专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09045533B2 Membrane transporter NaPi2b (SCL34A2) epitope antibodies 有权
标题翻译：膜转运体NaPi2b（SCL34A2）表位抗体
公开(公告)号：US09045533B2
公开(公告)日：2015-06-02
申请号：US14037504
申请日：2013-09-26
申请人： Gerd Ritter , Beatrice Yin , Anne Murray , George Mark , Lloyd J. Old , Kenneth Lloyd , Serhiy Souchelnytskiy , Ivan Gout , Valeriy Filonenko , Ramziya Kiyamova
发明人： Gerd Ritter , Beatrice Yin , Anne Murray , George Mark , Lloyd J. Old , Kenneth Lloyd , Serhiy Souchelnytskiy , Ivan Gout , Valeriy Filonenko , Ramziya Kiyamova
IPC分类号： C12P21/08 , C12N5/10 , C07K16/18 , C07K16/28 , C07K14/705 , C07K16/30 , A61K39/395 , C07K7/08 , C07K14/47 , A61K39/00
CPC分类号： C07K16/3069 , A61K39/00 , A61K39/0011 , A61K39/39558 , A61K2039/505 , A61K2039/53 , C07K7/08 , C07K14/4748 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/30 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/622 , G01N33/57449 , G01N2333/705 , G01N2500/04
摘要： The present disclosure relates generally to the membrane transporter NaPi2b (SLC34A2) as a target for therapy, including immunotherapy, and particularly cancer therapy. The SLC34A2 epitope peptide encompassing amino acids 312-340 of SLC34A2 has been identified as an ovarian cancer epitope using the monoclonal antibody MX35. The invention also relates to the use of SLC34A2 and particularly SLC34A2 peptides in generating antibodies which have anti-tumor or anti-cancer activity or in stimulating an immunological response. The invention further relates to antibodies specifically directed against NaPi2b (SLC34A2) and the SLC34A2 peptide(s), including veneered, chimeric, single chain and humanized antibodies. Methods for generating an immune response and for treatment of tumors and cancer are also provided. Assays for screening and identifying compounds directed against SLC34A2, including the SLC34A2 epitope peptide, and additional antibodies are provided.
摘要翻译：本公开总体上涉及作为治疗靶标的膜转运体NaPi2b（SLC34A2），包括免疫治疗，特别是癌症治疗。包含SLC34A2的氨基酸312-340的SLC34A2表位肽已经使用单克隆抗体MX35鉴定为卵巢癌表位。本发明还涉及SLC34A2和特别是SLC34A2肽在产生具有抗肿瘤或抗癌活性或刺激免疫应答的抗体中的用途。本发明进一步涉及特异性针对NaPi2b（SLC34A2）和SLC34A2肽的抗体，包括贴面，嵌合，单链和人源化抗体。还提供了产生免疫应答和治疗肿瘤和癌症的方法。提供筛选和鉴定针对SLC34A2的化合物，包括SLC34A2表位肽和其他抗体的测定。

2. 发明申请

US20140157154A1 MANAGING BUSINESS OBJECTS 有权
标题翻译：管理业务对象
公开(公告)号：US20140157154A1
公开(公告)日：2014-06-05
申请号：US13705534
申请日：2012-12-05
申请人： Frank Brunswig , Dirk Giebel , Ralph Rillig , Jens Weiler , Michael Hartel , Daniel Zoch , Gerd Ritter
发明人： Frank Brunswig , Dirk Giebel , Ralph Rillig , Jens Weiler , Michael Hartel , Daniel Zoch , Gerd Ritter
IPC分类号： G06F3/048
CPC分类号： G06Q10/06
摘要： In accordance with aspects of the disclosure, a system and methods are provided for managing business objects in memory. The system and methods may be provided for defining a context of one or more input parameters of data used to determine one or more properties of one or more business objects, defining one or more rules associated with the one or more properties of each business object, and generating a metadata model for each business object based on the context of the one or more input parameters of each business object and the one or more rules associated with the one or more properties of each business object.
摘要翻译：根据本公开的方面，提供了一种用于管理存储器中的业务对象的系统和方法。可以提供系统和方法来定义用于确定一个或多个业务对象的一个或多个属性的数据的一个或多个输入参数的上下文，定义与每个业务对象的一个或多个属性相关联的一个或多个规则，以及基于每个业务对象的一个或多个输入参数的上下文以及与每个业务对象的一个或多个属性相关联的一个或多个规则，为每个业务对象生成元数据模型。

