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    • 6. 发明授权
    • RF channel linking method and system
    • RF信道链接方法和系统
    • US07248836B2
    • 2007-07-24
    • US10261933
    • 2002-09-30
    • Ronald Taylor
    • Ronald Taylor
    • H04Q7/20H04B17/00
    • H04W52/50G07C9/00103G07C2009/00793
    • In an RF access control system, a method for establishing a reliable RF signal link between points of the RF access control system. A first RF signal from a first point of the system is transmitted to a second point of the system at a first RF power level that is below a second RF power level used during normal operation of the RF access control system. Once the second point acknowledges the RF signal from the first point, then a pre-determined number of RF packets are transmitted and received back and forth between the first point and the second point at the first RF power level. An RF packet error count is generated in response to the transmitting and receiving of the pre-determined number of RF packets. If this error count is below a certain threshold value, then an indication is provided to an installer of the RF access control system of an RF channel number to be used by the RF access control system during normal operation.
    • 在RF接入控制系统中,用于在RF接入控制系统的点之间建立可靠的RF信号链路的方法。 来自系统的第一点的第一RF信号以低于在RF接入控制系统的正常操作期间使用的第二RF功率电平的第一RF功率电平被发送到系统的第二点。 一旦第二点确认来自第一点的RF信号,则在第一RF功率电平下,在第一点和第二点之间来回发送和接收预定数量的RF分组。 响应于发送和接收预定数量的RF分组而产生RF分组错误计数。 如果该错误计数低于某个阈值,则在正常操作期间向RF接入控制系统使用的RF信道号的RF接入控制系统的安装者提供指示。
    • 10. 发明申请
    • Heteropolymer complexes and methods for their use
    • 杂聚物复合物及其使用方法
    • US20050221284A1
    • 2005-10-06
    • US10484374
    • 2002-07-17
    • Ronald TaylorMaria CraigChang Hahn
    • Ronald TaylorMaria CraigChang Hahn
    • A61K39/00A61K39/395A61K47/48A61P29/00A61P31/04A61P31/10A61P31/12A61P33/02A61P35/00C07K1/113C07K16/08C07K16/10C07K16/12C07K16/28C07K16/30C07K19/00C12P21/08C12Q1/70G01N33/569G01N33/86
    • C07K16/2896A61K47/6851A61K2039/505C07K16/08C07K16/1081C07K16/12C07K16/1214C07K16/1232C07K2317/31C07K2317/52C07K2317/55G01N33/569G01N33/86G01N2333/4716Y02A50/386Y02A50/403Y02A50/53
    • The present invention relates to an improved heteropolymer complex. The improved heteropolymer complex comprises a first monoclonal antibody specific for a C3b-like receptor (known as complement receptor (CR1) or CD35 in primates and Factor H in other mammals, e.g., dog, mouse, rat, pig, rabbit) site chemically crosslinked (covalently linked) to a second monoclonal antibody, in which the isotype of at least the second monoclonal antibody is the isotype having the highest affinity for the Fc receptor, e.g., in humans, IgG1 or IgG3. The present invention also relates to methods for immune clearance of an antigen in a mammal via the C3b-like receptor comprising administering to said mammal an improved heteropolymer complex of the invention. The present invention also relates to methods for treating or preventing viral infection or microbial infection in a mammal comprising administering to said mammal an improved heteropolymer complex of the invention. The present invention also relates to methods for treating or preventing septic shock in a mammal comprising administering to said mammal an improved heteropolymer complex of the invention. The present invention also relates to methods for treating cancer in a mammal comprising administering to said mammal an improved heteropolymer complex of the invention. The present invention further relates to pharmaceutical compositions for the treatment or prevention of viral infection, microbial infection, septic shock, and cancer comprising an improved heteropolymer complex of the invention.
    • 本发明涉及一种改进的异源聚合物复合物。 改进的杂合聚合物复合物包含对C3b样受体(称为补体受体(CR1))或灵长类动物中的CD35和其它哺乳动物(例如狗,小鼠,大鼠,猪,兔)中的因子H特异的第一单克隆抗体 (共价连接)第二单克隆抗体,其中至少第二单克隆抗体的同种型是对Fc受体具有最高亲和力的同种型,例如在人IgG1或IgG3中。 本发明还涉及通过C3b样受体免疫清除哺乳动物中抗原的方法,包括向所述哺乳动物施用改进的本发明的杂合聚合物复合物。 本发明还涉及用于治疗或预防哺乳动物的病毒感染或微生物感染的方法,其包括向所述哺乳动物施用改进的本发明的杂合聚合物复合物。 本发明还涉及用于治疗或预防哺乳动物感染性休克的方法,其包括向所述哺乳动物施用改进的本发明的杂合聚合物复合物。 本发明还涉及用于治疗哺乳动物癌症的方法,包括向所述哺乳动物施用改进的本发明的杂合聚合物复合物。 本发明还涉及用于治疗或预防病毒感染,微生物感染,败血性休克和包含本发明的改进的杂合聚合物复合物的癌症的药物组合物。