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1. 发明授权

US08575254B2 Polylactic acid-based composition and film formed thereof 有权
标题翻译：聚乳酸类组合物及其形成的膜
公开(公告)号：US08575254B2
公开(公告)日：2013-11-05
申请号：US12933905
申请日：2009-03-13
申请人： Gouhei Yamamura , Hiroji Kojima , Masahiro Kimura , Zhengzheng Lai , Bo Liu , Ruoyu Qiu , Tian Xia , Shunji Kono
发明人： Gouhei Yamamura , Hiroji Kojima , Masahiro Kimura , Zhengzheng Lai , Bo Liu , Ruoyu Qiu , Tian Xia , Shunji Kono
IPC分类号： C08K3/32
CPC分类号： C08J5/18 , C08J2367/04 , C08K3/32 , C08K5/29 , C08K5/49 , C08L67/02 , C08L67/04 , C08L2666/18
摘要： A polylactic acid-based composition including a polylactic acid-based resin, a buffering agent; and/or a compound derived from the buffering agent.
摘要翻译：包含聚乳酸类树脂，缓冲剂等的聚乳酸类组合物，和/或衍生自缓冲剂的化合物。

2. 发明申请

US20110028629A1 POLYLACTIC ACID-BASED COMPOSITION AND FILM FORMED THEREOF 有权
标题翻译：基于聚酰胺酸的组合物和其形成的膜
公开(公告)号：US20110028629A1
公开(公告)日：2011-02-03
申请号：US12933905
申请日：2009-03-13
申请人： Gouhei Yamamura , Hiroji Kojima , Masahiro Kimura , Zhengzheng Lai , Bo Liu , Ruoyu Qiu , Tian Xia , Shunji Kono
发明人： Gouhei Yamamura , Hiroji Kojima , Masahiro Kimura , Zhengzheng Lai , Bo Liu , Ruoyu Qiu , Tian Xia , Shunji Kono
IPC分类号： C08K3/32 , C08L67/04 , C08K5/09
CPC分类号： C08J5/18 , C08J2367/04 , C08K3/32 , C08K5/29 , C08K5/49 , C08L67/02 , C08L67/04 , C08L2666/18
摘要： A polylactic acid-based composition including a polylactic acid-based resin, a buffering agent: and/or a compound derived from the buffering agent.
摘要翻译：包含聚乳酸类树脂，缓冲剂和/或由缓冲剂得到的化合物的聚乳酸类组合物。

3. 发明授权

US08673432B2 Aliphatic polyester sheet and molded body composed of the same 有权
标题翻译：脂肪族聚酯片和成型体由其组成
公开(公告)号：US08673432B2
公开(公告)日：2014-03-18
申请号：US12529819
申请日：2008-03-12
申请人： Gouhei Yamamura , Kazuyoshi Nishikawa , Masahiro Kimura , Tian Xia , Zheng Xu , Zhengzheng Lai , Jinglu Chen
发明人： Gouhei Yamamura , Kazuyoshi Nishikawa , Masahiro Kimura , Tian Xia , Zheng Xu , Zhengzheng Lai , Jinglu Chen
IPC分类号： B32B7/00 , B32B7/02 , B32B27/06 , B32B27/18 , B32B27/36 , C08K5/053 , C08K5/16 , C08K5/20
CPC分类号： B32B27/36 , B32B7/02 , B32B7/06 , B32B27/08 , B32B27/16 , B32B27/18 , B32B27/20 , B32B27/22 , B32B27/281 , B32B27/283 , B32B27/285 , B32B27/286 , B32B27/288 , B32B27/308 , B32B27/32 , B32B27/34 , B32B27/38 , B32B27/42 , B32B2250/24 , B32B2255/10 , B32B2270/00 , B32B2307/21 , B32B2307/306 , B32B2307/412 , B32B2307/50 , B32B2307/514 , B32B2307/558 , B32B2307/584 , B32B2307/704 , B32B2307/7163 , B32B2439/00 , B32B2439/70 , B32B2553/00 , C08J5/18 , C08J2367/04 , C08K5/0083 , C08K5/1575 , C08K5/20 , Y10T428/24942 , Y10T428/31786 , C08L67/04
摘要： An aliphatic polyester-based sheet including at least Layer A including an aliphatic polyester, wherein XA of the Layer A is 3-60% and the Layer A contains a crystal nucleating agent and a compound having hydrogen bonding properties with the crystal nucleating agent, and haze of the entire sheet is less than 10%.
摘要翻译：至少包含含有脂肪族聚酯的层A的脂肪族聚酯类片材，其中层A的XA为3-60％，层A含有结晶成核剂和与结晶成核剂具有氢键性质的化合物，以及整个薄片的雾度小于10％。

