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1. 发明申请

US20120220688A1 Phosphine-Containing Hydrogel Contact Lenses 有权
标题翻译：含磷的水凝胶隐形眼镜
公开(公告)号：US20120220688A1
公开(公告)日：2012-08-30
申请号：US13404028
申请日：2012-02-24
申请人： Guigui Wang , Yun Zhang , Yuwen Liu , Ye Hong , Charlie Chen , Peter Zhu
发明人： Guigui Wang , Yun Zhang , Yuwen Liu , Ye Hong , Charlie Chen , Peter Zhu
IPC分类号： G02B1/04 , G02C7/04 , B65D85/00
CPC分类号： G02B1/043 , A45C11/005 , B65D81/22 , C08L83/04
摘要： Hydrogel contact lenses that are derived from a polymerizable composition including at least one hydrophilic monomer and at least one phosphine-containing component are described. The hydrogel of the contact lenses can be a silicone hydrogel or a non-silicone hydrogel. Use of polymerizable compositions comprising a phosphine-containing component can be cured under both inert and air atmospheres, and can be used to form hydrogel contact lenses having improved shape retention properties, having improved resistance to discoloration. Batches of hydrogel contact lenses and methods of making hydrogel contact lenses are also described.
摘要翻译：描述了衍生自包含至少一种亲水性单体和至少一种含膦组分的可聚合组合物的水凝胶隐形眼镜。隐形眼镜的水凝胶可以是硅酮水凝胶或非硅氧水凝胶。包含含膦组分的可聚合组合物的使用可以在惰性和空气气氛下固化，并且可用于形成具有改善的变色保持性能的具有改进的抗变色性的水凝胶隐形眼镜。还描述了水凝胶隐形眼镜的批次和制备水凝胶隐形眼镜的方法。

2. 发明授权

US08642677B2 Phosphine-containing hydrogel contact lenses 有权
标题翻译：含磷的水凝胶隐形眼镜
公开(公告)号：US08642677B2
公开(公告)日：2014-02-04
申请号：US13404028
申请日：2012-02-24
申请人： Guigui Wang , Yun Zhang , Yuwen Liu , Ye Hong , Charlie Chen , Peter Zhu
发明人： Guigui Wang , Yun Zhang , Yuwen Liu , Ye Hong , Charlie Chen , Peter Zhu
IPC分类号： C08F8/00
CPC分类号： G02B1/043 , A45C11/005 , B65D81/22 , C08L83/04
摘要： Hydrogel contact lenses that are derived from a polymerizable composition including at least one hydrophilic monomer and at least one phosphine-containing component are described. The hydrogel of the contact lenses can be a silicone hydrogel or a non-silicone hydrogel. Use of polymerizable compositions comprising a phosphine-containing component can be cured under both inert and air atmospheres, and can be used to form hydrogel contact lenses having improved shape retention properties, having improved resistance to discoloration. Batches of hydrogel contact lenses and methods of making hydrogel contact lenses are also described.
摘要翻译：描述了衍生自包含至少一种亲水性单体和至少一种含膦组分的可聚合组合物的水凝胶隐形眼镜。隐形眼镜的水凝胶可以是硅酮水凝胶或非硅氧水凝胶。包含含膦组分的可聚合组合物的使用可以在惰性和空气气氛下固化，并且可用于形成具有改善的变色保持性能的具有改进的抗变色性的水凝胶隐形眼镜。还描述了水凝胶隐形眼镜的批次和制备水凝胶隐形眼镜的方法。

3. 发明申请

US20120194779A1 Materials For Use In Ophthalmic Applications And Methods 有权
标题翻译：用于眼科应用和方法的材料
公开(公告)号：US20120194779A1
公开(公告)日：2012-08-02
申请号：US13395134
申请日：2010-09-21
申请人： Yun Zhang , Charlie Chen , Peter Zhu , Ying Ye , Hongjin Qiu
发明人： Yun Zhang , Charlie Chen , Peter Zhu , Ying Ye , Hongjin Qiu
IPC分类号： G02C7/04 , B05D5/06
CPC分类号： C08J7/16
摘要： A lens body comprising at least one form of boronic acid, boronic ester or boronic anhydride is provided. The lens body is contacted with a solution comprising at least one form of TRIS. A contact lens package including the contact lens, and methods of producing and using the contact lens, are also provided.
摘要翻译：提供了包含至少一种形式的硼酸，硼酸酯或硼酸酐的透镜体。透镜体与包含至少一种形式的TRIS的溶液接触。还提供了包括隐形眼镜的隐形眼镜包，以及制造和使用隐形眼镜的方法。

