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1. 发明申请

US20070031472A1 Steroid-containing sustained release intraocular implants and related methods 有权
标题翻译：类固醇持续释放眼内植入物及相关方法
公开(公告)号：US20070031472A1
公开(公告)日：2007-02-08
申请号：US11474149
申请日：2006-06-23
申请人： Glenn Huang , Thierry Nivaggioli , Lon Spada , Hiroshi Sugimoto , Wendy Blanda , James Chang , Orest Olejnik
发明人： Glenn Huang , Thierry Nivaggioli , Lon Spada , Hiroshi Sugimoto , Wendy Blanda , James Chang , Orest Olejnik
IPC分类号： A61K31/573 , A61F2/02
CPC分类号： A61K9/0051 , A61F9/0017 , A61K9/0024 , A61K9/0092 , A61K9/1647 , A61K9/204 , A61K31/5377 , A61K31/56 , A61K31/573 , A61K31/58 , A61K45/06 , A61K47/593 , A61L27/18 , A61L27/54 , A61L27/58 , A61L31/06 , A61L31/148 , A61L31/16 , A61L2300/222 , A61L2300/436 , A61L2300/45 , A61L2300/604 , A61L2430/16 , A61K2300/00 , C08L67/04
摘要： Biocompatible intraocular implants include a steroid and an auxiliary agent, where the auxiliary agent is present in an amount sufficient to lessen the severity of at least one side effect compared to the use of an otherwise identical implant lacking said auxiliary agent. The steroid and the auxiliary agent may be present on the same intraocular implant or on different implants. The steroid and auxiliary agent may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants containing the steroid and an auxiliary agent may be placed in an eye to treat one or more ocular conditions while reducing the side effects otherwise accompanying steroid use.
摘要翻译：生物相容性眼内植入物包括类固醇和辅助剂，其中与使用缺乏所述辅助剂的其它相同的植入物相比，辅助剂的存在量足以减轻至少一种副作用的严重性。类固醇和辅助剂可以存在于相同的眼内植入物或不同的植入物上。类固醇和辅助剂可以与可生物降解的聚合物基质相结合，例如两种可生物降解的聚合物的基质。或者，类固醇可以与具有一个或多个开口有效以允许类固醇释放到外部环境中的聚合物涂层相关联。包含类固醇和辅助剂的植入物可以放置在眼睛中以治疗一种或多种眼部病症，同时减少否则伴随类固醇使用的副作用。

2. 发明申请

US20050244474A1 Steroid-containing sustained release intraocular implants and related methods 有权
标题翻译：类固醇持续释放眼内植入物及相关方法
公开(公告)号：US20050244474A1
公开(公告)日：2005-11-03
申请号：US11118288
申请日：2005-04-29
申请人： Glenn Huang , Thierry Nivaggioli , Lon Spada , Hiroshi Sugimoto , Wendy Blanda , James Chang , Orest Olejnik
发明人： Glenn Huang , Thierry Nivaggioli , Lon Spada , Hiroshi Sugimoto , Wendy Blanda , James Chang , Orest Olejnik
IPC分类号： A61K9/00 , A61K31/00 , A61K31/573 , A61K45/06 , A61F2/00
CPC分类号： A61K9/0051 , A61K9/0092 , A61K31/573 , A61K31/58 , A61K45/06 , A61K2300/00
摘要： Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months. The steroid may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants may be placed in an eye to treat one or more ocular conditions. The steroid is released from the implant for more than about two months, and may be release for more than several years.
摘要翻译：生物相容性眼内植入物包括彼此相关的类固醇和聚合物，以促进类固醇进入眼睛大于约两个月的时间。类固醇可以与可生物降解的聚合物基质相关联，例如两种可生物降解聚合物的基质。或者，类固醇可以与具有一个或多个开口有效以允许类固醇释放到外部环境中的聚合物涂层相关联。植入物可以放置在眼睛中以治疗一种或多种眼睛状况。类固醇从植入物中释放超过约两个月，可能会释放超过几年。