4. 发明授权

US08606723B2 Consistent set of interfaces derived from a business object model 有权
标题翻译：从业务对象模型派生的一组接口
公开(公告)号：US08606723B2
公开(公告)日：2013-12-10
申请号：US11166065
申请日：2005-06-24
申请人： Michael Seubert , Jochen Rasch , Axel Kuehl , Stefan Adelmann , Gabriel Alvarez , Markus Biehler , Daniel Bock , Andreas Bold , Andreas Brossler , Daniel Buchmann , Renzo Colle , Robert Doerner , Stefan Elfner , Stefan Franke , Werner Gnan , Antonia Gross , Patrick Gross , Toralf Grossmann , Gerhard Gschwender , Joerg Hendricks , Wolf Hengevoss , Stephan Hetzer , Christine Hofmann , Volker Jaeck , Bernhard Kelnberger , Johann Kemmer , Joachim Kenntner , Adam Kiwon , Karsten Koetter , Thilo Kraehmer , Corinne Kuster , Christoph Lehner , Werner Liebold , Thomas Maag , Otto Makris , Andreas Morsch , Wolfgang Nieswand , Thomas Nitschke , Dietmar Nowotny , Markus Peter , Georg Podhajsky , Dominic Poetschke , Uwe Pyka , Ruediger Radcke , Frank Reinemuth , Gregor Rieken , Volker Ripp , Gerd Ritter , Paola Sala , Daniela Schapler , Matthias Schmitt , Andreas Schneider , Armulf Schueler , Dagmar Schultze , Reiner Seyler , Ralf Sievers , Gunther Stuhec , Frank Thome , Andre Wagner , Rudolf Winkel , Tao Yu , Jens Zachmann , Renato Zadro , Theo Zimmerman , Michael Zoeller
发明人： Michael Seubert , Jochen Rasch , Axel Kuehl , Stefan Adelmann , Gabriel Alvarez , Markus Biehler , Daniel Bock , Andreas Bold , Andreas Brossler , Daniel Buchmann , Renzo Colle , Robert Doerner , Stefan Elfner , Stefan Franke , Werner Gnan , Antonia Gross , Patrick Gross , Toralf Grossmann , Gerhard Gschwender , Joerg Hendricks , Wolf Hengevoss , Stephan Hetzer , Christine Hofmann , Volker Jaeck , Bernhard Kelnberger , Johann Kemmer , Joachim Kenntner , Adam Kiwon , Karsten Koetter , Thilo Kraehmer , Corinne Kuster , Christoph Lehner , Werner Liebold , Thomas Maag , Otto Makris , Andreas Morsch , Wolfgang Nieswand , Thomas Nitschke , Dietmar Nowotny , Markus Peter , Georg Podhajsky , Dominic Poetschke , Uwe Pyka , Ruediger Radcke , Frank Reinemuth , Gregor Rieken , Volker Ripp , Gerd Ritter , Paola Sala , Daniela Schapler , Matthias Schmitt , Andreas Schneider , Armulf Schueler , Dagmar Schultze , Reiner Seyler , Ralf Sievers , Gunther Stuhec , Frank Thome , Andre Wagner , Rudolf Winkel , Tao Yu , Jens Zachmann , Renato Zadro , Theo Zimmerman , Michael Zoeller
IPC分类号： G06Q10/06 , G06Q10/10 , G06Q40/00
CPC分类号： G06Q30/04
摘要： Methods and systems consistent with the present invention provide a data processing system having a business object model reflecting the data used during a business transaction. Consistent interfaces are generated from the business object model. These interfaces are suitable for use across industries, across businesses, and across different departments within a business during a business transaction.
摘要翻译：与本发明一致的方法和系统提供了一种数据处理系统，其具有反映业务交易中使用的数据的业务对象模型。从业务对象模型生成一致的接口。这些接口适合在业务交易期间跨行业，跨企业以及业务中的不同部门使用。

