86A61K2800/21A61Q19/00
    • Finely dispersed oil-in-water emulsions with a long-term stability, based on oil mixtures containing an organic cosmetic active agent can be obtained if (A) an oil body with (B) 0.5 to 30 wt %. of a non-ionic emulsifier with a hydrophile-lipophile balance of 10 to 18 and (C) or 0.1 to 30 wt % of a co-emulsifier from the group of fatty alcohols with 12 to 22 atoms or the partial esters of polyoles with 3 to 6 C atoms with fatty acids with 12 to 22 atoms and (D) an organic cosmetic active agent selected from the group of deodorizing agents, perfume oils and light-protective factors, provided that i) the sum of components (A) and (D) amounts to 10 to 90 wt % and ii) the proportion of the component (D) amounts to 5 to 100 wt % in relation to the oil body (A), is emulsified in the presence of 8 to 85 wt % of water at a temperature above the melting point of the mixture of components (A) to (D) and the emulsion is heated to a temperature within or above the phase inversion temperature range, or the emulsion is produced at this temperature, after which it is cooled to a temperature below said phase inversion temperature range and possibly further diluted with water.
    • 细分散的和长期稳定的油包水基上含有有机化妆品活性物质油性混合物乳剂可以通过用(B)0.5〜30重量的非离子型乳化剂的%的具有反应(A)的油体来获得 的HLB值为10〜18,(C)0或0.1至30重量从具有12至22个碳原子或含有3至6个C多元醇的偏酯的组中的脂肪醇的辅助乳化剂的% 与具有脂肪酸碳原子数为12〜22,和(D),其选自除臭剂活性成分,芳香油和防晒因子组成的组中的有机化妆品活性成分,条件原子数ⅰ)组分的总和(a)和(D) 10至90重量%,和ii)组分(D)范围为5至100重量%的比例 - 相对于所述油体(A) - 是,在8存在于85重量%的水 在(a)中乳化,以(D)的组分的混合物的熔点以上的温度和Emulsio n是加热到内或高于相转变温度范围内的温度 - 或乳液在该温度下制备的 - 然后将乳液冷却至低于相转变温度的温度范围内并且任选地与水进一步稀释。