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1. 发明申请

WO2004014218A3 IMPLANTABLE OCULAR PUMP TO REDUCE INTRAOCULAR PRESSURE 审中-公开
公开(公告)号：WO2004014218A3
公开(公告)日：2004-02-19
申请号：PCT/US2003/024890
申请日：2003-08-07
申请人： GLAUKOS CORPORATION , SMEDLEY, Gregory , HAFFNER, David , TU, Hosheng , GHARIB, Morteza
发明人： SMEDLEY, Gregory , HAFFNER, David , TU, Hosheng , GHARIB, Morteza
IPC分类号： A61M5/00
摘要： A trabecular pump (40) is implantable in the eye to reduce intraocular pressure. The pump drains aqueous humor from the anterior chamber into outflow pathways, such as Schlemm's canal. A feedback system includes an intraocular pump (54) and a pressure sensor (43/61) in communication with the pump, for regulating intraocular pressure.

2. 发明申请

WO2008061043A3 UVEOSCLERAL SHUNT AND METHODS FOR IMPLANTING SAME 审中-公开
公开(公告)号：WO2008061043A3
公开(公告)日：2008-05-22
申请号：PCT/US2007/084362
申请日：2007-11-09
申请人： GLAUKOS CORPORATION , BURNS, Thomas, W. , HAFFNER, David , HEITZMANN, Harold, A. , FJIELD, Todd, N. , HILL, Richard, A.
发明人： BURNS, Thomas, W. , HAFFNER, David , HEITZMANN, Harold, A. , FJIELD, Todd, N. , HILL, Richard, A.
IPC分类号： A61F9/007
摘要： Devices and methods for treating intraocular pressure are disclosed The devices include shunts for draining aqueous humor from the anterior chamber to the uveoscleral outflow pathway, including the supraciliary space and the suprachoroidal space. The shunts are preferably implanted by ab interno procedures.

3. 发明申请

WO2010093945A2 UVEOSCLERAL DRUG DELIVERY IMPLANT AND METHODS FOR IMPLANTING THE SAME 审中-公开
公开(公告)号：WO2010093945A2
公开(公告)日：2010-08-19
申请号：PCT/US2010/024128
申请日：2010-02-12
申请人： GLAUKOS CORPORATION , HAFFNER, David , CURRY, Kenneth
发明人： HAFFNER, David , CURRY, Kenneth
IPC分类号： A61F9/00 , A61M37/00
CPC分类号： A61F9/00781 , A61F9/0017 , A61K31/00 , A61L27/18 , A61L27/54 , A61L2300/604 , A61L2430/16 , A61M25/00 , A61M25/0105 , A61M27/00 , A61M37/00 , A61M2025/0286 , A61M2210/0612 , C08L67/04
摘要： Devices and methods for treating intraocular pressure are disclosed. The devices include drug delivery implants for treating ocular tissue. Optionally, the devices also include shunts for draining aqueous humor from the anterior chamber to the uveoscleral outflow pathway, including the supraciliary space and the suprachoroidal space. The drug delivery implants can be implanted in ab interno or ab externo procedures.
摘要翻译：公开了用于治疗眼内压的装置和方法。该装置包括用于治疗眼组织的药物递送植入物。可选地，所述装置还包括用于将房水从前房排出至囊肿流出路径的分流器，包括上附近的空间和脉管外空间。药物输送植入物可以以内部或外部程序植入。

4. 发明申请

WO2005016418A1 DEVICES AND METHODS FOR GLAUCOMA TREATMENT 审中-公开
标题翻译： GLAUCOMA治疗的装置和方法
公开(公告)号：WO2005016418A1
公开(公告)日：2005-02-24
申请号：PCT/US2004/024988
申请日：2004-08-03
申请人： GLAUKOS CORPORATION , HAFFNER, David , SMEDLEY, Gregory, T. , TU, Hosheng
发明人： HAFFNER, David , SMEDLEY, Gregory, T. , TU, Hosheng
IPC分类号： A61M5/00
CPC分类号： A61F9/00781
摘要： Intraocular stents (229) and applicators are disclosed for treating glaucoma. The stents (229) are configured to extend between the anterior chamber of the eye and Schlemm's canal (22) for enhancing outflow of aqueous from the anterior chamber (20) so as to reduce intraocular pressure. The stents (229) can have features for anchoring the stent into Schlemm's canal (22) as well as preventing the walls of Schlemm's canal (22) from closing the outlet of the stents (229). The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.
摘要翻译：公开了用于治疗青光眼的眼内支架（229）和敷贴器。支架（229）构造成在眼睛的前房和施乐姆管（22）之间延伸，以增强从前房（20）流出的水分，以便降低眼内压。支架（229）可以具有用于将支架锚定到施莱姆管（22）中的特征，以及阻止施莱姆管（22）的壁关闭支架的出口（229）。施加器可以是可操纵的，以便使植入更容易。此外，施用器可以被配置成保持多个支架，使得可以通过一个切口植入多个支架，而不会从串联注入之间的切口移除施加器。

5. 发明申请

WO2022093832A1 IMPLANT TO TREAT RETINAL VEIN OCCLUSION 审中-公开
公开(公告)号：WO2022093832A1
公开(公告)日：2022-05-05
申请号：PCT/US2021/056665
申请日：2021-10-26
申请人： GLAUKOS CORPORATION
发明人： EVERY, Sean , GUNN, Nicholas , HAFFNER, David , HEITZMANN, Harold
IPC分类号： A61F9/00
摘要： Intraocular implants include a proximal end, a distal end, and a lumen, disposed between the proximal end and the distal end. When implanted into an eye, the proximal end is in fluid communication with a retinal vein of the eye and the distal end is in fluid communication with a choroid of the eye. Via this fluid communication, the intraocular implants treat retinal vein occlusion.