4. 发明申请

US20100104882A1 ALIPHATIC POLYESTER SHEET AND MOLDED BODY COMPOSED OF THE SAME 有权
标题翻译：复合聚酯片和其组合的模制体
公开(公告)号：US20100104882A1
公开(公告)日：2010-04-29
申请号：US12529819
申请日：2008-03-12
申请人： Gouhei Yamamura , Kazuyoshi Nishikawa , Masahiro Kimura , Tian Xia , Zheng Xu , Zhengzheng Lai , Jinglu Chen
发明人： Gouhei Yamamura , Kazuyoshi Nishikawa , Masahiro Kimura , Tian Xia , Zheng Xu , Zhengzheng Lai , Jinglu Chen
IPC分类号： B32B27/36 , C08L67/00 , C08K5/20 , C08K5/21 , C08L89/00
CPC分类号： B32B27/36 , B32B7/02 , B32B7/06 , B32B27/08 , B32B27/16 , B32B27/18 , B32B27/20 , B32B27/22 , B32B27/281 , B32B27/283 , B32B27/285 , B32B27/286 , B32B27/288 , B32B27/308 , B32B27/32 , B32B27/34 , B32B27/38 , B32B27/42 , B32B2250/24 , B32B2255/10 , B32B2270/00 , B32B2307/21 , B32B2307/306 , B32B2307/412 , B32B2307/50 , B32B2307/514 , B32B2307/558 , B32B2307/584 , B32B2307/704 , B32B2307/7163 , B32B2439/00 , B32B2439/70 , B32B2553/00 , C08J5/18 , C08J2367/04 , C08K5/0083 , C08K5/1575 , C08K5/20 , Y10T428/24942 , Y10T428/31786 , C08L67/04
摘要： An aliphatic polyester-based sheet including at least Layer A including an aliphatic polyester, wherein XA of the Layer A is 3-60% and the Layer A contains a crystal nucleating agent and a compound having hydrogen bonding properties with the crystal nucleating agent, and haze of the entire sheet is less than 10%.
摘要翻译：至少包含含有脂肪族聚酯的层A的脂肪族聚酯类片材，其中层A的XA为3-60％，层A含有结晶成核剂和与结晶成核剂具有氢键性质的化合物，以及整个薄片的雾度小于10％。

5. 发明申请

US20190154826A1 Wideband Ground Penetrating Radar System and Method 审中-公开
公开(公告)号：US20190154826A1
公开(公告)日：2019-05-23
申请号：US16245628
申请日：2019-01-11
申请人： Dryver R. Huston , Tian Xia , Dylan Burns
发明人： Dryver R. Huston , Tian Xia , Dylan Burns
IPC分类号： G01S13/88 , G01S7/282 , G01S7/285 , G01S7/03
摘要： An improved Ground Penetrating Radar (GPR) system is provided. The system advantageously employs full waveform digitization of a returning signal to significantly reduce the number of launch signals and allowing the amount of radiation emitted to stay within the limit set by the Federal Communications Commission (FCC), while producing a robust information detection signal. In addition, intermittent large latent-duty-cycle sampling employs a less expensive digitizer typically used in prior art GPRs. The system is scalable at low-cost to accommodate multi-antenna multi-static testing for subsurface tomographic imaging.