4. 发明授权

US08410190B2 Wettable hydrogel materials for use in ophthalmic applications and methods 有权
标题翻译：用于眼科应用和方法的可湿性水凝胶材料
公开(公告)号：US08410190B2
公开(公告)日：2013-04-02
申请号：US13146414
申请日：2010-09-21
申请人： Peter Zhu , Ying Ye , Yun Zhang , Charlie Chen
发明人： Peter Zhu , Ying Ye , Yun Zhang , Charlie Chen
IPC分类号： G02B1/04
CPC分类号： C08J7/16
摘要： A contact lens is provided that has extended and rechargeable wettability. The contact lens includes a lens body that is a reaction product of a polymerizable composition. A first polyhydric alcohol having a 1,2 diol or 1,3 diol moiety is present on a lens surface of the lens body. A contact lens package including the contact lens, and methods of producing and using the contact lens, are also provided.
摘要翻译：提供了一种具有延长和充分润湿性的隐形眼镜。隐形眼镜包括作为可聚合组合物的反应产物的透镜体。具有1,2-二醇或1,3-二醇部分的第一多元醇存在于透镜体的透镜表面上。还提供了包括隐形眼镜的隐形眼镜包，以及制造和使用隐形眼镜的方法。

5. 发明授权

US08646907B2 Materials for use in ophthalmic applications and methods 有权
标题翻译：用于眼科应用的材料和方法
公开(公告)号：US08646907B2
公开(公告)日：2014-02-11
申请号：US13395134
申请日：2010-09-21
申请人： Yun Zhang , Charlie Chen , Peter Zhu , Ying Ye , Hongjin Qiu
发明人： Yun Zhang , Charlie Chen , Peter Zhu , Ying Ye , Hongjin Qiu
IPC分类号： G02C7/04
CPC分类号： C08J7/16
摘要： A lens body comprising at least one form of boronic acid, boronic ester or boronic anhydride is provided. The lens body is contacted with a solution comprising at least one form of TRIS. A contact lens package including the contact lens, and methods of producing and using the contact lens, are also provided.
摘要翻译：提供了包含至少一种形式的硼酸，硼酸酯或硼酸酐的透镜体。透镜体与包含至少一种形式的TRIS的溶液接触。还提供了包括隐形眼镜的隐形眼镜包，以及制造和使用隐形眼镜的方法。

6. 发明申请

US20120172486A1 Wettable Hydrogel Materials For Use In Ophthalmic Applications And Methods 有权
标题翻译：可湿性水凝胶材料用于眼科应用和方法
公开(公告)号：US20120172486A1
公开(公告)日：2012-07-05
申请号：US13146414
申请日：2010-09-21
申请人： Peter Zhu , Ying Ye , Yun Zhang , Charlie Chen
发明人： Peter Zhu , Ying Ye , Yun Zhang , Charlie Chen
IPC分类号： C08L43/00 , B29D11/00
CPC分类号： C08J7/16
摘要： A contact lens is provided that has extended and rechargeable wettability. The contact lens includes a lens body that is a reaction product of a polymerizable composition. A first polyhydric alcohol having a 1,2 diol or 1,3 diol moiety is present on a lens surface of the lens body. A contact lens package including the contact lens, and methods of producing and using the contact lens, are also provided.
摘要翻译：提供了一种具有延长和充分润湿性的隐形眼镜。隐形眼镜包括作为可聚合组合物的反应产物的透镜体。具有1,2-二醇或1,3-二醇部分的第一多元醇存在于透镜体的透镜表面上。还提供了包括隐形眼镜的隐形眼镜包，以及制造和使用隐形眼镜的方法。

7. 发明申请

US20050238732A1 Carbonated germicide with pressure control 审中-公开
标题翻译：碳酸化杀菌剂与压力控制
公开(公告)号：US20050238732A1
公开(公告)日：2005-10-27
申请号：US11001249
申请日：2004-11-30
申请人： Kaitao Lu , Peter Zhu
发明人： Kaitao Lu , Peter Zhu
IPC分类号： A01N25/02 , A01N35/02 , A01N35/04 , A01N59/00 , A01N59/08 , A01N59/10 , A01N59/12 , A61L2/18 , B65D83/14 , A61K31/11 , A61K33/00
CPC分类号： A61L2/186 , A01N25/22 , A01N35/02 , A01N35/04 , A61L2/22 , A61L2/24 , A61L9/00 , A61L9/14 , A61L9/145 , A61L2202/122 , A61L2202/18 , A01N59/08 , A01N59/04 , A01N33/12 , A01N59/00 , A01N59/02 , A01N59/10 , A01N59/12 , A01N2300/00
摘要： Disclosed herein are methods of sealing germicidal bicarbonate solutions in containers. In one aspect, a method may include introducing water, bicarbonate, and a germicide that is more stable at a pH of 7 than at a pH of 8 into a container, replacing at least a portion of a gas in the container with carbon dioxide, and sealing the container after said introducing the water, the bicarbonate, and the germicide, into the container, and after said replacing the gas. Sealed containers having the germicidal bicarbonate solutions are also disclosed.
摘要翻译：本文公开了在容器中密封杀菌碳酸氢盐溶液的方法。在一个方面，一种方法可以包括将水，碳酸氢盐和在pH8以上比pH8更稳定的杀菌剂引入容器中，用二氧化碳代替容器中至少一部分气体，并且在将水，碳酸氢盐和杀菌剂引入容器之后，以及在更换气体之后密封容器。还公开了具有杀菌碳酸氢盐溶液的密封容器。

