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1. 发明申请

WO2009076961A1 4-[2,3-DIFLUORO-6-(2-FLUORO-4-METHYL-PHENYLSULFANYL)-PHENYL]-PIPERIDINE 审中-公开
标题翻译： 4- [2,3-二氟-6-（2-氟-4-甲基 - 苯基硫基） - 苯基] - 哌啶
公开(公告)号：WO2009076961A1
公开(公告)日：2009-06-25
申请号：PCT/DK2008/050301
申请日：2008-12-11
申请人： H. LUNDBECK A/S , BANG-ANDERSEN, Benny , JØRGENSEN, Morten , FALDT, André , ANDERSON, Neil , STENSBØL, Tine, Bryan
发明人： BANG-ANDERSEN, Benny , JØRGENSEN, Morten , FALDT, André , ANDERSON, Neil , STENSBØL, Tine, Bryan
IPC分类号： C07D211/20 , A61K31/451 , A61P25/00
CPC分类号： C07D211/20
摘要： The compound 4-[2,3-Difluoro-6-(2-fluoro-4-methyl-phenylsulfanyl)-phenyl]-piperidine according to the structure (formula I), and pharmaceutically acceptable salts thereof are provided for the treatment of CNS related disorders, such as : depressive disorder, dysthymic disorder; mood disorder due to a general medical condition; atypical depression; seasonal affective disorder; melancholia; treatment resistant depression; partial responders; depression associated with bipolar disorder, pain, Alzheimer's disease, psychosis, Parkinson's disease, Lewy body disease, Huntington's disease, multiple sclerosis or anxiety; general anxiety disorder, social anxiety disorder, panic attacks; phobia; social phobia, obsessive compulsive disorder; post traumatic stress disorder, acute stress; ADHD; and pain.
摘要翻译：根据结构（式I）的化合物4- [2,3-二氟-6-（2-氟-4-甲基 - 苯硫基） - 苯基] - 哌啶及其药学上可接受的盐被用于治疗CNS 相关疾病，如：抑郁障碍，精神抑郁障碍; 一般情况下情绪障碍; 非典型抑郁症季节性情绪失调; 忧郁症; 耐药抑郁症; 部分回应者与双相障碍，疼痛，阿尔茨海默病，精神病，帕金森病，路易体病，亨廷顿病，多发性硬化或焦虑有关的抑郁症; 一般焦虑症，社会焦虑症，惊恐发作; 恐怖症; 社交恐惧症，强迫症; 创伤后应激障碍，急性应激; 多动症; 和痛苦。

2. 发明申请

WO2009112541A2 [2-(6-FLOURO-1H-INDOL-3-YLSULFANYL)BENZYL]METHYL AMINE FOR THE TREATMENT OF AFFECTIVE DISORDERS 审中-公开
标题翻译： [2-（6-氟 - 1
公开(公告)号：WO2009112541A2
公开(公告)日：2009-09-17
申请号：PCT/EP2009/052899
申请日：2009-03-12
申请人： H. LUNDBECK A/S , SPROUSE, Jeffrey, Scott , SØBY, Karina, Krøjer , ANDERSON, Neil
发明人： SPROUSE, Jeffrey, Scott , SØBY, Karina, Krøjer , ANDERSON, Neil
IPC分类号： A61K31/404 , A61P25/00 , A61P25/18 , A61P25/22 , A61P25/24
CPC分类号： A61K31/404
摘要： [2-(6-fluoro-1 H -indol-3-ylsulfanyl)benzyl]methyl amine and pharmaceutically acceptable salts thereof is provided for the treatment of CNS disorders.
摘要翻译： [2-（6-氟-1H-吲哚-3-基硫烷基）苄基]甲胺及其药学上可接受的盐被用于治疗CNS疾病。