6. 发明授权

US08690839B2 Devices for delivering a medicament and connector for same 有权
标题翻译：用于输送用于其的药物和连接器的装置
公开(公告)号：US08690839B2
公开(公告)日：2014-04-08
申请号：US13709872
申请日：2012-12-10
申请人： Tian Xia , Aaron L. Hirschmann
发明人： Tian Xia , Aaron L. Hirschmann
IPC分类号： A61M31/00
CPC分类号： A61M39/1011 , A61M5/178 , A61M11/06 , A61M15/009 , A61M15/08 , A61M15/085 , A61M25/0041 , A61M25/0097 , A61M31/00 , A61M2202/0468 , A61M2202/048 , A61M2202/064 , A61M2209/06 , A61M2210/0618
摘要： A method and device for delivering medicament such as for ameliorating pain in a patient from an injector superiorly and/or laterally and/or anteriorly towards the sphenopalatine ganglion (SPG). A device for delivering a medicament to a patient in need thereof includes (a) an injector containing a first end configured to remain outside a nasal passage of the patient and a second end configured for entry into the nasal passage of the patient; and (b) an introducer configured for engagement with a nostril of the patient and containing a passageway configured for slidably receiving the injector. The injector is moveable between a storage position preceding the engagement and an engaging position pursuant to the engagement. The device may further include a locking connection assembly that is useful in other devices.
摘要翻译：一种用于递送药物的方法和装置，所述方法和装置例如用于改善患者的疼痛，所述疼痛从注射器向上和/或侧向和/或向前朝向蝶腭神经节（SPG）。一种用于将药物递送到有需要的患者的装置包括（a）注射器，其包含构造成保持在患者鼻通道外部的第一端和构造成进入患者鼻通道的第二端; 和（b）导引器，其构造成用于与患者的鼻孔接合并且包含经配置以可滑动地接收所述注射器的通道。注射器可以在接合之前的存储位置和根据接合的接合位置之间移动。该装置还可以包括在其他装置中有用的锁定连接组件。

7. 发明申请

US20120017893A1 METHODS FOR AMELIORATING PAIN AND DEVICES FOR DELIVERING A MEDICAMENT 有权
标题翻译：用于治疗用于递送药物的疼痛和装置的方法
公开(公告)号：US20120017893A1
公开(公告)日：2012-01-26
申请号：US13247783
申请日：2011-09-28
申请人： Tian Xia
发明人： Tian Xia
IPC分类号： A61M5/00 , A61M11/06
CPC分类号： A61M11/06 , A61M15/08 , A61M15/085 , A61M2202/0468 , A61M2202/048 , A61M2202/064 , A61M2209/06
摘要： A method for delivering medicament such as for ameliorating pain in a patient includes introducing an injector through a nasal passage of the patient into a region substantially medial and/or posterior and/or inferior to a sphenopalatine ganglion (SPG) of the patient; and delivering a medicament from the injector superiorly and/or laterally and/or anteriorly towards the SPG. A device for delivering a medicament to a patient in need thereof includes (a) an injector containing a first end configured to remain outside a nasal passage of the patient and a second end configured for entry into the nasal passage of the patient; and (b) an introducer configured for engagement with a nostril of the patient and containing a passageway configured for slidably receiving the injector. The injector is moveable between a storage position preceding the engagement and an engaging position pursuant to the engagement.
摘要翻译：用于递送药物的方法，例如用于改善患者的疼痛包括将注射器通过患者的鼻通道引入到患者的蝶腭神经节（SPG）的基本内侧和/或后部和/或不足的区域中; 以及从所述注射器向所述SPG递送和/或横向和/或向前投放药物。一种用于将药物递送到有需要的患者的装置包括（a）注射器，其包含构造成保持在患者鼻通道外部的第一端和构造成进入患者鼻通道的第二端; 和（b）导引器，其构造成用于与患者的鼻孔接合并且包含经配置以可滑动地接收所述注射器的通道。注射器可以在接合之前的存储位置和根据接合的接合位置之间移动。