6. 发明申请

WO2021127205A1 OCULAR TISSUE PERFORATION DEVICE 审中-公开
公开(公告)号：WO2021127205A1
公开(公告)日：2021-06-24
申请号：PCT/US2020/065649
申请日：2020-12-17
申请人： GLAUKOS CORPORATION
发明人： GALLARDO, Mark , HAFFNER, David , RANGEL-FRIEDMAN, Gary
IPC分类号： A61F9/007 , A61F9/013 , A61F9/00754 , A61F9/00781
摘要： An instrument to perforate ocular tissue can include a handle configured to be grasped by a user, the handle including a proximal handle end and a distal handle end and a dissection cannula configured for at least partial insertion into a patient eye, wherein the dissection cannula can include a proximal cannula end configured to interface with the handle, a distal cannula or trephine end including an opening into a cannula bore, and an indicator spaced from the distal cannula end at a spacing to indicate or control insertion depth of the distal cannula end into the eye.

7. 发明申请

WO2006036715A2 IMPLANT WITH INTRAOCULAR PRESSURE SENSOR FOR GLAUCOMA TREATMENT 审中-公开
标题翻译：用于GLAUCOMA治疗的内窥镜压力传感器
公开(公告)号：WO2006036715A2
公开(公告)日：2006-04-06
申请号：PCT/US2005/033900
申请日：2005-09-22
申请人： GLAUKOS CORPORATION , HAFFNER, David , TU, Hosheng , MORTEZA, Gharib
发明人： HAFFNER, David , TU, Hosheng , MORTEZA, Gharib
IPC分类号： A61F2/14 , A61M31/00
CPC分类号： A61F9/00781 , A61B3/16
摘要： The invention discloses a trabecular stent and methods for treating glaucoma. The stent may incorporate an intraocular pressure sensor comprising a compressible element that is implanted inside an anterior chamber of an eye, wherein at least one external dimension of the element correlates with intraocular pressure. In some embodiments, the sensor may be coupled to the stent. Also disclosed are methods of delivery of the stent and the sensor to the eye.
摘要翻译：本发明公开了一种小梁支架和治疗青光眼的方法。支架可以包括眼内压力传感器，其包括植入眼睛前房内的可压缩元件，其中该元件的至少一个外部尺寸与眼内压相关。在一些实施例中，传感器可以联接到支架。还公开了将支架和传感器递送到眼睛的方法。

8. 发明授权

EP1545655B1 IMPLANTABLE OCULAR PUMP TO REDUCE INTRAOCULAR PRESSURE 有权
标题翻译：植入目镜泵降低眼内压
公开(公告)号：EP1545655B1
公开(公告)日：2008-12-31
申请号：EP03785064.1
申请日：2003-08-07
申请人： Glaukos Corporation
发明人： SMEDLEY, Gregory , HAFFNER, David , TU, Hosheng , GHARIB, Morteza
IPC分类号： A61M5/00 , A61M37/00 , A61B3/16 , A61B5/00 , A61F9/007 , A61M27/00
CPC分类号： A61F9/00781
摘要： A trabecular pump is implantable in the eye to reduce intraocular pressure. The pump drains aqueous humor from the anterior chamber into outflow pathways, such as Schlemm's canal. A feedback system includes an intraocular pump and a pressure sensor in communication with the pump, for regulating intraocular pressure.

9. 发明授权

EP1651291B1 DEVICES FOR GLAUCOMA TREATMENT 有权转让
标题翻译： DEVICES治疗青光眼
公开(公告)号：EP1651291B1
公开(公告)日：2013-03-13
申请号：EP04779911.9
申请日：2004-08-03
申请人： Glaukos Corporation
发明人： HAFFNER, David , SMEDLEY, Gregory, T. , TU, Hosheng
IPC分类号： A61M5/00 , A61F9/007
CPC分类号： A61F9/00781
摘要： Intraocular stents (229) and applicators are disclosed for treating glaucoma. The stents (229) are configured to extend between the anterior chamber of the eye and Schlemm's canal (22) for enhancing outflow of aqueous from the anterior chamber (20) so as to reduce intraocular pressure. The stents (229) can have features for anchoring the stent into Schlemm's canal (22) as well as preventing the walls of Schlemm's canal (22) from closing the outlet of the stents (229). The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.

10. 发明公开

EP1545655A2 IMPLANTABLE OCULAR PUMP TO REDUCE INTRAOCULAR PRESSURE 有权
标题翻译：植入目镜泵降低眼内压
公开(公告)号：EP1545655A2
公开(公告)日：2005-06-29
申请号：EP03785064.1
申请日：2003-08-07
申请人： Glaukos Corporation
发明人： SMEDLEY, Gregory , HAFFNER, David , TU, Hosheng , GHARIB, Morteza
IPC分类号： A61M5/00 , A61M37/00 , A61B3/16 , A61B5/00
CPC分类号： A61F9/00781
摘要： A trabecular pump (40) is implantable in the eye to reduce intraocular pressure. The pump drains aqueous humor from the anterior chamber into outflow pathways, such as Schlemm's canal. A feedback system includes an intraocular pump (54) and a pressure sensor (43/61) in communication with the pump, for regulating intraocular pressure.

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