3. 发明公开

EP2231599A1 4-[2,3-DIFLUORO-6-(2-FLUORO-4-METHYL-PHENYLSULFANYL)-PHENYL]-PIPERIDINE 审中-公开
标题翻译： 4- [2,3-二氟-6-（2-氟-4-甲基 - 苯基硫基） - 苯基] - 哌啶
公开(公告)号：EP2231599A1
公开(公告)日：2010-09-29
申请号：EP08861621.4
申请日：2008-12-11
申请人： H. Lundbeck A/S
发明人： BANG-ANDERSEN, Benny , JØRGENSEN, Morten , FALDT, André , ANDERSON, Neil , STENSBØL, Tine, Bryan
IPC分类号： C07D211/20 , A61K31/451 , A61P25/00
CPC分类号： C07D211/20
摘要： The compound 4-[2,3-Difluoro-6-(2-fluoro-4-methyl-phenylsulfanyl)-phenyl]-piperidine according to the structure (formula I), and pharmaceutically acceptable salts thereof are provided for the treatment of CNS related disorders, such as : depressive disorder, dysthymic disorder; mood disorder due to a general medical condition; atypical depression; seasonal affective disorder; melancholia; treatment resistant depression; partial responders; depression associated with bipolar disorder, pain, Alzheimer's disease, psychosis, Parkinson's disease, Lewy body disease, Huntington's disease, multiple sclerosis or anxiety; general anxiety disorder, social anxiety disorder, panic attacks; phobia; social phobia, obsessive compulsive disorder; post traumatic stress disorder, acute stress; ADHD; and pain.

4. 发明公开

EP2074091A1 [2-(6-FLOURO-1H-INDOL-3-YLSULFANYL)BENZYL]METHYL AMINE FOR THE TREATMENT OF AFFECTIVE DISORDERS 有权
标题翻译： [2-（6-氟-1H-吲哚-3-基硫烷基）苄基]甲胺用于治疗情感障碍
公开(公告)号：EP2074091A1
公开(公告)日：2009-07-01
申请号：EP07817817.5
申请日：2007-09-27
申请人： H. LUNDBECK A/S
发明人： KEHLER, Jan , JUHL, Karsten , ANDERSON, Neil
IPC分类号： C07D209/30 , A61K31/404 , A61P13/02 , A61P21/00 , A61P25/16 , A61P25/18
CPC分类号： C07D209/30
摘要： [2-(6-fluoro-lH-indol-3-ylsulfanyl)benzyl]methyl amine and pharmaceutically acceptable salts thereof, provided it is not the free base in a non-crystalline form are provided for the treatment of affective disorders.

5. 发明授权

EP2074091B1 [2-(6-FLOURO-1H-INDOL-3-YLSULFANYL)BENZYL]METHYL AMINE FOR THE TREATMENT OF AFFECTIVE DISORDERS 有权
标题翻译： [2-（6-氟-1H-吲哚-3-基硫烷基）苄基]甲胺用于治疗情感障碍
公开(公告)号：EP2074091B1
公开(公告)日：2015-01-07
申请号：EP07817817.5
申请日：2007-09-27
申请人： H. Lundbeck A/S
发明人： KEHLER, Jan , JUHL, Karsten , ANDERSON, Neil
IPC分类号： C07D209/30 , A61K31/404 , A61P13/02 , A61P21/00 , A61P25/16 , A61P25/18
CPC分类号： C07D209/30

6. 发明申请

WO2007104109A1 AN ELECTRODE SHEATH FOR A CATHETER 审中-公开
标题翻译：电导管的电极
公开(公告)号：WO2007104109A1
公开(公告)日：2007-09-20
申请号：PCT/AU2007/000325
申请日：2007-03-15
申请人： CATHRX LTD , ANDERSON, Neil
发明人： ANDERSON, Neil
IPC分类号： A61N1/06 , A61N1/05
CPC分类号： A61N1/06 , A61B18/1492 , A61B2018/00577 , A61B2018/00642
摘要： An electrode sheath (10) for a catheter includes an elongate body member (12) having a proximal end and a distal end (14) and which defines a lumen (16) extending from the proximal end to the distal end (14). A part (18) of a periphery of the body member (12 ) is substantially flat to form a longitudinally extending planar receiving zone (20) for electrical conductors (32). An electrical conductor arrangement (22) is received in the receiving zone (20) and extends towards the distal end (14) of the body member (12). At least one substantially planar electrode (24) is arranged distally on the body member (12), the at least one electrode (24) overlying a distal region of the electrical conductor arrangement (22) and being in electrical contact with at least some of the conductors (32) of the electrical conductor arrangement (22).
摘要翻译：用于导管的电极护套（10）包括具有近端和远端（14）并且限定从近端延伸到远端（14）的内腔（16）的细长本体构件（12）。主体构件（12）的周边的部分（18）基本上是平的，以形成用于电导体（32）的纵向延伸的平面接收区（20）。电导体装置（22）被容纳在接收区域（20）中并且朝向主体构件（12）的远端（14）延伸。至少一个基本上平面的电极（24）远离地布置在主体构件（12）上，所述至少一个电极（24）覆盖在电导体装置（22）的远侧区域上并且与至少一些电导体装置（22）的导体（32）。

