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1. 发明申请

US20060258036A1 Waveguide with reduced higher modes 审中-公开
标题翻译：降低模式的波导
公开(公告)号：US20060258036A1
公开(公告)日：2006-11-16
申请号：US11126791
申请日：2005-05-11
申请人： Gregory Moore , John Rahn
发明人： Gregory Moore , John Rahn
IPC分类号： H01L21/00
CPC分类号： G01C19/72
摘要： An apparatus in one example has an integrated optic component having at least a higher order mode energy and a lower order mode energy. The integrated optic component also has a portion with a predetermined configuration such that radiation divergence losses of the higher order mode energy being much larger than radiation divergence losses of the lower order mode energy.
摘要翻译：一个示例中的装置具有至少具有较高阶模式能量和较低阶模态能量的集成光学部件。集成光学部件还具有预定配置的部分，使得较高阶模式能量的辐射发散损耗远大于较低阶模式能量的辐射发散损耗。

2. 发明授权

US08544114B2 Exercise suit 有权
标题翻译：运动服
公开(公告)号：US08544114B2
公开(公告)日：2013-10-01
申请号：US13034240
申请日：2011-02-24
申请人： Dexter Williams , Derrick Johnson , Gregory Moore
发明人： Dexter Williams , Derrick Johnson , Gregory Moore
IPC分类号： A41D13/00
CPC分类号： A41D13/0015
摘要： An exercise suit which includes a resilient band extending through a guide pocket in a first direction along a pant leg or sleeve of the suit. The band engages a direction changing means near the end of the leg or sleeve and at least a portion of the band extends there beyond in a second direction. A free end of the band is releasably engaged with a tension adjustment mechanism provided on the exterior of the leg or sleeve a distance away from the direction changing means. The wearer adjusts the tension in the band by moving a length of the band through the direction changing means and repositioning the free end on the tension adjustment mechanism. A cover is removably disposed over the tension adjustment mechanism to prevent accidental dislodgement of the free end of the band.
摘要翻译：一种运动服，其包括沿着衣服的裤腿或套筒沿第一方向延伸穿过引导口的弹性带。带子接近靠近腿或套筒端部的方向改变装置，并且带的至少一部分在第二方向上延伸到那里。带的自由端可释放地与设置在腿部或套筒的外部上的距离方向改变装置一定距离的张力调节机构接合。穿着者通过使方向改变装置移动带的长度并将自由端重新定位在张力调节机构上来调节带中的张力。盖可拆卸地设置在张力调节机构上以防止带的自由端的意外移动。

3. 发明授权

US08268305B1 Method and compositions to reduce serum levels of triacylglycerides in human beings using a fungal lipase 有权
标题翻译：使用真菌脂肪酶降低人的三酰基甘油酯血清水平的方法和组合物
公开(公告)号：US08268305B1
公开(公告)日：2012-09-18
申请号：US13244131
申请日：2011-09-23
申请人： Christopher Schuler , Edward Schuler , Christopher S. Penet , Gregory Moore , Kelly Gregory
发明人： Christopher Schuler , Edward Schuler , Christopher S. Penet , Gregory Moore , Kelly Gregory
IPC分类号： A61K38/46 , A61K38/48 , A61K38/54 , A61K47/00
CPC分类号： A61K38/465 , A61K9/4866
摘要： The invention relates to methods and compositions for reducing serum levels of triacylglycerides in human subjects. In particular, the invention relates to the oral administration of an effective amount of a fungal lipase formulation, to a human subject having borderline-high or high serum levels of triacylglycerides, for a time period sufficient to reduce serum triacylglyceride levels.
摘要翻译：本发明涉及用于降低人受试者中三酰基甘油酯的血清水平的方法和组合物。特别地，本发明涉及有效量的真菌脂肪酶制剂对具有高端或高血清三酰甘油酯水平的人类受试者口服给药足够时间以减少血清三酰基甘油酯水平。