3. 发明申请

US20050244473A1 Memantine intravitreal implants 审中-公开
标题翻译：美金刚玻璃体内植入物
公开(公告)号：US20050244473A1
公开(公告)日：2005-11-03
申请号：US11117879
申请日：2005-04-29
申请人： Patrick Hughes , Lon Spada , Hiroshi Sugimoto , Wendy Blanda , James Chang
发明人： Patrick Hughes , Lon Spada , Hiroshi Sugimoto , Wendy Blanda , James Chang
IPC分类号： A61K9/00 , A61K31/13 , A61F2/00
CPC分类号： A61K9/0051
摘要： Biocompatible intraocular implants include an anti-excitotoxic agent and a biodegradable polymer that is effective to facilitate release of the anti-excitotoxic agent into an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as retinal damage, including glaucoma and proliferative vitreoretinopathy.
摘要翻译：生物相容性眼内植入物包括抗兴奋性毒性剂和可生物降解的聚合物，其有效促进抗兴奋性毒性剂长时间释放到眼睛中。植入物的治疗剂可以与可生物降解的聚合物基质相关，例如基本上不含聚乙烯醇的基质。植入物可以放置在眼睛中以治疗或减少一种或多种眼部病症的发生，例如视网膜损伤，包括青光眼和增生性玻璃体视网膜病变。

4. 发明授权

US08771722B2 Methods of treating ocular disease using steroid-containing sustained release intraocular implants 有权
标题翻译：使用含类固醇的持续释放眼内植入物治疗眼部疾病的方法
公开(公告)号：US08771722B2
公开(公告)日：2014-07-08
申请号：US13356934
申请日：2012-01-24
申请人： Glenn T. Huang , Thierry Nivaggioli , Lon T. Spada , Hiroshi Sugimoto , Wendy M. Blanda , James N. Chang , Orest Olejnik
发明人： Glenn T. Huang , Thierry Nivaggioli , Lon T. Spada , Hiroshi Sugimoto , Wendy M. Blanda , James N. Chang , Orest Olejnik
IPC分类号： A61F2/14
CPC分类号： A61K9/0051 , A61F9/0017 , A61K9/0024 , A61K9/0092 , A61K9/1647 , A61K9/204 , A61K31/5377 , A61K31/56 , A61K31/573 , A61K31/58 , A61K45/06 , A61K47/593 , A61L27/18 , A61L27/54 , A61L27/58 , A61L31/06 , A61L31/148 , A61L31/16 , A61L2300/222 , A61L2300/436 , A61L2300/45 , A61L2300/604 , A61L2430/16 , A61K2300/00 , C08L67/04
摘要： Biocompatible intraocular implants include a steroid and an auxiliary agent, where the auxiliary agent is present in an amount sufficient to lessen the severity of at least one side effect compared to the use of an otherwise identical implant lacking said auxiliary agent. The steroid and the auxiliary agent may be present on the same intraocular implant or on different implants. The steroid and auxiliary agent may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants containing the steroid and an auxiliary agent may be placed in an eye to treat one or more ocular conditions while reducing the side effects otherwise accompanying steroid use.
摘要翻译：生物相容性眼内植入物包括类固醇和辅助剂，其中与使用缺乏所述辅助剂的其它相同的植入物相比，辅助剂的存在量足以减轻至少一种副作用的严重性。类固醇和辅助剂可以存在于相同的眼内植入物或不同的植入物上。类固醇和辅助剂可以与可生物降解的聚合物基质相结合，例如两种可生物降解的聚合物的基质。或者，类固醇可以与具有一个或多个开口有效以允许类固醇释放到外部环境中的聚合物涂层相关联。包含类固醇和辅助剂的植入物可以放置在眼睛中以治疗一种或多种眼部病症，同时减少否则伴随类固醇使用的副作用。