7. 发明申请

WO2012104574A3 DOWNHOLE PRESSURE RELIEF APPARATUS 审中-公开
公开(公告)号：WO2012104574A3
公开(公告)日：2012-08-09
申请号：PCT/GB2012/000026
申请日：2012-01-13
申请人： TENDEKA B.V. , ANDERSON, Neil , PITMAN, Malcolm
发明人： ANDERSON, Neil , PITMAN, Malcolm
IPC分类号： E21B34/06 , E21B41/00 , E21B47/06
摘要： A downhole pressure relief apparatus (10) comprises a tubular member (18) configured to be located within a wellbore (12) to at least partially define a wellbore annulus (26), wherein the annulus (26) is subject to varying fluid pressure, and a chamber (36) associated with the tubular member (18). A valve arrangement (38) associated with the chamber (36) is provided and is configurable from a closed state to an open state in response to a pressure event, wherein, in use, in the closed state the chamber (36) is isolated from the wellbore annulus (26), and in the open state fluid (28) is permitted to flow into the chamber (36) from the wellbore annulus (26) to relieve pressure within said annulus.

8. 发明申请

WO2002094581A1 IMAGE TRANSFER APPARATUS AND METHOD 审中-公开
标题翻译：图像传输装置和方法
公开(公告)号：WO2002094581A1
公开(公告)日：2002-11-28
申请号：PCT/GB2002/002394
申请日：2002-05-22
申请人： MICYTE LIMITED , SHAW, Robert, Adrian , ANDERSON, Neil , HERRING, Peter, Richard , HOWELL, Dr. Jeffery Michael
发明人： SHAW, Robert, Adrian , ANDERSON, Neil , HERRING, Peter, Richard , HOWELL, Dr. Jeffery Michael
IPC分类号： B44C1/16
CPC分类号： B44C1/1712
摘要： Image transfer apparatus (10) transfers an image from a printed transfer sheet (200) into a clear lacquer coating which has been previously applied to a component (100). The image transfer is effected by the application of heat and pressure to the transfer sheet (200) and component (100), by means of a resilient, heated pad (46) into which the transfer sheet and component are urged. The pad (46) is heated by means of an aluminium heater block (41) and the transfer sheet (200) and component (100) are urged into engagement with the pad (46) by a lifting mechanism (20). The component handling section (60) comprises a drawer (61) on which is mounted a transfer sheet support means (63). The component support means (80,86) is slidably mounted within the transfer sheet support means. When the drawer (61) is closed, the lifting mechanism (20) raises the component (100) and transfer sheet (200) to a pre-conditioning position close to the heated pad, so that the transfer sheet is softened, and then further raises the component (100) relative to the transfer sheet, pushing the component into engagement with the heated pad, through the transfer sheet (200).
摘要翻译：图像转印装置（10）将图像从印刷的转印纸（200）转印到先前施加到部件（100）上的透明漆层中。图像转印通过对转印片（200）和组分（100）施加热和压力，借助于弹性的加热垫（46）进行，转印片和组分被推向该垫中。垫（46）通过铝加热器块（41）加热，转印片（200）和部件（100）被提升机构（20）推动与垫（46）接合。部件处理部分（60）包括一个抽屉（61），转印纸支撑装置（63）安装在该抽屉上。部件支撑装置（80,86）可滑动地安装在转印纸支承装置内。当抽屉（61）关闭时，提升机构（20）将部件（100）和转印纸（200）升高到靠近加热垫的预调节位置，使得转印纸软化，然后进一步通过转印纸（200）将组件（100）相对于转印纸升起，推动元件与加热垫接合。