8. 发明申请

US20060228801A1 Integator system and method for rapidly determining effectiveness of a germicidal treatment 审中-公开
标题翻译：用于快速确定杀菌处理有效性的整数系统和方法
公开(公告)号：US20060228801A1
公开(公告)日：2006-10-12
申请号：US11093529
申请日：2005-03-30
申请人： Ben Fryer , Peter Zhu
发明人： Ben Fryer , Peter Zhu
IPC分类号： G01N21/64
CPC分类号： G01N21/31 , A61L2/28 , C12Q1/22 , G01N31/226 , Y10T436/101666 , Y10T436/13
摘要： The effectiveness of an oxidative sterilization process is determined by exposing a substrate having a known amount of a primary amine or aldehyde indicator chemical to an oxidative germicide. The oxidative germicide reacts with the indicator chemical. The amount of indicator chemical remaining after exposure to the germicide is determined by reacting the indicator chemical with a dye precursor chemical to form a colored product. The amount of indicator chemical remaining on the substrate is determined from the intensity of the color of the colored product. The amount of indicator chemical remaining on the substrate is a measure of the effectiveness of the germicidal treatment. The dye precursor is an aldehyde when the indicator chemical is a primary amine and a primary amine when the indicator chemical is an aldehyde. An integrator for determining the effectiveness of the germicidal process includes a substrate and an indicator chemical, where the indicator chemical is a primary amine or an aldehyde.
摘要翻译：通过将具有已知量的伯胺或醛指示剂化学品的底物暴露于氧化性杀菌剂来确定氧化灭菌过程的有效性。氧化杀菌剂与指示剂化学反应。通过使指示剂化学品与染料前体化学品反应形成有色产物来确定暴露于杀菌剂之后剩余的指示剂化学物质的量。基材上剩余的指示剂化学物质的量由着色产物的颜色强度确定。残留在底物上的指示剂化学品的量是杀菌处理的有效性的量度。当指示剂化学品为醛时，指示剂化学品为伯胺和伯胺时，染料前体是醛。用于确定杀菌过程的有效性的积分器包括底物和指示剂化学品，其中指示剂化学品是伯胺或醛。

9. 发明申请

US20060219261A1 Monitoring of cleaning process 有权
公开(公告)号：US20060219261A1
公开(公告)日：2006-10-05
申请号：US11095251
申请日：2005-03-31
申请人： Szu-Min Lin , Paul Jacobs , Jenn-Hann Wang , Robert Platt , Peter Zhu
发明人： Szu-Min Lin , Paul Jacobs , Jenn-Hann Wang , Robert Platt , Peter Zhu
IPC分类号： B08B7/04 , B08B3/00
CPC分类号： A61L2/186 , A61B1/00057 , A61B1/123 , A61B90/70 , A61B2090/701 , A61B2090/702 , A61L2/183 , A61L2/28 , A61L2202/122 , A61L2202/17 , A61L2202/24 , G01N31/22
摘要： A method for monitoring a cleaning process for a medical instrument, includes the steps of placing the instrument in a cleaning chamber; placing a soil standard in the cleaning chamber; cleaning the instrument and the soil standard with a cleaning solution; and detecting whether soil remains on said soil standard. The soil standard includes two substantially parallel substrates separated with two substantially equal thickness spacers, wherein a gap is formed between the two substrates with soil in the gap.

10. 发明申请

US20050107631A1 Non-hazardous oxidative neutralization of aldehydes 失效
标题翻译：醛的无害氧化中和
公开(公告)号：US20050107631A1
公开(公告)日：2005-05-19
申请号：US11013681
申请日：2004-12-16
申请人： Peter Zhu
发明人： Peter Zhu
IPC分类号： A62D3/00 , A62D3/36 , C07C51/16 , C07C51/235
CPC分类号： A62D3/36
摘要： Methods, compositions, and devices for alleviating the problems of toxic discharge of aldehydes present in waste streams are disclosed. The methods relate to forming neutralized aldehydes by treating aldehydes with oxidizing agents. The oxidizing agents offer a simple, effective, fast and inexpensive solution for treatment of toxic aldehydes prior to disposal into the environment.
摘要翻译：公开了用于减轻存在于废物流中的醛的有毒排放问题的方法，组合物和装置。该方法涉及通过用氧化剂处理醛形成中和的醛。氧化剂提供了一种简单，有效，快速和便宜的解决方案，用于处理有毒醛，然后再处置到环境中。

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