5. 发明申请

US20120122821A1 STEROID-CONTAINING SUSTAINED RELEASE INTRAOCULAR IMPLANTS AND RELATED METHODS 有权
标题翻译： STEROID含有持续释放内分泌植入物及相关方法
公开(公告)号：US20120122821A1
公开(公告)日：2012-05-17
申请号：US13356934
申请日：2012-01-24
申请人： Glenn T. Huang , Thierry Nivaggioli , Lon T. Spada , Hiroshi Sugimoto , Wendy M. Blanda , James N. Chang , Orest Olejnik
发明人： Glenn T. Huang , Thierry Nivaggioli , Lon T. Spada , Hiroshi Sugimoto , Wendy M. Blanda , James N. Chang , Orest Olejnik
IPC分类号： A61K31/56 , A61K31/6615 , A61P29/00 , A61P27/06 , A61P25/00 , A61K31/573 , A61P27/02
CPC分类号： A61K9/0051 , A61F9/0017 , A61K9/0024 , A61K9/0092 , A61K9/1647 , A61K9/204 , A61K31/5377 , A61K31/56 , A61K31/573 , A61K31/58 , A61K45/06 , A61K47/593 , A61L27/18 , A61L27/54 , A61L27/58 , A61L31/06 , A61L31/148 , A61L31/16 , A61L2300/222 , A61L2300/436 , A61L2300/45 , A61L2300/604 , A61L2430/16 , A61K2300/00 , C08L67/04
摘要： Biocompatible intraocular implants include a steroid and an auxiliary agent, where the auxiliary agent is present in an amount sufficient to lessen the severity of at least one side effect compared to the use of an otherwise identical implant lacking said auxiliary agent. The steroid and the auxiliary agent may be present on the same intraocular implant or on different implants. The steroid and auxiliary agent may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants containing the steroid and an auxiliary agent may be placed in an eye to treat one or more ocular conditions while reducing the side effects otherwise accompanying steroid use.
摘要翻译：生物相容性眼内植入物包括类固醇和辅助剂，其中与使用缺乏所述辅助剂的其它相同的植入物相比，辅助剂的存在量足以减轻至少一种副作用的严重性。类固醇和辅助剂可以存在于相同的眼内植入物或不同的植入物上。类固醇和辅助剂可以与可生物降解的聚合物基质相结合，例如两种可生物降解的聚合物的基质。或者，类固醇可以与具有一个或多个开口有效以允许类固醇释放到外部环境中的聚合物涂层相关联。包含类固醇和辅助剂的植入物可以放置在眼睛中以治疗一种或多种眼部病症，同时减少否则伴随类固醇使用的副作用。

6. 发明授权

US08257730B2 Steroid-containing sustained release intraocular implants and related methods 有权
标题翻译：类固醇持续释放眼内植入物及相关方法
公开(公告)号：US08257730B2
公开(公告)日：2012-09-04
申请号：US11118288
申请日：2005-04-29
申请人： Glenn T. Huang , Thierry Nivaggioli , Lon T. Spada , Hiroshi Sugimoto , Wendy M Blanda , James N. Chang , Orest Olejnik
发明人： Glenn T. Huang , Thierry Nivaggioli , Lon T. Spada , Hiroshi Sugimoto , Wendy M Blanda , James N. Chang , Orest Olejnik
IPC分类号： A61F2/00
CPC分类号： A61K9/0051 , A61K9/0092 , A61K31/573 , A61K31/58 , A61K45/06 , A61K2300/00
摘要： Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months. The steroid may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants may be placed in an eye to treat one or more ocular conditions. The steroid is released from the implant for more than about two months, and may be release for more than several years.
摘要翻译：生物相容性眼内植入物包括彼此相关的类固醇和聚合物，以促进类固醇进入眼睛大于约两个月的时间。类固醇可以与可生物降解的聚合物基质相关联，例如两种可生物降解聚合物的基质。或者，类固醇可以与具有一个或多个开口有效以允许类固醇释放到外部环境中的聚合物涂层相关联。植入物可以放置在眼睛中以治疗一种或多种眼睛状况。类固醇从植入物中释放超过约两个月，可能会释放超过几年。