4. 发明申请

US20110209264A1 EXERCISE SUIT 有权
标题翻译：练习套装
公开(公告)号：US20110209264A1
公开(公告)日：2011-09-01
申请号：US13034240
申请日：2011-02-24
申请人： Dexter Williams , Derrick Johnson , Gregory Moore
发明人： Dexter Williams , Derrick Johnson , Gregory Moore
IPC分类号： A41D13/00
CPC分类号： A41D13/0015
摘要： An exercise suit which includes a resilient band extending through a guide pocket in a first direction along a pant leg or sleeve of the suit. The band engages a direction changing means near the end of the leg or sleeve and at least a portion of the band extends there beyond in a second direction. A free end of the band is releasably engaged with a tension adjustment mechanism provided on the exterior of the leg or sleeve a distance away from the direction changing means. The wearer adjusts the tension in the band by moving a length of the band through the direction changing means and repositioning the free end on the tension adjustment mechanism. A cover is removably disposed over the tension adjustment mechanism to prevent accidental dislodgement of the free end of the band.
摘要翻译：一种运动服，其包括沿着衣服的裤腿或套筒沿第一方向延伸穿过引导口的弹性带。带子接近靠近腿或套筒端部的方向改变装置，并且带的至少一部分在第二方向上延伸到那里。带的自由端可释放地与设置在腿部或套筒的外部上的距离方向改变装置一定距离的张力调节机构接合。穿着者通过使方向改变装置移动带的长度并将自由端重新定位在张力调节机构上来调节带中的张力。盖可拆卸地设置在张力调节机构上以防止带的自由端的意外移动。

5. 发明申请

US20100004431A1 HUMAN EQUIVALENT MONOCLONAL ANTIBODIES ENGINEERED FROM NONHUMAN VARIABLE REGIONS 有权
标题翻译：人类可变区域工程人类等效单克隆抗体
公开(公告)号：US20100004431A1
公开(公告)日：2010-01-07
申请号：US12426785
申请日：2009-04-20
申请人： Matthew J. Bernett , Gregory Moore , John R. Desjarlais
发明人： Matthew J. Bernett , Gregory Moore , John R. Desjarlais
IPC分类号： C07K16/18 , C40B30/04
CPC分类号： C07K16/00 , C07K16/22 , C07K16/2866 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567
摘要： The present invention is directed to the creation of human equivalent CDRs and antibodies containing them by a method of producing an antibody which specifically binds to an antigen.
摘要翻译：本发明涉及通过产生与抗原特异性结合的抗体的方法来产生含有它们的人等效CDR和抗体。

6. 发明申请

US20070015909A1 Adiponectin variants 审中-公开
标题翻译：脂联素变体
公开(公告)号：US20070015909A1
公开(公告)日：2007-01-18
申请号：US11328901
申请日：2006-01-09
申请人： Darian Cash , Arthur Chirino , John Desjarlais , Sergei Ezhevsky , Gregory Moore , Duc-Hahn Nguyen , Jonathan Zalevsky
发明人： Darian Cash , Arthur Chirino , John Desjarlais , Sergei Ezhevsky , Gregory Moore , Duc-Hahn Nguyen , Jonathan Zalevsky
IPC分类号： C07K14/715 , A61K38/17 , C07H21/04
CPC分类号： C07K14/52 , A61K38/00 , C07K14/5759
摘要： Adiponectin variants comprising one or more amino acid modifications to corresponding wild-type adiponectins at positions having predetermined hydrophobicity, predetermined polarity, predetermined electrostatic potential, Met, aromatic amino acid, Cys corresponding to position 152 of SEQ ID NO:1, amino acid affecting isoelectric point of the wild-type or variant adiponectin, amino acid affecting beta sheet formation, helix capping, or dipole interactions, or a combination thereof, wherein the adiponectin variants exhibit improved stability, solubility or soluble expression, expression yield, the ability to induce phosphorylation of AMPK, or a combination thereof, as compared to the corresponding wild-type adiponectins.
摘要翻译：在具有预定疏水性，预定极性，预定静电位，Met，芳香族氨基酸，对应于SEQ ID NO：1的位置152的Cys，影响等电点的氨基酸的位置，包含与相应的野生型脂连蛋白的一个或多个氨基酸修饰的脂连蛋白变体野生型或变体脂联素的点，影响β片形成的氨基酸，螺旋封端或偶极相互作用或其组合，其中脂联素变体表现出改善的稳定性，溶解性或可溶性表达，表达产量，诱导磷酸化的能力的AMPK，或其组合，与相应的野生型脂连蛋白相比。