5. 发明申请

US20130166596A1 USER INTERFACE MODEL DRIVEN DATA ACCESS CONTROL 有权
标题翻译：用户界面模式驱动数据访问控制
公开(公告)号：US20130166596A1
公开(公告)日：2013-06-27
申请号：US13338066
申请日：2011-12-27
申请人： Dirk Stumpf , Tim Kornmann , Gerd Ritter , Rene Gross , Cristina Buchholz , Lambert Boskamp
发明人： Dirk Stumpf , Tim Kornmann , Gerd Ritter , Rene Gross , Cristina Buchholz , Lambert Boskamp
IPC分类号： G06F17/30
CPC分类号： H04L63/102 , G06F2221/2145
摘要： According to one general aspect, a method of retrieving data entities from a backend data device may include maintaining a data model of data entities employed by a user interface. The data model may include a hierarchical relationship between a leading data entity and at least one child data entity. The method may also include authorizing, with an authorization device, when retrieving the leading data entity. The method may include instructing the authorization device that data retrievals of subsequent data entities are to be authorized based upon the authorization of the leading data entity. The method may also include retrieving at least one child data entity of the leading data entity without providing additional authorization credentials.
摘要翻译：根据一个一般方面，从后端数据设备检索数据实体的方法可以包括维护由用户界面采用的数据实体的数据模型。数据模型可以包括领先数据实体和至少一个子数据实体之间的层次关系。该方法还可以包括使用授权设备授权在检索前导数据实体时。该方法可以包括指示授权设备基于领先数据实体的授权来授权后续数据实体的数据检索。该方法还可以包括检索前导数据实体的至少一个子数据实体而不提供附加的授权证书。

6. 发明申请

US20120283115A1 SEROMIC ANALYSIS OF OVARIAN CANCER 审中-公开
标题翻译：卵巢癌的血清分析
公开(公告)号：US20120283115A1
公开(公告)日：2012-11-08
申请号：US13392919
申请日：2010-08-30
申请人： Gerd Ritter , Lloyd J. Old , Constance Old , Sacha Gnjatic , Kunle Odunsi , Dirk Jager
发明人： Gerd Ritter , Lloyd J. Old , Constance Old , Sacha Gnjatic , Kunle Odunsi , Dirk Jager
IPC分类号： G01N33/574 , G01N33/82 , C40B30/04 , G01N21/64 , B82Y15/00
CPC分类号： G01N33/57449 , A61K39/0011 , A61K2039/505 , A61K2039/53 , G01N33/564 , G01N2800/56 , G01N2800/60
摘要： The invention relates to the discovery of cancer antigens associated with ovarian cancer. In further aspects, the invention relates to methods, compositions and kits for the diagnosis and treatment of cancer, particularly ovarian and pancreatic cancers.
摘要翻译：本发明涉及与卵巢癌相关的癌症抗原的发现。在另外的方面，本发明涉及用于诊断和治疗癌症，特别是卵巢和胰腺癌的方法，组合物和试剂盒。

7. 发明授权

US08173102B2 Tame based chelators and uses thereof 失效
标题翻译：温驯的螯合剂及其用途
公开(公告)号：US08173102B2
公开(公告)日：2012-05-08
申请号：US12803835
申请日：2010-07-07
申请人： Enver Arslantas , Richard R. Schmidt , Peter M. Smith-Jones , Gerd Ritter
发明人： Enver Arslantas , Richard R. Schmidt , Peter M. Smith-Jones , Gerd Ritter
IPC分类号： A61K51/00 , A61M36/14
CPC分类号： C07C229/16 , A61K51/0478 , C07C331/28
摘要： New bifunctional chelation complexes are described. These are based on the structure of the so-called “TAME-HexA” molecule. The compounds are especially useful for forming chelation complexes with metal ions, including radioisotopes.
摘要翻译：描述了新的双功能螯合配合物。这些基于所谓的“TAME-HexA”分子的结构。该化合物特别可用于形成与金属离子的螯合络合物，包括放射性同位素。

