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1. 发明申请

WO2010121130A2 MOLECULAR DELIVERY WITH NANOWIRES 审中-公开
标题翻译：与纳米级分子递送
公开(公告)号：WO2010121130A2
公开(公告)日：2010-10-21
申请号：PCT/US2010031392
申请日：2010-04-16
申请人： HARVARD COLLEGE , PARK HONGKUN , YANG EUNGYEONG , SHALEK ALEX , LEE JINSEOK , ROBINSON JACOB , SUTTON AMY , YOON MYUNG-HAN , JORGOLLI MARSELA
发明人： PARK HONGKUN , YANG EUNGYEONG , SHALEK ALEX , LEE JINSEOK , ROBINSON JACOB , SUTTON AMY , YOON MYUNG-HAN , JORGOLLI MARSELA
IPC分类号： H04W40/00
CPC分类号： C12N15/89 , C12N5/0075 , C12N2533/00 , C12N2535/00 , C12Q1/68 , G01N33/5008 , G01N33/5047 , G01N33/54353
摘要： A molecular delivery system including a plurality of nanowires (e.g., Si NWs), each of the nanowires having a surface layer formed of a silicon-containing material and a covalently bound linker (e.g., silane linker) attached to the surface layer, and optionally including a substrate to which the nanowires are adhered or a molecule to be delivered attached to the linker. Also disclosed is a method of delivering into a cell an exogenous molecule.
摘要翻译：包括多个纳米线（例如，Si NW）的分子递送系统，每个纳米线具有由含硅材料形成的表面层和附着到表面层的共价结合的接头（例如，硅烷接头），以及任选地包括粘附有纳米线的基底或要连接到连接体上的分子。还公开了向细胞递送外源性分子的方法。

2. 发明申请

WO2012051295A3 SYSTEM FOR EXTRACTING RESPIRATORY RATES FROM A PULSE OXIMETER 审中-公开
标题翻译：从脉搏血氧仪中提取呼吸速率的系统
公开(公告)号：WO2012051295A3
公开(公告)日：2012-07-19
申请号：PCT/US2011055961
申请日：2011-10-12
申请人： WORCESTER POLYTECH INST , CHON KI H , LEE JINSEOK
发明人： CHON KI H , LEE JINSEOK
IPC分类号： A61B5/08 , A61B5/1455
CPC分类号： A61B5/0816 , A61B5/14551 , A61B5/725
摘要： Accurate AR method for extracting respiratory rates directly from a pulse oximeter and accurate methods of extracting respiratory rates directly from a pulse oximeter under low signal-to-noise ratio (SNR) conditions.
摘要翻译：准确的AR方法直接从脉搏血氧仪提取呼吸频率，以及在低信噪比（SNR）条件下直接从脉搏血氧计提取呼吸频率的准确方法。

3. 发明申请

WO2012051320A3 MOTION AND NOISE ARTIFACT DETECTION FOR ECG DATA 审中-公开
标题翻译：心电数据运动和噪声检测
公开(公告)号：WO2012051320A3
公开(公告)日：2012-06-07
申请号：PCT/US2011055989
申请日：2011-10-12
申请人： WORCESTER POLYTECH INST , CHON KI H , LEE JINSEOK
发明人： CHON KI H , LEE JINSEOK
IPC分类号： A61B5/0402 , A61B5/0432
CPC分类号： A61B5/7207 , A61B5/04012 , A61B5/0404 , A61B5/0432 , A61B5/0456
摘要： Technologies are provided herein for real-time detection of motion and noise (MN) artifacts in electrocardiogram signals recorded by electrocardiography devices. Specifically, the present disclosure provides techniques for increasing the accuracy of identifying paroxysmal atrial fibrillation (AF) rhythms, which are often measured via such devices. According to aspects of the present disclosure, a method for detecting MN artifacts in an electrocardiogram (ECG) recording includes receiving an ECG segment and decomposing the received ECG segment into a sum of intrinsic mode functions. The intrinsic mode functions associated with MN artifacts present within the ECG segment are then isolated. The method further includes determining randomness and variability characteristic values associated with the isolated intrinsic mode functions and comparing the randomness and variability characteristic values to threshold randomness and variability characteristic values. If the randomness and variability characteristic values exceed the threshold characteristic values, the ECG signal is determined to include MN artifacts.
摘要翻译：本文提供的技术用于实时检测由心电图仪器记录的心电图信号中的运动和噪声（MN）伪影。具体地，本公开提供了用于增加识别阵发性心房颤动（AF）节律的准确性的技术，其经常通过这样的装置测量。根据本公开的方面，用于检测心电图（ECG）记录中的MN伪像的方法包括接收ECG片段并将接收到的ECG片段分解为固有模式功能的总和。然后隔离与ECG段内存在的MN伪影相关联的固有模式功能。该方法还包括确定与分离的固有模式函数相关联的随机性和可变性特征值，并将随机性和可变性特征值与阈值随机性和可变性特征值进行比较。如果随机性和变异性特征值超过阈值特征值，则确定ECG信号包括MN伪像。

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