7. 发明申请

US20080145407A1 METHODS FOR REDUCING NEOVASCULARIZATION OR EDEMA 审中-公开
标题翻译：减少新生血管或EDEMA的方法
公开(公告)号：US20080145407A1
公开(公告)日：2008-06-19
申请号：US11932373
申请日：2007-10-31
申请人： Glenn T. Huang , Thierry Nivaggioli , Lon T. Spada , Hiroshi Sugimoto , Wendy M. Blanda , James N. Chang , Orest Olejnik
发明人： Glenn T. Huang , Thierry Nivaggioli , Lon T. Spada , Hiroshi Sugimoto , Wendy M. Blanda , James N. Chang , Orest Olejnik
IPC分类号： A61F2/16 , A61K31/56 , A61P27/02
CPC分类号： A61K9/0051 , A61F9/0017 , A61K9/0024 , A61K9/0092 , A61K9/1647 , A61K9/204 , A61K31/5377 , A61K31/56 , A61K31/573 , A61K31/58 , A61K45/06 , A61K47/593 , A61L27/18 , A61L27/54 , A61L27/58 , A61L31/06 , A61L31/148 , A61L31/16 , A61L2300/222 , A61L2300/436 , A61L2300/45 , A61L2300/604 , A61L2430/16 , A61K2300/00 , C08L67/04
摘要： Biocompatible intraocular implants include a steroid and an auxiliary agent, where the auxiliary agent is present in an amount sufficient to lessen the severity of at least one side effect compared to the use of an otherwise identical implant lacking said auxiliary agent. The steroid and the auxiliary agent may be present on the same intraocular implant or on different implants. The steroid and auxiliary agent may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants containing the steroid and an auxiliary agent may be placed in an eye to treat one or more ocular conditions while reducing the side effects otherwise accompanying steroid use.
摘要翻译：生物相容性眼内植入物包括类固醇和辅助剂，其中与使用缺乏所述辅助剂的其它相同的植入物相比，辅助剂的存在量足以减轻至少一种副作用的严重性。类固醇和辅助剂可以存在于相同的眼内植入物或不同的植入物上。类固醇和辅助剂可以与可生物降解的聚合物基质相结合，例如两种可生物降解的聚合物的基质。或者，类固醇可以与具有一个或多个开口有效以允许类固醇释放到外部环境中的聚合物涂层相关联。包含类固醇和辅助剂的植入物可以放置在眼睛中以治疗一种或多种眼部病症，同时减少否则伴随类固醇使用的副作用。

8. 发明授权

US08147865B2 Steroid-containing sustained release intraocular implants and related methods 有权
标题翻译：类固醇持续释放眼内植入物及相关方法
公开(公告)号：US08147865B2
公开(公告)日：2012-04-03
申请号：US11474149
申请日：2006-06-23
申请人： Glenn T. Huang , Thierry Nivaggioli , Lon T. Spada , Hiroshi Sugimoto , Wendy M. Blanda , James N. Chang , Orest Olejnik
发明人： Glenn T. Huang , Thierry Nivaggioli , Lon T. Spada , Hiroshi Sugimoto , Wendy M. Blanda , James N. Chang , Orest Olejnik
IPC分类号： A61F2/14
CPC分类号： A61K9/0051 , A61F9/0017 , A61K9/0024 , A61K9/0092 , A61K9/1647 , A61K9/204 , A61K31/5377 , A61K31/56 , A61K31/573 , A61K31/58 , A61K45/06 , A61K47/593 , A61L27/18 , A61L27/54 , A61L27/58 , A61L31/06 , A61L31/148 , A61L31/16 , A61L2300/222 , A61L2300/436 , A61L2300/45 , A61L2300/604 , A61L2430/16 , A61K2300/00 , C08L67/04
摘要： Biocompatible intraocular implants include a steroid and an auxiliary agent, where the auxiliary agent is present in an amount sufficient to lessen the severity of at least one side effect compared to the use of an otherwise identical implant lacking said auxiliary agent. The steroid and the auxiliary agent may be present on the same intraocular implant or on different implants. The steroid and auxiliary agent may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants containing the steroid and an auxiliary agent may be placed in an eye to treat one or more ocular conditions while reducing the side effects otherwise accompanying steroid use.
摘要翻译：生物相容性眼内植入物包括类固醇和辅助剂，其中与使用缺乏所述辅助剂的其它相同的植入物相比，辅助剂的存在量足以减轻至少一种副作用的严重性。类固醇和辅助剂可以存在于相同的眼内植入物或不同的植入物上。类固醇和辅助剂可以与可生物降解的聚合物基质相结合，例如两种可生物降解的聚合物的基质。或者，类固醇可以与具有一个或多个开口有效以允许类固醇释放到外部环境中的聚合物涂层相关联。包含类固醇和辅助剂的植入物可以放置在眼睛中以治疗一种或多种眼部病症，同时减少否则伴随类固醇使用的副作用。