8. 发明授权

US08142786B2 Method for inducing cell lysis with immunogenic portions of NY-ESO-1 protein 有权
标题翻译：用NY-ESO-1蛋白的免疫原性部分诱导细胞裂解的方法
公开(公告)号：US08142786B2
公开(公告)日：2012-03-27
申请号：US12930522
申请日：2011-01-10
申请人： Alexander Knuth , Elke Jäger , Yao-tseng Chen , Matthew Scanlan , Ali Gure , Gerd Ritter , Lloyd J. Old , Jan W. Drijfhout
发明人： Alexander Knuth , Elke Jäger , Yao-tseng Chen , Matthew Scanlan , Ali Gure , Gerd Ritter , Lloyd J. Old , Jan W. Drijfhout
IPC分类号： A61K38/08 , A61K38/20 , C07K7/00
CPC分类号： C07K14/4748 , A61K38/00 , Y10S435/81
摘要： The invention relates to peptides which bind to MHC Class I and to MHC Class II molecules. These peptides are useful in different therapeutic and diagnostic contexts.
摘要翻译：本发明涉及结合MHC I类和MHC II类分子的肽。这些肽可用于不同的治疗和诊断情境。

9. 发明申请

US20120039892A1 A34 AND A33-LIKE 3 DNA PROTEIN, ANTIBODIES THERETO AND METHODS OF TREATMENT USING SAME 有权
标题翻译： A34和A33-样3 DNA蛋白，抗体及其治疗方法
公开(公告)号：US20120039892A1
公开(公告)日：2012-02-16
申请号：US13233086
申请日：2011-09-15
申请人： Matthew Scanlan , Cynthia H. Scanlan , Gerd Ritter , Lloyd Old , Achim Jungbluth
发明人： Matthew Scanlan , Cynthia H. Scanlan , Gerd Ritter , Lloyd Old , Achim Jungbluth
IPC分类号： A61K39/395 , C07H21/04 , A61P35/00 , C07H21/00
CPC分类号： G01N33/574 , C07K16/2803 , G01N2500/00
摘要： Polynucleotide molecules and polypeptide molecules A34 and A33-like 3 are described, as well as antibodies to polypeptide molecules A34 and A33-like 3. Also described are methods of detecting cancers expressing these polypeptides, and methods and kits for diagnosing said cancers, and methods of inhibiting effects of a cancer in a patient.
摘要翻译：描述了多核苷酸分子和多肽分子A34和A33样3，以及对多肽分子A34和A33样3的抗体。还描述了检测表达这些多肽的癌症的方法，以及用于诊断所述癌症的方法和试剂盒，以及方法抑制癌症在患者中的作用。

10. 发明授权

US08099661B2 Logging and evaluating manual interactions by users to support optimizing and streamlining business processes 有权
标题翻译：记录和评估用户的手动交互，以支持优化和优化业务流程
公开(公告)号：US08099661B2
公开(公告)日：2012-01-17
申请号：US11960666
申请日：2007-12-19
申请人： Gerd Ritter
发明人： Gerd Ritter
IPC分类号： G06F17/00
CPC分类号： G06F17/243 , G06Q10/06 , G06Q10/103 , G06Q30/0224 , G06Q30/0244
摘要： The subject matter disclosed herein provides methods and apparatus, including computer program products, for logging and evaluating activity to support optimizing and streamlining a process, such as a business process. In one aspect, there is provided a computer-implemented method. The method include receiving information representative of activity at a user interface. The received information may be aggregated to form aggregated data. The received information may be evaluated to determine one or more proposals. The evaluation may use the context of a task being performed at the user interface and the activity at the user interface. The one or more proposals may be provided to enable a configuration of a system or a business process with at least one of the proposals. Related apparatus, systems, methods, and articles are also described.
摘要翻译：本文公开的主题提供了用于记录和评估活动以支持优化和简化诸如业务过程之类的过程的计算机程序产品的方法和装置。一方面，提供了一种计算机实现的方法。该方法包括在用户界面处接收表示活动的信息。所收到的信息可以被聚合以形成聚合数据。可以评估所接收的信息以确定一个或多个提案。评估可以使用在用户界面处执行的任务的上下文以及在用户界面处的活动。可以提供一个或多个提案以使得能够利用至少一个提案来配置系统或业务流程。还描述了相关装置，系统，方法和制品。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式