9. 发明申请

WO2012150453A1 DEVICE AND METHOD FOR NON-INVASIVE COLLECTION OF COLORECTAL MUCOCELLULAR LAYER AND DISEASE DETECTION 审中-公开
标题翻译：非侵入性收集色素细胞层和疾病检测的装置和方法
公开(公告)号：WO2012150453A1
公开(公告)日：2012-11-08
申请号：PCT/GB2012/050964
申请日：2012-05-03
申请人： DIAGNODUS LIMITED , LOKTIONOV, Alexandre , BANDALETOVA, Tatiana , ANDERSON, Neil
发明人： LOKTIONOV, Alexandre , BANDALETOVA, Tatiana , ANDERSON, Neil
IPC分类号： G01N33/50 , G01N33/574
CPC分类号： G01N1/30 , G01N33/5044 , G01N33/6893 , G01N2800/065
摘要： The present invention relates to a device and a method for collecting a sample of colorectal mucocellular layer excreted immediately following the natural act of defaecation from the surface of the anal area of a human subject, and preservation and analysis of the collected sample for detecting diagnostically informative disease biomarkers.
摘要翻译：本发明涉及一种装置和方法，用于收集自从人类肛门区域的表面自然脱失后立即排泄的结肠直肠粘膜细胞层的样品，以及用于检测诊断信息的收集样品的保存和分析疾病生物标志物。

10. 发明申请

WO2009154734A2 METHOD OF CONTROLLING EVAPORATION OF A FLUID IN AN ARTICLE 审中-公开
标题翻译：控制流体中物质蒸发的方法
公开(公告)号：WO2009154734A2
公开(公告)日：2009-12-23
申请号：PCT/US2009/003596
申请日：2009-06-16
申请人： CENTURY, INC. , SCHUETZ, James, E. , MCCULLOUGH, Thomas, W. , ANDERSON, Neil , LACOSSE, Justin , WOOD, Thomas, D.
发明人： SCHUETZ, James, E. , MCCULLOUGH, Thomas, W. , ANDERSON, Neil , LACOSSE, Justin , WOOD, Thomas, D.
IPC分类号： F26B9/00
CPC分类号： F26B9/006 , B29C47/0004 , B29C47/0021 , B29C47/38 , B29C47/404 , B29C47/42 , B29K2105/06 , C04B2235/3418 , C04B2235/3826 , C04B2235/5228 , C04B2235/5248 , C04B2235/526 , C04B2235/5264 , C04B2235/5268 , C04B2235/5296 , C04B2235/5436 , C04B2235/6021 , C04B2235/6562 , C04B2235/77
摘要： A method of controlling evaporation of a fluid, such as water, in an article includes the step of encapsulating the article with a film such that the fluid is prevented from evaporating from the article. The method further includes the step of heating the article encapsulated with the film to a first desired temperature for a first period of time while preventing the fluid from evaporating from the article. The method also includes the step of removing the film from the article after heating the article to the first desired temperature for the first period of time and, after the step of removing the film the article, the method includes the step of further heating the article to a second desired temperature for a second period of time while the fluid freely evaporates from the article.
摘要翻译：控制制品中诸如水的流体的蒸发的方法包括用膜封装制品以防止流体从制品中蒸发的步骤。该方法还包括以下步骤：将封装有薄膜的制品在第一期间内加热至第一期望温度，同时防止流体从制品中蒸发。该方法还包括在将制品加热至第一期望温度第一段时间之后将物品从制品中除去的步骤，并且在除去薄膜物品的步骤之后，该方法包括以下步骤：达到第二期望温度持续第二时间段，同时流体从制品自由蒸发。

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