8. 发明申请

US20100310465A1 NANO-DEVICES HAVING RELEASABLE SEALS FOR CONTROLLED RELEASE OF MOLECULES 审中-公开
标题翻译：具有用于控制释放分子的可释放密封件的纳米器件
公开(公告)号：US20100310465A1
公开(公告)日：2010-12-09
申请号：US12841331
申请日：2010-07-22
申请人： Jeffrey I. Zink , Jie Lu , Fuyuhiko Tamanoi , Andre Nel , Sarah Angelos , Fraser Stoddart , Qiaolin Chen , Tian Xia , Kaushik Patel , William Dichtel
发明人： Jeffrey I. Zink , Jie Lu , Fuyuhiko Tamanoi , Andre Nel , Sarah Angelos , Fraser Stoddart , Qiaolin Chen , Tian Xia , Kaushik Patel , William Dichtel
IPC分类号： A61K9/14 , A61K31/352 , A61P27/02 , A61P39/06 , A61P29/00 , A61P37/06 , A61P35/00 , A61P25/08 , A61P31/12 , A61P9/12 , A61P7/02 , B01J19/00 , A61K49/00
CPC分类号： A61K9/5115 , A61K31/352 , A61K47/60 , A61K47/6923 , A61K47/6949 , B82Y5/00 , B82Y30/00
摘要： A nanodevice has a containment vessel defining a storage chamber therein and defining at least one port to provide access to and from said storage chamber, and a stopper assembly attached to the containment vessel. The stopper assembly has a blocking unit arranged proximate the at least one port and has a structure suitable to substantially prevent material after being loaded into the storage chamber from being released while the blocking unit is arranged in a blocking configuration. The stopper assembly is responsive to the presence of a predetermined stimulus such that the blocking unit is released in the presence of the predetermined stimulus to allow the material to be released from the storage chamber. The predetermined stimulus is a predetermined catalytic activity that is suitable to at least one of cleave, hydrolyze, oxidize, or reduce a portion of the stopper assembly, and the nanodevice has a maximum dimension of about 1 μm.
摘要翻译：纳米装置具有容纳容器，在其中限定储存室并且限定至少一个端口以提供与所述储存室的通路，以及附接到所述容纳容器的止动器组件。止动器组件具有靠近所述至少一个端口布置的阻挡单元，并且具有适于基本上防止材料在被装载到储存室中之后被释放的结构，同时阻挡单元被布置成阻挡构造。止动器组件响应于预定刺激的存在，使得阻挡单元在预定刺激的存在下被释放以允许材料从储存室释放。预定的刺激是适合于切割，水解，氧化或减少塞子组件的一部分中的至少一种的预定催化活性，并且纳米装置具有约1μm的最大尺寸。

9. 发明授权

US07701270B2 Structure for a high output resistance, wide swing charge pump 失效
标题翻译：结构为高输出电阻，宽摆电荷泵
公开(公告)号：US07701270B2
公开(公告)日：2010-04-20
申请号：US11845249
申请日：2007-08-27
申请人： Stephen D. Wyatt , Tian Xia
发明人： Stephen D. Wyatt , Tian Xia
IPC分类号： H03L7/06
CPC分类号： H03L7/0896 , H02M3/07 , H03L7/18
摘要： Disclosed are design structures for current sink and source circuits, a charge pump, and a phase locked loop. The current sink and source circuits each have a current mirror that biases a transistor connected to an output node. These circuits each further have a two-stage feedback amplifier to sense the current mirror drain voltage and to control the transistor gate voltage in order to stabilize the current mirror drain voltage independent of output voltage at the output node. The amplifier also increases output resistance at the output node. This configuration allows for a wide operation voltage range and ensures good circuit performance under a very low power supply. A charge pump that incorporates these circuits generates highly matched charging and discharging currents. A PLL that incorporates this charge pump exhibits minimal bandwidth shifts and minimal locking speed and jitter performance degradation.
摘要翻译：公开了电流吸收和电源电路，电荷泵和锁相环的设计结构。电流源和电源电路各自具有偏置连接到输出节点的晶体管的电流镜。这些电路还具有两级反馈放大器以感测电流镜漏极电压并控制晶体管栅极电压，以便稳定电流镜漏极电压，而与输出节点处的输出电压无关。放大器还增加输出节点的输出电阻。该配置允许宽的工作电压范围，并在非常低的电源下确保良好的电路性能。集成这些电路的电荷泵产生高度匹配的充电和放电电流。集成该电荷泵的PLL具有最小的带宽偏移和最小的锁定速度和抖动性能下降。

10. 发明授权

US10350189B2 Method for transnasal delivery of blood-brain barrier permeation agent and therapeutic agent 有权
公开(公告)号：US10350189B2
公开(公告)日：2019-07-16
申请号：US16035833
申请日：2018-07-16
申请人： Tian Xia
发明人： Tian Xia
IPC分类号： A61K31/27 , A61M11/06 , A61K9/00 , A61K45/06 , A61M15/08 , A61M16/08 , A61M11/00 , A61M15/00 , A61M16/04
摘要： Described herein is a method for treating a central nervous system disorder, said method comprising steps of first transnasally administering to or immediately adjacent the sphenopalatine ganglion a first pharmaceutical agent that effectively enhances permeability of the blood-brain barrier; and thereafter administering a second pharmaceutical agent with known efficacious value for action upon central nervous system tissue. The central nervous system disorder may be related directly to the brain or to other central nervous system tissues and cells.

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