7. 发明申请

US20060275282A1 Antibodies and Fc fusion proteins with altered immunogenicity 审中-公开
标题翻译：具有改变的免疫原性的抗体和Fc融合蛋白
公开(公告)号：US20060275282A1
公开(公告)日：2006-12-07
申请号：US11332619
申请日：2006-01-12
申请人： Gregory Moore , Shannon Marshall
发明人： Gregory Moore , Shannon Marshall
IPC分类号： A61K39/395 , C07K16/18
CPC分类号： C07K16/00 , C07K2317/24 , C07K2317/52 , C07K2319/30
摘要： Variant antibodies and Fc fusion proteins with reduced immunogenicity are described. In particular, the variants of antibodies and Fc fusion proteins have reduced ability to bind one or more human class II MHC molecules are described.
摘要翻译：描述了具有降低的免疫原性的变体抗体和Fc融合蛋白。特别地，描述了抗体和Fc融合蛋白的变体具有降低的结合一种或多种人II类MHC分子的能力。

8. 发明申请

US20060228759A1 Analysis of MHC-peptide binding interactions 审中-公开
公开(公告)号：US20060228759A1
公开(公告)日：2006-10-12
申请号：US11388642
申请日：2006-03-23
申请人： Umesh Muchhal , John Desjarlais , Gregory Moore
发明人： Umesh Muchhal , John Desjarlais , Gregory Moore
IPC分类号： G01N33/53 , G06F19/00
CPC分类号： G01N33/56977 , G01N33/54306 , G01N33/566 , G01N33/6845 , G01N2333/70539 , G01N2500/04
摘要： Methods, apparatuses, and compounds for screening or detecting binding of candidate peptides to an MHC protein is provided. A first component including at least one candidate peptides and a second component including at least one MHC protein are contacted. One of the components is immobilized on a solid support. The presence, absence, or quantity of binding of the peptide and said MHC protein is then determined.

9. 发明申请

US20060185145A1 Single slitting process for recycling rail 审中-公开
公开(公告)号：US20060185145A1
公开(公告)日：2006-08-24
申请号：US11408135
申请日：2006-04-20
申请人： Gregory Moore , James Melton , Stephen Weaver
发明人： Gregory Moore , James Melton , Stephen Weaver
IPC分类号： B23P6/00 , B23P19/04
CPC分类号： B21B1/0855 , Y10T29/49723 , Y10T29/49725 , Y10T29/4973 , Y10T29/49751 , Y10T29/49753 , Y10T29/49789 , Y10T29/49792 , Y10T29/49995 , Y10T225/10
摘要： A method for recycling rail is provided wherein the rail is heated, and then slit into two pieces. The two pieces are passed through a single mill pass line such that each piece of the rail is deformed to have a generally uniform shape.

10. 发明申请

US20200247862A1 TARGETED HETERODIMERIC FC FUSION PROTEINS CONTAINING IL-15/IL-15RA AND NKG2D ANTIGEN BINDING DOMAINS 审中-公开
公开(公告)号：US20200247862A1
公开(公告)日：2020-08-06
申请号：US16724118
申请日：2019-12-20
申请人： Matthew J. Bernett , John R. Desjarlais , Rajat Varma , Gregory Moore , Juan Diaz , Alex Nisthal , Ke Liu , Rumana Rashid , Eric Chang
发明人： Matthew J. Bernett , John R. Desjarlais , Rajat Varma , Gregory Moore , Juan Diaz , Alex Nisthal , Ke Liu , Rumana Rashid , Eric Chang
IPC分类号： C07K14/54 , C07K16/28 , A61P35/00
摘要： The present invention is directed to a novel targeted heterodimeric Fc fusion proteins comprising an IL-15/IL-15Rα Fc fusion protein and an NKG2D antigen binding domain Fc fusion proteins.

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