9. 发明申请

US20130299808A1 ORGANIC EL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME 有权
标题翻译：有机EL显示装置及其制造方法
公开(公告)号：US20130299808A1
公开(公告)日：2013-11-14
申请号：US13980310
申请日：2012-01-31
申请人： Hiroshi Sugimoto , Tohru Sonoda
发明人： Hiroshi Sugimoto , Tohru Sonoda
IPC分类号： H01L51/52 , H01L51/56
CPC分类号： H01L51/5203 , H01L27/3258 , H01L51/5271 , H01L51/56 , H01L2251/5323
摘要： In an organic EL display device (100), an insulating layer (113) includes a first insulating film (113a) and a second insulating film (113b) provided thereabove, a plurality of upper electrodes (115c) are each provided to cover a corresponding one of a plurality of organic EL layers (115b), and a reflection film (114) is provided between the first insulating film (113a) and the second insulating film (113b), corresponding to a region N other than the a light emission region. The reflection film (114) reflects toward a sealing substrate (120) a portion of light generated in each organic EL layer (115b) which is diffused into the region N other than the light emission region so that the portion of the light is transmitted through a separation wall portion (116) and the sealing substrate (120) to be viewed as an image on the sealing substrate.
摘要翻译：在有机EL显示装置（100）中，绝缘层（113）包括设置在其上方的第一绝缘膜（113a）和第二绝缘膜（113b），多个上电极（115c）分别设置成覆盖相应的在第一绝缘膜（113a）和第二绝缘膜（113b）之间设置有多个有机EL层（115b）中的一个和反射膜（114），对应于除了发光区域。反射膜（114）朝向密封基板（120）反射在每个有机EL层（115b）中产生的一部分光，其被扩散到除了发光区域之外的区域N中，使得该部分光被透过分隔壁部分（116）和密封基板（120），以被视为密封基板上的图像。

10. 发明授权

US08284300B2 Electronic camera 有权
标题翻译：电子相机
公开(公告)号：US08284300B2
公开(公告)日：2012-10-09
申请号：US12541740
申请日：2009-08-14
申请人： Hiroshi Sugimoto , Takanori Sato
发明人： Hiroshi Sugimoto , Takanori Sato
IPC分类号： H04N5/235
CPC分类号： H04N5/23212 , H04N5/23219 , H04N5/23245 , H04N5/2628
摘要： An electronic camera includes an imaging device. The imaging device has an imaging surface irradiated with an optical image of an object scene. A CPU executes an AF process based on output of an AF evaluating circuit to adjust a position of a focus lens to a position to be optically converged on a specific object present in an object scene. Upon completion of the AF process, the CPU detects a distance from a lens distal end to the specific object by referencing a current position of the focus lens, and further detects brightness information of the object scene based on output of an AE/AWB evaluating circuit. Moreover, the CPU adjusts an imaging parameter by determining whether or not an object scene attribute including the detected distance and brightness information satisfies a predetermined condition.
摘要翻译：电子照相机包括成像装置。成像装置具有用物体场景的光学图像照射的成像表面。 CPU基于AF评估电路的输出执行AF处理，以将聚焦透镜的位置调整到光学会聚在存在于对象场景中的特定对象上的位置。在完成AF处理后，CPU通过参照聚焦透镜的当前位置来检测从透镜远端到特定物体的距离，并且还基于AE / AWB评估电路的输出来检测物体场景的亮度信息。此外，CPU通过确定包括检测到的距离和亮度信息的对象场景属性是否满足预定条件来调整成像参数。

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